Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 71

1.

Data on cytotoxic activity of an Artemisia annua herbal preparation and validation of the quantification method for active ingredient analysis.

Schmiech M, Lang SJ, Syrovets T, Simmet T.

Data Brief. 2019 Oct 15;27:104635. doi: 10.1016/j.dib.2019.104635. eCollection 2019 Dec.

2.

Comparative Investigation of Frankincense Nutraceuticals: Correlation of Boswellic and Lupeolic Acid Contents with Cytokine Release Inhibition and Toxicity against Triple-Negative Breast Cancer Cells.

Schmiech M, Lang SJ, Ulrich J, Werner K, Rashan LJ, Syrovets T, Simmet T.

Nutrients. 2019 Oct 2;11(10). pii: E2341. doi: 10.3390/nu11102341.

3.

Comparative Study on Hyaluronic Acid Binding to Murine SAA1.1 and SAA2.2.

Jin L, Syrovets T, Scheller JS, Zhang X, Simmet T.

ACS Omega. 2019 Aug 6;4(8):13388-13399. doi: 10.1021/acsomega.9b01590. eCollection 2019 Aug 20.

4.

A Novel Polyhalogenated Monoterpene Induces Cell Cycle Arrest and Apoptosis in Breast Cancer Cells.

El Gaafary M, Hafner S, Lang SJ, Jin L, Sabry OM, Vogel CV, Vanderwal CD, Syrovets T, Simmet T.

Mar Drugs. 2019 Jul 25;17(8). pii: E437. doi: 10.3390/md17080437.

5.

Ethosomes and lipid-coated chitosan nanocarriers for skin delivery of a chlorophyll derivative: A potential treatment of squamous cell carcinoma by photodynamic therapy.

Nasr S, Rady M, Gomaa I, Syrovets T, Simmet T, Fayad W, Abdel-Kader M.

Int J Pharm. 2019 Sep 10;568:118528. doi: 10.1016/j.ijpharm.2019.118528. Epub 2019 Jul 16.

PMID:
31323373
6.
7.

Antitumor activity of an Artemisia annua herbal preparation and identification of active ingredients.

Lang SJ, Schmiech M, Hafner S, Paetz C, Steinborn C, Huber R, Gaafary ME, Werner K, Schmidt CQ, Syrovets T, Simmet T.

Phytomedicine. 2019 Sep;62:152962. doi: 10.1016/j.phymed.2019.152962. Epub 2019 May 16.

8.

Boosting Antitumor Drug Efficacy with Chemically Engineered Multidomain Proteins.

Kuan SL, Fischer S, Hafner S, Wang T, Syrovets T, Liu W, Tokura Y, Ng DYW, Riegger A, Förtsch C, Jäger D, Barth TFE, Simmet T, Barth H, Weil T.

Adv Sci (Weinh). 2018 Jun 14;5(8):1701036. doi: 10.1002/advs.201701036. eCollection 2018 Aug.

9.

Spatiotemporal magnetic fields enhance cytosolic Ca2+ levels and induce actin polymerization via activation of voltage-gated sodium channels in skeletal muscle cells.

Rubio Ayala M, Syrovets T, Hafner S, Zablotskii V, Dejneka A, Simmet T.

Biomaterials. 2018 May;163:174-184. doi: 10.1016/j.biomaterials.2018.02.031. Epub 2018 Feb 16.

PMID:
29471128
10.

Acovenoside A Induces Mitotic Catastrophe Followed by Apoptosis in Non-Small-Cell Lung Cancer Cells.

El Gaafary M, Ezzat SM, El Sayed AM, Sabry OM, Hafner S, Lang S, Schmiech M, Syrovets T, Simmet T.

J Nat Prod. 2017 Dec 22;80(12):3203-3210. doi: 10.1021/acs.jnatprod.7b00546. Epub 2017 Nov 30.

PMID:
29190084
11.

Oleanolic acid methyl ester, a novel cytotoxic mitocan, induces cell cycle arrest and ROS-Mediated cell death in castration-resistant prostate cancer PC-3 cells.

Abdelmageed N, Morad SAF, Elghoneimy AA, Syrovets T, Simmet T, El-Zorba H, El-Banna HA, Cabot M, Abdel-Aziz MI.

Biomed Pharmacother. 2017 Dec;96:417-425. doi: 10.1016/j.biopha.2017.10.027. Epub 2017 Oct 12.

PMID:
29031200
12.

Acetyl-lupeolic acid inhibits Akt signaling and induces apoptosis in chemoresistant prostate cancer cells in vitro and in vivo.

Schmidt C, Loos C, Jin L, Schmiech M, Schmidt CQ, Gaafary ME, Syrovets T, Simmet T.

Oncotarget. 2017 Jul 8;8(33):55147-55161. doi: 10.18632/oncotarget.19101. eCollection 2017 Aug 15.

13.

Cellular mechanism of fibril formation from serum amyloid A1 protein.

Claus S, Meinhardt K, Aumüller T, Puscalau-Girtu I, Linder J, Haupt C, Walther P, Syrovets T, Simmet T, Fändrich M.

EMBO Rep. 2017 Aug;18(8):1352-1366. doi: 10.15252/embr.201643411. Epub 2017 Jun 21.

14.

The CAM cancer xenograft as a model for initial evaluation of MR labelled compounds.

Zuo Z, Syrovets T, Wu Y, Hafner S, Vernikouskaya I, Liu W, Ma G, Weil T, Simmet T, Rasche V.

Sci Rep. 2017 May 3;7:46690. doi: 10.1038/srep46690.

15.

Cell-to-cell transfer of SAA1 protein in a cell culture model of systemic AA amyloidosis.

Claus S, Puscalau-Girtu I, Walther P, Syrovets T, Simmet T, Haupt C, Fändrich M.

Sci Rep. 2017 Mar 31;7:45683. doi: 10.1038/srep45683.

16.

The Cardenolide Glycoside Acovenoside A Affords Protective Activity in Doxorubicin-Induced Cardiotoxicity in Mice.

Ezzat SM, El Gaafary M, El Sayed AM, Sabry OM, Ali ZY, Hafner S, Schmiech M, Jin L, Syrovets T, Simmet T.

J Pharmacol Exp Ther. 2016 Aug;358(2):262-70. doi: 10.1124/jpet.116.232652. Epub 2016 May 31. Erratum in: J Pharmacol Exp Ther. 2017 Jun;361(3):366.

PMID:
27247000
17.

Electron tomography reveals the fibril structure and lipid interactions in amyloid deposits.

Kollmer M, Meinhardt K, Haupt C, Liberta F, Wulff M, Linder J, Handl L, Heinrich L, Loos C, Schmidt M, Syrovets T, Simmet T, Westermark P, Westermark GT, Horn U, Schmidt V, Walther P, Fändrich M.

Proc Natl Acad Sci U S A. 2016 May 17;113(20):5604-9. doi: 10.1073/pnas.1523496113. Epub 2016 May 2.

18.

Carboxyl- and amino-functionalized polystyrene nanoparticles differentially affect the polarization profile of M1 and M2 macrophage subsets.

Fuchs AK, Syrovets T, Haas KA, Loos C, Musyanovych A, Mailänder V, Landfester K, Simmet T.

Biomaterials. 2016 Apr;85:78-87. doi: 10.1016/j.biomaterials.2016.01.064. Epub 2016 Jan 29.

PMID:
26854393
19.

Response to Letter Regarding Article, "Anti-inflammatory and Antiatherogenic Effects of the Inflammasome NLRP3 Inhibitor Arglabin in ApoE2.Ki Mice Fed a High-Fat Diet".

Abderrazak A, Couchie D, Darweesh Mahmood DF, Elhage R, Vindis C, Laffargue M, Matéo V, Büchele B, Ayala MR, Gaafary ME, Syrovets T, Slimane MN, Friguet B, Fulop T, Simmet T, Hadri KE, Rouis M.

Circulation. 2015 Nov 24;132(21):e250-1. doi: 10.1161/CIRCULATIONAHA.115.017739. No abstract available.

PMID:
26596983
20.

High-resolution MRI analysis of breast cancer xenograft on the chick chorioallantoic membrane.

Zuo Z, Syrovets T, Genze F, Abaei A, Ma G, Simmet T, Rasche V.

NMR Biomed. 2015 Apr;28(4):440-7. doi: 10.1002/nbm.3270. Epub 2015 Feb 25.

PMID:
25711154
21.

Functionalized polystyrene nanoparticles as a platform for studying bio-nano interactions.

Loos C, Syrovets T, Musyanovych A, Mailänder V, Landfester K, Nienhaus GU, Simmet T.

Beilstein J Nanotechnol. 2014 Dec 15;5:2403-12. doi: 10.3762/bjnano.5.250. eCollection 2014. Review.

22.

NLRP3 inflammasome: from a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases.

Abderrazak A, Syrovets T, Couchie D, El Hadri K, Friguet B, Simmet T, Rouis M.

Redox Biol. 2015;4:296-307. doi: 10.1016/j.redox.2015.01.008. Epub 2015 Jan 14. Review.

23.

Anti-inflammatory and antiatherogenic effects of the NLRP3 inflammasome inhibitor arglabin in ApoE2.Ki mice fed a high-fat diet.

Abderrazak A, Couchie D, Mahmood DF, Elhage R, Vindis C, Laffargue M, Matéo V, Büchele B, Ayala MR, El Gaafary M, Syrovets T, Slimane MN, Friguet B, Fulop T, Simmet T, El Hadri K, Rouis M.

Circulation. 2015 Mar 24;131(12):1061-70. doi: 10.1161/CIRCULATIONAHA.114.013730. Epub 2015 Jan 22.

PMID:
25613820
24.

An α-acetoxy-tirucallic acid isomer inhibits Akt/mTOR signaling and induces oxidative stress in prostate cancer cells.

El Gaafary M, Büchele B, Syrovets T, Agnolet S, Schneider B, Schmidt CQ, Simmet T.

J Pharmacol Exp Ther. 2015 Jan;352(1):33-42. doi: 10.1124/jpet.114.217323. Epub 2014 Oct 14.

PMID:
25316122
25.

Modulation of monocytic leukemia cell function and survival by high gradient magnetic fields and mathematical modeling studies.

Zablotskii V, Syrovets T, Schmidt ZW, Dejneka A, Simmet T.

Biomaterials. 2014 Mar;35(10):3164-71. doi: 10.1016/j.biomaterials.2013.12.098. Epub 2014 Jan 15.

PMID:
24439412
26.

Amino-functionalized nanoparticles as inhibitors of mTOR and inducers of cell cycle arrest in leukemia cells.

Loos C, Syrovets T, Musyanovych A, Mailänder V, Landfester K, Simmet T.

Biomaterials. 2014 Feb;35(6):1944-53. doi: 10.1016/j.biomaterials.2013.11.056. Epub 2013 Dec 9.

PMID:
24331713
27.

Estimation of half-life periods in nonlinear data with fractional polynomials.

Mayer B, Keller F, Syrovets T, Wittau M.

Stat Methods Med Res. 2016 Oct;25(5):1791-1803. Epub 2013 Sep 2.

PMID:
23999890
28.

WITHDRAWN: Static High-Gradient Magnetic Fields Activate Transient Receptor Potential Vanilloid 4 (TRPV4) Ion Channels Enabling Remote Control of Cell Function.

Lunov O, Zablotskii V, Syrovets T, Buechele B, Schmidt CQ, Dejneka A, Le Roy D, Dumas-Bouchiat F, Dempsey NM, Simmet T.

J Biol Chem. 2013 Jun 24. [Epub ahead of print]

29.

Recruitment of CCR6-expressing Th17 cells by CCL20 secreted from plasmin-stimulated macrophages.

Li Q, Laumonnier Y, Syrovets T, Simmet T.

Acta Biochim Biophys Sin (Shanghai). 2013 Jul;45(7):593-600. doi: 10.1093/abbs/gmt049. Epub 2013 May 16.

PMID:
23681234
30.

Plasmin induces intercellular adhesion molecule 1 expression in human endothelial cells via nuclear factor-κB/mitogen-activated protein kinases-dependent pathways.

Li Q, Syrovets T, Simmet T, Ding J, Xu J, Chen W, Zhu D, Gao P.

Exp Biol Med (Maywood). 2013 Feb;238(2):176-86. doi: 10.1177/1535370212473700.

PMID:
23576799
31.

Truncated thioredoxin (Trx-80) promotes pro-inflammatory macrophages of the M1 phenotype and enhances atherosclerosis.

Mahmood DF, Abderrazak A, Couchie D, Lunov O, Diderot V, Syrovets T, Slimane MN, Gosselet F, Simmet T, Rouis M, El Hadri K.

J Cell Physiol. 2013 Jul;228(7):1577-83. doi: 10.1002/jcp.24319.

PMID:
23335265
32.

A novel semisynthetic inhibitor of the FRB domain of mammalian target of rapamycin blocks proliferation and triggers apoptosis in chemoresistant prostate cancer cells.

Morad SA, Schmid M, Büchele B, Siehl HU, El Gafaary M, Lunov O, Syrovets T, Simmet T.

Mol Pharmacol. 2013 Feb;83(2):531-41. doi: 10.1124/mol.112.081349. Epub 2012 Dec 3.

PMID:
23208958
33.

The serine protease plasmin triggers expression of the CC-chemokine ligand 20 in dendritic cells via Akt/NF-κB-dependent pathways.

Li X, Syrovets T, Simmet T.

J Biomed Biotechnol. 2012;2012:186710. doi: 10.1155/2012/186710. Epub 2012 Oct 14.

34.

Plasmin as a proinflammatory cell activator.

Syrovets T, Lunov O, Simmet T.

J Leukoc Biol. 2012 Sep;92(3):509-19. doi: 10.1189/jlb.0212056. Epub 2012 May 4. Review.

PMID:
22561604
35.

Thioredoxin-1 promotes anti-inflammatory macrophages of the M2 phenotype and antagonizes atherosclerosis.

El Hadri K, Mahmood DF, Couchie D, Jguirim-Souissi I, Genze F, Diderot V, Syrovets T, Lunov O, Simmet T, Rouis M.

Arterioscler Thromb Vasc Biol. 2012 Jun;32(6):1445-52. doi: 10.1161/ATVBAHA.112.249334. Epub 2012 Apr 19.

PMID:
22516068
36.

Human cytomegalovirus infection and atherothrombosis.

Popović M, Smiljanić K, Dobutović B, Syrovets T, Simmet T, Isenović ER.

J Thromb Thrombolysis. 2012 Feb;33(2):160-72. doi: 10.1007/s11239-011-0662-x. Review.

PMID:
22161772
37.

Amino-functionalized polystyrene nanoparticles activate the NLRP3 inflammasome in human macrophages.

Lunov O, Syrovets T, Loos C, Nienhaus GU, Mailänder V, Landfester K, Rouis M, Simmet T.

ACS Nano. 2011 Dec 27;5(12):9648-57. doi: 10.1021/nn203596e. Epub 2011 Dec 8.

PMID:
22111911
38.

Yeast two-hybrid screening of proteins interacting with plasmin receptor subunit: C-terminal fragment of annexin A2.

Li Q, Laumonnier Y, Syrovets T, Simmet T.

Acta Pharmacol Sin. 2011 Nov;32(11):1411-8. doi: 10.1038/aps.2011.121. Epub 2011 Oct 3.

39.

Thrombin and vascular inflammation.

Popović M, Smiljanić K, Dobutović B, Syrovets T, Simmet T, Isenović ER.

Mol Cell Biochem. 2012 Jan;359(1-2):301-13. doi: 10.1007/s11010-011-1024-x. Epub 2011 Aug 23. Review.

PMID:
21858738
40.

(8R)-3β,8-dihydroxypolypoda-13E,17E,21-triene induces cell cycle arrest and apoptosis in treatment-resistant prostate cancer cells.

Morad SA, Schmidt C, Büchele B, Schneider B, Wenzler M, Syrovets T, Simmet T.

J Nat Prod. 2011 Aug 26;74(8):1731-6. doi: 10.1021/np200161a. Epub 2011 Jul 29.

PMID:
21800858
41.

Peroxisome proliferator-activated receptor gamma induces apoptosis and inhibits autophagy of human monocyte-derived macrophages via induction of cathepsin L: potential role in atherosclerosis.

Mahmood DF, Jguirim-Souissi I, Khadija el-H, Blondeau N, Diderot V, Amrani S, Slimane MN, Syrovets T, Simmet T, Rouis M.

J Biol Chem. 2011 Aug 19;286(33):28858-66. doi: 10.1074/jbc.M111.273292. Epub 2011 Jun 23.

42.

Variability in transport and biotransformation of cytarabine is associated with its toxicity in peripheral blood mononuclear cells.

Parmar S, Seeringer A, Denich D, Gärtner F, Pitterle K, Syrovets T, Ohmle B, Stingl JC.

Pharmacogenomics. 2011 Apr;12(4):503-14. doi: 10.2217/pgs.10.200.

PMID:
21521023
43.

Differential uptake of functionalized polystyrene nanoparticles by human macrophages and a monocytic cell line.

Lunov O, Syrovets T, Loos C, Beil J, Delacher M, Tron K, Nienhaus GU, Musyanovych A, Mailänder V, Landfester K, Simmet T.

ACS Nano. 2011 Mar 22;5(3):1657-69. doi: 10.1021/nn2000756. Epub 2011 Feb 23.

PMID:
21344890
44.

Modeling receptor-mediated endocytosis of polymer-functionalized iron oxide nanoparticles by human macrophages.

Lunov O, Zablotskii V, Syrovets T, Röcker C, Tron K, Nienhaus GU, Simmet T.

Biomaterials. 2011 Jan;32(2):547-55. doi: 10.1016/j.biomaterials.2010.08.111. Epub 2010 Sep 28.

PMID:
20880574
45.

Lysosomal degradation of the carboxydextran shell of coated superparamagnetic iron oxide nanoparticles and the fate of professional phagocytes.

Lunov O, Syrovets T, Röcker C, Tron K, Nienhaus GU, Rasche V, Mailänder V, Landfester K, Simmet T.

Biomaterials. 2010 Dec;31(34):9015-22. doi: 10.1016/j.biomaterials.2010.08.003. Epub 2010 Aug 23.

PMID:
20739059
46.

A role for the annexin A2 amino-terminal peptide in the plasmin-induced activation of human peripheral monocytes.

Li Q, Ke F, Zhang W, Laumonnier Y, Syrovets T, Simmet T, Wang H.

Mol Immunol. 2010 Aug;47(14):2405-10. doi: 10.1016/j.molimm.2010.03.015. Epub 2010 Jun 2. Retraction in: Mol Immunol. 2011 Dec;49(3):566.

PMID:
20627396
47.

The effect of carboxydextran-coated superparamagnetic iron oxide nanoparticles on c-Jun N-terminal kinase-mediated apoptosis in human macrophages.

Lunov O, Syrovets T, Büchele B, Jiang X, Röcker C, Tron K, Nienhaus GU, Walther P, Mailänder V, Landfester K, Simmet T.

Biomaterials. 2010 Jul;31(19):5063-71. doi: 10.1016/j.biomaterials.2010.03.023. Epub 2010 Apr 9.

PMID:
20381862
48.

Surface plasmon resonance analysis of nuclear factor-kappaB protein interactions with the sesquiterpene lactone helenalin.

Büchele B, Zugmaier W, Lunov O, Syrovets T, Merfort I, Simmet T.

Anal Biochem. 2010 Jun 1;401(1):30-7. doi: 10.1016/j.ab.2010.02.020. Epub 2010 Feb 20.

PMID:
20175984
49.

Plasmin triggers chemotaxis of monocyte-derived dendritic cells through an Akt2-dependent pathway and promotes a T-helper type-1 response.

Li X, Syrovets T, Genze F, Pitterle K, Oberhuber A, Orend KH, Simmet T.

Arterioscler Thromb Vasc Biol. 2010 Mar;30(3):582-90. doi: 10.1161/ATVBAHA.109.202044. Epub 2010 Jan 7.

PMID:
20056908
50.

Tirucallic acids are novel pleckstrin homology domain-dependent Akt inhibitors inducing apoptosis in prostate cancer cells.

Estrada AC, Syrovets T, Pitterle K, Lunov O, Büchele B, Schimana-Pfeifer J, Schmidt T, Morad SA, Simmet T.

Mol Pharmacol. 2010 Mar;77(3):378-87. doi: 10.1124/mol.109.060475. Epub 2009 Dec 16.

PMID:
20018812

Supplemental Content

Loading ...
Support Center