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Items: 1 to 50 of 135

1.
2.

Gender and health literacy: men's health beliefs and behaviour in Trinidad.

Wills J, Sykes S, Hardy S, Kelly M, Moorley C, Ocho O.

Health Promot Int. 2019 Aug 13. pii: daz076. doi: 10.1093/heapro/daz076. [Epub ahead of print]

PMID:
31407795
3.

NCAM1 supports therapy resistance and LSC function in AML.

Sykes SM.

Blood. 2019 May 23;133(21):2247-2248. doi: 10.1182/blood-2019-03-901017. No abstract available.

PMID:
31122937
4.

Challenges and opportunities in building critical health literacy.

Sykes S, Wills J.

Glob Health Promot. 2018 Nov 14:1757975918789352. doi: 10.1177/1757975918789352. [Epub ahead of print]

PMID:
30427253
5.

BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance.

Nacson J, Krais JJ, Bernhardy AJ, Clausen E, Feng W, Wang Y, Nicolas E, Cai KQ, Tricarico R, Hua X, DiMarcantonio D, Martinez E, Zong D, Handorf EA, Bellacosa A, Testa JR, Nussenzweig A, Gupta GP, Sykes SM, Johnson N.

Cell Rep. 2018 Oct 30;25(5):1384. doi: 10.1016/j.celrep.2018.10.009. No abstract available.

6.

BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance.

Nacson J, Krais JJ, Bernhardy AJ, Clausen E, Feng W, Wang Y, Nicolas E, Cai KQ, Tricarico R, Hua X, DiMarcantonio D, Martinez E, Zong D, Handorf EA, Bellacosa A, Testa JR, Nussenzweig A, Gupta GP, Sykes SM, Johnson N.

Cell Rep. 2018 Sep 25;24(13):3513-3527.e7. doi: 10.1016/j.celrep.2018.08.086. Erratum in: Cell Rep. 2018 Oct 30;25(5):1384.

7.

Tyrosine kinase inhibitor-induced defects in DNA repair sensitize FLT3(ITD)-positive leukemia cells to PARP1 inhibitors.

Maifrede S, Nieborowska-Skorska M, Sullivan-Reed K, Dasgupta Y, Podszywalow-Bartnicka P, Le BV, Solecka M, Lian Z, Belyaeva EA, Nersesyan A, Machnicki MM, Toma M, Chatain N, Rydzanicz M, Zhao H, Jelinek J, Piwocka K, Sliwinski T, Stoklosa T, Ploski R, Fischer T, Sykes SM, Koschmieder S, Bullinger L, Valent P, Wasik MA, Huang J, Skorski T.

Blood. 2018 Jul 5;132(1):67-77. doi: 10.1182/blood-2018-02-834895. Epub 2018 May 21.

8.

Urinary angiotensinogen excretion in Australian Indigenous and non-Indigenous pregnant women.

Pringle KG, de Meaultsart CC, Sykes SD, Weatherall LJ, Keogh L, Clausen DC, Dekker GA, Smith R, Roberts CT, Rae KM, Lumbers ER.

Pregnancy Hypertens. 2018 Apr;12:110-117. doi: 10.1016/j.preghy.2018.04.009. Epub 2018 Apr 11.

PMID:
29674190
9.

RET-mediated autophagy suppression as targetable co-dependence in acute myeloid leukemia.

Rudat S, Pfaus A, Cheng YY, Holtmann J, Ellegast JM, Bühler C, Marcantonio DD, Martinez E, Göllner S, Wickenhauser C, Müller-Tidow C, Lutz C, Bullinger L, Milsom MD, Sykes SM, Fröhling S, Scholl C.

Leukemia. 2018 Oct;32(10):2189-2202. doi: 10.1038/s41375-018-0102-4. Epub 2018 Mar 22.

PMID:
29654265
10.

Enhancing Care Transitions for Older People through Interprofessional Simulation: A Mixed Method Evaluation.

Sykes S, Baillie L, Thomas B, Scotter J, Martin F.

Int J Integr Care. 2017 Nov 13;17(6):3. doi: 10.5334/ijic.3055.

11.

The -2518 A/G polymorphism of the monocyte chemoattractant protein-1 as a candidate genetic predisposition factor for secondary myelofibrosis and biomarker of disease severity.

Masselli E, Carubbi C, Cambò B, Pozzi G, Gobbi G, Mirandola P, Follini E, Pagliaro L, Di Marcantonio D, Bonatti F, Percesepe A, Sykes SM, Aversa F, Vitale M.

Leukemia. 2018 Oct;32(10):2266-2270. doi: 10.1038/s41375-018-0088-y. Epub 2018 Mar 6. No abstract available.

12.

MLL-AF9 leukemias are sensitive to PARP1 inhibitors combined with cytotoxic drugs.

Maifrede S, Martinez E, Nieborowska-Skorska M, Di Marcantonio D, Hulse M, Le BV, Zhao H, Piwocka K, Tempera I, Sykes SM, Skorski T.

Blood Adv. 2017 Aug 9;1(19):1467-1472. doi: 10.1182/bloodadvances.2017006247. eCollection 2017 Aug 22.

13.

Protein Kinase C Epsilon Is a Key Regulator of Mitochondrial Redox Homeostasis in Acute Myeloid Leukemia.

Di Marcantonio D, Martinez E, Sidoli S, Vadaketh J, Nieborowska-Skorska M, Gupta A, Meadows JM, Ferraro F, Masselli E, Challen GA, Milsom MD, Scholl C, Fröhling S, Balachandran S, Skorski T, Garcia BA, Mirandola P, Gobbi G, Garzon R, Vitale M, Sykes SM.

Clin Cancer Res. 2018 Feb 1;24(3):608-618. doi: 10.1158/1078-0432.CCR-17-2684. Epub 2017 Nov 10.

14.

Do nurses' personal health behaviours impact on their health promotion practice? A systematic review.

Kelly M, Wills J, Sykes S.

Int J Nurs Stud. 2017 Nov;76:62-77. doi: 10.1016/j.ijnurstu.2017.08.008. Epub 2017 Aug 23. Review.

PMID:
28938104
15.

Tracing Genetic Exchange and Biogeography of Cryptococcus neoformans var. grubii at the Global Population Level.

Rhodes J, Desjardins CA, Sykes SM, Beale MA, Vanhove M, Sakthikumar S, Chen Y, Gujja S, Saif S, Chowdhary A, Lawson DJ, Ponzio V, Colombo AL, Meyer W, Engelthaler DM, Hagen F, Illnait-Zaragozi MT, Alanio A, Vreulink JM, Heitman J, Perfect JR, Litvintseva AP, Bicanic T, Harrison TS, Fisher MC, Cuomo CA.

Genetics. 2017 Sep;207(1):327-346. doi: 10.1534/genetics.117.203836. Epub 2017 Jul 5.

16.

Population genomics and the evolution of virulence in the fungal pathogen Cryptococcus neoformans.

Desjardins CA, Giamberardino C, Sykes SM, Yu CH, Tenor JL, Chen Y, Yang T, Jones AM, Sun S, Haverkamp MR, Heitman J, Litvintseva AP, Perfect JR, Cuomo CA.

Genome Res. 2017 Jul;27(7):1207-1219. doi: 10.1101/gr.218727.116.

17.

Gene expression and mutation-guided synthetic lethality eradicates proliferating and quiescent leukemia cells.

Nieborowska-Skorska M, Sullivan K, Dasgupta Y, Podszywalow-Bartnicka P, Hoser G, Maifrede S, Martinez E, Di Marcantonio D, Bolton-Gillespie E, Cramer-Morales K, Lee J, Li M, Slupianek A, Gritsyuk D, Cerny-Reiterer S, Seferynska I, Stoklosa T, Bullinger L, Zhao H, Gorbunova V, Piwocka K, Valent P, Civin CI, Muschen M, Dick JE, Wang JC, Bhatia S, Bhatia R, Eppert K, Minden MD, Sykes SM, Skorski T.

J Clin Invest. 2017 Jun 1;127(6):2392-2406. doi: 10.1172/JCI90825. Epub 2017 May 8.

18.

Feline Respiratory Extramedullary Plasmacytoma with Lymph Node Metastasis and Intrahistiocytic Amyloid.

Sykes SE, Byfield V, Sullivan L, Bender SJ, Moore PF, Sánchez MD.

J Comp Pathol. 2017 Feb - Apr;156(2-3):173-177. doi: 10.1016/j.jcpa.2016.11.270. Epub 2016 Dec 22.

PMID:
28017340
19.

Phosphorylation of Eukaryotic Initiation Factor-2α during Stress and Encystation in Entamoeba Species.

Hendrick HM, Welter BH, Hapstack MA, Sykes SE, Sullivan WJ Jr, Temesvari LA.

PLoS Pathog. 2016 Dec 8;12(12):e1006085. doi: 10.1371/journal.ppat.1006085. eCollection 2016 Dec.

20.

JUN is a key transcriptional regulator of the unfolded protein response in acute myeloid leukemia.

Zhou C, Martinez E, Di Marcantonio D, Solanki-Patel N, Aghayev T, Peri S, Ferraro F, Skorski T, Scholl C, Fröhling S, Balachandran S, Wiest DL, Sykes SM.

Leukemia. 2017 May;31(5):1196-1205. doi: 10.1038/leu.2016.329. Epub 2016 Nov 14.

21.

Genome Diversity, Recombination, and Virulence across the Major Lineages of Paracoccidioides.

Muñoz JF, Farrer RA, Desjardins CA, Gallo JE, Sykes S, Sakthikumar S, Misas E, Whiston EA, Bagagli E, Soares CM, Teixeira MM, Taylor JW, Clay OK, McEwen JG, Cuomo CA.

mSphere. 2016 Sep 28;1(5). pii: e00213-16. eCollection 2016 Sep-Oct.

22.

A rare DNA contact mutation in cancer confers p53 gain-of-function and tumor cell survival via TNFAIP8 induction.

Monteith JA, Mellert H, Sammons MA, Kuswanto LA, Sykes SM, Resnick-Silverman L, Manfredi JJ, Berger SL, McMahon SB.

Mol Oncol. 2016 Oct;10(8):1207-20. doi: 10.1016/j.molonc.2016.05.007. Epub 2016 Jun 7.

23.

The identity crisis of Hif-1α in HSC biology.

Sykes SM.

Blood. 2016 Jun 9;127(23):2782-4. doi: 10.1182/blood-2016-04-710459. No abstract available.

PMID:
27282941
24.

Genome analysis of three Pneumocystis species reveals adaptation mechanisms to life exclusively in mammalian hosts.

Ma L, Chen Z, Huang da W, Kutty G, Ishihara M, Wang H, Abouelleil A, Bishop L, Davey E, Deng R, Deng X, Fan L, Fantoni G, Fitzgerald M, Gogineni E, Goldberg JM, Handley G, Hu X, Huber C, Jiao X, Jones K, Levin JZ, Liu Y, Macdonald P, Melnikov A, Raley C, Sassi M, Sherman BT, Song X, Sykes S, Tran B, Walsh L, Xia Y, Yang J, Young S, Zeng Q, Zheng X, Stephens R, Nusbaum C, Birren BW, Azadi P, Lempicki RA, Cuomo CA, Kovacs JA.

Nat Commun. 2016 Feb 22;7:10740. doi: 10.1038/ncomms10740.

25.

Extracellular Vesicles from Trypanosoma brucei Mediate Virulence Factor Transfer and Cause Host Anemia.

Szempruch AJ, Sykes SE, Kieft R, Dennison L, Becker AC, Gartrell A, Martin WJ, Nakayasu ES, Almeida IC, Hajduk SL, Harrington JM.

Cell. 2016 Jan 14;164(1-2):246-257. doi: 10.1016/j.cell.2015.11.051.

26.

Circulating and intrarenal renin-angiotensin systems in healthy men and nonpregnant women.

Pringle KG, Sykes SD, Lumbers ER.

Physiol Rep. 2015 Oct;3(10). pii: e12586. doi: 10.14814/phy2.12586.

27.

Clonal evolution of preleukemic hematopoietic stem cells in acute myeloid leukemia.

Sykes SM, Kokkaliaris KD, Milsom MD, Levine RL, Majeti R.

Exp Hematol. 2015 Dec;43(12):989-92. doi: 10.1016/j.exphem.2015.08.012. Epub 2015 Oct 9. Review.

28.

PKCε as a novel promoter of skeletal muscle differentiation and regeneration.

Di Marcantonio D, Galli D, Carubbi C, Gobbi G, Queirolo V, Martini S, Merighi S, Vaccarezza M, Maffulli N, Sykes SM, Vitale M, Mirandola P.

Exp Cell Res. 2015 Nov 15;339(1):10-9. doi: 10.1016/j.yexcr.2015.09.017. Epub 2015 Sep 30.

29.

Methylation of promoter regions of genes of the human intrauterine Renin Angiotensin system and their expression.

Sykes SD, Mitchell C, Pringle KG, Wang Y, Zakar T, Lumbers ER.

Int J Endocrinol. 2015;2015:459818. doi: 10.1155/2015/459818. Epub 2015 Mar 30.

30.

Regulation of the Renin-Angiotensin System Pathways in the Human Decidua.

Wang Y, Lumbers ER, Sykes SD, Pringle KG.

Reprod Sci. 2015 Jul;22(7):865-72. doi: 10.1177/1933719114565029. Epub 2014 Dec 28.

31.

Transmembrane Inhibitor of RICTOR/mTORC2 in Hematopoietic Progenitors.

Lee D, Sykes SM, Kalaitzidis D, Lane AA, Kfoury Y, Raaijmakers MH, Wang YH, Armstrong SA, Scadden DT.

Stem Cell Reports. 2014 Nov 11;3(5):832-40. doi: 10.1016/j.stemcr.2014.08.011. Epub 2014 Sep 25.

32.

The krebs cycle enzyme α-ketoglutarate decarboxylase is an essential glycosomal protein in bloodstream African trypanosomes.

Sykes S, Szempruch A, Hajduk S.

Eukaryot Cell. 2015 Mar;14(3):206-15. doi: 10.1128/EC.00214-14. Epub 2014 Nov 21.

33.

mTOR kinase inhibitors promote antibody class switching via mTORC2 inhibition.

Limon JJ, So L, Jellbauer S, Chiu H, Corado J, Sykes SM, Raffatellu M, Fruman DA.

Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):E5076-85. doi: 10.1073/pnas.1407104111. Epub 2014 Nov 10.

34.

Effect of enhanced information, values clarification, and removal of financial barriers on use of prenatal genetic testing: a randomized clinical trial.

Kuppermann M, Pena S, Bishop JT, Nakagawa S, Gregorich SE, Sit A, Vargas J, Caughey AB, Sykes S, Pierce L, Norton ME.

JAMA. 2014 Sep 24;312(12):1210-7. doi: 10.1001/jama.2014.11479.

35.

Inhibiting stromal cell heparan sulfate synthesis improves stem cell mobilization and enables engraftment without cytotoxic conditioning.

Saez B, Ferraro F, Yusuf RZ, Cook CM, Yu VW, Pardo-Saganta A, Sykes SM, Palchaudhuri R, Schajnovitz A, Lotinun S, Lymperi S, Mendez-Ferrer S, Toro RD, Day R, Vasic R, Acharya SS, Baron R, Lin CP, Yamaguchi Y, Wagers AJ, Scadden DT.

Blood. 2014 Nov 6;124(19):2937-47. doi: 10.1182/blood-2014-08-593426. Epub 2014 Sep 8.

36.

Analysis of a food-borne fungal pathogen outbreak: virulence and genome of a Mucor circinelloides isolate from yogurt.

Lee SC, Billmyre RB, Li A, Carson S, Sykes SM, Huh EY, Mieczkowski P, Ko DC, Cuomo CA, Heitman J.

MBio. 2014 Jul 8;5(4):e01390-14. doi: 10.1128/mBio.01390-14.

37.

Requirement for CDK6 in MLL-rearranged acute myeloid leukemia.

Placke T, Faber K, Nonami A, Putwain SL, Salih HR, Heidel FH, Krämer A, Root DE, Barbie DA, Krivtsov AV, Armstrong SA, Hahn WC, Huntly BJ, Sykes SM, Milsom MD, Scholl C, Fröhling S.

Blood. 2014 Jul 3;124(1):13-23. doi: 10.1182/blood-2014-02-558114. Epub 2014 Apr 24.

38.

Comparative genomic and transcriptomic analysis of wangiella dermatitidis, a major cause of phaeohyphomycosis and a model black yeast human pathogen.

Chen Z, Martinez DA, Gujja S, Sykes SM, Zeng Q, Szaniszlo PJ, Wang Z, Cuomo CA.

G3 (Bethesda). 2014 Apr 16;4(4):561-78. doi: 10.1534/g3.113.009241.

39.

Modeling human hematopoietic stem cell biology in the mouse.

Sykes SM, Scadden DT.

Semin Hematol. 2013 Apr;50(2):92-100. doi: 10.1053/j.seminhematol.2013.03.029. Epub 2013 Jun 11. Review.

40.

Proplatelet generation in the mouse requires PKCε-dependent RhoA inhibition.

Gobbi G, Mirandola P, Carubbi C, Masselli E, Sykes SM, Ferraro F, Nouvenne A, Thon JN, Italiano JE Jr, Vitale M.

Blood. 2013 Aug 15;122(7):1305-11. doi: 10.1182/blood-2013-04-490599. Epub 2013 Jul 9.

41.

Distinctive expansion of potential virulence genes in the genome of the oomycete fish pathogen Saprolegnia parasitica.

Jiang RH, de Bruijn I, Haas BJ, Belmonte R, Löbach L, Christie J, van den Ackerveken G, Bottin A, Bulone V, Díaz-Moreno SM, Dumas B, Fan L, Gaulin E, Govers F, Grenville-Briggs LJ, Horner NR, Levin JZ, Mammella M, Meijer HJ, Morris P, Nusbaum C, Oome S, Phillips AJ, van Rooyen D, Rzeszutek E, Saraiva M, Secombes CJ, Seidl MF, Snel B, Stassen JH, Sykes S, Tripathy S, van den Berg H, Vega-Arreguin JC, Wawra S, Young SK, Zeng Q, Dieguez-Uribeondo J, Russ C, Tyler BM, van West P.

PLoS Genet. 2013 Jun;9(6):e1003272. doi: 10.1371/journal.pgen.1003272. Epub 2013 Jun 13.

42.

Fetal sex and the circulating renin-angiotensin system during early gestation in women who later develop preeclampsia or gestational hypertension.

Sykes SD, Pringle KG, Zhou A, Dekker GA, Roberts CT, Lumbers ER; SCOPE consortium.

J Hum Hypertens. 2014 Feb;28(2):133-9. doi: 10.1038/jhh.2013.51. Epub 2013 Jun 20.

PMID:
23782994
43.

PP036. The intrarenal renin-angiotensin system and pregnancy outcome.

Pringle K, Lumbers E, Sykes S, Weatherall L, Clausen D, Rae K, Smith R.

Pregnancy Hypertens. 2013 Apr;3(2):79-80. doi: 10.1016/j.preghy.2013.04.063. Epub 2013 Jun 6.

PMID:
26105892
44.

PP025. Measurement of the activity of the circulating and intrarenal renin-angiotensin system (iRAS) in pregnant and non-pregnant subjects.

Lumbers E, Pringle K, Sykes S, Weatherall L, Clausen D, Rae K, Smith R.

Pregnancy Hypertens. 2013 Apr;3(2):76. doi: 10.1016/j.preghy.2013.04.053. Epub 2013 Jun 6.

PMID:
26105881
45.

The balance between human maternal plasma angiotensin II and angiotensin 1-7 levels in early gestation pregnancy is influenced by fetal sex.

Sykes SD, Pringle KG, Zhou A, Dekker GA, Roberts CT, Lumbers ER; SCOPE Consortium.

J Renin Angiotensin Aldosterone Syst. 2014 Dec;15(4):523-31. doi: 10.1177/1470320313477174. Epub 2013 Feb 25.

PMID:
23438673
46.

Understanding critical health literacy: a concept analysis.

Sykes S, Wills J, Rowlands G, Popple K.

BMC Public Health. 2013 Feb 18;13:150. doi: 10.1186/1471-2458-13-150. Review.

47.

Inflammatory and steroid receptor gene methylation in the human amnion and decidua.

Mitchell CM, Sykes SD, Pan X, Pringle KG, Lumbers ER, Hirst JJ, Zakar T.

J Mol Endocrinol. 2013 Mar 18;50(2):267-77. doi: 10.1530/JME-12-0211. Print 2013 Apr.

PMID:
23393306
48.

Sequencing and characterization of the complete mitochondrial genomes of three Pneumocystis species provide new insights into divergence between human and rodent Pneumocystis.

Ma L, Huang DW, Cuomo CA, Sykes S, Fantoni G, Das B, Sherman BT, Yang J, Huber C, Xia Y, Davey E, Kutty G, Bishop L, Sassi M, Lempicki RA, Kovacs JA.

FASEB J. 2013 May;27(5):1962-72. doi: 10.1096/fj.12-224444. Epub 2013 Feb 7.

49.

CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPARγ signaling.

Faber K, Bullinger L, Ragu C, Garding A, Mertens D, Miller C, Martin D, Walcher D, Döhner K, Döhner H, Claus R, Plass C, Sykes SM, Lane SW, Scholl C, Fröhling S.

J Clin Invest. 2013 Jan;123(1):299-314. doi: 10.1172/JCI64745. Epub 2012 Dec 3.

50.

Staff and relatives' perspectives on the aggressive behaviour of older people with dementia in residential care: a qualitative study.

Duxbury J, Pulsford D, Hadi M, Sykes S.

J Psychiatr Ment Health Nurs. 2013 Nov;20(9):792-800. doi: 10.1111/jpm.12018. Epub 2012 Nov 20.

PMID:
23163804

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