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Items: 1 to 50 of 87

1.

Expansion and impaired mitochondrial efficiency of deep subcutaneous adipose tissue in recent-onset type 2 diabetes.

Bódis K, Jelenik T, Lundbom J, Markgraf DF, Strom A, Zaharia OP, Karusheva Y, Burkart V, Müssig K, Kupriyanova Y, Ouni M, Wolkersdorfer M, Hwang JH, Ziegler D, Schürmann A, Roden M, Szendroedi J; GDS study group.

J Clin Endocrinol Metab. 2019 Dec 15. pii: dgz267. doi: 10.1210/clinem/dgz267. [Epub ahead of print]

PMID:
31838512
2.

Oral Semaglutide and Cardiovascular Outcomes in Type 2 Diabetes.

Zweck E, Westenfeld R, Szendroedi J.

N Engl J Med. 2019 Nov 21;381(21):2075-2076. doi: 10.1056/NEJMc1913157. No abstract available.

PMID:
31747739
3.

Short-term dietary reduction of branched-chain amino acids reduces meal-induced insulin secretion and modifies microbiome composition in type 2 diabetes: a randomized controlled crossover trial.

Karusheva Y, Koessler T, Strassburger K, Markgraf D, Mastrototaro L, Jelenik T, Simon MC, Pesta D, Zaharia OP, Bódis K, Bärenz F, Schmoll D, Wolkersdorfer M, Tura A, Pacini G, Burkart V, Müssig K, Szendroedi J, Roden M.

Am J Clin Nutr. 2019 Nov 1;110(5):1098-1107. doi: 10.1093/ajcn/nqz191.

4.

Diabetes clusters and risk of diabetes-associated diseases - Authors' reply.

Zaharia OP, Kuss O, Strassburger K, Burkart V, Szendroedi J, Roden M.

Lancet Diabetes Endocrinol. 2019 Nov;7(11):828-829. doi: 10.1016/S2213-8587(19)30319-5. No abstract available.

PMID:
31621588
5.

Dynamic changes of muscle insulin sensitivity after metabolic surgery.

Gancheva S, Ouni M, Jelenik T, Koliaki C, Szendroedi J, Toledo FGS, Markgraf DF, Pesta DH, Mastrototaro L, De Filippo E, Herder C, Jähnert M, Weiss J, Strassburger K, Schlensak M, Schürmann A, Roden M.

Nat Commun. 2019 Sep 13;10(1):4179. doi: 10.1038/s41467-019-12081-0.

6.

Augmented Corneal Nerve Fiber Branching in Painful Compared With Painless Diabetic Neuropathy.

Püttgen S, Bönhof GJ, Strom A, Müssig K, Szendroedi J, Roden M, Ziegler D.

J Clin Endocrinol Metab. 2019 Dec 1;104(12):6220-6228. doi: 10.1210/jc.2019-01072.

PMID:
31390004
7.

Risk of diabetes-associated diseases in subgroups of patients with recent-onset diabetes: a 5-year follow-up study.

Zaharia OP, Strassburger K, Strom A, Bönhof GJ, Karusheva Y, Antoniou S, Bódis K, Markgraf DF, Burkart V, Müssig K, Hwang JH, Asplund O, Groop L, Ahlqvist E, Seissler J, Nawroth P, Kopf S, Schmid SM, Stumvoll M, Pfeiffer AFH, Kabisch S, Tselmin S, Häring HU, Ziegler D, Kuss O, Szendroedi J, Roden M; German Diabetes Study Group.

Lancet Diabetes Endocrinol. 2019 Sep;7(9):684-694. doi: 10.1016/S2213-8587(19)30187-1. Epub 2019 Jul 22.

PMID:
31345776
8.

1H-MRS of femoral red and yellow bone marrow fat composition and water content in healthy young men and women at 3 T.

Lundbom J, Bierwagen A, Bodis K, Apostolopoulou M, Szendroedi J, Müssig K, Hwang JH, Roden M.

MAGMA. 2019 Oct;32(5):591-597. doi: 10.1007/s10334-019-00750-6. Epub 2019 May 2.

PMID:
31049821
9.

A New Targeted Lipidomics Approach Reveals Lipid Droplets in Liver, Muscle and Heart as a Repository for Diacylglycerol and Ceramide Species in Non-Alcoholic Fatty Liver.

Preuss C, Jelenik T, Bódis K, Müssig K, Burkart V, Szendroedi J, Roden M, Markgraf DF.

Cells. 2019 Mar 22;8(3). pii: E277. doi: 10.3390/cells8030277.

10.

High-resolution respirometry in human endomyocardial biopsies shows reduced ventricular oxidative capacity related to heart failure.

Scheiber D, Jelenik T, Zweck E, Horn P, Schultheiss HP, Lassner D, Boeken U, Saeed D, Kelm M, Roden M, Westenfeld R, Szendroedi J.

Exp Mol Med. 2019 Feb 14;51(2):16. doi: 10.1038/s12276-019-0214-6.

11.

Correlates of Insulin-Stimulated Glucose Disposal in Recent-Onset Type 1 and Type 2 Diabetes.

Simon MC, Möller-Horigome A, Strassburger K, Nowotny B, Knebel B, Müssig K, Herder C, Szendroedi J, Roden MW; German Diabetes Study Group.

J Clin Endocrinol Metab. 2019 Jun 1;104(6):2295-2304. doi: 10.1210/jc.2018-02057.

PMID:
30689904
12.

An 8-week diet high in cereal fiber and coffee but free of red meat does not improve beta-cell function in patients with type 2 diabetes mellitus: a randomized controlled trial.

Karusheva Y, Kunstein L, Bierwagen A, Nowotny B, Kabisch S, Groener JB, Fleitmann AK, Herder C, Pacini G, Strassburger K, Häring HU, Nawroth PP, Pfeiffer AFH, Burkart V, Müssig K, Roden M, Szendroedi J.

Nutr Metab (Lond). 2018 Dec 29;15:90. doi: 10.1186/s12986-018-0324-5. eCollection 2018.

13.

In vivo 19F MR inflammation imaging after myocardial infarction in a large animal model at 3 T.

Rothe M, Jahn A, Weiss K, Hwang JH, Szendroedi J, Kelm M, Schrader J, Roden M, Flögel U, Bönner F.

MAGMA. 2019 Feb;32(1):5-13. doi: 10.1007/s10334-018-0714-8. Epub 2018 Nov 12.

PMID:
30421248
14.

A variant of the glucose transporter gene SLC2A2 modifies the glycaemic response to metformin therapy in recently diagnosed type 2 diabetes.

Rathmann W, Strassburger K, Bongaerts B, Kuss O, Müssig K, Burkart V, Szendroedi J, Kotzka J, Knebel B, Al-Hasani H, Roden M; GDS Group.

Diabetologia. 2019 Feb;62(2):286-291. doi: 10.1007/s00125-018-4759-z. Epub 2018 Nov 9.

PMID:
30413829
15.

What information needs do people with recently diagnosed diabetes mellitus have and what are the associated factors? A cross-sectional study in Germany.

Grobosch S, Kuske S, Linnenkamp U, Ernstmann N, Stephan A, Genz J, Begun A, Haastert B, Szendroedi J, Müssig K, Burkart V, Roden M, Icks A; GDS Group.

BMJ Open. 2018 Oct 31;8(10):e017895. doi: 10.1136/bmjopen-2017-017895.

16.

Insulin Resistance and Vulnerability to Cardiac Ischemia.

Jelenik T, Flögel U, Álvarez-Hernández E, Scheiber D, Zweck E, Ding Z, Rothe M, Mastrototaro L, Kohlhaas V, Kotzka J, Knebel B, Müller-Wieland D, Moellendorf S, Gödecke A, Kelm M, Westenfeld R, Roden M, Szendroedi J.

Diabetes. 2018 Dec;67(12):2695-2702. doi: 10.2337/db18-0449. Epub 2018 Sep 26.

17.

German Diabetes Study - Baseline data of retinal layer thickness measured by SD-OCT in early diabetes mellitus.

Schröder K, Szendroedi J, Benthin A, Gontscharuk V, Ackermann P, Völker M, Steingrube N, Nowotny B, Ziegler D, Müssig K, Geerling G, Kuß O, Roden M, Guthoff R; GDS Cohort.

Acta Ophthalmol. 2019 Mar;97(2):e303-e307. doi: 10.1111/aos.13851. Epub 2018 Sep 21.

PMID:
30238609
18.

Reduced expression of stearoyl-CoA desaturase-1, but not free fatty acid receptor 2 or 4 in subcutaneous adipose tissue of patients with newly diagnosed type 2 diabetes mellitus.

Bódis K, Kahl S, Simon MC, Zhou Z, Sell H, Knebel B, Tura A, Strassburger K, Burkart V, Müssig K, Markgraf D, Al-Hasani H, Szendroedi J, Roden M; GDS Study Group.

Nutr Diabetes. 2018 Sep 7;8(1):49. doi: 10.1038/s41387-018-0054-9.

19.

Cognitive Function Is Impaired in Patients with Recently Diagnosed Type 2 Diabetes, but Not Type 1 Diabetes.

van Gemert T, Wölwer W, Weber KS, Hoyer A, Strassburger K, Bohnau NT, Brüggen MA, Ovelgönne K, Gössmann EM, Burkart V, Szendroedi J, Roden M, Müssig K; GDS Group .

J Diabetes Res. 2018 Aug 9;2018:1470476. doi: 10.1155/2018/1470476. eCollection 2018.

20.

Metabolic Determinants of Impaired Pulmonary Function in Patients with Newly Diagnosed Type 2 Diabetes Mellitus.

Röhling M, Pesta D, Markgraf DF, Strassburger K, Knebel B, Burkart V, Szendroedi J, Müssig K, Roden M; GDS study group.

Exp Clin Endocrinol Diabetes. 2018 Sep;126(9):584-589. doi: 10.1055/a-0653-7135. Epub 2018 Aug 24.

PMID:
30142673
21.

Habitual Fructose Intake Relates to Insulin Sensitivity and Fatty Liver Index in Recent-Onset Type 2 Diabetes Patients and Individuals without Diabetes.

Weber KS, Simon MC, Strassburger K, Markgraf DF, Buyken AE, Szendroedi J, Müssig K, Roden M; GDS Group.

Nutrients. 2018 Jun 15;10(6). pii: E774. doi: 10.3390/nu10060774.

22.

Meal-derived glucagon responses are related to lower hepatic phosphate concentrations in obesity and type 2 diabetes.

Weber KS, Straßburger K, Fritsch M, Bierwagen A, Koliaki C, Phielix E, Pacini G, Hwang JH, Markgraf DF, Burkart V, Müssig K, Szendroedi J, Roden M.

Diabetes Metab. 2018 Nov;44(5):444-448. doi: 10.1016/j.diabet.2018.05.008. Epub 2018 Jun 2.

PMID:
29910091
23.

Characterization of circulating leukocytes and correlation of leukocyte subsets with metabolic parameters 1 and 5 years after diabetes diagnosis.

Apostolopoulou M, Menart-Houtermans B, Ruetter R, Nowotny B, Gehrmann U, Markgraf D, Szendroedi J, Schloot NC, Roden M.

Acta Diabetol. 2018 Jul;55(7):723-731. doi: 10.1007/s00592-018-1143-x. Epub 2018 Apr 16.

PMID:
29663084
24.

Reduced Myocardial Mitochondrial ROS Production in Mechanically Unloaded Hearts.

Scheiber D, Zweck E, Jelenik T, Horn P, Albermann S, Masyuk M, Boeken U, Saeed D, Kelm M, Roden M, Szendroedi J, Westenfeld R.

J Cardiovasc Transl Res. 2019 Apr;12(2):107-115. doi: 10.1007/s12265-018-9803-3. Epub 2018 Mar 27.

PMID:
29589269
25.

Prediction of clamp-derived insulin sensitivity from the oral glucose insulin sensitivity index.

Tura A, Chemello G, Szendroedi J, Göbl C, Færch K, Vrbíková J, Pacini G, Ferrannini E, Roden M.

Diabetologia. 2018 May;61(5):1135-1141. doi: 10.1007/s00125-018-4568-4. Epub 2018 Feb 26.

PMID:
29484470
26.

Inverse association of insulin antibody levels with insulin sensitivity in adults with Type 1 diabetes.

Burkart V, Strassburger K, Zivehe F, Markgraf D, Herder C, Müssig K, Szendroedi J, Schloot N, Roden M; GDS Group.

Diabet Med. 2018 May;35(5):595-601. doi: 10.1111/dme.13608. Epub 2018 Mar 24.

PMID:
29460298
27.

Association of Lower Cardiovagal Tone and Baroreflex Sensitivity With Higher Liver Fat Content Early in Type 2 Diabetes.

Ziegler D, Strom A, Kupriyanova Y, Bierwagen A, Bönhof GJ, Bódis K, Müssig K, Szendroedi J, Bobrov P, Markgraf DF, Hwang JH, Roden M; GDS Group.

J Clin Endocrinol Metab. 2018 Mar 1;103(3):1130-1138. doi: 10.1210/jc.2017-02294.

PMID:
29267946
28.

Metabolic Characteristics of Recently Diagnosed Adult-Onset Autoimmune Diabetes Mellitus.

Zaharia OP, Bobrov P, Strassburger K, Bódis K, Karusheva Y, Scholz M, Markgraf DF, Burkart V, Schloot NC, Müssig K, Szendroedi J, Roden M; GDS Group.

J Clin Endocrinol Metab. 2018 Feb 1;103(2):429-437. doi: 10.1210/jc.2017-01706.

PMID:
29220505
29.

Lower serum extracellular superoxide dismutase levels are associated with polyneuropathy in recent-onset diabetes.

Strom A, Kaul K, Brüggemann J, Ziegler I, Rokitta I, Püttgen S, Szendroedi J, Müssig K, Roden M, Ziegler D.

Exp Mol Med. 2017 Nov 17;49(11):e394. doi: 10.1038/emm.2017.173.

30.

Differential associations of lower cardiac vagal tone with insulin resistance and insulin secretion in recently diagnosed type 1 and type 2 diabetes.

Ziegler D, Strom A, Bönhof G, Püttgen S, Bódis K, Burkart V, Müssig K, Szendroedi J, Markgraf DF, Roden M; GDS group.

Metabolism. 2018 Feb;79:1-9. doi: 10.1016/j.metabol.2017.10.013. Epub 2017 Nov 4.

PMID:
29113812
31.

Patterns of cutaneous nerve fibre loss and regeneration in type 2 diabetes with painful and painless polyneuropathy.

Bönhof GJ, Strom A, Püttgen S, Ringel B, Brüggemann J, Bódis K, Müssig K, Szendroedi J, Roden M, Ziegler D.

Diabetologia. 2017 Dec;60(12):2495-2503. doi: 10.1007/s00125-017-4438-5. Epub 2017 Sep 15.

PMID:
28914336
32.

Mechanisms of Insulin Resistance in Primary and Secondary Nonalcoholic Fatty Liver.

Jelenik T, Kaul K, Séquaris G, Flögel U, Phielix E, Kotzka J, Knebel B, Fahlbusch P, Hörbelt T, Lehr S, Reinbeck AL, Müller-Wieland D, Esposito I, Shulman GI, Szendroedi J, Roden M.

Diabetes. 2017 Aug;66(8):2241-2253. doi: 10.2337/db16-1147. Epub 2017 May 10.

33.

Impact of insulin sensitivity, beta-cell function and glycaemic control on initiation of second-line glucose-lowering treatment in newly diagnosed type 2 diabetes.

Rathmann W, Strassburger K, Bongaerts B, Bobrov P, Kuss O, Müssig K, Markgraf DF, Szendroedi J, Herder C, Roden M; GDS Group.

Diabetes Obes Metab. 2017 Jun;19(6):866-873. doi: 10.1111/dom.12894. Epub 2017 Feb 23.

PMID:
28127851
34.

Associations between inflammation-related biomarkers and depressive symptoms in individuals with recently diagnosed type 1 and type 2 diabetes.

Herder C, Fürstos JF, Nowotny B, Begun A, Strassburger K, Müssig K, Szendroedi J, Icks A, Roden M; GDS Group.

Brain Behav Immun. 2017 Mar;61:137-145. doi: 10.1016/j.bbi.2016.12.025. Epub 2016 Dec 29.

PMID:
28041985
35.

Circulating adiponectin concentration is inversely associated with glucose tolerance and insulin secretion in people with newly diagnosed diabetes.

Weber KS, Strassburger K, Pacini G, Nowotny B, Müssig K, Szendroedi J, Herder C, Roden M; German Diabetes Study group.

Diabet Med. 2017 Feb;34(2):239-244. doi: 10.1111/dme.13278. Epub 2016 Nov 17.

PMID:
27770592
36.

Associations between explorative dietary patterns and serum lipid levels and their interactions with ApoA5 and ApoE haplotype in patients with recently diagnosed type 2 diabetes.

Weber KS, Knebel B, Strassburger K, Kotzka J, Stehle P, Szendroedi J, Müssig K, Buyken AE, Roden M; GDS Group.

Cardiovasc Diabetol. 2016 Sep 27;15(1):138.

37.

Inflammatory markers are associated with cardiac autonomic dysfunction in recent-onset type 2 diabetes.

Herder C, Schamarek I, Nowotny B, Carstensen-Kirberg M, Straßburger K, Nowotny P, Kannenberg JM, Strom A, Püttgen S, Müssig K, Szendroedi J, Roden M, Ziegler D; German Diabetes Study Group.

Heart. 2017 Jan 1;103(1):63-70. doi: 10.1136/heartjnl-2015-309181. Epub 2016 Aug 1.

PMID:
27481890
38.

Metabolic flexibility and oxidative capacity independently associate with insulin sensitivity in individuals with newly diagnosed type 2 diabetes.

Apostolopoulou M, Strassburger K, Herder C, Knebel B, Kotzka J, Szendroedi J, Roden M; GDS group.

Diabetologia. 2016 Oct;59(10):2203-7. doi: 10.1007/s00125-016-4038-9. Epub 2016 Jul 4.

PMID:
27376543
39.

Variants in Genes Controlling Oxidative Metabolism Contribute to Lower Hepatic ATP Independent of Liver Fat Content in Type 1 Diabetes.

Gancheva S, Bierwagen A, Kaul K, Herder C, Nowotny P, Kahl S, Giani G, Klueppelholz B, Knebel B, Begovatz P, Strassburger K, Al-Hasani H, Lundbom J, Szendroedi J, Roden M; German Diabetes Study (GDS) Group.

Diabetes. 2016 Jul;65(7):1849-57. doi: 10.2337/db16-0162. Epub 2016 Apr 19.

40.

The Impact of Dietary Factors on Glycemic Control, Insulin Sensitivity and Secretion in the First Years after Diagnosis of Diabetes.

Weber KS, Buyken AE, Nowotny B, Strassburger K, Simon MC, Pacini G, Szendroedi J, Müssig K, Roden M; GDS Group.

Exp Clin Endocrinol Diabetes. 2016 Apr;124(4):230-8. doi: 10.1055/s-0035-1569354. Epub 2016 Apr 28.

PMID:
27123782
41.

Cohort profile: the German Diabetes Study (GDS).

Szendroedi J, Saxena A, Weber KS, Strassburger K, Herder C, Burkart V, Nowotny B, Icks A, Kuss O, Ziegler D, Al-Hasani H, Müssig K, Roden M; GDS Group.

Cardiovasc Diabetol. 2016 Apr 7;15:59. doi: 10.1186/s12933-016-0374-9.

42.

Specific Metabolic Profiles and Their Relationship to Insulin Resistance in Recent-Onset Type 1 and Type 2 Diabetes.

Knebel B, Strassburger K, Szendroedi J, Kotzka J, Scheer M, Nowotny B, Müssig K, Lehr S, Pacini G, Finner H, Klüppelholz B, Giani G, Al-Hasani H, Roden M; German Diabetes Study Group.

J Clin Endocrinol Metab. 2016 May;101(5):2130-40. doi: 10.1210/jc.2015-4133. Epub 2016 Feb 1.

PMID:
26829444
43.

Adiponectin, markers of subclinical inflammation and nerve conduction in individuals with recently diagnosed type 1 and type 2 diabetes.

Schamarek I, Herder C, Nowotny B, Carstensen-Kirberg M, Straßburger K, Nowotny P, Strom A, Püttgen S, Müssig K, Szendroedi J, Roden M, Ziegler D; German Diabetes Study Group.

Eur J Endocrinol. 2016 Apr;174(4):433-43. doi: 10.1530/EJE-15-1010. Epub 2016 Jan 5.

PMID:
26733478
44.

Time course of postprandial hepatic phosphorus metabolites in lean, obese, and type 2 diabetes patients.

Fritsch M, Koliaki C, Livingstone R, Phielix E, Bierwagen A, Meisinger M, Jelenik T, Strassburger K, Zimmermann S, Brockmann K, Wolff C, Hwang JH, Szendroedi J, Roden M.

Am J Clin Nutr. 2015 Nov;102(5):1051-8. doi: 10.3945/ajcn.115.107599. Epub 2015 Sep 30.

PMID:
26423389
45.

The Role of Markers of Low-Grade Inflammation for the Early Time Course of Glycemic Control, Glucose Disappearance Rate, and β-Cell Function in Recently Diagnosed Type 1 and Type 2 Diabetes.

Weber KS, Nowotny B, Strassburger K, Pacini G, Müssig K, Szendroedi J, Herder C, Roden M; GDS Group.

Diabetes Care. 2015 Sep;38(9):1758-67. doi: 10.2337/dc15-0169. Epub 2015 Jul 7.

PMID:
26153272
46.

Adaptation of hepatic mitochondrial function in humans with non-alcoholic fatty liver is lost in steatohepatitis.

Koliaki C, Szendroedi J, Kaul K, Jelenik T, Nowotny P, Jankowiak F, Herder C, Carstensen M, Krausch M, Knoefel WT, Schlensak M, Roden M.

Cell Metab. 2015 May 5;21(5):739-46. doi: 10.1016/j.cmet.2015.04.004.

47.

Differential Patterns and Determinants of Cardiac Autonomic Nerve Dysfunction during Endotoxemia and Oral Fat Load in Humans.

Ziegler D, Strom A, Strassburger K, Nowotny B, Zahiragic L, Nowotny PJ, Carstensen-Kirberg M, Herder C, Szendroedi J, Roden M.

PLoS One. 2015 Apr 20;10(4):e0124242. doi: 10.1371/journal.pone.0124242. eCollection 2015.

48.

Effects of intranasal insulin on hepatic fat accumulation and energy metabolism in humans.

Gancheva S, Koliaki C, Bierwagen A, Nowotny P, Heni M, Fritsche A, Häring HU, Szendroedi J, Roden M.

Diabetes. 2015 Jun;64(6):1966-75. doi: 10.2337/db14-0892. Epub 2015 Jan 9.

49.

Perilipin 5: from fatty liver to hepatic lipodystrophy?

Szendroedi J, Roden M.

Hepatology. 2015 Mar;61(3):751-3. doi: 10.1002/hep.27618. Epub 2015 Jan 28. No abstract available.

PMID:
25420909
50.

The H19/let-7 double-negative feedback loop contributes to glucose metabolism in muscle cells.

Gao Y, Wu F, Zhou J, Yan L, Jurczak MJ, Lee HY, Yang L, Mueller M, Zhou XB, Dandolo L, Szendroedi J, Roden M, Flannery C, Taylor H, Carmichael GG, Shulman GI, Huang Y.

Nucleic Acids Res. 2014 Dec 16;42(22):13799-811. doi: 10.1093/nar/gku1160. Epub 2014 Nov 15.

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