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Items: 1 to 50 of 251

1.

Current global trends in the incidence of pediatric-onset inflammatory bowel disease.

Sýkora J, Pomahačová R, Kreslová M, Cvalínová D, Štych P, Schwarz J.

World J Gastroenterol. 2018 Jul 7;24(25):2741-2763. doi: 10.3748/wjg.v24.i25.2741.

2.

Autoimmune disease, familial clustering and thyroid carcinoma coexistent with autoimmune thyroiditis in children and adolescence: A cross-sectional study from the Czech Republic.

Pomahacova R, Zamboryova J, Paterova P, Fiklik K, Cerna Z, Lad V, Skalicka E, Huml M, Sykora J.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2018 Jun 7. doi: 10.5507/bp.2018.030. [Epub ahead of print]

PMID:
29936527
3.

Monitoring of nucleophosmin oligomerization in live cells.

Holoubek A, Herman P, Sýkora J, Brodská B, Humpolíčková J, Kráčmarová M, Gášková D, Hof M, Kuželová K.

Methods Appl Fluoresc. 2018 Jun 29;6(3):035016. doi: 10.1088/2050-6120/aaccb9.

PMID:
29901450
4.

Xanthones Content in Swertia multicaulis D. Don from Nepal.

Timsina B, Kindlmann P, Rokaya MB, Vrchotová N, Tříska J, Horník Š, Sýkora J.

Molecules. 2018 May 3;23(5). pii: E1067. doi: 10.3390/molecules23051067.

5.

2-Bromo[6]helicene as a Key Intermediate for [6]Helicene Functionalization.

Jakubec M, Beránek T, Jakubík P, Sýkora J, Žádný J, Církva V, Storch J.

J Org Chem. 2018 Apr 6;83(7):3607-3616. doi: 10.1021/acs.joc.7b03234. Epub 2018 Mar 19.

PMID:
29533629
6.

Inhibition of CD95/CD95L (FAS/FASLG) Signaling with APG101 Prevents Invasion and Enhances Radiation Therapy for Glioblastoma.

Blaes J, Thomé CM, Pfenning PN, Rübmann P, Sahm F, Wick A, Bunse T, Schmenger T, Sykora J, von Deimling A, Wiestler B, Merz C, Jugold M, Haberkorn U, Abdollahi A, Debus J, Gieffers C, Kunz C, Bendszus M, Kluge M, Platten M, Fricke H, Wick W, Lemke D.

Mol Cancer Res. 2018 May;16(5):767-776. doi: 10.1158/1541-7786.MCR-17-0563. Epub 2018 Feb 16.

PMID:
29453321
7.

6,7-dimethoxy-coumarin as a probe of hydration dynamics in biologically relevant systems.

Ghose A, Amaro M, Kovaricek P, Hof M, Sykora J.

Methods Appl Fluoresc. 2018 Feb 12;6(2):025005. doi: 10.1088/2050-6120/aaaa05.

PMID:
29360101
8.

Inflammatory bowel disease incidence in Czech children: A regional prospective study, 2000-2015.

Schwarz J, Sýkora J, Cvalínová D, Pomahačová R, Klečková J, Kryl M, Včelák P.

World J Gastroenterol. 2017 Jun 14;23(22):4090-4101. doi: 10.3748/wjg.v23.i22.4090.

9.

Internal dynamics in helical molecules studied by X-ray diffraction, NMR spectroscopy and DFT calculations.

Dračínský M, Storch J, Církva V, Císařová I, Sýkora J.

Phys Chem Chem Phys. 2017 Jan 25;19(4):2900-2907. doi: 10.1039/c6cp07552e.

PMID:
28079219
10.

hvTRA, a novel TRAIL receptor agonist, induces apoptosis and sustained growth retardation in melanoma.

Fleten KG, Flørenes VA, Prasmickaite L, Hill O, Sykora J, Mælandsmo GM, Engesæter B.

Cell Death Discov. 2016 Dec 12;2:16081. doi: 10.1038/cddiscovery.2016.81. eCollection 2016.

11.

First 2 cases with thiamine-responsive megaloblastic anemia in the Czech Republic, a rare form of monogenic diabetes mellitus: a novel mutation in the thiamine transporter SLC19A2 gene-intron 1 mutation c.204+2T>G.

Pomahačová R, Zamboryová J, Sýkora J, Paterová P, Fiklík K, Votava T, Černá Z, Jehlička P, Lád V, Šubrt I, Dort J, Dortová E.

Pediatr Diabetes. 2017 Dec;18(8):844-847. doi: 10.1111/pedi.12479. Epub 2016 Dec 22.

PMID:
28004468
12.

[Radiotherapy Indications in Patients with Hematological Malignancies During the Five Years Course of Modernized Center of Oncology and Radiotherapy Clinic in Pilsen].

Vokurka S, Fínek J, Svoboda T, Vojtíšek R, Votavová M, Havránek K, Salvét J, Šindelářová B, Mařan J, Sukovská E, Vasilev K, Schutzova M, Vozobulová V, Jindra P, Sýkora J.

Klin Onkol. 2016;29(4):313-4. Czech.

PMID:
27534789
13.

Effects of Renal Denervation Documented in the Austrian National Multicentre Renal Denervation Registry.

Zweiker D, Lambert T, Steinwender C, Weber T, Suppan M, Brussee H, Koppelstätter C, Kerschbaum J, Watschinger B, Hohenstein-Scheibenecker K, Reindl-Schwaighofer R, Sturmberger T, Kindslehner C, Weiss TW, Rohla M, Gruener P, Maister P, Auer J, Dechant C, Sykora J, Krismer C, Glaser S, Zweiker R.

PLoS One. 2016 Aug 16;11(8):e0161250. doi: 10.1371/journal.pone.0161250. eCollection 2016.

14.

Synthesis and in vitro cytotoxicity of acetylated 3-fluoro, 4-fluoro and 3,4-difluoro analogs of D-glucosamine and D-galactosamine.

Horník Š, Červenková Šťastná L, Cuřínová P, Sýkora J, Káňová K, Hrstka R, Císařová I, Dračínský M, Karban J.

Beilstein J Org Chem. 2016 Apr 20;12:750-9. doi: 10.3762/bjoc.12.75. eCollection 2016.

15.

A comprehensive LC/MS analysis of novel cyclopentenedione library.

Papouskova B, Bernard M, Ottenschlager J, Karban J, Velisek P, Hrbac J, Sykora J, Storch J, Vacek J.

J Pharm Biomed Anal. 2016 Sep 5;128:342-351. doi: 10.1016/j.jpba.2016.05.048. Epub 2016 Jun 2.

PMID:
27328361
16.

CD95 maintains stem cell-like and non-classical EMT programs in primary human glioblastoma cells.

Drachsler M, Kleber S, Mateos A, Volk K, Mohr N, Chen S, Cirovic B, Tüttenberg J, Gieffers C, Sykora J, Wirtz CR, Mueller W, Synowitz M, Martin-Villalba A.

Cell Death Dis. 2016 Apr 28;7:e2209. doi: 10.1038/cddis.2016.102.

17.

First case report of rare congenital adrenal insufficiency caused by mutations in the CYP11A1 gene in the Czech Republic.

Pomahačová R, Sýkora J, Zamboryová J, Paterová P, Varvařovská J, Šubrt I, Dort J, Dortová E.

J Pediatr Endocrinol Metab. 2016 Jun 1;29(6):749-52. doi: 10.1515/jpem-2015-0255.

PMID:
27008691
18.

Paediatric Rome III Criteria-Related Abdominal Pain Is Associated With Helicobacter pylori and Not With Calprotectin.

Sýkora J, Huml M, Siala K, Pomahačová R, Jehlička P, Liška J, Kuntscherová J, Schwarz J.

J Pediatr Gastroenterol Nutr. 2016 Oct;63(4):417-22. doi: 10.1097/MPG.0000000000001172.

PMID:
26913755
19.

Probing the Ca(2+)-assisted π-π interaction during Ca(2+)-dependent protein folding.

Matyska Liskova P, Fiser R, Macek P, Chmelik J, Sykora J, Bednarova L, Konopasek I, Bumba L.

Soft Matter. 2016 Jan 14;12(2):531-41. doi: 10.1039/c5sm01796c. Epub 2015 Oct 22.

PMID:
26489523
20.

High Efficacy but Low Potency of δ-Opioid Receptor-G Protein Coupling in Brij-58-Treated, Low-Density Plasma Membrane Fragments.

Roubalova L, Vosahlikova M, Brejchova J, Sykora J, Rudajev V, Svoboda P.

PLoS One. 2015 Aug 18;10(8):e0135664. doi: 10.1371/journal.pone.0135664. eCollection 2015.

21.

Sequential Therapy for Helicobacter pylori Infection in Treatment-naïve Children.

Schwarzer A, Bontems P, Urruzuno P, Kalach N, Iwanczak B, Roma-Giannikou E, Sykora J, Kindermann A, Casswall T, Cadranel S, Koletzko S.

Helicobacter. 2016 Apr;21(2):106-13. doi: 10.1111/hel.12240. Epub 2015 Jun 30.

PMID:
26123402
22.

Various extraction methods for obtaining stilbenes from grape cane of Vitis vinifera L.

Soural I, Vrchotová N, Tříska J, Balík J, Horník Š, Cuřínová P, Sýkora J.

Molecules. 2015 Apr 8;20(4):6093-112. doi: 10.3390/molecules20046093.

23.

Neutralization of the CD95 ligand by APG101 inhibits invasion of glioma cells in vitro.

Merz C, Strecker A, Sykora J, Hill O, Fricke H, Angel P, Gieffers C, Peterziel H.

Anticancer Drugs. 2015 Aug;26(7):716-27. doi: 10.1097/CAD.0000000000000237.

24.

Site-specific analysis of protein hydration based on unnatural amino acid fluorescence.

Amaro M, Brezovský J, Kováčová S, Sýkora J, Bednář D, Němec V, Lišková V, Kurumbang NP, Beerens K, Chaloupková R, Paruch K, Hof M, Damborský J.

J Am Chem Soc. 2015 Apr 22;137(15):4988-92. doi: 10.1021/jacs.5b01681. Epub 2015 Apr 9.

PMID:
25815779
25.

Cytotoxic Lipopeptide Muscotoxin A, Isolated from Soil Cyanobacterium Desmonostoc muscorum, Permeabilizes Phospholipid Membranes by Reducing Their Fluidity.

Tomek P, Hrouzek P, Kuzma M, Sýkora J, Fiser R, Cerný J, Novák P, Bártová S, Simek P, Hof M, Kavan D, Kopecký J.

Chem Res Toxicol. 2015 Feb 16;28(2):216-24.

PMID:
25621379
26.

CD95 promotes metastatic spread via Sck in pancreatic ductal adenocarcinoma.

Teodorczyk M, Kleber S, Wollny D, Sefrin JP, Aykut B, Mateos A, Herhaus P, Sancho-Martinez I, Hill O, Gieffers C, Sykora J, Weichert W, Eisen C, Trumpp A, Sprick MR, Bergmann F, Welsch T, Martin-Villalba A.

Cell Death Differ. 2015 Jul;22(7):1192-202. doi: 10.1038/cdd.2014.217. Epub 2015 Jan 23.

27.

Synthesis and characterization of a helicene-based imidazolium salt and its application in organic molecular electronics.

Storch J, Zadny J, Strasak T, Kubala M, Sykora J, Dusek M, Cirkva V, Matejka P, Krbal M, Vacek J.

Chemistry. 2015 Feb 2;21(6):2343-7. doi: 10.1002/chem.201405239. Epub 2014 Dec 11.

PMID:
25504775
28.

TRH-receptor mobility and function in intact and cholesterol-depleted plasma membrane of HEK293 cells stably expressing TRH-R-eGFP.

Brejchová J, Sýkora J, Ostašov P, Merta L, Roubalová L, Janáček J, Hof M, Svoboda P.

Biochim Biophys Acta. 2015 Mar;1848(3):781-96. doi: 10.1016/j.bbamem.2014.11.029. Epub 2014 Dec 6.

29.

Fluorescence quenching of (dimethylamino)naphthalene dyes Badan and Prodan by tryptophan in cytochromes P450 and micelles.

Pospíšil P, Luxem KE, Ener M, Sýkora J, Kocábová J, Gray HB, Vlček A Jr, Hof M.

J Phys Chem B. 2014 Aug 28;118(34):10085-91. doi: 10.1021/jp504625d. Epub 2014 Aug 14.

30.

Dynamics and hydration explain failed functional transformation in dehalogenase design.

Sykora J, Brezovsky J, Koudelakova T, Lahoda M, Fortova A, Chernovets T, Chaloupkova R, Stepankova V, Prokop Z, Smatanova IK, Hof M, Damborsky J.

Nat Chem Biol. 2014 Jun;10(6):428-30. doi: 10.1038/nchembio.1502. Epub 2014 Apr 13.

PMID:
24727901
31.

Photophysics of singlet and triplet intraligand excited states in [ReCl(CO)3(1-(2-pyridyl)-imidazo[1,5-α]pyridine)] complexes.

Blanco-Rodríguez AM, Kvapilová H, Sýkora J, Towrie M, Nervi C, Volpi G, Záliš S, Vlček A Jr.

J Am Chem Soc. 2014 Apr 23;136(16):5963-73. doi: 10.1021/ja413098m. Epub 2014 Apr 11.

PMID:
24669762
32.

Helicobacter pylori Infection in European children with gastro-duodenal ulcers and erosions.

Bontems P, Kalach N, Vanderpas J, Iwanczak B, Casswall T, Koletzko S, Oderda G, Martinez-Gomez MJ, Urruzuno P, Kindermann A, Sykora J, Veres G, Roma-Giannikou E, Pehlivanoglu E, Megraud F, Cadranel S.

Pediatr Infect Dis J. 2013 Dec;32(12):1324-9. doi: 10.1097/INF.0000000000000005.

PMID:
24569306
33.

Opioid-receptor (OR) signaling cascades in rat cerebral cortex and model cell lines: the role of plasma membrane structure.

Ujčíková H, Brejchová J, Vošahlíková M, Kagan D, Dlouhá K, Sýkora J, Merta L, Drastichová Z, Novotný J, Ostašov P, Roubalová L, Parenti M, Hof M, Svoboda P.

Physiol Res. 2014;63 Suppl 1:S165-76. Review.

34.

LC-NMR Technique in the Analysis of Phytosterols in Natural Extracts.

Horník S, Sajfrtová M, Karban J, Sýkora J, Březinová A, Wimmer Z.

J Anal Methods Chem. 2013;2013:526818. doi: 10.1155/2013/526818. Epub 2013 Dec 23.

35.

Hepatocyte expression of TRAIL pathway regulators correlates with histopathological and clinical parameters in chronic HCV infection.

Brost S, Zimmermann A, Koschny R, Sykora J, Stremmel W, Schirmacher P, Walczak H, Ganten TM.

Pathol Res Pract. 2014 Feb;210(2):83-91. doi: 10.1016/j.prp.2013.10.005. Epub 2013 Nov 7.

PMID:
24268735
36.

Cytosolic and nuclear caspase-8 have opposite impact on survival after liver resection for hepatocellular carcinoma.

Koschny R, Brost S, Hinz U, Sykora J, Batke EM, Singer S, Breuhahn K, Stremmel W, Walczak H, Schemmer P, Schirmacher P, Ganten TM.

BMC Cancer. 2013 Nov 9;13:532. doi: 10.1186/1471-2407-13-532.

37.

APG350 induces superior clustering of TRAIL receptors and shows therapeutic antitumor efficacy independent of cross-linking via Fcγ receptors.

Gieffers C, Kluge M, Merz C, Sykora J, Thiemann M, Schaal R, Fischer C, Branschädel M, Abhari BA, Hohenberger P, Fulda S, Fricke H, Hill O.

Mol Cancer Ther. 2013 Dec;12(12):2735-47. doi: 10.1158/1535-7163.MCT-13-0323. Epub 2013 Oct 7.

38.

Apoptotic signal molecules in skin biopsies of cutaneous lupus erythematosus: analysis using tissue microarray.

Toberer F, Sykora J, Göttel D, Hartschuh W, Werchau S, Enk A, Joos S, Krammer PH, Kuhn A.

Exp Dermatol. 2013 Oct;22(10):656-9. doi: 10.1111/exd.12216.

PMID:
24079735
39.

Separation and identification of 1,2,4-trihydroxynaphthalene-1-O-glucoside in Impatiens glandulifera Royle.

Tříska J, Vrchotová N, Sýkora J, Moos M.

Molecules. 2013 Jul 17;18(7):8429-39. doi: 10.3390/molecules18078429.

40.

Are time-dependent fluorescence shifts at the tunnel mouth of haloalkane dehalogenase enzymes dependent on the choice of the chromophore?

Amaro M, Brezovský J, Kováčová S, Maier L, Chaloupková R, Sýkora J, Paruch K, Damborský J, Hof M.

J Phys Chem B. 2013 Jul 3;117(26):7898-906. doi: 10.1021/jp403708c. Epub 2013 Jun 20.

PMID:
23781851
41.

Polystyrene nanofiber materials modified with an externally bound porphyrin photosensitizer.

Henke P, Lang K, Kubát P, Sýkora J, Slouf M, Mosinger J.

ACS Appl Mater Interfaces. 2013 May;5(9):3776-83. doi: 10.1021/am4004057. Epub 2013 Apr 23.

PMID:
23566280
42.

Expansion of access tunnels and active-site cavities influence activity of haloalkane dehalogenases in organic cosolvents.

Stepankova V, Khabiri M, Brezovsky J, Pavelka A, Sykora J, Amaro M, Minofar B, Prokop Z, Hof M, Ettrich R, Chaloupkova R, Damborsky J.

Chembiochem. 2013 May 10;14(7):890-7. doi: 10.1002/cbic.201200733. Epub 2013 Apr 5.

PMID:
23564727
43.

FLIM studies of 22- and 25-NBD-cholesterol in living HEK293 cells: plasma membrane change induced by cholesterol depletion.

Ostašov P, Sýkora J, Brejchová J, Olżyńska A, Hof M, Svoboda P.

Chem Phys Lipids. 2013 Feb-Mar;167-168:62-9. doi: 10.1016/j.chemphyslip.2013.02.006. Epub 2013 Mar 4.

PMID:
23466534
44.

Effect of heavy water on phospholipid membranes: experimental confirmation of molecular dynamics simulations.

Beranová L, Humpolíčková J, Sýkora J, Benda A, Cwiklik L, Jurkiewicz P, Gröbner G, Hof M.

Phys Chem Chem Phys. 2012 Nov 14;14(42):14516-22. doi: 10.1039/c2cp41275f. Epub 2012 Aug 6.

PMID:
22870507
45.

Structural control of 1A2u-to-3A2u intersystem crossing in diplatinum(II,II) complexes.

Durrell AC, Keller GE, Lam YC, Sýkora J, Vlček A Jr, Gray HB.

J Am Chem Soc. 2012 Aug 29;134(34):14201-7. doi: 10.1021/ja305666b. Epub 2012 Aug 16.

PMID:
22867057
46.

Spin-orbit treatment of UV-vis absorption spectra and photophysics of rhenium(I) carbonyl-bipyridine complexes: MS-CASPT2 and TD-DFT analysis.

Heydová R, Gindensperger E, Romano R, Sýkora J, Vlček A Jr, Záliš S, Daniel C.

J Phys Chem A. 2012 Nov 26;116(46):11319-29. doi: 10.1021/jp305461z. Epub 2012 Aug 17.

PMID:
22817529
47.

Unprecedented meta-substitution of calixarenes: direct way to inherently chiral derivatives.

Slavik P, Dudic M, Flidrova K, Sykora J, Cisarova I, Böhm S, Lhotak P.

Org Lett. 2012 Jul 20;14(14):3628-31. doi: 10.1021/ol301420t. Epub 2012 Jul 3.

PMID:
22758402
48.

[Identification of molecular markers in children with acute myeloid leukemia (AML)].

Ilenčíková D, Sýkora J, Mikulášová Z, Repiská V.

Klin Onkol. 2012;25(1):26-35. Slovak.

PMID:
22348217
49.

The effect of solvent accessible surface on Hammett-type dependencies of infinite dilution (29)Si and (13)C NMR shifts in ring substituted silylated phenols dissolved in chloroform and acetone.

Blechta V, Sabata S, Sýkora J, Hetflejš J, Soukupová L, Schraml J.

Magn Reson Chem. 2012 Feb;50(2):128-34. doi: 10.1002/mrc.2860. Epub 2012 Feb 15.

PMID:
22336952
50.

TRAIL dependent fratricidal killing of gp120 primed hepatocytes by HCV core expressing hepatocytes.

Rizza SA, Challagundla KB, Natesampillai S, Bren GD, Sykora J, Walczak H, Badley AD.

PLoS One. 2011;6(11):e27171. doi: 10.1371/journal.pone.0027171. Epub 2011 Nov 14.

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