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Items: 1 to 50 of 200

1.

Prooxidant modifications in the cryptome of beef jerky, the deleterious post-digestion composition of processed meat snacks.

Serra A, Gallart-Palau X, Koh WY, Chua ZJY, Guo X, Chow CJJ, Chen WM, Park JE, Li T, Tam JP, Sze SK.

Food Res Int. 2019 Nov;125:108569. doi: 10.1016/j.foodres.2019.108569. Epub 2019 Jul 19.

PMID:
31554040
2.

Materials Stiffness-Dependent Redox Metabolic Reprogramming of Mesenchymal Stem Cells for Secretome-Based Therapeutic Angiogenesis.

Yang H, Cheam NMJ, Cao H, Lee MKH, Sze SK, Tan NS, Tay CY.

Adv Healthc Mater. 2019 Sep 18:e1900929. doi: 10.1002/adhm.201900929. [Epub ahead of print]

PMID:
31532923
3.

Abundant neuroprotective chaperone Lipocalin-type prostaglandin D synthase (L-PGDS) disassembles the Amyloid-β fibrils.

Kannaian B, Sharma B, Phillips M, Chowdhury A, Manimekalai MSS, Adav SS, Ng JTY, Kumar A, Lim S, Mu Y, Sze SK, Grüber G, Pervushin K.

Sci Rep. 2019 Aug 29;9(1):12579. doi: 10.1038/s41598-019-48819-5.

4.

Quantitative Proteomic Analysis of Simian Primary Hepatocytes Reveals Candidate Molecular Markers for Permissiveness to Relapsing Malaria Plasmodium cynomolgi.

Dembele L, Gupta DK, Dutta B, Chua ACY, Sze SK, Bifani P.

Proteomics. 2019 Oct;19(19):e1900021. doi: 10.1002/pmic.201900021.

PMID:
31444903
5.

Clinical implications of extracellular vesicles in neurodegenerative diseases.

Vinaiphat A, Sze SK.

Expert Rev Mol Diagn. 2019 Sep;19(9):813-824. doi: 10.1080/14737159.2019.1657407. Epub 2019 Aug 23.

PMID:
31429341
6.

Brown Adipose Tissue: Multimodality Evaluation by PET, MRI, Infrared Thermography, and Whole-Body Calorimetry (TACTICAL-II).

Sun L, Verma S, Michael N, Chan SP, Yan J, Sadananthan SA, Camps SG, Goh HJ, Govindharajulu P, Totman J, Townsend D, Goh JP, Sun L, Boehm BO, Lim SC, Sze SK, Henry CJ, Hu HH, Velan SS, Leow MK.

Obesity (Silver Spring). 2019 Sep;27(9):1434-1442. doi: 10.1002/oby.22560. Epub 2019 Jul 13.

PMID:
31301122
7.

Dynamic expression of tRNA-derived small RNAs define cellular states.

Krishna S, Yim DG, Lakshmanan V, Tirumalai V, Koh JL, Park JE, Cheong JK, Low JL, Lim MJ, Sze SK, Shivaprasad P, Gulyani A, Raghavan S, Palakodeti D, DasGupta R.

EMBO Rep. 2019 Jul;20(7):e47789. doi: 10.15252/embr.201947789. Epub 2019 Jun 12.

8.

Structural determinants for peptide-bond formation by asparaginyl ligases.

Hemu X, El Sahili A, Hu S, Wong K, Chen Y, Wong YH, Zhang X, Serra A, Goh BC, Darwis DA, Chen MW, Sze SK, Liu CF, Lescar J, Tam JP.

Proc Natl Acad Sci U S A. 2019 Jun 11;116(24):11737-11746. doi: 10.1073/pnas.1818568116. Epub 2019 May 23.

PMID:
31123145
9.

Degenerative protein modifications in the aging vasculature and central nervous system: A problem shared is not always halved.

Gallart-Palau X, Tan LM, Serra A, Gao Y, Ho HH, Richards AM, Kandiah N, Chen CP, Kalaria RN, Sze SK.

Ageing Res Rev. 2019 Aug;53:100909. doi: 10.1016/j.arr.2019.100909. Epub 2019 May 19. Review.

PMID:
31116994
10.

Pulsed SILAC-based proteomic analysis unveils hypoxia- and serum starvation-induced de novo protein synthesis with PHD finger protein 14 (PHF14) as a hypoxia sensitive epigenetic regulator in cell cycle progression.

Park JE, Tse SW, Xue G, Assisi C, Maqueda AS, Ramon GPX, Low JK, Kon OL, Tay CY, Tam JP, Sze SK.

Oncotarget. 2019 Mar 15;10(22):2136-2150. doi: 10.18632/oncotarget.26669. eCollection 2019 Mar 15.

11.

Pellino1 specifically binds to phospho-Thr18 of p53 and is recruited to sites of DNA damage.

Dai L, Lin J, Said AB, Yau YH, Shochat SG, Ruiz-Carrillo D, Sun K, Chandrasekaran R, Sze SK, Lescar J, Cheung PC.

Biochem Biophys Res Commun. 2019 Jun 4;513(3):714-720. doi: 10.1016/j.bbrc.2019.03.095. Epub 2019 Apr 12.

PMID:
30987826
12.

Carotid artery disease in post-stroke survivors and effects of enriched environment on stroke pathology in a mouse model of carotid artery stenosis.

Hase Y, Polvikoski TM, Ihara M, Hase M, Zafar R, Stevenson W, Allan LM, Ennaceur A, Horsburgh K, Gallart-Palau X, Sze SK, Kalaria RN.

Neuropathol Appl Neurobiol. 2019 Apr 4. doi: 10.1111/nan.12550. [Epub ahead of print]

PMID:
30947376
13.

Hypoxia-induced tumor exosomes promote M2-like macrophage polarization of infiltrating myeloid cells and microRNA-mediated metabolic shift.

Park JE, Dutta B, Tse SW, Gupta N, Tan CF, Low JK, Yeoh KW, Kon OL, Tam JP, Sze SK.

Oncogene. 2019 Jun;38(26):5158-5173. doi: 10.1038/s41388-019-0782-x. Epub 2019 Mar 12.

PMID:
30872795
14.

Astratides: Insulin-Modulating, Insecticidal, and Antifungal Cysteine-Rich Peptides from Astragalus membranaceus.

Huang J, Wong KH, Tay SV, Serra A, Sze SK, Tam JP.

J Nat Prod. 2019 Feb 22;82(2):194-204. doi: 10.1021/acs.jnatprod.8b00521. Epub 2019 Feb 13.

PMID:
30758201
15.

Immunomic Identification of Malaria Antigens Associated With Protection in Mice.

Siau A, Huang X, Loh HP, Zhang N, Meng W, Sze SK, Renia L, Preiser P.

Mol Cell Proteomics. 2019 May;18(5):837-853. doi: 10.1074/mcp.RA118.000997. Epub 2019 Feb 4.

PMID:
30718293
16.

Delineation of critical amino acids in activation function 1 of progesterone receptor for recruitment of transcription coregulators.

Woo ARE, Sze SK, Chung HH, Lin VC.

Biochim Biophys Acta Gene Regul Mech. 2019 Apr;1862(4):522-533. doi: 10.1016/j.bbagrm.2019.01.004. Epub 2019 Feb 1.

PMID:
30716532
17.

Quantitative profiling brain proteomes revealed mitochondrial dysfunction in Alzheimer's disease.

Adav SS, Park JE, Sze SK.

Mol Brain. 2019 Jan 28;12(1):8. doi: 10.1186/s13041-019-0430-y.

18.

Plant-derived mitochondria-targeting cysteine-rich peptide modulates cellular bioenergetics.

Kam A, Loo S, Dutta B, Sze SK, Tam JP.

J Biol Chem. 2019 Mar 15;294(11):4000-4011. doi: 10.1074/jbc.RA118.006693. Epub 2019 Jan 23.

PMID:
30674551
19.

Artificially intelligent proteomics improves cardiovascular risk assessment.

Sze SK.

EBioMedicine. 2019 Feb;40:23-24. doi: 10.1016/j.ebiom.2019.01.014. Epub 2019 Jan 14. No abstract available.

20.

Brain-derived and circulating vesicle profiles indicate neurovascular unit dysfunction in early Alzheimer's disease.

Gallart-Palau X, Serra A, Hase Y, Tan CF, Chen CP, Kalaria RN, Sze SK.

Brain Pathol. 2019 Sep;29(5):593-605. doi: 10.1111/bpa.12699. Epub 2019 Jan 31.

PMID:
30629763
21.

Mechanoregulation of Cancer-Associated Fibroblast Phenotype in Three-Dimensional Interpenetrating Hydrogel Networks.

Cao H, Lee MKH, Yang H, Sze SK, Tan NS, Tay CY.

Langmuir. 2019 Jun 11;35(23):7487-7495. doi: 10.1021/acs.langmuir.8b02649. Epub 2018 Dec 7.

PMID:
30480453
22.

Amino acids stimulate the endosome-to-Golgi trafficking through Ragulator and small GTPase Arl5.

Shi M, Chen B, Mahajan D, Boh BK, Zhou Y, Dutta B, Tie HC, Sze SK, Wu G, Lu L.

Nat Commun. 2018 Nov 26;9(1):4987. doi: 10.1038/s41467-018-07444-y.

23.

Identification of Arenin, a Novel Kunitz-Like Polypeptide from the Skin Secretions of Dryophytes arenicolor.

Hernández-Pérez J, Serra A, Sze SK, Conway PL, Schlundt J, Benavides J.

Int J Mol Sci. 2018 Nov 19;19(11). pii: E3644. doi: 10.3390/ijms19113644.

24.

Vascular Bed Molecular Profiling by Differential Systemic Decellularization In Vivo.

Serra A, Gallart-Palau X, Park JE, Lim GGY, Lim KL, Ho HH, Tam JP, Sze SK.

Arterioscler Thromb Vasc Biol. 2018 Oct;38(10):2396-2409. doi: 10.1161/ATVBAHA.118.311552.

PMID:
30354219
25.

Bacteria Display Differential Growth and Adhesion Characteristics on Human Hair Shafts.

Kerk SK, Lai HY, Sze SK, Ng KW, Schmidtchen A, Adav SS.

Front Microbiol. 2018 Sep 7;9:2145. doi: 10.3389/fmicb.2018.02145. eCollection 2018.

26.

Importance of TFEB acetylation in control of its transcriptional activity and lysosomal function in response to histone deacetylase inhibitors.

Zhang J, Wang J, Zhou Z, Park JE, Wang L, Wu S, Sun X, Lu L, Wang T, Lin Q, Sze SK, Huang D, Shen HM.

Autophagy. 2018;14(6):1043-1059. doi: 10.1080/15548627.2018.1447290. Epub 2018 Jul 30.

27.

Thrombin and Plasmin Alter the Proteome of Neutrophil Extracellular Traps.

Lim CH, Adav SS, Sze SK, Choong YK, Saravanan R, Schmidtchen A.

Front Immunol. 2018 Jul 9;9:1554. doi: 10.3389/fimmu.2018.01554. eCollection 2018.

28.

Author Correction: PTEN-L is a novel protein phosphatase for ubiquitin dephosphorylation to inhibit PINK1-Parkin-mediated mitophagy.

Wang L, Cho YL, Tang Y, Wang J, Park JE, Wu Y, Wang C, Tong Y, Chawla R, Zhang J, Shi Y, Deng S, Lu G, Wu Y, Tan HW, Pawijit P, Lim GG, Chan HY, Zhang J, Fang L, Yu H, Liou YC, Karthik M, Bay BH, Lim KL, Sze SK, Yap CT, Shen HM.

Cell Res. 2018 Aug;28(8):872-873. doi: 10.1038/s41422-018-0068-9.

29.

Molecular diversity and function of jasmintides from Jasminum sambac.

Kumari G, Wong KH, Serra A, Shin J, Yoon HS, Sze SK, Tam JP.

BMC Plant Biol. 2018 Jul 11;18(1):144. doi: 10.1186/s12870-018-1361-y.

30.

Soy-Derived Phytochemical Genistein Modifies Chromatome Topology to Restrict Cancer Cell Proliferation.

Dutta B, Park JE, Qing ITY, Kon OL, Sze SK.

Proteomics. 2018 Aug;18(16):e1700474. doi: 10.1002/pmic.201700474. Epub 2018 Aug 6.

PMID:
29963755
31.

PTEN-L is a novel protein phosphatase for ubiquitin dephosphorylation to inhibit PINK1-Parkin-mediated mitophagy.

Wang L, Cho YL, Tang Y, Wang J, Park JE, Wu Y, Wang C, Tong Y, Chawla R, Zhang J, Shi Y, Deng S, Lu G, Wu Y, Tan HW, Pawijit P, Lim GG, Chan HY, Zhang J, Fang L, Yu H, Liou YC, Karthik M, Bay BH, Lim KL, Sze SK, Yap CT, Shen HM.

Cell Res. 2018 Aug;28(8):787-802. doi: 10.1038/s41422-018-0056-0. Epub 2018 Jun 22. Erratum in: Cell Res. 2018 Jul 23;:.

32.

Proteomic Analysis of Aqueous Humor from Primary Open Angle Glaucoma Patients on Drug Treatment Revealed Altered Complement Activation Cascade.

Adav SS, Wei J, Terence Y, Ang BCH, Yip LWL, Sze SK.

J Proteome Res. 2018 Jul 6;17(7):2499-2510. doi: 10.1021/acs.jproteome.8b00244. Epub 2018 Jun 26.

PMID:
29901396
33.

Online Removal of Sodium Dodecyl Sulfate via Weak Cation Exchange in Liquid Chromatography-Mass Spectrometry Based Proteomics.

Serra A, Gallart-Palau X, Dutta B, Sze SK.

J Proteome Res. 2018 Jul 6;17(7):2390-2400. doi: 10.1021/acs.jproteome.8b00156. Epub 2018 Jun 20.

PMID:
29888605
34.

Transcriptome alterations of vascular smooth muscle cells in aortic wall of myocardial infarction patients.

Wongsurawat T, Woo CC, Giannakakis A, Lin XY, Cheow ESH, Lee CN, Richards M, Sze SK, Nookaew I, Kuznetsov VA, Sorokin V.

Data Brief. 2018 Feb 6;17:1112-1135. doi: 10.1016/j.dib.2018.01.108. eCollection 2018 Apr.

35.

The protein kinase CK2 catalytic domain from Plasmodium falciparum: crystal structure, tyrosine kinase activity and inhibition.

Ruiz-Carrillo D, Lin J, El Sahili A, Wei M, Sze SK, Cheung PCF, Doerig C, Lescar J.

Sci Rep. 2018 May 9;8(1):7365. doi: 10.1038/s41598-018-25738-5.

36.

Ribosome protection by antibiotic resistance ATP-binding cassette protein.

Su W, Kumar V, Ding Y, Ero R, Serra A, Lee BST, Wong ASW, Shi J, Sze SK, Yang L, Gao YG.

Proc Natl Acad Sci U S A. 2018 May 15;115(20):5157-5162. doi: 10.1073/pnas.1803313115. Epub 2018 Apr 30.

37.

Identification of Antibacterial Components in Human Hair Shafts.

Subbaiah RS, Kerk SK, Lian Y, Lunny D, Sze SK, Ng KW, Schmidtchen A, Adav SS.

Acta Derm Venereol. 2018 Jul 11;98(7):708-710. doi: 10.2340/00015555-2952. No abstract available.

38.

Aqueous humor protein dysregulation in primary angle-closure glaucoma.

Adav SS, Wei J, Qian J, Gan NY, Yip LWL, Sze SK.

Int Ophthalmol. 2019 Apr;39(4):861-871. doi: 10.1007/s10792-018-0885-3. Epub 2018 Mar 13.

PMID:
29536409
39.

Peptidomic Identification of Cysteine-Rich Peptides from Plants.

Hemu X, Serra A, Darwis DA, Cornvik T, Sze SK, Tam JP.

Methods Mol Biol. 2018;1719:379-393. doi: 10.1007/978-1-4939-7537-2_26.

PMID:
29476526
40.

Distinctive molecular signature and activated signaling pathways in aortic smooth muscle cells of patients with myocardial infarction.

Wongsurawat T, Woo CC, Giannakakis A, Lin XY, Cheow ESH, Lee CN, Richards M, Sze SK, Nookaew I, Kuznetsov VA, Sorokin V.

Atherosclerosis. 2018 Apr;271:237-244. doi: 10.1016/j.atherosclerosis.2018.01.024. Epub 2018 Jan 31.

41.

Capsinoids activate brown adipose tissue (BAT) with increased energy expenditure associated with subthreshold 18-fluorine fluorodeoxyglucose uptake in BAT-positive humans confirmed by positron emission tomography scan.

Sun L, Camps SG, Goh HJ, Govindharajulu P, Schaefferkoetter JD, Townsend DW, Verma SK, Velan SS, Sun L, Sze SK, Lim SC, Boehm BO, Henry CJ, Leow MK.

Am J Clin Nutr. 2018 Jan 1;107(1):62-70. doi: 10.1093/ajcn/nqx025.

PMID:
29381803
42.

Studies on the Proteome of Human Hair - Identification of Histones and Deamidated Keratins.

Adav SS, Subbaiaih RS, Kerk SK, Lee AY, Lai HY, Ng KW, Sze SK, Schmidtchen A.

Sci Rep. 2018 Jan 25;8(1):1599. doi: 10.1038/s41598-018-20041-9.

43.

Lowering Low-Density Lipoprotein Particles in Plasma Using Dextran Sulphate Co-Precipitates Procoagulant Extracellular Vesicles.

Wang JW, Zhang YN, Sze SK, van de Weg SM, Vernooij F, Schoneveld AH, Tan SH, Versteeg HH, Timmers L, Lam CSP, de Kleijn DPV.

Int J Mol Sci. 2017 Dec 29;19(1). pii: E94. doi: 10.3390/ijms19010094.

44.

Quantitative mass spectrometry of human reticulocytes reveal proteome-wide modifications during maturation.

Chu TTT, Sinha A, Malleret B, Suwanarusk R, Park JE, Naidu R, Das R, Dutta B, Ong ST, Verma NK, Chan JK, Nosten F, Rénia L, Sze SK, Russell B, Chandramohanadas R.

Br J Haematol. 2018 Jan;180(1):118-133. doi: 10.1111/bjh.14976. Epub 2017 Nov 2.

PMID:
29094334
45.

Myocardial Injury Is Distinguished from Stable Angina by a Set of Candidate Plasma Biomarkers Identified Using iTRAQ/MRM-Based Approach.

Cheow ESH, Cheng WC, Yap T, Dutta B, Lee CN, Kleijn DPV, Sorokin V, Sze SK.

J Proteome Res. 2018 Jan 5;17(1):499-515. doi: 10.1021/acs.jproteome.7b00651. Epub 2017 Nov 7.

PMID:
29068691
46.

Enriched Expression of Neutral Sphingomyelinase 2 in the Striatum is Essential for Regulation of Lipid Raft Content and Motor Coordination.

Tan LH, Tan AJ, Ng YY, Chua JJ, Chew WS, Muralidharan S, Torta F, Dutta B, Sze SK, Herr DR, Ong WY.

Mol Neurobiol. 2018 Jul;55(7):5741-5756. doi: 10.1007/s12035-017-0784-z. Epub 2017 Oct 17.

47.

Proteolytic signatures define unique thrombin-derived peptides present in human wound fluid in vivo.

Saravanan R, Adav SS, Choong YK, van der Plas MJA, Petrlova J, Kjellström S, Sze SK, Schmidtchen A.

Sci Rep. 2017 Oct 13;7(1):13136. doi: 10.1038/s41598-017-13197-3.

48.

Alternative SET/TAFI Promoters Regulate Embryonic Stem Cell Differentiation.

Edupuganti RR, Harikumar A, Aaronson Y, Biran A, Sailaja BS, Nissim-Rafinia M, Azad GK, Cohen MA, Park JE, Shivalila CS, Markoulaki S, Sze SK, Jaenisch R, Meshorer E.

Stem Cell Reports. 2017 Oct 10;9(4):1291-1303. doi: 10.1016/j.stemcr.2017.08.021. Epub 2017 Sep 28.

49.

Brain ureido degenerative protein modifications are associated with neuroinflammation and proteinopathy in Alzheimer's disease with cerebrovascular disease.

Gallart-Palau X, Serra A, Lee BST, Guo X, Sze SK.

J Neuroinflammation. 2017 Sep 2;14(1):175. doi: 10.1186/s12974-017-0946-y.

50.

An iTRAQ-based proteomic analysis reveals dysregulation of neocortical synaptopodin in Lewy body dementias.

Datta A, Chai YL, Tan JM, Lee JH, Francis PT, Chen CP, Sze SK, Lai MKP.

Mol Brain. 2017 Aug 11;10(1):36. doi: 10.1186/s13041-017-0316-9.

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