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Items: 23

1.

Short Fibrils Constitute the Major Species of Seed-Competent Tau in the Brains of Mice Transgenic for Human P301S Tau.

Jackson SJ, Kerridge C, Cooper J, Cavallini A, Falcon B, Cella CV, Landi A, Szekeres PG, Murray TK, Ahmed Z, Goedert M, Hutton M, O'Neill MJ, Bose S.

J Neurosci. 2016 Jan 20;36(3):762-72. doi: 10.1523/JNEUROSCI.3542-15.2016.

2.

Conformation determines the seeding potencies of native and recombinant Tau aggregates.

Falcon B, Cavallini A, Angers R, Glover S, Murray TK, Barnham L, Jackson S, O'Neill MJ, Isaacs AM, Hutton ML, Szekeres PG, Goedert M, Bose S.

J Biol Chem. 2015 Jan 9;290(2):1049-65. doi: 10.1074/jbc.M114.589309. Epub 2014 Nov 18.

3.

The discovery of a selective, small molecule agonist for the MAS-related gene X1 receptor.

Wroblowski B, Wigglesworth MJ, Szekeres PG, Smith GD, Rahman SS, Nicholson NH, Muir AI, Hall A, Heer JP, Garland SL, Coates WJ.

J Med Chem. 2009 Feb 12;52(3):818-25. doi: 10.1021/jm800962k.

PMID:
19146417
4.

Development of homogeneous 384-well high-throughput screening assays for Abeta1-40 and Abeta1-42 using AlphaScreen technology.

Szekeres PG, Leong K, Day TA, Kingston AE, Karran EH.

J Biomol Screen. 2008 Feb;13(2):101-11. doi: 10.1177/1087057107312778. Epub 2008 Jan 23.

PMID:
18216395
5.

Neuroreplacement, growth factor, and small molecule neurotrophic approaches for treating Parkinson's disease.

O'Neill MJ, Messenger MJ, Lakics V, Murray TK, Karran EH, Szekeres PG, Nisenbaum ES, Merchant KM.

Int Rev Neurobiol. 2007;77:179-217. Review. No abstract available.

PMID:
17178475
6.
7.

Radioligand binding and functional characterization of recombinant human NmU1 and NmU2 receptors stably expressed in clonal human embryonic kidney-293 cells.

Aiyar N, Disa J, Foley JJ, Buckley PT, Wixted WE, Pullen M, Shabon U, Dul E, Szekeres PG, Elshourbagy NA, Sarau HM, Appelbaum E, Bolaky J.

Pharmacology. 2004 Sep;72(1):33-41.

PMID:
15292653
8.

Neuromedin U and its receptors: structure, function, and physiological roles.

Brighton PJ, Szekeres PG, Willars GB.

Pharmacol Rev. 2004 Jun;56(2):231-48. Review.

PMID:
15169928
9.

GPR105, a novel Gi/o-coupled UDP-glucose receptor expressed on brain glia and peripheral immune cells, is regulated by immunologic challenge: possible role in neuroimmune function.

Moore DJ, Murdock PR, Watson JM, Faull RL, Waldvogel HJ, Szekeres PG, Wilson S, Freeman KB, Emson PC.

Brain Res Mol Brain Res. 2003 Oct 21;118(1-2):10-23.

PMID:
14559350
10.

Functional assays for identifying ligands at orphan G protein-coupled receptors.

Szekeres PG.

Receptors Channels. 2002;8(5-6):297-308. Review.

PMID:
12690957
11.

Molecular cloning and characterisation of a novel GABAB-related G-protein coupled receptor.

Calver AR, Michalovich D, Testa TT, Robbins MJ, Jaillard C, Hill J, Szekeres PG, Charles KJ, Jourdain S, Holbrook JD, Boyfield I, Patel N, Medhurst AD, Pangalos MN.

Brain Res Mol Brain Res. 2003 Feb 20;110(2):305-17.

PMID:
12591167
12.

Molecular identification of high and low affinity receptors for nicotinic acid.

Wise A, Foord SM, Fraser NJ, Barnes AA, Elshourbagy N, Eilert M, Ignar DM, Murdock PR, Steplewski K, Green A, Brown AJ, Dowell SJ, Szekeres PG, Hassall DG, Marshall FH, Wilson S, Pike NB.

J Biol Chem. 2003 Mar 14;278(11):9869-74. Epub 2003 Jan 9.

13.

The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids.

Briscoe CP, Tadayyon M, Andrews JL, Benson WG, Chambers JK, Eilert MM, Ellis C, Elshourbagy NA, Goetz AS, Minnick DT, Murdock PR, Sauls HR Jr, Shabon U, Spinage LD, Strum JC, Szekeres PG, Tan KB, Way JM, Ignar DM, Wilson S, Muir AI.

J Biol Chem. 2003 Mar 28;278(13):11303-11. Epub 2002 Dec 19.

14.

The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.

Brown AJ, Goldsworthy SM, Barnes AA, Eilert MM, Tcheang L, Daniels D, Muir AI, Wigglesworth MJ, Kinghorn I, Fraser NJ, Pike NB, Strum JC, Steplewski KM, Murdock PR, Holder JC, Marshall FH, Szekeres PG, Wilson S, Ignar DM, Foord SM, Wise A, Dowell SJ.

J Biol Chem. 2003 Mar 28;278(13):11312-9. Epub 2002 Dec 19.

15.

AXOR12, a novel human G protein-coupled receptor, activated by the peptide KiSS-1.

Muir AI, Chamberlain L, Elshourbagy NA, Michalovich D, Moore DJ, Calamari A, Szekeres PG, Sarau HM, Chambers JK, Murdock P, Steplewski K, Shabon U, Miller JE, Middleton SE, Darker JG, Larminie CG, Wilson S, Bergsma DJ, Emson P, Faull R, Philpott KL, Harrison DC.

J Biol Chem. 2001 Aug 3;276(31):28969-75. Epub 2001 May 31.

16.

Characterization of the binding of [(125)I]-human prolactin releasing peptide (PrRP) to GPR10, a novel G protein coupled receptor.

Langmead CJ, Szekeres PG, Chambers JK, Ratcliffe SJ, Jones DN, Hirst WD, Price GW, Herdon HJ.

Br J Pharmacol. 2000 Oct;131(4):683-8.

17.

Receptor for the pain modulatory neuropeptides FF and AF is an orphan G protein-coupled receptor.

Elshourbagy NA, Ames RS, Fitzgerald LR, Foley JJ, Chambers JK, Szekeres PG, Evans NA, Schmidt DB, Buckley PT, Dytko GM, Murdock PR, Milligan G, Groarke DA, Tan KB, Shabon U, Nuthulaganti P, Wang DY, Wilson S, Bergsma DJ, Sarau HM.

J Biol Chem. 2000 Aug 25;275(34):25965-71.

18.

Neuromedin U is a potent agonist at the orphan G protein-coupled receptor FM3.

Szekeres PG, Muir AI, Spinage LD, Miller JE, Butler SI, Smith A, Rennie GI, Murdock PR, Fitzgerald LR, Wu Hl, McMillan LJ, Guerrera S, Vawter L, Elshourbagy NA, Mooney JL, Bergsma DJ, Wilson S, Chambers JK.

J Biol Chem. 2000 Jul 7;275(27):20247-50.

20.

Endocytosis and recycling of muscarinic receptors.

Edwardson JM, Szekeres PG.

Life Sci. 1999;64(6-7):487-94.

PMID:
10069514
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