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Items: 41

1.

Access and concentrations of atorvastatin in the prostate in men with prostate cancer.

Knuuttila E, Riikonen J, Syvälä H, Auriola S, Murtola TJ.

Prostate. 2019 Sep;79(12):1412-1419. doi: 10.1002/pros.23863. Epub 2019 Jun 24.

PMID:
31231865
3.

Atorvastatin Versus Placebo for Prostate Cancer Before Radical Prostatectomy-A Randomized, Double-blind, Placebo-controlled Clinical Trial.

Murtola TJ, Syvälä H, Tolonen T, Helminen M, Riikonen J, Koskimäki J, Pakarainen T, Kaipia A, Isotalo T, Kujala P, Tammela TLJ.

Eur Urol. 2018 Dec;74(6):697-701. doi: 10.1016/j.eururo.2018.06.037. Epub 2018 Jul 18.

PMID:
30031572
4.

Additive inhibitory effects of simvastatin and enzalutamide on androgen-sensitive LNCaP and VCaP prostate cancer cells.

Syvälä H, Pennanen P, Bläuer M, Tammela TL, Murtola TJ.

Biochem Biophys Res Commun. 2016 Dec 2;481(1-2):46-50. doi: 10.1016/j.bbrc.2016.11.021. Epub 2016 Nov 8.

PMID:
27833018
5.

The effects of metformin and simvastatin on the growth of LNCaP and RWPE-1 prostate epithelial cell lines.

Pennanen P, Syvälä H, Bläuer M, Savinainen K, Ylikomi T, Tammela TLJ, Murtola TJ.

Eur J Pharmacol. 2016 Oct 5;788:160-167. doi: 10.1016/j.ejphar.2016.06.036. Epub 2016 Jun 21.

PMID:
27341997
6.

The importance of LDL and cholesterol metabolism for prostate epithelial cell growth.

Murtola TJ, Syvälä H, Pennanen P, Bläuer M, Solakivi T, Ylikomi T, Tammela TL.

PLoS One. 2012;7(6):e39445. doi: 10.1371/journal.pone.0039445. Epub 2012 Jun 27.

7.

Comparative effects of high and low-dose simvastatin on prostate epithelial cells: the role of LDL.

Murtola TJ, Syvälä H, Pennanen P, Bläuer M, Solakivi T, Ylikomi T, Tammela TL.

Eur J Pharmacol. 2011 Dec 30;673(1-3):96-100. doi: 10.1016/j.ejphar.2011.10.022. Epub 2011 Oct 25.

PMID:
22040920
8.

Postconditioning and remote postconditioning of ischemic rat cardiac grafts.

Tang Y, Mennander A, Oksala N, Atalay M, Syvala H, Lagerstedt A, Kuuslahti M, Nieminen R, Anas N, Moilanen E, Tarkka M.

Eur Surg Res. 2010;45(1):1-8. doi: 10.1159/000315479. Epub 2010 Jul 13.

PMID:
20628256
9.

Vestibular dysfunction in vitamin D receptor mutant mice.

Minasyan A, Keisala T, Zou J, Zhang Y, Toppila E, Syvälä H, Lou YR, Kalueff AV, Pyykkö I, Tuohimaa P.

J Steroid Biochem Mol Biol. 2009 Apr;114(3-5):161-6. doi: 10.1016/j.jsbmb.2009.01.020. Epub 2009 Feb 6.

PMID:
19429446
10.

Effects of simvastatin, acetylsalicylic acid, and rosiglitazone on proliferation of normal and cancerous prostate epithelial cells at therapeutic concentrations.

Murtola TJ, Pennanen P, Syvälä H, Bläuer M, Ylikomi T, Tammela TL.

Prostate. 2009 Jun 15;69(9):1017-23. doi: 10.1002/pros.20951.

PMID:
19301305
11.

Statins and prostate cancer prevention: where we are now, and future directions.

Murtola TJ, Visakorpi T, Lahtela J, Syvälä H, Tammela TLj.

Nat Clin Pract Urol. 2008 Jul;5(7):376-87. doi: 10.1038/ncpuro1146. Epub 2008 Jun 10. Review.

PMID:
18542103
12.

Interaction of factors related to the metabolic syndrome and vitamin D on risk of prostate cancer.

Tuohimaa P, Tenkanen L, Syvälä H, Lumme S, Hakulinen T, Dillner J, Hakama M.

Cancer Epidemiol Biomarkers Prev. 2007 Feb;16(2):302-7.

13.

Altered levels of Smad2 and Smad4 are associated with human prostate carcinogenesis.

Perttu MC, Martikainen PM, Huhtala HS, Bläuer M, Tammela TL, Tuohimaa PJ, Syvälä H.

Prostate Cancer Prostatic Dis. 2006;9(2):185-9. Epub 2006 Mar 21.

PMID:
16550207
14.

Calcidiol and prostate cancer.

Tuohimaa P, Golovko O, Kalueff A, Nazarova N, Qiao S, Syvälä H, Talonpoika R, Lou YR.

J Steroid Biochem Mol Biol. 2005 Feb;93(2-5):183-90. Epub 2005 Jan 22. Review.

PMID:
15860261
15.

The role of Vitamin D3 metabolism in prostate cancer.

Lou YR, Qiao S, Talonpoika R, Syvälä H, Tuohimaa P.

J Steroid Biochem Mol Biol. 2004 Nov;92(4):317-25. Epub 2004 Dec 19. Review.

PMID:
15663995
16.

25-hydroxyvitamin D3 is an active hormone in human primary prostatic stromal cells.

Lou YR, Laaksi I, Syvälä H, Bläuer M, Tammela TL, Ylikomi T, Tuohimaa P.

FASEB J. 2004 Feb;18(2):332-4. Epub 2003 Dec 4.

PMID:
14657005
17.

Role of 24-hydroxylase in vitamin D3 growth response of OVCAR-3 ovarian cancer cells.

Miettinen S, Ahonen MH, Lou YR, Manninen T, Tuohimaa P, Syvälä H, Ylikomi T.

Int J Cancer. 2004 Jan 20;108(3):367-73.

18.

Suppression of immunoreactive macrophages in atheromatous lesions of rabbits by clodronate.

Ylitalo R, Syvälä H, Tuohimaa P, Ylitalo P.

Pharmacol Toxicol. 2002 Mar;90(3):139-43.

PMID:
12071335
19.

Expression of progesterone receptor isoforms A and B is differentially regulated by estrogen in different breast cancer cell lines.

Vienonen A, Syvälä H, Miettinen S, Tuohimaa P, Ylikomi T.

J Steroid Biochem Mol Biol. 2002 Mar;80(3):307-13.

PMID:
11948015
20.

Antiproliferative action of vitamin D.

Ylikomi T, Laaksi I, Lou YR, Martikainen P, Miettinen S, Pennanen P, Purmonen S, Syvälä H, Vienonen A, Tuohimaa P.

Vitam Horm. 2002;64:357-406. Review.

PMID:
11898396
21.

The C-terminal half of Hsp90 is responsible for its cytoplasmic localization.

Passinen S, Valkila J, Manninen T, Syvälä H, Ylikomi T.

Eur J Biochem. 2001 Oct;268(20):5337-42.

22.

Heat shock protein 90 and the nuclear transport of progesterone receptor.

Haverinen M, Passinen S, Syvälä H, Pasanen S, Manninen T, Tuohimaa P, Ylikomi T.

Cell Stress Chaperones. 2001 Jul;6(3):256-62.

23.

Vitamin D and prostate cancer.

Tuohimaa P, Lyakhovich A, Aksenov N, Pennanen P, Syvälä H, Lou YR, Ahonen M, Hasan T, Pasanen P, Bläuer M, Manninen T, Miettinen S, Vilja P, Ylikomi T.

J Steroid Biochem Mol Biol. 2001 Jan-Mar;76(1-5):125-34.

PMID:
11384870
24.

Vitamin D induced up-regulation of keratinocyte growth factor (FGF-7/KGF) in MCF-7 human breast cancer cells.

Lyakhovich A, Aksenov N, Pennanen P, Miettinen S, Ahonen MH, Syvälä H, Ylikomi T, Tuohimaa P.

Biochem Biophys Res Commun. 2000 Jul 5;273(2):675-80.

PMID:
10873663
25.

Inhibin and activin subunits and spermatogenesis.

Tuohimaa P, Zhuang YH, Ylikomi T, Syvälä H, Bläuer M.

Andrologia. 2000 Jan;32(1):48-52. Review. No abstract available.

PMID:
10702867
26.

Distribution of progesterone receptor in female mouse tissues.

Uotinen N, Puustinen R, Pasanen S, Manninen T, Kivineva M, Syvälä H, Tuohimaa P, Ylikomi T.

Gen Comp Endocrinol. 1999 Sep;115(3):429-41.

PMID:
10480995
27.

Only a small portion of the cytoplasmic progesterone receptor is associated with Hsp90 in vivo.

Passinen S, Haverinen M, Pekki A, Rauta J, Paranko J, Syvälä H, Tuohimaa P, Ylikomi T.

J Cell Biochem. 1999 Sep 1;74(3):458-67.

PMID:
10412046
28.

Identification of a nuclear localization signal in activin/inhibin betaA subunit; intranuclear betaA in rat spermatogenic cells.

Bläuer M, Husgafvel S, Syvälä H, Tuohimaa P, Ylikomi T.

Biol Reprod. 1999 Mar;60(3):588-93.

PMID:
10026103
29.

Reappraisal of the role of heat shock proteins as regulators of steroid receptor activity.

Ylikomi T, Wurtz JM, Syvälä H, Passinen S, Pekki A, Haverinen M, Bläuer M, Tuohimaa P, Gronemeyer H.

Crit Rev Biochem Mol Biol. 1998;33(6):437-66. Review.

PMID:
9918514
30.

Evidence for enhanced ubiquitin-mediated proteolysis of the chicken progesterone receptor by progesterone.

Syvälä H, Vienonen A, Zhuang YH, Kivineva M, Ylikomi T, Tuohimaa P.

Life Sci. 1998;63(17):1505-12.

PMID:
9808061
31.

Progesterone receptor in chicken bursa of Fabricius and thymus: evidence for expression in B-lymphocytes.

Pasanen S, Ylikomi T, Palojoki E, Syvälä H, Pelto-Huikko M, Tuohimaa P.

Mol Cell Endocrinol. 1998 Jun 25;141(1-2):119-28.

PMID:
9723893
32.

Localization of 1,25-dihydroxyvitamin D3 receptor (VDR) expression in human prostate.

Kivineva M, Bläuer M, Syvälä H, Tammela T, Tuohimaa P.

J Steroid Biochem Mol Biol. 1998 Aug;66(3):121-7.

PMID:
9719446
33.

Distribution of progesterone receptor in chicken: novel target organs for progesterone and estrogen action.

Pasanen S, Ylikomi T, Syvälä H, Tuohimaa P.

Mol Cell Endocrinol. 1997 Nov 30;135(1):79-91.

PMID:
9453243
34.

Expression of the chicken progesterone receptor forms A and B is differentially regulated by estrogen in vivo.

Syvälä H, Vienonen A, Ylikomi T, Bläuer M, Zhuang YH, Tuohimaa P.

Biochem Biophys Res Commun. 1997 Feb 24;231(3):573-6.

PMID:
9070848
35.

Immunochemical and in situ hybridization analyses of retinoic acid receptor alpha, beta, and gamma in murine Harderian and submandibular glands.

Zhuang YH, Bläuer M, Pelto-Huikko M, Syvälä H, Tuohimaa P.

Histochem Cell Biol. 1996 Sep;106(3):311-8.

PMID:
8897072
36.

Hormone-dependent changes in A and B forms of progesterone receptor.

Syvälä H, Pekki A, Bläuer M, Pasanen S, Mäkinen E, Ylikomi T, Tuohimaa P.

J Steroid Biochem Mol Biol. 1996 Aug;58(5-6):517-24.

PMID:
8918977
37.

Androgen receptor in rat Harderian and submandibular glands.

Zhuang YH, Bläuer M, Syvälä H, Laine M, Tuohimaa P.

Histochem J. 1996 Jul;28(7):477-83.

PMID:
8872137
38.

Mechanisms of action of sex steroid hormones: basic concepts and clinical correlations.

Tuohimaa P, Bläuer M, Pasanen S, Passinen S, Pekki A, Punnonen R, Syvälä H, Valkila J, Wallén M, Väliaho J, Zhuang YH, Ylikomi T.

Maturitas. 1996 May;23 Suppl:S3-12. Review.

PMID:
8865132
39.

Progesterone receptor does not form oligomeric (8S), non-DNA-binding complex in intact cell nuclei.

Pekki A, Ylikomi T, Syvälä H, Tuohimaa P.

J Cell Biochem. 1995 May;58(1):95-104.

PMID:
7543904
40.

Progesterone receptor and hsp90 are not complexed in intact nuclei.

Pekki A, Ylikomi T, Syvälä H, Tuohimaa P.

J Steroid Biochem Mol Biol. 1994 Apr;48(5-6):475-9.

PMID:
8180108
41.

Immunohistochemical localization of the avian progesterone receptor and its candidate receptor binding factor (RBF-1).

Zhuang YH, Landers JP, Schuchard MD, Syvälä H, Gosse B, Ruesink T, Spelsberg TC, Tuohimaa P.

J Cell Biochem. 1993 Dec;53(4):383-93.

PMID:
8300755

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