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Vav1-mediated scaffolding interactions stabilize SLP-76 microclusters and contribute to antigen-dependent T cell responses.

Sylvain NR, Nguyen K, Bunnell SC.

Sci Signal. 2011 Mar 8;4(163):ra14. doi: 10.1126/scisignal.2001178.


T cell costimulation via the integrin VLA-4 inhibits the actin-dependent centralization of signaling microclusters containing the adaptor SLP-76.

Nguyen K, Sylvain NR, Bunnell SC.

Immunity. 2008 Jun;28(6):810-21. doi: 10.1016/j.immuni.2008.04.019.

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