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Items: 1 to 50 of 262

1.

Proton detection of carbon-carbon couplings in symmetrical molecules: Analytical explanation, SYMONA pulse sequence.

Blechta V, Sýkora J.

J Magn Reson. 2019 Jan;298:107-114. doi: 10.1016/j.jmr.2018.12.002. Epub 2018 Dec 5.

PMID:
30544014
2.

Helicene-SPP Based Chiral Plasmonic Hybrid Structure: Toward Direct Enantiomers SERS Discrimination.

Kalachyova Y, Guselnikova O, Elashnikov R, Panov I, Žádný J, Cirkva V, Storch J, Sykora J, Záruba K, Švorčík V, Lyutakov O.

ACS Appl Mater Interfaces. 2018 Dec 7. doi: 10.1021/acsami.8b15520. [Epub ahead of print]

PMID:
30525385
3.

Molecular Gating of an Engineered Enzyme Captured in Real Time.

Kokkonen P, Sykora J, Prokop Z, Ghose A, Bednar D, Amaro M, Beerens K, Bidmanova S, Slanska M, Brezovsky J, Damborsky J, Hof M.

J Am Chem Soc. 2018 Dec 3. doi: 10.1021/jacs.8b09848. [Epub ahead of print]

PMID:
30501200
4.

Roughness of Transmembrane Helices Reduces Lipid Membrane Dynamics.

Olšinová M, Jurkiewicz P, Kishko I, Sýkora J, Sabó J, Hof M, Cwiklik L, Cebecauer M.

iScience. 2018 Dec 21;10:87-97. doi: 10.1016/j.isci.2018.11.026. Epub 2018 Nov 20.

5.

The use of styrene-maleic acid copolymer (SMA) for studies on T cell membrane rafts.

Angelisová P, Ballek O, Sýkora J, Benada O, Čajka T, Pokorná J, Pinkas D, Hořejší V.

Biochim Biophys Acta Biomembr. 2019 Jan;1861(1):130-141. doi: 10.1016/j.bbamem.2018.08.006. Epub 2018 Aug 14.

PMID:
30463696
6.

Late diagnosis of complete androgen insensitivity syndrome and transmission/carriers of the disease in a family with mutation c.2495G>T p.(Arg832Leu) in exon 7 of the androgen receptor gene: genetic, clinical and ethical aspects.

Pomahacova R, Zamboryova J, Paterova P, Krepelova A, Subrt I, Jaklova R, Vohradska P, Hrdonkova E, Sykora J.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2018 Nov 6. doi: 10.5507/bp.2018.067. [Epub ahead of print]

PMID:
30401990
7.

Significant benefits of new communication technology for time delay management in STEMI patients.

Studencan M, Alusik D, Plachy L, Bajerovska L, Ilavsky M, Karas J, Kilianova A, Sykora J, Hosa V, Kmec J, Slanina M, Boguska D.

PLoS One. 2018 Nov 2;13(11):e0205832. doi: 10.1371/journal.pone.0205832. eCollection 2018.

8.

A Single-Chain-Based Hexavalent CD27 Agonist Enhances T Cell Activation and Induces Anti-Tumor Immunity.

Thiemann M, Richards DM, Heinonen K, Kluge M, Marschall V, Merz C, Redondo Müller M, Schnyder T, Sefrin JP, Sykora J, Fricke H, Gieffers C, Hill O.

Front Oncol. 2018 Sep 19;8:387. doi: 10.3389/fonc.2018.00387. eCollection 2018.

9.

The Hexavalent CD40 Agonist HERA-CD40L Induces T-Cell-mediated Antitumor Immune Response Through Activation of Antigen-presenting Cells.

Merz C, Sykora J, Marschall V, Richards DM, Heinonen K, Redondo Müller M, Thiemann M, Schnyder T, Fricke H, Hill O, Gieffers C.

J Immunother. 2018 Nov/Dec;41(9):385-398. doi: 10.1097/CJI.0000000000000246.

PMID:
30273198
10.

Diagnosis of pancreatic cancer via1H NMR metabolomics of human plasma.

Michálková L, Horník Š, Sýkora J, Habartová L, Setnička V.

Analyst. 2018 Dec 3;143(24):5974-5978. doi: 10.1039/c8an01310a.

PMID:
30270368
11.

Plethysmographic and biochemical markers in the diagnosis of endothelial dysfunction in pediatric acute lymphoblastic leukemia survivors - new applications.

Masopustová A, Jehlička P, Huml M, Votava T, Trefil L, Kreslová M, Sýkora J.

Physiol Res. 2018 Dec 18;67(6):903-909. Epub 2018 Sep 11.

12.

Current global trends in the incidence of pediatric-onset inflammatory bowel disease.

Sýkora J, Pomahačová R, Kreslová M, Cvalínová D, Štych P, Schwarz J.

World J Gastroenterol. 2018 Jul 7;24(25):2741-2763. doi: 10.3748/wjg.v24.i25.2741. Review.

13.

Autoimmune disease, familial clustering and thyroid carcinoma coexistent with autoimmune thyroiditis in children and adolescence: A cross-sectional study from the Czech Republic.

Pomahacova R, Zamboryova J, Paterova P, Fiklik K, Cerna Z, Lad V, Skalicka E, Huml M, Sykora J.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2018 Jun 7. doi: 10.5507/bp.2018.030. [Epub ahead of print]

PMID:
29936527
14.

Monitoring of nucleophosmin oligomerization in live cells.

Holoubek A, Herman P, Sýkora J, Brodská B, Humpolíčková J, Kráčmarová M, Gášková D, Hof M, Kuželová K.

Methods Appl Fluoresc. 2018 Jun 29;6(3):035016. doi: 10.1088/2050-6120/aaccb9.

PMID:
29901450
15.

Xanthones Content in Swertia multicaulis D. Don from Nepal.

Timsina B, Kindlmann P, Rokaya MB, Vrchotová N, Tříska J, Horník Š, Sýkora J.

Molecules. 2018 May 3;23(5). pii: E1067. doi: 10.3390/molecules23051067.

16.

2-Bromo[6]helicene as a Key Intermediate for [6]Helicene Functionalization.

Jakubec M, Beránek T, Jakubík P, Sýkora J, Žádný J, Církva V, Storch J.

J Org Chem. 2018 Apr 6;83(7):3607-3616. doi: 10.1021/acs.joc.7b03234. Epub 2018 Mar 19.

PMID:
29533629
17.

Inhibition of CD95/CD95L (FAS/FASLG) Signaling with APG101 Prevents Invasion and Enhances Radiation Therapy for Glioblastoma.

Blaes J, Thomé CM, Pfenning PN, Rübmann P, Sahm F, Wick A, Bunse T, Schmenger T, Sykora J, von Deimling A, Wiestler B, Merz C, Jugold M, Haberkorn U, Abdollahi A, Debus J, Gieffers C, Kunz C, Bendszus M, Kluge M, Platten M, Fricke H, Wick W, Lemke D.

Mol Cancer Res. 2018 May;16(5):767-776. doi: 10.1158/1541-7786.MCR-17-0563. Epub 2018 Feb 16.

PMID:
29453321
18.

6,7-dimethoxy-coumarin as a probe of hydration dynamics in biologically relevant systems.

Ghose A, Amaro M, Kovaricek P, Hof M, Sykora J.

Methods Appl Fluoresc. 2018 Feb 12;6(2):025005. doi: 10.1088/2050-6120/aaaa05.

PMID:
29360101
19.

Inflammatory bowel disease incidence in Czech children: A regional prospective study, 2000-2015.

Schwarz J, Sýkora J, Cvalínová D, Pomahačová R, Klečková J, Kryl M, Včelák P.

World J Gastroenterol. 2017 Jun 14;23(22):4090-4101. doi: 10.3748/wjg.v23.i22.4090.

20.

Internal dynamics in helical molecules studied by X-ray diffraction, NMR spectroscopy and DFT calculations.

Dračínský M, Storch J, Církva V, Císařová I, Sýkora J.

Phys Chem Chem Phys. 2017 Jan 25;19(4):2900-2907. doi: 10.1039/c6cp07552e.

PMID:
28079219
21.

hvTRA, a novel TRAIL receptor agonist, induces apoptosis and sustained growth retardation in melanoma.

Fleten KG, Flørenes VA, Prasmickaite L, Hill O, Sykora J, Mælandsmo GM, Engesæter B.

Cell Death Discov. 2016 Dec 12;2:16081. doi: 10.1038/cddiscovery.2016.81. eCollection 2016.

22.

First 2 cases with thiamine-responsive megaloblastic anemia in the Czech Republic, a rare form of monogenic diabetes mellitus: a novel mutation in the thiamine transporter SLC19A2 gene-intron 1 mutation c.204+2T>G.

Pomahačová R, Zamboryová J, Sýkora J, Paterová P, Fiklík K, Votava T, Černá Z, Jehlička P, Lád V, Šubrt I, Dort J, Dortová E.

Pediatr Diabetes. 2017 Dec;18(8):844-847. doi: 10.1111/pedi.12479. Epub 2016 Dec 22.

PMID:
28004468
23.

[Radiotherapy Indications in Patients with Hematological Malignancies During the Five Years Course of Modernized Center of Oncology and Radiotherapy Clinic in Pilsen].

Vokurka S, Fínek J, Svoboda T, Vojtíšek R, Votavová M, Havránek K, Salvét J, Šindelářová B, Mařan J, Sukovská E, Vasilev K, Schutzova M, Vozobulová V, Jindra P, Sýkora J.

Klin Onkol. 2016;29(4):313-4. Czech.

PMID:
27534789
24.

Effects of Renal Denervation Documented in the Austrian National Multicentre Renal Denervation Registry.

Zweiker D, Lambert T, Steinwender C, Weber T, Suppan M, Brussee H, Koppelstätter C, Kerschbaum J, Watschinger B, Hohenstein-Scheibenecker K, Reindl-Schwaighofer R, Sturmberger T, Kindslehner C, Weiss TW, Rohla M, Gruener P, Maister P, Auer J, Dechant C, Sykora J, Krismer C, Glaser S, Zweiker R.

PLoS One. 2016 Aug 16;11(8):e0161250. doi: 10.1371/journal.pone.0161250. eCollection 2016.

25.

Synthesis and in vitro cytotoxicity of acetylated 3-fluoro, 4-fluoro and 3,4-difluoro analogs of D-glucosamine and D-galactosamine.

Horník Š, Červenková Šťastná L, Cuřínová P, Sýkora J, Káňová K, Hrstka R, Císařová I, Dračínský M, Karban J.

Beilstein J Org Chem. 2016 Apr 20;12:750-9. doi: 10.3762/bjoc.12.75. eCollection 2016.

26.

A comprehensive LC/MS analysis of novel cyclopentenedione library.

Papouskova B, Bernard M, Ottenschlager J, Karban J, Velisek P, Hrbac J, Sykora J, Storch J, Vacek J.

J Pharm Biomed Anal. 2016 Sep 5;128:342-351. doi: 10.1016/j.jpba.2016.05.048. Epub 2016 Jun 2.

PMID:
27328361
27.

CD95 maintains stem cell-like and non-classical EMT programs in primary human glioblastoma cells.

Drachsler M, Kleber S, Mateos A, Volk K, Mohr N, Chen S, Cirovic B, Tüttenberg J, Gieffers C, Sykora J, Wirtz CR, Mueller W, Synowitz M, Martin-Villalba A.

Cell Death Dis. 2016 Apr 28;7:e2209. doi: 10.1038/cddis.2016.102.

28.

First case report of rare congenital adrenal insufficiency caused by mutations in the CYP11A1 gene in the Czech Republic.

Pomahačová R, Sýkora J, Zamboryová J, Paterová P, Varvařovská J, Šubrt I, Dort J, Dortová E.

J Pediatr Endocrinol Metab. 2016 Jun 1;29(6):749-52. doi: 10.1515/jpem-2015-0255.

PMID:
27008691
29.

Paediatric Rome III Criteria-Related Abdominal Pain Is Associated With Helicobacter pylori and Not With Calprotectin.

Sýkora J, Huml M, Siala K, Pomahačová R, Jehlička P, Liška J, Kuntscherová J, Schwarz J.

J Pediatr Gastroenterol Nutr. 2016 Oct;63(4):417-22. doi: 10.1097/MPG.0000000000001172.

PMID:
26913755
30.

Probing the Ca(2+)-assisted π-π interaction during Ca(2+)-dependent protein folding.

Matyska Liskova P, Fiser R, Macek P, Chmelik J, Sykora J, Bednarova L, Konopasek I, Bumba L.

Soft Matter. 2016 Jan 14;12(2):531-41. doi: 10.1039/c5sm01796c. Epub 2015 Oct 22.

PMID:
26489523
31.

High Efficacy but Low Potency of δ-Opioid Receptor-G Protein Coupling in Brij-58-Treated, Low-Density Plasma Membrane Fragments.

Roubalova L, Vosahlikova M, Brejchova J, Sykora J, Rudajev V, Svoboda P.

PLoS One. 2015 Aug 18;10(8):e0135664. doi: 10.1371/journal.pone.0135664. eCollection 2015.

32.

Sequential Therapy for Helicobacter pylori Infection in Treatment-naïve Children.

Schwarzer A, Bontems P, Urruzuno P, Kalach N, Iwanczak B, Roma-Giannikou E, Sykora J, Kindermann A, Casswall T, Cadranel S, Koletzko S.

Helicobacter. 2016 Apr;21(2):106-13. doi: 10.1111/hel.12240. Epub 2015 Jun 30.

PMID:
26123402
33.

Various extraction methods for obtaining stilbenes from grape cane of Vitis vinifera L.

Soural I, Vrchotová N, Tříska J, Balík J, Horník Š, Cuřínová P, Sýkora J.

Molecules. 2015 Apr 8;20(4):6093-112. doi: 10.3390/molecules20046093.

34.

Neutralization of the CD95 ligand by APG101 inhibits invasion of glioma cells in vitro.

Merz C, Strecker A, Sykora J, Hill O, Fricke H, Angel P, Gieffers C, Peterziel H.

Anticancer Drugs. 2015 Aug;26(7):716-27. doi: 10.1097/CAD.0000000000000237.

35.

Site-specific analysis of protein hydration based on unnatural amino acid fluorescence.

Amaro M, Brezovský J, Kováčová S, Sýkora J, Bednář D, Němec V, Lišková V, Kurumbang NP, Beerens K, Chaloupková R, Paruch K, Hof M, Damborský J.

J Am Chem Soc. 2015 Apr 22;137(15):4988-92. doi: 10.1021/jacs.5b01681. Epub 2015 Apr 9.

PMID:
25815779
36.

Cytotoxic Lipopeptide Muscotoxin A, Isolated from Soil Cyanobacterium Desmonostoc muscorum, Permeabilizes Phospholipid Membranes by Reducing Their Fluidity.

Tomek P, Hrouzek P, Kuzma M, Sýkora J, Fiser R, Cerný J, Novák P, Bártová S, Simek P, Hof M, Kavan D, Kopecký J.

Chem Res Toxicol. 2015 Feb 16;28(2):216-24.

PMID:
25621379
37.

CD95 promotes metastatic spread via Sck in pancreatic ductal adenocarcinoma.

Teodorczyk M, Kleber S, Wollny D, Sefrin JP, Aykut B, Mateos A, Herhaus P, Sancho-Martinez I, Hill O, Gieffers C, Sykora J, Weichert W, Eisen C, Trumpp A, Sprick MR, Bergmann F, Welsch T, Martin-Villalba A.

Cell Death Differ. 2015 Jul;22(7):1192-202. doi: 10.1038/cdd.2014.217. Epub 2015 Jan 23.

38.

Synthesis and characterization of a helicene-based imidazolium salt and its application in organic molecular electronics.

Storch J, Zadny J, Strasak T, Kubala M, Sykora J, Dusek M, Cirkva V, Matejka P, Krbal M, Vacek J.

Chemistry. 2015 Feb 2;21(6):2343-7. doi: 10.1002/chem.201405239. Epub 2014 Dec 11.

PMID:
25504775
39.

TRH-receptor mobility and function in intact and cholesterol-depleted plasma membrane of HEK293 cells stably expressing TRH-R-eGFP.

Brejchová J, Sýkora J, Ostašov P, Merta L, Roubalová L, Janáček J, Hof M, Svoboda P.

Biochim Biophys Acta. 2015 Mar;1848(3):781-96. doi: 10.1016/j.bbamem.2014.11.029. Epub 2014 Dec 6.

40.

Fluorescence quenching of (dimethylamino)naphthalene dyes Badan and Prodan by tryptophan in cytochromes P450 and micelles.

Pospíšil P, Luxem KE, Ener M, Sýkora J, Kocábová J, Gray HB, Vlček A Jr, Hof M.

J Phys Chem B. 2014 Aug 28;118(34):10085-91. doi: 10.1021/jp504625d. Epub 2014 Aug 14.

41.

Dynamics and hydration explain failed functional transformation in dehalogenase design.

Sykora J, Brezovsky J, Koudelakova T, Lahoda M, Fortova A, Chernovets T, Chaloupkova R, Stepankova V, Prokop Z, Smatanova IK, Hof M, Damborsky J.

Nat Chem Biol. 2014 Jun;10(6):428-30. doi: 10.1038/nchembio.1502. Epub 2014 Apr 13.

PMID:
24727901
42.

Photophysics of singlet and triplet intraligand excited states in [ReCl(CO)3(1-(2-pyridyl)-imidazo[1,5-α]pyridine)] complexes.

Blanco-Rodríguez AM, Kvapilová H, Sýkora J, Towrie M, Nervi C, Volpi G, Záliš S, Vlček A Jr.

J Am Chem Soc. 2014 Apr 23;136(16):5963-73. doi: 10.1021/ja413098m. Epub 2014 Apr 11.

PMID:
24669762
43.

Helicobacter pylori Infection in European children with gastro-duodenal ulcers and erosions.

Bontems P, Kalach N, Vanderpas J, Iwanczak B, Casswall T, Koletzko S, Oderda G, Martinez-Gomez MJ, Urruzuno P, Kindermann A, Sykora J, Veres G, Roma-Giannikou E, Pehlivanoglu E, Megraud F, Cadranel S.

Pediatr Infect Dis J. 2013 Dec;32(12):1324-9. doi: 10.1097/INF.0000000000000005.

PMID:
24569306
44.

Opioid-receptor (OR) signaling cascades in rat cerebral cortex and model cell lines: the role of plasma membrane structure.

Ujčíková H, Brejchová J, Vošahlíková M, Kagan D, Dlouhá K, Sýkora J, Merta L, Drastichová Z, Novotný J, Ostašov P, Roubalová L, Parenti M, Hof M, Svoboda P.

Physiol Res. 2014;63 Suppl 1:S165-76. Review.

45.

LC-NMR Technique in the Analysis of Phytosterols in Natural Extracts.

Horník S, Sajfrtová M, Karban J, Sýkora J, Březinová A, Wimmer Z.

J Anal Methods Chem. 2013;2013:526818. doi: 10.1155/2013/526818. Epub 2013 Dec 23.

46.

Hepatocyte expression of TRAIL pathway regulators correlates with histopathological and clinical parameters in chronic HCV infection.

Brost S, Zimmermann A, Koschny R, Sykora J, Stremmel W, Schirmacher P, Walczak H, Ganten TM.

Pathol Res Pract. 2014 Feb;210(2):83-91. doi: 10.1016/j.prp.2013.10.005. Epub 2013 Nov 7.

PMID:
24268735
47.

Cytosolic and nuclear caspase-8 have opposite impact on survival after liver resection for hepatocellular carcinoma.

Koschny R, Brost S, Hinz U, Sykora J, Batke EM, Singer S, Breuhahn K, Stremmel W, Walczak H, Schemmer P, Schirmacher P, Ganten TM.

BMC Cancer. 2013 Nov 9;13:532. doi: 10.1186/1471-2407-13-532.

48.

APG350 induces superior clustering of TRAIL receptors and shows therapeutic antitumor efficacy independent of cross-linking via Fcγ receptors.

Gieffers C, Kluge M, Merz C, Sykora J, Thiemann M, Schaal R, Fischer C, Branschädel M, Abhari BA, Hohenberger P, Fulda S, Fricke H, Hill O.

Mol Cancer Ther. 2013 Dec;12(12):2735-47. doi: 10.1158/1535-7163.MCT-13-0323. Epub 2013 Oct 7.

49.

Apoptotic signal molecules in skin biopsies of cutaneous lupus erythematosus: analysis using tissue microarray.

Toberer F, Sykora J, Göttel D, Hartschuh W, Werchau S, Enk A, Joos S, Krammer PH, Kuhn A.

Exp Dermatol. 2013 Oct;22(10):656-9. doi: 10.1111/exd.12216.

PMID:
24079735
50.

Separation and identification of 1,2,4-trihydroxynaphthalene-1-O-glucoside in Impatiens glandulifera Royle.

Tříska J, Vrchotová N, Sýkora J, Moos M.

Molecules. 2013 Jul 17;18(7):8429-39. doi: 10.3390/molecules18078429.

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