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Items: 1 to 50 of 792

1.

Impact of CMV reactivation, treatment approaches and immune reconstitution in a nonmyeloablative tolerance induction protocol in Cynomolgus macaques.

Alonso-Guallart P, Duran-Struuck R, Zitsman JS, Sameroff S, Pereira M, Stern J, Berglund E, Llore N, Pierre G, Lopes E, Kofman SB, Danton M, Sondermeijer HP, Woodland D, Kato Y, Ekanayake-Alper DK, Iuga AC, Wuu CS, Wu A, Lipkin WI, Tokarz R, Sykes M, Griesemer A.

Transplantation. 2019 Aug 1. doi: 10.1097/TP.0000000000002893. [Epub ahead of print]

PMID:
31385931
2.

Siplizumab selectively depletes effector memory T cells and promotes a relative expansion of alloreactive regulatory T cells in vitro.

Podestà MA, Binder C, Sellberg F, DeWolf S, Shonts B, Ho SH, Obradovic A, Waffarn E, Danzl N, Berglund D, Sykes M.

Am J Transplant. 2019 Jul 18. doi: 10.1111/ajt.15533. [Epub ahead of print]

PMID:
31319439
3.

Preparation of hybrid porcine thymus containing non-human primate thymic epithelial cells in miniature swine.

Sekijima M, Sahara H, Shimizu A, Iwanaga T, Murokawa T, Ariyoshi Y, Pomposelli T, Khosravi Maharlooei M, Sykes M, Yamada K.

Xenotransplantation. 2019 Jul 10:e12543. doi: 10.1111/xen.12543. [Epub ahead of print]

PMID:
31293016
4.

Total Synthesis of the Antimalarial Ascidian Natural Product Albopunctatone.

Pullella GA, Wdowiak AP, Sykes ML, Lucantoni L, Sukhoverkov KV, Zulfiqar B, Sobolev AN, West NP, Mylne JS, Avery VM, Piggott MJ.

Org Lett. 2019 Jul 19;21(14):5519-5523. doi: 10.1021/acs.orglett.9b01838. Epub 2019 Jul 9.

PMID:
31287326
5.

The cubane paradigm in bioactive molecule discovery: further scope, limitations and the cyclooctatetraene complement.

Houston SD, Fahrenhorst-Jones T, Xing H, Chalmers BA, Sykes ML, Stok JE, Farfan Soto C, Burns JM, Bernhardt PV, De Voss JJ, Boyle GM, Smith MT, Tsanaktsidis J, Savage GP, Avery VM, Williams CM.

Org Biomol Chem. 2019 Jul 17;17(28):6790-6798. doi: 10.1039/c9ob01238a.

PMID:
31241113
6.

Harnessing Hematopoietic Stem Cell Low Intracellular Calcium Improves Their Maintenance In Vitro.

Luchsinger LL, Strikoudis A, Danzl NM, Bush EC, Finlayson MO, Satwani P, Sykes M, Yazawa M, Snoeck HW.

Cell Stem Cell. 2019 Aug 1;25(2):225-240.e7. doi: 10.1016/j.stem.2019.05.002. Epub 2019 Jun 6.

PMID:
31178255
7.

Discovery of CDK5 Inhibitors through Structure-Guided Approach.

Khair NZ, Lenjisa JL, Tadesse S, Kumarasiri M, Basnet SKC, Mekonnen LB, Li M, Diab S, Sykes MJ, Albrecht H, Milne R, Wang S.

ACS Med Chem Lett. 2019 Mar 20;10(5):786-791. doi: 10.1021/acsmedchemlett.9b00029. eCollection 2019 May 9.

PMID:
31098000
8.

Third WHO Global Consultation on Regulatory Requirements for Xenotransplantation Clinical Trials, Changsha, Hunan, China December 12-14, 2018: "The 2018 Changsha Communiqué" The 10-Year Anniversary of The International Consultation on Xenotransplantation.

Hawthorne WJ, Cowan PJ, Bühler LH, Yi S, Bottino R, Pierson RN 3rd, Ahn C, Azimzadeh A, Cozzi E, Gianello P, Lakey JRT, Luo M, Miyagawa S, Mohiuddin MM, Park CG, Schuurman HJ, Scobie L, Sykes M, Tector J, Tönjes RR, Wolf E, Nuñez JR, Wang W.

Xenotransplantation. 2019 Mar;26(2):e12513. doi: 10.1111/xen.12513. Epub 2019 Apr 13. No abstract available.

PMID:
30980428
9.

Crossreactive public TCR sequences undergo positive selection in the human thymic repertoire.

Khosravi-Maharlooei M, Obradovic A, Misra A, Motwani K, Holzl M, Seay HR, DeWolf S, Nauman G, Danzl N, Li H, Ho SH, Winchester R, Shen Y, Brusko TM, Sykes M.

J Clin Invest. 2019 Mar 28;129(6):2446-2462. doi: 10.1172/JCI124358.

10.

A critical review of the specifications and performance of antibody and DNA-based methods for detection and quantification of allergens in foods.

Senyuva HZ, Jones IB, Sykes M, Baumgartner S.

Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2019 Apr;36(4):507-547. doi: 10.1080/19440049.2019.1579927. Epub 2019 Mar 11. Review.

PMID:
30856064
11.

Microenvironment control of porphyrin binding, organization, and function in peptide nanofiber assemblies.

Solomon LA, Wood AR, Sykes ME, Diroll BT, Wiederrecht GP, Schaller RD, Fry HC.

Nanoscale. 2019 Mar 21;11(12):5412-5421. doi: 10.1039/c8nr09556f.

PMID:
30855041
12.

Generation and persistence of human tissue-resident memory T cells in lung transplantation.

Snyder ME, Finlayson MO, Connors TJ, Dogra P, Senda T, Bush E, Carpenter D, Marboe C, Benvenuto L, Shah L, Robbins H, Hook JL, Sykes M, D'Ovidio F, Bacchetta M, Sonett JR, Lederer DJ, Arcasoy S, Sims PA, Farber DL.

Sci Immunol. 2019 Mar 8;4(33). pii: eaav5581. doi: 10.1126/sciimmunol.aav5581.

PMID:
30850393
13.

The 1997 Mars Pathfinder Spacecraft Landing Site: Spillover Deposits from an Early Mars Inland Sea.

Rodriguez JAP, Baker VR, Liu T, Zarroca M, Travis B, Hui T, Komatsu G, Berman DC, Linares R, Sykes MV, Banks ME, Kargel JS.

Sci Rep. 2019 Feb 25;9(1):4045. doi: 10.1038/s41598-019-39632-1.

14.

Direct CDKN2 Modulation of CDK4 Alters Target Engagement of CDK4 Inhibitor Drugs.

Green JL, Okerberg ES, Sejd J, Palafox M, Monserrat L, Alemayehu S, Wu J, Sykes M, Aban A, Serra V, Nomanbhoy T.

Mol Cancer Ther. 2019 Apr;18(4):771-779. doi: 10.1158/1535-7163.MCT-18-0755. Epub 2019 Mar 5.

PMID:
30837298
15.

Posttransplant Hemophagocytic Lymphohistiocytosis Driven by Myeloid Cytokines and Vicious Cycles of T-Cell and Macrophage Activation in Humanized Mice.

Yoshihara S, Li Y, Xia J, Danzl N, Sykes M, Yang YG.

Front Immunol. 2019 Feb 13;10:186. doi: 10.3389/fimmu.2019.00186. eCollection 2019.

16.

Twenty Year Follow Up of Histocompatibility Leukocyte Antigen-Matched Kidney and Bone Marrow Co-Transplantation for Multiple Myeloma with End Stage Renal Disease: Lessons Learned.

Spitzer TR, Tolkoff-Rubin N, Cosimi B, McAfee S, Dey BR, Chen YB, Delmonico F, Sykes M, Sachs DH, Kawai T.

Transplantation. 2019 Feb 12. doi: 10.1097/TP.0000000000002669. [Epub ahead of print]

PMID:
30801529
17.

Characterization, biology, and expansion of regulatory T cells in the Cynomolgus macaque for preclinical studies.

Alonso-Guallart P, Zitsman JS, Stern J, Kofman SB, Woodland D, Ho SH, Sondermeijer HP, Bühler L, Griesemer A, Sykes M, Duran-Struuck R.

Am J Transplant. 2019 Aug;19(8):2186-2198. doi: 10.1111/ajt.15313. Epub 2019 Mar 29.

PMID:
30768842
18.

Tripeptide analogues of MG132 as protease inhibitors.

Pehere AD, Nguyen S, Garlick SK, Wilson DW, Hudson I, Sykes MJ, Morton JD, Abell AD.

Bioorg Med Chem. 2019 Jan 15;27(2):436-441. doi: 10.1016/j.bmc.2018.12.022. Epub 2018 Dec 14.

PMID:
30581047
19.

Molecular Modeling Approaches for the Prediction of Selected Pharmacokinetic Properties.

Petito ES, Foster DJR, Ward MB, Sykes MJ.

Curr Top Med Chem. 2018;18(26):2230-2238. doi: 10.2174/1568026619666181220105726. Review.

PMID:
30569859
20.

Human Intestinal Allografts Contain Functional Hematopoietic Stem and Progenitor Cells that Are Maintained by a Circulating Pool.

Fu J, Zuber J, Martinez M, Shonts B, Obradovic A, Wang H, Lau SP, Xia A, Waffarn EE, Frangaj K, Savage TM, Simpson MT, Yang S, Guo XV, Miron M, Senda T, Rogers K, Rahman A, Ho SH, Shen Y, Griesemer A, Farber DL, Kato T, Sykes M.

Cell Stem Cell. 2019 Feb 7;24(2):227-239.e8. doi: 10.1016/j.stem.2018.11.007. Epub 2018 Nov 29.

PMID:
30503142
21.

Design, Synthesis, and Biological Evaluation of 2-Nitroimidazopyrazin-one/-es with Antitubercular and Antiparasitic Activity.

Jarrad AM, Ang CW, Debnath A, Hahn HJ, Woods K, Tan L, Sykes ML, Jones AJ, Pelingon R, Butler MS, Avery VM, West NP, Karoli T, Blaskovich MAT, Cooper MA.

J Med Chem. 2018 Dec 27;61(24):11349-11371. doi: 10.1021/acs.jmedchem.8b01578. Epub 2018 Dec 11.

22.

Early expansion of donor-specific Tregs in tolerant kidney transplant recipients.

Savage TM, Shonts BA, Obradovic A, Dewolf S, Lau S, Zuber J, Simpson MT, Berglund E, Fu J, Yang S, Ho SH, Tang Q, Turka LA, Shen Y, Sykes M.

JCI Insight. 2018 Nov 15;3(22). pii: 124086. doi: 10.1172/jci.insight.124086.

23.

Quantifying size and diversity of the human T cell alloresponse.

DeWolf S, Grinshpun B, Savage T, Lau SP, Obradovic A, Shonts B, Yang S, Morris H, Zuber J, Winchester R, Sykes M, Shen Y.

JCI Insight. 2018 Aug 9;3(15). pii: 121256. doi: 10.1172/jci.insight.121256. eCollection 2018 Aug 9.

24.

Systematic review of methods for quantifying teamwork in the operating theatre.

Li N, Marshall D, Sykes M, McCulloch P, Shalhoub J, Maruthappu M.

BJS Open. 2018 Feb 15;2(2):42-51. doi: 10.1002/bjs5.40. eCollection 2018 Apr. Review.

25.

Material Dimensionality Effects on Electron Transfer Rates Between CsPbBr3 and CdSe Nanoparticles.

Brumberg A, Diroll BT, Nedelcu G, Sykes ME, Liu Y, Harvey SM, Wasielewski MR, Kovalenko MV, Schaller RD.

Nano Lett. 2018 Aug 8;18(8):4771-4776. doi: 10.1021/acs.nanolett.8b01238. Epub 2018 Jul 6.

PMID:
29944381
26.

IXA Honorary Member Lecture, 2017: The long and winding road to tolerance.

Sykes M.

Xenotransplantation. 2018 May;25(3):e12419. doi: 10.1111/xen.12419. Review.

27.

Hypercholesterolemia induces T cell expansion in humanized immune mice.

Proto JD, Doran AC, Subramanian M, Wang H, Zhang M, Sozen E, Rymond CC, Kuriakose G, D'Agati V, Winchester R, Sykes M, Yang YG, Tabas I.

J Clin Invest. 2018 Jun 1;128(6):2370-2375. doi: 10.1172/JCI97785. Epub 2018 Apr 30.

28.

The impact of right ventricular pressure and function on survival in patients with pulmonary vein stenosis.

Sykes MC, Ireland C, McSweeney JE, Rosenholm E, Andren KG, Kulik TJ.

Pulm Circ. 2018 Apr-Jun;8(2):2045894018776894. doi: 10.1177/2045894018776894. Epub 2018 Apr 30.

29.

The impact of improving teamwork on patient outcomes in surgery: A systematic review.

Sun R, Marshall DC, Sykes MC, Maruthappu M, Shalhoub J.

Int J Surg. 2018 May;53:171-177. doi: 10.1016/j.ijsu.2018.03.044. Epub 2018 Mar 22. Review.

30.
31.

Prevalence of axial spondyloarthritis in patients with acute anterior uveitis: a cross-sectional study utilising MRI.

Sykes MP, Hamilton L, Jones C, Gaffney K.

RMD Open. 2018 Feb 24;4(1):e000553. doi: 10.1136/rmdopen-2017-000553. eCollection 2018.

32.

GalT-KO pig lungs are highly susceptible to acute vascular rejection in baboons, which may be mitigated by transgenic expression of hCD47 on porcine blood vessels.

Watanabe H, Sahara H, Nomura S, Tanabe T, Ekanayake-Alper DK, Boyd LK, Louras NJ, Asfour A, Danton MA, Ho SH, Arn SJ, Hawley RJ, Shimizu A, Nagayasu T, Ayares D, Lorber MI, Sykes M, Sachs DH, Yamada K.

Xenotransplantation. 2018 Sep;25(5):e12391. doi: 10.1111/xen.12391. Epub 2018 Mar 12.

PMID:
29527745
33.

Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization.

Fuchs A, Gliwiński M, Grageda N, Spiering R, Abbas AK, Appel S, Bacchetta R, Battaglia M, Berglund D, Blazar B, Bluestone JA, Bornhäuser M, Ten Brinke A, Brusko TM, Cools N, Cuturi MC, Geissler E, Giannoukakis N, Gołab K, Hafler DA, van Ham SM, Hester J, Hippen K, Di Ianni M, Ilic N, Isaacs J, Issa F, Iwaszkiewicz-Grześ D, Jaeckel E, Joosten I, Klatzmann D, Koenen H, van Kooten C, Korsgren O, Kretschmer K, Levings M, Marek-Trzonkowska NM, Martinez-Llordella M, Miljkovic D, Mills KHG, Miranda JP, Piccirillo CA, Putnam AL, Ritter T, Roncarolo MG, Sakaguchi S, Sánchez-Ramón S, Sawitzki B, Sofronic-Milosavljevic L, Sykes M, Tang Q, Vives-Pi M, Waldmann H, Witkowski P, Wood KJ, Gregori S, Hilkens CMU, Lombardi G, Lord P, Martinez-Caceres EM, Trzonkowski P.

Front Immunol. 2018 Jan 15;8:1844. doi: 10.3389/fimmu.2017.01844. eCollection 2017.

34.

HSC extrinsic sex-related and intrinsic autoimmune disease-related human B-cell variation is recapitulated in humanized mice.

Borsotti C, Danzl NM, Nauman G, Hölzl MA, French C, Chavez E, Khosravi-Maharlooei M, Glauzy S, Delmotte FR, Meffre E, Savage DG, Campbell SR, Goland R, Greenberg E, Bi J, Satwani P, Yang S, Bathon J, Winchester R, Sykes M.

Blood Adv. 2017 Oct 13;1(23):2007-2018. doi: 10.1182/bloodadvances.2017006932. eCollection 2017 Oct 24.

35.

Open splenectomy for Varicella zoster induced spontaneous splenic rupture.

Sykes MC, Azhar B, John L, Bokhari S.

Int J Surg Case Rep. 2018;42:237-241. doi: 10.1016/j.ijscr.2017.11.070. Epub 2017 Dec 24.

36.

Immune monitoring of transplant patients in transient mixed chimerism tolerance trials.

Sykes M.

Hum Immunol. 2018 May;79(5):334-342. doi: 10.1016/j.humimm.2017.12.011. Epub 2017 Dec 28. Review.

37.

Differential Wavevector Distribution of Surface-Enhanced Raman Scattering and Fluorescence in a Film-Coupled Plasmonic Nanowire Cavity.

Vasista AB, Jog H, Heilpern T, Sykes ME, Tiwari S, Sharma DK, Chaubey SK, Wiederrecht GP, Gray SK, Kumar GVP.

Nano Lett. 2018 Jan 10;18(1):650-655. doi: 10.1021/acs.nanolett.7b05080. Epub 2017 Dec 21.

PMID:
29244518
38.

Publisher Correction: Enhanced generation and anisotropic Coulomb scattering of hot electrons in an ultra-broadband plasmonic nanopatch metasurface.

Sykes ME, Stewart JW, Akselrod GM, Kong XT, Wang Z, Gosztola DJ, Martinson ABF, Rosenmann D, Mikkelsen MH, Govorov AO, Wiederrecht GP.

Nat Commun. 2017 Dec 12;8(1):2135. doi: 10.1038/s41467-017-02106-x.

39.

When is audit and feedback effective in dementia care? A systematic review.

Sykes MJ, McAnuff J, Kolehmainen N.

Int J Nurs Stud. 2018 Mar;79:27-35. doi: 10.1016/j.ijnurstu.2017.10.013. Epub 2017 Nov 10. Review.

PMID:
29128686
40.

Enhanced generation and anisotropic Coulomb scattering of hot electrons in an ultra-broadband plasmonic nanopatch metasurface.

Sykes ME, Stewart JW, Akselrod GM, Kong XT, Wang Z, Gosztola DJ, Martinson ABF, Rosenmann D, Mikkelsen MH, Govorov AO, Wiederrecht GP.

Nat Commun. 2017 Oct 17;8(1):986. doi: 10.1038/s41467-017-01069-3. Erratum in: Nat Commun. 2017 Dec 12;8(1):2135.

41.

Screening a Natural Product-Based Library against Kinetoplastid Parasites.

Zulfiqar B, Jones AJ, Sykes ML, Shelper TB, Davis RA, Avery VM.

Molecules. 2017 Oct 12;22(10). pii: E1715. doi: 10.3390/molecules22101715.

42.

Tolerance in xenotransplantation.

Yamada K, Sykes M, Sachs DH.

Curr Opin Organ Transplant. 2017 Dec;22(6):522-528. doi: 10.1097/MOT.0000000000000466. Review.

43.

Novel H-shunt Venovenous Bypass for Liver Transplantation in Cynomolgus Macaques.

Kato Y, Griesemer AD, Wu A, Sondermeijer HP, Weiner JI, Duran-Struuck R, Martinez M, Slate AR, Romanov A, Lefkowitch JH, Sykes M, Kato T.

Comp Med. 2017 Oct 1;67(5):436-441.

44.

β-Cell Replacement in Mice Using Human Type 1 Diabetes Nuclear Transfer Embryonic Stem Cells.

Sui L, Danzl N, Campbell SR, Viola R, Williams D, Xing Y, Wang Y, Phillips N, Poffenberger G, Johannesson B, Oberholzer J, Powers AC, Leibel RL, Chen X, Sykes M, Egli D.

Diabetes. 2018 Jan;67(1):26-35. doi: 10.2337/db17-0120. Epub 2017 Sep 20.

45.

Pseudoaneurysm complicating right ventricle-to-pulmonary artery conduit surgery: Incidence and risk factors.

Sykes MC, Nathan M, Sanders SP, Gauvreau K, Pigula FA, Rhodes J.

J Thorac Cardiovasc Surg. 2017 Dec;154(6):2046-2049. doi: 10.1016/j.jtcvs.2017.08.014. Epub 2017 Aug 24.

PMID:
28919137
46.

Type 1 diabetes induction in humanized mice.

Tan S, Li Y, Xia J, Jin CH, Hu Z, Duinkerken G, Li Y, Khosravi Maharlooei M, Chavez E, Nauman G, Danzl N, Nakayama M, Roep BO, Sykes M, Yang YG.

Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):10954-10959. doi: 10.1073/pnas.1710415114. Epub 2017 Sep 5.

48.

Mechanisms of Mixed Chimerism-Based Transplant Tolerance.

Zuber J, Sykes M.

Trends Immunol. 2017 Nov;38(11):829-843. doi: 10.1016/j.it.2017.07.008. Epub 2017 Aug 18. Review.

49.

Tailorable Exciton Transport in Doped Peptide-Amphiphile Assemblies.

Solomon LA, Sykes ME, Wu YA, Schaller RD, Wiederrecht GP, Fry HC.

ACS Nano. 2017 Sep 26;11(9):9112-9118. doi: 10.1021/acsnano.7b03867. Epub 2017 Aug 29.

PMID:
28817256
50.

Screening the Medicines for Malaria Venture Pathogen Box across Multiple Pathogens Reclassifies Starting Points for Open-Source Drug Discovery.

Duffy S, Sykes ML, Jones AJ, Shelper TB, Simpson M, Lang R, Poulsen SA, Sleebs BE, Avery VM.

Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e00379-17. doi: 10.1128/AAC.00379-17. Print 2017 Sep.

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