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Items: 1 to 50 of 77


Assessing Statewide All-Cause Future One-Year Mortality: Prospective Study With Implications for Quality of Life, Resource Utilization, and Medical Futility.

Guo Y, Zheng G, Fu T, Hao S, Ye C, Zheng L, Liu M, Xia M, Jin B, Zhu C, Wang O, Wu Q, Culver DS, Alfreds ST, Stearns F, Kanov L, Bhatia A, Sylvester KG, Widen E, McElhinney DB, Ling XB.

J Med Internet Res. 2018 Jun 4;20(6):e10311. doi: 10.2196/10311.


Prediction of Incident Hypertension Within the Next Year: Prospective Study Using Statewide Electronic Health Records and Machine Learning.

Ye C, Fu T, Hao S, Zhang Y, Wang O, Jin B, Xia M, Liu M, Zhou X, Wu Q, Guo Y, Zhu C, Li YM, Culver DS, Alfreds ST, Stearns F, Sylvester KG, Widen E, McElhinney D, Ling X.

J Med Internet Res. 2018 Jan 30;20(1):e22. doi: 10.2196/jmir.9268.


Development of the necrotizing enterocolitis society registry and biorepository.

Ralls MW, Gadepalli SK, Sylvester KG, Good M.

Semin Pediatr Surg. 2018 Feb;27(1):25-28. doi: 10.1053/j.sempedsurg.2017.11.005. Epub 2017 Nov 6.


The Effect of Level of Care on Gastroschisis Outcomes.

Apfeld JC, Kastenberg ZJ, Sylvester KG, Lee HC.

J Pediatr. 2017 Nov;190:79-84.e1. doi: 10.1016/j.jpeds.2017.07.008.


Heme Oxygenase Activity and Heme Binding in a Neonatal Mouse Model.

Kourula S, Ang J, Zhao H, Kalish F, Vandenabeele P, Sylvester KG, Wong RJ, Stevenson DK.

Neonatology. 2017;112(4):376-383. doi: 10.1159/000479493. Epub 2017 Sep 20.


Estimating One-Year Risk of Incident Chronic Kidney Disease: Retrospective Development and Validation Study Using Electronic Medical Record Data From the State of Maine.

Hao S, Fu T, Wu Q, Jin B, Zhu C, Hu Z, Guo Y, Zhang Y, Yu Y, Fouts T, Ng P, Culver DS, Alfreds ST, Stearns F, Sylvester KG, Widen E, McElhinney DB, Ling XB.

JMIR Med Inform. 2017 Jul 26;5(3):e21. doi: 10.2196/medinform.7954.


Defining and characterizing the critical transition state prior to the type 2 diabetes disease.

Jin B, Liu R, Hao S, Li Z, Zhu C, Zhou X, Chen P, Fu T, Hu Z, Wu Q, Liu W, Liu D, Yu Y, Zhang Y, McElhinney DB, Li YM, Culver DS, Alfreds ST, Stearns F, Sylvester KG, Widen E, Ling XB.

PLoS One. 2017 Jul 7;12(7):e0180937. doi: 10.1371/journal.pone.0180937. eCollection 2017.


FAM83H is involved in the progression of hepatocellular carcinoma and is regulated by MYC.

Kim KM, Park SH, Bae JS, Noh SJ, Tao GZ, Kim JR, Kwon KS, Park HS, Park BH, Lee H, Chung MJ, Moon WS, Sylvester KG, Jang KY.

Sci Rep. 2017 Jun 12;7(1):3274. doi: 10.1038/s41598-017-03639-3.


Advanced minimal access surgery in infants weighing less than 3kg: A single center experience.

Wall JK, Sinclair TJ, Kethman W, Williams C, Albanese C, Sylvester KG, Bruzoni M.

J Pediatr Surg. 2018 Mar;53(3):503-507. doi: 10.1016/j.jpedsurg.2017.05.006. Epub 2017 May 11.


Involvement of prolyl isomerase PIN1 in the cell cycle progression and proliferation of hepatic oval cells.

Risal P, Shrestha N, Chand L, Sylvester KG, Jeong YJ.

Pathol Res Pract. 2017 Apr;213(4):373-380. doi: 10.1016/j.prp.2017.01.005. Epub 2017 Jan 18.


Prediction of neonatal respiratory distress in pregnancies complicated by fetal lung masses.

Girsen AI, Hintz SR, Sammour R, Naqvi A, El-Sayed YY, Sherwin K, Davis AS, Chock VY, Barth RA, Rubesova E, Sylvester KG, Chitkara R, Blumenfeld YJ.

Prenat Diagn. 2017 Mar;37(3):266-272. doi: 10.1002/pd.5002. Epub 2017 Feb 17.


Unique Molecular Patterns Uncovered in Kawasaki Disease Patients with Elevated Serum Gamma Glutamyl Transferase Levels: Implications for Intravenous Immunoglobulin Responsiveness.

Wang Y, Li Z, Hu G, Hao S, Deng X, Huang M, Ren M, Jiang X, Kanegaye JT, Ha KS, Lee J, Li X, Jiang X, Yu Y, Tremoulet AH, Burns JC, Whitin JC, Shin AY, Sylvester KG, McElhinney DB, Cohen HJ, Ling XB; Pediatric Emergency Medicine Kawasaki Disease Research Group.

PLoS One. 2016 Dec 21;11(12):e0167434. doi: 10.1371/journal.pone.0167434. eCollection 2016.


Web-based Real-Time Case Finding for the Population Health Management of Patients With Diabetes Mellitus: A Prospective Validation of the Natural Language Processing-Based Algorithm With Statewide Electronic Medical Records.

Zheng L, Wang Y, Hao S, Shin AY, Jin B, Ngo AD, Jackson-Browne MS, Feller DJ, Fu T, Zhang K, Zhou X, Zhu C, Dai D, Yu Y, Zheng G, Li YM, McElhinney DB, Culver DS, Alfreds ST, Stearns F, Sylvester KG, Widen E, Ling XB.

JMIR Med Inform. 2016 Nov 11;4(4):e37.


Acylcarnitine Profiles Reflect Metabolic Vulnerability for Necrotizing Enterocolitis in Newborns Born Premature.

Sylvester KG, Kastenberg ZJ, Moss RL, Enns GM, Cowan TM, Shaw GM, Stevenson DK, Sinclair TJ, Scharfe C, Ryckman KK, Jelliffe-Pawlowski LL.

J Pediatr. 2017 Feb;181:80-85.e1. doi: 10.1016/j.jpeds.2016.10.019. Epub 2016 Nov 8.


Mapping the Fetomaternal Peripheral Immune System at Term Pregnancy.

Fragiadakis GK, Baca QJ, Gherardini PF, Ganio EA, Gaudilliere DK, Tingle M, Lancero HL, McNeil LS, Spitzer MH, Wong RJ, Shaw GM, Darmstadt GL, Sylvester KG, Winn VD, Carvalho B, Lewis DB, Stevenson DK, Nolan GP, Aghaeepour N, Angst MS, Gaudilliere BL.

J Immunol. 2016 Dec 1;197(11):4482-4492. Epub 2016 Oct 28.


CK2α/CSNK2A1 Phosphorylates SIRT6 and Is Involved in the Progression of Breast Carcinoma and Predicts Shorter Survival of Diagnosed Patients.

Bae JS, Park SH, Jamiyandorj U, Kim KM, Noh SJ, Kim JR, Park HJ, Kwon KS, Jung SH, Park HS, Park BH, Lee H, Moon WS, Sylvester KG, Jang KY.

Am J Pathol. 2016 Dec;186(12):3297-3315. doi: 10.1016/j.ajpath.2016.08.007. Epub 2016 Oct 13.


HDlive imaging of a giant omphalocele.

Blumenfeld YJ, E Milan K, Rubesova E, Sylvester KG, Davis AS, Chock VY, Hintz SR.

Ultrasound Obstet Gynecol. 2016 Sep;48(3):407-8. doi: 10.1002/uog.15993. No abstract available.


Prospective stratification of patients at risk for emergency department revisit: resource utilization and population management strategy implications.

Jin B, Zhao Y, Hao S, Shin AY, Wang Y, Zhu C, Hu Z, Fu C, Ji J, Wang Y, Zhao Y, Jiang Y, Dai D, Culver DS, Alfreds ST, Rogow T, Stearns F, Sylvester KG, Widen E, Ling XB.

BMC Emerg Med. 2016 Feb 3;16:10. doi: 10.1186/s12873-016-0074-5.


Pilot Application of Magnetic Nanoparticle-Based Biosensor for Necrotizing Enterocolitis.

Kim D, Fu C, Ling XB, Hu Z, Tao G, Zhao Y, Kastenberg ZJ, Sylvester KG, Wang SX.

J Proteomics Bioinform. 2015;Suppl 5. pii: 002. doi: 10.4172/jpb.S5-002. Epub 2013 Dec 18.


Development, Validation and Deployment of a Real Time 30 Day Hospital Readmission Risk Assessment Tool in the Maine Healthcare Information Exchange.

Hao S, Wang Y, Jin B, Shin AY, Zhu C, Huang M, Zheng L, Luo J, Hu Z, Fu C, Dai D, Wang Y, Culver DS, Alfreds ST, Rogow T, Stearns F, Sylvester KG, Widen E, Ling XB.

PLoS One. 2015 Oct 8;10(10):e0140271. doi: 10.1371/journal.pone.0140271. eCollection 2015.


Serological targeted analysis of an ITIH4 peptide isoform: a preterm birth biomarker and its associated SNP implications.

Tan Z, Hu Z, Cai EY, Alev C, Yang T, Li Z, Sung J, El-Sayed YY, Shaw GM, Stevenson DK, Butte AJ, Sheng G, Sylvester KG, Cohen HJ, Ling XB.

J Genet Genomics. 2015 Sep 20;42(9):507-10. doi: 10.1016/j.jgg.2015.06.001. Epub 2015 Jun 14. No abstract available.


Online Prediction of Health Care Utilization in the Next Six Months Based on Electronic Health Record Information: A Cohort and Validation Study.

Hu Z, Hao S, Jin B, Shin AY, Zhu C, Huang M, Wang Y, Zheng L, Dai D, Culver DS, Alfreds ST, Rogow T, Stearns F, Sylvester KG, Widen E, Ling X.

J Med Internet Res. 2015 Sep 22;17(9):e219. doi: 10.2196/jmir.4976.


Augmented Wnt signaling as a therapeutic tool to prevent ischemia/reperfusion injury in liver: Preclinical studies in a mouse model.

Liu B, Zhang R, Tao G, Lehwald NC, Liu B, Koh Y, Sylvester KG.

Liver Transpl. 2015 Dec;21(12):1533-42. doi: 10.1002/lt.24331.


Role of the Wnt/β-Catenin Pathway in the Pathogenesis of Alcoholic Liver Disease.

Behari J, Sylvester KG.

Curr Mol Pharmacol. 2017;10(3):186-194. doi: 10.2174/1874467208666150817111256.


Impaired Activity of Blood Coagulant Factor XIII in Patients with Necrotizing Enterocolitis.

Tao GZ, Liu B, Zhang R, Liu G, Abdullah F, Harris MC, Brandt ML, Ehrenkranz RA, Bowers C, Martin CR, Moss RL, Sylvester KG.

Sci Rep. 2015 Aug 17;5:13119. doi: 10.1038/srep13119.


NLP based congestive heart failure case finding: A prospective analysis on statewide electronic medical records.

Wang Y, Luo J, Hao S, Xu H, Shin AY, Jin B, Liu R, Deng X, Wang L, Zheng L, Zhao Y, Zhu C, Hu Z, Fu C, Hao Y, Zhao Y, Jiang Y, Dai D, Culver DS, Alfreds ST, Todd R, Stearns F, Sylvester KG, Widen E, Ling XB.

Int J Med Inform. 2015 Dec;84(12):1039-47. doi: 10.1016/j.ijmedinf.2015.06.007. Epub 2015 Jul 2.


Infant, maternal, and geographic factors influencing gastroschisis related mortality in Zimbabwe.

Apfeld JC, Wren SM, Macheka N, Mbuwayesango BA, Bruzoni M, Sylvester KG, Kastenberg ZJ.

Surgery. 2015 Dec;158(6):1475-80. doi: 10.1016/j.surg.2015.04.037. Epub 2015 Jun 11.


Urine biomarkers for necrotizing enterocolitis.

Sylvester KG, Moss RL.

Pediatr Surg Int. 2015 May;31(5):421-9. doi: 10.1007/s00383-015-3693-0. Epub 2015 Mar 26. Review.


Real-time web-based assessment of total population risk of future emergency department utilization: statewide prospective active case finding study.

Hu Z, Jin B, Shin AY, Zhu C, Zhao Y, Hao S, Zheng L, Fu C, Wen Q, Ji J, Li Z, Wang Y, Zheng X, Dai D, Culver DS, Alfreds ST, Rogow T, Stearns F, Sylvester KG, Widen E, Ling XB.

Interact J Med Res. 2015 Jan 13;4(1):e2. doi: 10.2196/ijmr.4022.


Risk prediction of emergency department revisit 30 days post discharge: a prospective study.

Hao S, Jin B, Shin AY, Zhao Y, Zhu C, Li Z, Hu Z, Fu C, Ji J, Wang Y, Zhao Y, Dai D, Culver DS, Alfreds ST, Rogow T, Stearns F, Sylvester KG, Widen E, Ling XB.

PLoS One. 2014 Nov 13;9(11):e112944. doi: 10.1371/journal.pone.0112944. eCollection 2014. Erratum in: PLoS One. 2015;10(1):e0117633.


Effect of deregionalized care on mortality in very low-birth-weight infants with necrotizing enterocolitis.

Kastenberg ZJ, Lee HC, Profit J, Gould JB, Sylvester KG.

JAMA Pediatr. 2015 Jan;169(1):26-32. doi: 10.1001/jamapediatrics.2014.2085.


Hippo/YAP, β-catenin, and the cancer cell: a "ménage à trois" in hepatoblastoma.

Sylvester KG, Colnot S.

Gastroenterology. 2014 Sep;147(3):562-5. doi: 10.1053/j.gastro.2014.07.026. Epub 2014 Jul 27. No abstract available.


CK2α phosphorylates DBC1 and is involved in the progression of gastric carcinoma and predicts poor survival of gastric carcinoma patients.

Bae JS, Park SH, Kim KM, Kwon KS, Kim CY, Lee HK, Park BH, Park HS, Lee H, Moon WS, Chung MJ, Sylvester KG, Jang KY.

Int J Cancer. 2015 Feb 15;136(4):797-809. doi: 10.1002/ijc.29043. Epub 2014 Jul 1.


A data-driven algorithm integrating clinical and laboratory features for the diagnosis and prognosis of necrotizing enterocolitis.

Ji J, Ling XB, Zhao Y, Hu Z, Zheng X, Xu Z, Wen Q, Kastenberg ZJ, Li P, Abdullah F, Brandt ML, Ehrenkranz RA, Harris MC, Lee TC, Simpson BJ, Bowers C, Moss RL, Sylvester KG.

PLoS One. 2014 Feb 28;9(2):e89860. doi: 10.1371/journal.pone.0089860. eCollection 2014.


Urine protein biomarkers for the diagnosis and prognosis of necrotizing enterocolitis in infants.

Sylvester KG, Ling XB, Liu GY, Kastenberg ZJ, Ji J, Hu Z, Wu S, Peng S, Abdullah F, Brandt ML, Ehrenkranz RA, Harris MC, Lee TC, Simpson BJ, Bowers C, Moss RL.

J Pediatr. 2014 Mar;164(3):607-12.e1-7. doi: 10.1016/j.jpeds.2013.10.091. Epub 2014 Jan 14.


A novel urine peptide biomarker-based algorithm for the prognosis of necrotising enterocolitis in human infants.

Sylvester KG, Ling XB, Liu GY, Kastenberg ZJ, Ji J, Hu Z, Peng S, Lau K, Abdullah F, Brandt ML, Ehrenkranz RA, Harris MC, Lee TC, Simpson J, Bowers C, Moss RL.

Gut. 2014 Aug;63(8):1284-92. doi: 10.1136/gutjnl-2013-305130. Epub 2013 Sep 18.


Wnt/β-catenin signaling protects mouse liver against oxidative stress-induced apoptosis through the inhibition of forkhead transcription factor FoxO3.

Tao GZ, Lehwald N, Jang KY, Baek J, Xu B, Omary MB, Sylvester KG.

J Biol Chem. 2013 Jun 14;288(24):17214-24. doi: 10.1074/jbc.M112.445965. Epub 2013 Apr 25.


Heme oxygenase-1 deficiency promotes the development of necrotizing enterocolitis-like intestinal injury in a newborn mouse model.

Schulz S, Wong RJ, Jang KY, Kalish F, Chisholm KM, Zhao H, Vreman HJ, Sylvester KG, Stevenson DK.

Am J Physiol Gastrointest Liver Physiol. 2013 Jun 1;304(11):G991-G1001. doi: 10.1152/ajpgi.00363.2012. Epub 2013 Apr 11.


The surgical management of necrotizing enterocolitis.

Kastenberg ZJ, Sylvester KG.

Clin Perinatol. 2013 Mar;40(1):135-48. doi: 10.1016/j.clp.2012.12.011. Epub 2013 Jan 17. Review.


SIRT1 and c-Myc promote liver tumor cell survival and predict poor survival of human hepatocellular carcinomas.

Jang KY, Noh SJ, Lehwald N, Tao GZ, Bellovin DI, Park HS, Moon WS, Felsher DW, Sylvester KG.

PLoS One. 2012;7(9):e45119. Epub 2012 Sep 14.


β-Catenin regulates hepatic mitochondrial function and energy balance in mice.

Lehwald N, Tao GZ, Jang KY, Papandreou I, Liu B, Liu B, Pysz MA, Willmann JK, Knoefel WT, Denko NC, Sylvester KG.

Gastroenterology. 2012 Sep;143(3):754-764. doi: 10.1053/j.gastro.2012.05.048. Epub 2012 Jun 7.


Effect of alpha-naphthylisothiocyanate-induced liver injury on intestinal adaptation in a rat model of short bowel syndrome.

Sukhotnik I, Razon H, Pollak Y, Hayari L, Bejar J, Mogilner JG, Sylvester KG.

Pediatr Surg Int. 2012 Feb;28(2):161-9. doi: 10.1007/s00383-011-2989-y.


Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway.

Viatour P, Ehmer U, Saddic LA, Dorrell C, Andersen JB, Lin C, Zmoos AF, Mazur PK, Schaffer BE, Ostermeier A, Vogel H, Sylvester KG, Thorgeirsson SS, Grompe M, Sage J.

J Exp Med. 2011 Sep 26;208(10):1963-76. doi: 10.1084/jem.20110198. Epub 2011 Aug 29.


Intestinal involvement during 3,5-diethoxycarbonyl-1,4-dihydrocollidine-induced chronic liver injury in a mouse model.

Sukhotnik I, Kuscuoglu U, Altindag B, Tao GZ, Lehwald N, Sylvester KG.

J Pediatr Surg. 2011 Aug;46(8):1495-502. doi: 10.1016/j.jpedsurg.2011.04.007.


The establishment and characterization of immortal hepatocyte cell lines from a mouse liver injury model.

Risal P, Cho BH, Sylvester KG, Kim JC, Kim HT, Jeong YJ.

In Vitro Cell Dev Biol Anim. 2011 Sep;47(8):526-34. doi: 10.1007/s11626-011-9445-0. Epub 2011 Jul 30.


Chylous ascites after laparoscopic Nissen fundoplication.

Park KT, Adikibi B, MacKinlay GA, Gillett PM, Sylvester KG, Kerner JA.

Dig Dis Sci. 2012 Jan;57(1):28-31. doi: 10.1007/s10620-011-1808-6. Epub 2011 Jul 7. No abstract available.


Wnt-β-catenin signaling protects against hepatic ischemia and reperfusion injury in mice.

Lehwald N, Tao GZ, Jang KY, Sorkin M, Knoefel WT, Sylvester KG.

Gastroenterology. 2011 Aug;141(2):707-18, 718.e1-5. doi: 10.1053/j.gastro.2011.04.051. Epub 2011 May 4.


Risk factors for parenteral nutrition–associated liver disease following surgical therapy for necrotizing enterocolitis: A Glaser Pediatric Research Network Study [corrected].

Duro D, Mitchell PD, Kalish LA, Martin C, McCarthy M, Jaksic T, Dunn J, Brandt ML, Nobuhara KK, Sylvester KG, Moss RL, Duggan C.

J Pediatr Gastroenterol Nutr. 2011 May;52(5):595-600. doi: 10.1097/MPG.0b013e31820e8396. Erratum in: J Pediatr Gastroenterol Nutr. 2011 Nov;53(5):583.


Urine peptidomics for clinical biomarker discovery.

Ling XB, Mellins ED, Sylvester KG, Cohen HJ.

Adv Clin Chem. 2010;51:181-213. Review.


Risk factors for intestinal failure in infants with necrotizing enterocolitis: a Glaser Pediatric Research Network study.

Duro D, Kalish LA, Johnston P, Jaksic T, McCarthy M, Martin C, Dunn JC, Brandt M, Nobuhara KK, Sylvester KG, Moss RL, Duggan C.

J Pediatr. 2010 Aug;157(2):203-208.e1. doi: 10.1016/j.jpeds.2010.02.023. Epub 2010 May 6.

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