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Items: 17

1.

Temporally Programmed CD8α+ DC Activation Enhances Combination Cancer Immunotherapy.

Tzeng A, Kauke MJ, Zhu EF, Moynihan KD, Opel CF, Yang NJ, Mehta N, Kelly RL, Szeto GL, Overwijk WW, Irvine DJ, Wittrup KD.

Cell Rep. 2016 Dec 6;17(10):2503-2511. doi: 10.1016/j.celrep.2016.11.020.

2.

Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses.

Moynihan KD, Opel CF, Szeto GL, Tzeng A, Zhu EF, Engreitz JM, Williams RT, Rakhra K, Zhang MH, Rothschilds AM, Kumari S, Kelly RL, Kwan BH, Abraham W, Hu K, Mehta NK, Kauke MJ, Suh H, Cochran JR, Lauffenburger DA, Wittrup KD, Irvine DJ.

Nat Med. 2016 Dec;22(12):1402-1410. doi: 10.1038/nm.4200. Epub 2016 Oct 24.

3.

Extraction and analysis of signatures from the Gene Expression Omnibus by the crowd.

Wang Z, Monteiro CD, Jagodnik KM, Fernandez NF, Gundersen GW, Rouillard AD, Jenkins SL, Feldmann AS, Hu KS, McDermott MG, Duan Q, Clark NR, Jones MR, Kou Y, Goff T, Woodland H, Amaral FMR, Szeto GL, Fuchs O, Schüssler-Fiorenza Rose SM, Sharma S, Schwartz U, Bausela XB, Szymkiewicz M, Maroulis V, Salykin A, Barra CM, Kruth CD, Bongio NJ, Mathur V, Todoric RD, Rubin UE, Malatras A, Fulp CT, Galindo JA, Motiejunaite R, Jüschke C, Dishuck PC, Lahl K, Jafari M, Aibar S, Zaravinos A, Steenhuizen LH, Allison LR, Gamallo P, de Andres Segura F, Dae Devlin T, Pérez-García V, Ma'ayan A.

Nat Commun. 2016 Sep 26;7:12846. doi: 10.1038/ncomms12846.

4.

Materials design at the interface of nanoparticles and innate immunity.

Szeto GL, Lavik EB.

J Mater Chem B. 2016 Mar 7;4(9):1610-1618. Epub 2016 Jan 29. No abstract available.

5.

CD4+ T cell-dependent and CD4+ T cell-independent cytokine-chemokine network changes in the immune responses of HIV-infected individuals.

Arnold KB, Szeto GL, Alter G, Irvine DJ, Lauffenburger DA.

Sci Signal. 2015 Oct 20;8(399):ra104. doi: 10.1126/scisignal.aab0808.

6.

Microfluidic squeezing for intracellular antigen loading in polyclonal B-cells as cellular vaccines.

Szeto GL, Van Egeren D, Worku H, Sharei A, Alejandro B, Park C, Frew K, Brefo M, Mao S, Heimann M, Langer R, Jensen K, Irvine DJ.

Sci Rep. 2015 May 22;5:10276. doi: 10.1038/srep10276.

7.

Nanoparticulate STING agonists are potent lymph node-targeted vaccine adjuvants.

Hanson MC, Crespo MP, Abraham W, Moynihan KD, Szeto GL, Chen SH, Melo MB, Mueller S, Irvine DJ.

J Clin Invest. 2015 Jun;125(6):2532-46. doi: 10.1172/JCI79915. Epub 2015 May 4.

8.

Liposomal vaccines incorporating molecular adjuvants and intrastructural T-cell help promote the immunogenicity of HIV membrane-proximal external region peptides.

Hanson MC, Abraham W, Crespo MP, Chen SH, Liu H, Szeto GL, Kim M, Reinherz EL, Irvine DJ.

Vaccine. 2015 Feb 11;33(7):861-8. doi: 10.1016/j.vaccine.2014.12.045. Epub 2015 Jan 2.

9.

Stochastic particle barcoding for single-cell tracking and multiparametric analysis.

Castellarnau M, Szeto GL, Su HW, Tokatlian T, Love JC, Irvine DJ, Voldman J.

Small. 2015 Jan 27;11(4):489-98. doi: 10.1002/smll.201401369. Epub 2014 Sep 2.

10.

Histone deacetylase inhibitors impair the elimination of HIV-infected cells by cytotoxic T-lymphocytes.

Jones RB, O'Connor R, Mueller S, Foley M, Szeto GL, Karel D, Lichterfeld M, Kovacs C, Ostrowski MA, Trocha A, Irvine DJ, Walker BD.

PLoS Pathog. 2014 Aug 14;10(8):e1004287. doi: 10.1371/journal.ppat.1004287. eCollection 2014 Aug.

11.

Attenuation of pathogenic immune responses during infection with human and simian immunodeficiency virus (HIV/SIV) by the tetracycline derivative minocycline.

Drewes JL, Szeto GL, Engle EL, Liao Z, Shearer GM, Zink MC, Graham DR.

PLoS One. 2014 Apr 14;9(4):e94375. doi: 10.1371/journal.pone.0094375. eCollection 2014.

12.

Structure-based programming of lymph-node targeting in molecular vaccines.

Liu H, Moynihan KD, Zheng Y, Szeto GL, Li AV, Huang B, Van Egeren DS, Park C, Irvine DJ.

Nature. 2014 Mar 27;507(7493):519-22. doi: 10.1038/nature12978. Epub 2014 Feb 16.

13.

Koch Institute Symposium on Cancer Immunology and Immunotherapy.

Drake A, Joshi NS, Szeto GL, Zhu E, Eisen HN, Irvine DJ.

Cancer Immunol Res. 2013 Oct;1:217-222.

14.

Engineering synthetic vaccines using cues from natural immunity.

Irvine DJ, Swartz MA, Szeto GL.

Nat Mater. 2013 Nov;12(11):978-90. doi: 10.1038/nmat3775. Review.

15.

Cellular barcodes for efficiently profiling single-cell secretory responses by microengraving.

Yamanaka YJ, Szeto GL, Gierahn TM, Forcier TL, Benedict KF, Brefo MS, Lauffenburger DA, Irvine DJ, Love JC.

Anal Chem. 2012 Dec 18;84(24):10531-6. doi: 10.1021/ac302264q. Epub 2012 Dec 3.

16.

Minocycline suppresses activation of nuclear factor of activated T cells 1 (NFAT1) in human CD4+ T cells.

Szeto GL, Pomerantz JL, Graham DR, Clements JE.

J Biol Chem. 2011 Apr 1;286(13):11275-82. doi: 10.1074/jbc.M110.210518. Epub 2011 Jan 31.

17.

Minocycline attenuates HIV infection and reactivation by suppressing cellular activation in human CD4+ T cells.

Szeto GL, Brice AK, Yang HC, Barber SA, Siliciano RF, Clements JE.

J Infect Dis. 2010 Apr 15;201(8):1132-40. doi: 10.1086/651277.

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