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Use of a novel atlas for muscles of mastication to reduce inter observer variability in head and neck radiotherapy contouring.

Hague C, Beasley W, Dixon L, Gaito S, Garcez K, Green A, Lee LW, Maranzano M, McPartlin A, Mistry H, Mullan D, Sykes AJ, Thomson D, Van Herk M, West CM, Slevin N.

Radiother Oncol. 2018 Nov 9. pii: S0167-8140(18)33554-0. doi: 10.1016/j.radonc.2018.10.030. [Epub ahead of print]


Genetic Variation in the Psychiatric Risk Gene CACNA1C Modulates Reversal Learning Across Species.

Sykes L, Haddon J, Lancaster TM, Sykes A, Azzouni K, Ihssen N, Moon AL, Lin TE, Linden DE, Owen MJ, O'Donovan MC, Humby T, Wilkinson LS, Thomas KL, Hall J.

Schizophr Bull. 2018 Oct 10. doi: 10.1093/schbul/sby146. [Epub ahead of print]


A unified personal protective equipment ensemble for clinical response to possible high consequence infectious diseases: A consensus document on behalf of the HCID programme.

Poller B, Tunbridge A, Hall S, Beadsworth M, Jacobs M, Peters E, Schmid ML, Sykes A, Poran V, Gent N, Evans C, Crook B; High Consequence Infectious Diseases Project Working Group.

J Infect. 2018 Dec;77(6):496-502. doi: 10.1016/j.jinf.2018.08.016. Epub 2018 Aug 31.


Prospective Pilot Evaluation of Radiologists and Computer-aided Pulmonary Nodule Detection on Ultra-low-Dose CT With Tin Filtration.

Takahashi EA, Koo CW, White DB, Lindell RM, Sykes AG, Levin DL, Kuzo RS, Wolf M, Bogoni L, Carter RE, McCollough CH, Fletcher JG.

J Thorac Imaging. 2018 Nov;33(6):396-401. doi: 10.1097/RTI.0000000000000348.


Incorporating Bereaved Parents as Faculty Facilitators and Educators in Teaching Principles of Palliative and End-of-Life Care.

Snaman JM, Kaye EC, Spraker-Perlman H, Levine D, Clark L, Wilcox R, Barnett B, Sykes A, Lu Z, Cunningham MJ, Baker JN.

Am J Hosp Palliat Care. 2018 Dec;35(12):1518-1525. doi: 10.1177/1049909118786875. Epub 2018 Jul 16.


An Exploratory Study of Daprodustat in Erythropoietin-Hyporesponsive Subjects.

Cizman B, Sykes AP, Paul G, Zeig S, Cobitz AR.

Kidney Int Rep. 2018 Mar 3;3(4):841-850. doi: 10.1016/j.ekir.2018.02.009. eCollection 2018 Jul.


Clinical Characteristics of Children and Adolescents Undergoing Hematopoietic Cell Transplantation Who Develop Oral Mucositis.

Donohoe C, Bosi JK, Sykes A, Lu Z, Mandrell B.

Oncol Nurs Forum. 2018 Jul 2;45(4):457-462. doi: 10.1188/18.ONF.457-462.


The brain-penetrant clinical ATM inhibitor AZD1390 radiosensitizes and improves survival of preclinical brain tumor models.

Durant ST, Zheng L, Wang Y, Chen K, Zhang L, Zhang T, Yang Z, Riches L, Trinidad AG, Fok JHL, Hunt T, Pike KG, Wilson J, Smith A, Colclough N, Reddy VP, Sykes A, Janefeldt A, Johnström P, Varnäs K, Takano A, Ling S, Orme J, Stott J, Roberts C, Barrett I, Jones G, Roudier M, Pierce A, Allen J, Kahn J, Sule A, Karlin J, Cronin A, Chapman M, Valerie K, Illingworth R, Pass M.

Sci Adv. 2018 Jun 20;4(6):eaat1719. doi: 10.1126/sciadv.aat1719. eCollection 2018 Jun.


Long term patient reported swallowing function following chemoradiotherapy for oropharyngeal carcinoma.

Dixon L, Ramasamy S, Cardale K, Dyker K, Garcez K, Lee LW, McPartlin A, Murray P, Sen M, Slevin N, Sykes A, Prestwich R, Thomson D.

Radiother Oncol. 2018 Sep;128(3):452-458. doi: 10.1016/j.radonc.2018.06.014. Epub 2018 Jun 21.


Complete Substrate Inhibition of Cytochrome P450 2C8 by AZD9496, an Oral Selective Estrogen Receptor Degrader.

Bapiro TE, Sykes A, Martin S, Davies M, Yates JWT, Hoch M, Rollison HE, Jones B.

Drug Metab Dispos. 2018 Sep;46(9):1268-1276. doi: 10.1124/dmd.118.081539. Epub 2018 Jun 19.


Rapid decrease of serum alpha-fetoprotein and tumor volume predicts outcome in children with hepatoblastoma treated with neoadjuvant chemotherapy.

Nguyen R, McCarville MB, Sykes A, Mao S, Wu J, Langham MR Jr, Furman WL.

Int J Clin Oncol. 2018 May 9. doi: 10.1007/s10147-018-1285-4. [Epub ahead of print]


Predictors of Location of Death for Children with Cancer Enrolled on a Palliative Care Service.

Kaye EC, DeMarsh S, Gushue CA, Jerkins J, Sykes A, Lu Z, Snaman JM, Blazin LJ, Johnson LM, Levine DR, Ray Morrison R, Baker JN.

Oncologist. 2018 May 4. pii: theoncologist.2017-0650. doi: 10.1634/theoncologist.2017-0650. [Epub ahead of print]


Prospective evaluation of relationships between radiotherapy dose to masticatory apparatus and trismus.

Hague C, Beasley W, Garcez K, Lee LW, McPartlin A, McWilliam A, Ryder D, Sykes AJ, Thomson D, van Herk M, West C, Slevin NJ.

Acta Oncol. 2018 Aug;57(8):1038-1042. doi: 10.1080/0284186X.2018.1459047. Epub 2018 Apr 9.


Predictors of Late Palliative Care Referral in Children With Cancer.

Kaye EC, Jerkins J, Gushue CA, DeMarsh S, Sykes A, Lu Z, Snaman JM, Blazin L, Johnson LM, Levine DR, Morrison RR, Baker JN.

J Pain Symptom Manage. 2018 Jun;55(6):1550-1556. doi: 10.1016/j.jpainsymman.2018.01.021. Epub 2018 Feb 8.


Comparison of Resting Energy Expenditure Assessment in Pediatric Oncology Patients.

Ringwald-Smith K, Hobar A, Flowers C, Badgett K, Williams-Hooker R, Roach RR, Sykes A, Lu Z, Mackert P, Mandrell BN.

Nutr Clin Pract. 2018 Apr;33(2):224-231. doi: 10.1002/ncp.10002. Epub 2018 Feb 2.


Mast cells increase adult neural precursor proliferation and differentiation but this potential is not realized in vivo under physiological conditions.

Wasielewska JM, Grönnert L, Rund N, Donix L, Rust R, Sykes AM, Hoppe A, Roers A, Kempermann G, Walker TL.

Sci Rep. 2017 Dec 19;7(1):17859. doi: 10.1038/s41598-017-18184-2.


Taxane, platinum and 5-FU prior to chemoradiotherapy benefits patients with stage IV neck node-positive head and neck cancer and a good performance status.

Lowe NM, Bernstein JM, Mais K, Garcez K, Lee LW, Sykes A, Thomson DJ, Homer JJ, West CM, Slevin NJ.

J Cancer Res Clin Oncol. 2018 Feb;144(2):389-401. doi: 10.1007/s00432-017-2553-9. Epub 2017 Dec 8.


Illness and end-of-life experiences of children with cancer who receive palliative care.

Kaye EC, Gushue CA, DeMarsh S, Jerkins J, Sykes A, Lu Z, Snaman JM, Blazin L, Johnson LM, Levine DR, Morrison RR, Baker JN.

Pediatr Blood Cancer. 2018 Apr;65(4). doi: 10.1002/pbc.26895. Epub 2017 Dec 8.


The flip-flop fungus sign: an FDG PET/CT sign of benignity.

Nagelschneider AA, Broski SM, Holland WP, Midthun DE, Sykes AM, Lowe VJ, Peller PJ, Johnson GB.

Am J Nucl Med Mol Imaging. 2017 Nov 1;7(5):212-217. eCollection 2017.


The Effectiveness of Trivalent Inactivated Influenza Vaccine in Children with Acute Leukemia.

Sykes A, Gerhardt E, Tang L, Adderson EE.

J Pediatr. 2017 Dec;191:218-224.e1. doi: 10.1016/j.jpeds.2017.08.071.


Clinical Characteristics of Intravenous PEG-Asparaginase Hypersensitivity Reactions in Patients Undergoing Treatment for Acute Lymphoblastic Leukemia [Formula: see text].

Browne EK, Moore C, Sykes A, Lu Z, Jeha S, Mandrell BN.

J Pediatr Oncol Nurs. 2018 Mar/Apr;35(2):103-109. doi: 10.1177/1043454217741868. Epub 2017 Nov 21.


Conventional fractionation should not be the standard of care for T2 glottic cancer.

Dixon LM, Douglas CM, Shaukat SI, Garcez K, Lee LW, Sykes AJ, Thomson D, Slevin NJ.

Radiat Oncol. 2017 Nov 14;12(1):178. doi: 10.1186/s13014-017-0915-8.


Treatment intensity and symptom burden in hospitalized adolescent and young adult hematopoietic cell transplant recipients at the end of life.

Snaman JM, Talleur AC, Lu J, Levine DR, Kaye EC, Sykes A, Lu Z, Triplett BM, Baker JN.

Bone Marrow Transplant. 2018 Jan;53(1):84-90. doi: 10.1038/bmt.2017.187. Epub 2017 Nov 13.


Prevalence, risk factors, and response to treatment for hypersomnia of central origin in survivors of childhood brain tumors.

Khan RB, Merchant TE, Sadighi ZS, Bello MS, Lu Z, Sykes A, Wise MS, Crabtree VM, Zabrowski J, Simmons A, Clark ME, Mandrell BN.

J Neurooncol. 2018 Jan;136(2):379-384. doi: 10.1007/s11060-017-2662-y. Epub 2017 Nov 8.


Ninety Day Mortality After Radical Radiotherapy for Head and Neck Cancer.

Dixon L, Garcez K, Lee LW, Sykes A, Slevin N, Thomson D.

Clin Oncol (R Coll Radiol). 2017 Dec;29(12):835-840. doi: 10.1016/j.clon.2017.08.005. Epub 2017 Sep 13.


Evaluation of a fever-management algorithm in a pediatric cancer center in a low-resource setting.

Mukkada S, Smith CK, Aguilar D, Sykes A, Tang L, Dolendo M, Caniza MA.

Pediatr Blood Cancer. 2018 Feb;65(2). doi: 10.1002/pbc.26790. Epub 2017 Sep 12.


Rhinovirus induction of fractalkine (CX3CL1) in airway and peripheral blood mononuclear cells in asthma.

Upton N, Jackson DJ, Nikonova AA, Hingley-Wilson S, Khaitov M, Del Rosario A, Traub S, Trujillo-Torralbo MB, Habibi M, Elkin SL, Kon OM, Edwards MR, Mallia P, Footitt J, Macintyre J, Stanciu LA, Johnston SL, Sykes A.

PLoS One. 2017 Aug 31;12(8):e0183864. doi: 10.1371/journal.pone.0183864. eCollection 2017.


Retinal cell death dependent reactive proliferative gliosis in the mouse retina.

Sardar Pasha SPB, Münch R, Schäfer P, Oertel P, Sykes AM, Zhu Y, Karl MO.

Sci Rep. 2017 Aug 25;7(1):9517. doi: 10.1038/s41598-017-09743-8.


The bereavement experience of adolescents and early young adults with cancer: Peer and parental loss due to death is associated with increased risk of adverse psychological outcomes.

Johnson LM, Torres C, Sykes A, Gibson DV, Baker JN.

PLoS One. 2017 Aug 23;12(8):e0181024. doi: 10.1371/journal.pone.0181024. eCollection 2017.


Assessment of the Target Engagement and D-Serine Biomarker Profiles of the D-Amino Acid Oxidase Inhibitors Sodium Benzoate and PGM030756.

Howley E, Bestwick M, Fradley R, Harrison H, Leveridge M, Okada K, Fieldhouse C, Farnaby W, Canning H, Sykes AP, Merchant K, Hazel K, Kerr C, Kinsella N, Walsh L, Livermore DG, Hoffman I, Ellery J, Mitchell P, Patel T, Carlton M, Barnes M, Miller DJ.

Neurochem Res. 2017 Nov;42(11):3279-3288. doi: 10.1007/s11064-017-2367-9. Epub 2017 Aug 5.


The Digestive Tract of Cephalopods: a Neglected Topic of Relevance to Animal Welfare in the Laboratory and Aquaculture.

Sykes AV, Almansa E, Cooke GM, Ponte G, Andrews PLR.

Front Physiol. 2017 Jul 17;8:492. doi: 10.3389/fphys.2017.00492. eCollection 2017. Review.


Nonrhabdomyosarcoma soft tissue sarcoma (NRSTS) in pediatric and young adult patients: Results from a prospective study using limited-margin radiotherapy.

Tinkle CL, Fernandez-Pineda I, Sykes A, Lu Z, Hua CH, Neel MD, Bahrami A, Shulkin BL, Kaste SC, Pappo A, Spunt SL, Krasin MJ.

Cancer. 2017 Nov 15;123(22):4419-4429. doi: 10.1002/cncr.30793. Epub 2017 Jul 31.


The Digestive Tract of Cephalopods: Toward Non-invasive In vivo Monitoring of Its Physiology.

Ponte G, Sykes AV, Cooke GM, Almansa E, Andrews PLR.

Front Physiol. 2017 Jun 19;8:403. doi: 10.3389/fphys.2017.00403. eCollection 2017.


Hypoxic Induced Decrease in Oxygen Consumption in Cuttlefish (Sepia officinalis) Is Associated with Minor Increases in Mantle Octopine but No Changes in Markers of Protein Turnover.

Capaz JC, Tunnah L, MacCormack TJ, Lamarre SG, Sykes AV, Driedzic WR.

Front Physiol. 2017 May 26;8:344. doi: 10.3389/fphys.2017.00344. eCollection 2017.


A Population Pharmacokinetic and Pharmacodynamic Analysis of Abemaciclib in a Phase I Clinical Trial in Cancer Patients.

Tate SC, Sykes AK, Kulanthaivel P, Chan EM, Turner PK, Cronier DM.

Clin Pharmacokinet. 2018 Mar;57(3):335-344. doi: 10.1007/s40262-017-0559-8.


Measurable Supratentorial White Matter Volume Changes in Patients with Diffuse Intrinsic Pontine Glioma Treated with an Anti-Vascular Endothelial Growth Factor Agent, Steroids, and Radiation.

Svolos P, Reddick WE, Edwards A, Sykes A, Li Y, Glass JO, Patay Z.

AJNR Am J Neuroradiol. 2017 Jun;38(6):1235-1241. doi: 10.3174/ajnr.A5159. Epub 2017 Apr 20.


Patients' and Parents' Needs, Attitudes, and Perceptions About Early Palliative Care Integration in Pediatric Oncology.

Levine DR, Mandrell BN, Sykes A, Pritchard M, Gibson D, Symons HJ, Wendler D, Baker JN.

JAMA Oncol. 2017 Sep 1;3(9):1214-1220. doi: 10.1001/jamaoncol.2017.0368.


Estimation of Observer Performance for Reduced Radiation Dose Levels in CT: Eliminating Reduced Dose Levels That Are Too Low Is the First Step.

Fletcher JG, Yu L, Fidler JL, Levin DL, DeLone DR, Hough DM, Takahashi N, Venkatesh SK, Sykes AG, White D, Lindell RM, Kotsenas AL, Campeau NG, Lehman VT, Bartley AC, Leng S, Holmes DR 3rd, Toledano AY, Carter RE, McCollough CH.

Acad Radiol. 2017 Jul;24(7):876-890. doi: 10.1016/j.acra.2016.12.017. Epub 2017 Mar 2.


Integrating next-generation sequencing into pediatric oncology practice: An assessment of physician confidence and understanding of clinical genomics.

Johnson LM, Valdez JM, Quinn EA, Sykes AD, McGee RB, Nuccio R, Hines-Dowell SJ, Baker JN, Kesserwan C, Nichols KE, Mandrell BN.

Cancer. 2017 Jun 15;123(12):2352-2359. doi: 10.1002/cncr.30581. Epub 2017 Feb 13.


Electrochemotherapy in the treatment of metastatic malignant melanoma: a prospective cohort study by InspECT.

Kunte C, Letulé V, Gehl J, Dahlstroem K, Curatolo P, Rotunno R, Muir T, Occhini A, Bertino G, Powell B, Saxinger W, Lechner G, Liew SH, Pritchard-Jones R, Rutkowski P, Zdzienicki M, Mowatt D, Sykes AJ, Orlando A, Mitsala G, Rossi CR, Campana L, Brizio M, de Terlizzi F, Quaglino P, Odili J; InspECT (the International Network for Sharing Practices on Electrochemotherapy).

Br J Dermatol. 2017 Jun;176(6):1475-1485. doi: 10.1111/bjd.15340. Epub 2017 Apr 26.


Palliative Care Involvement Is Associated with Less Intensive End-of-Life Care in Adolescent and Young Adult Oncology Patients.

Snaman JM, Kaye EC, Lu JJ, Sykes A, Baker JN.

J Palliat Med. 2017 May;20(5):509-516. doi: 10.1089/jpm.2016.0451. Epub 2017 Jan 18.


Comparative study on fatty acid metabolism of early stages of two crustacean species: Artemia sp. metanauplii and Grapsus adscensionis zoeae, as live prey for marine animals.

Reis DB, Acosta NG, Almansa E, Navarro JC, Tocher DR, Andrade JP, Sykes AV, Rodríguez C.

Comp Biochem Physiol B Biochem Mol Biol. 2017 Feb;204:53-60. doi: 10.1016/j.cbpb.2016.11.002. Epub 2016 Nov 11.


Addition of the Fleischner Society Guidelines to Chest CT Examination Interpretive Reports Improves Adherence to Recommended Follow-up Care for Incidental Pulmonary Nodules.

McDonald JS, Koo CW, White D, Hartman TE, Bender CE, Sykes AG.

Acad Radiol. 2017 Mar;24(3):337-344. doi: 10.1016/j.acra.2016.08.026. Epub 2016 Oct 25.


Anisotropic Expansion of a Thermal Dipolar Bose Gas.

Tang Y, Sykes AG, Burdick NQ, DiSciacca JM, Petrov DS, Lev BL.

Phys Rev Lett. 2016 Oct 7;117(15):155301. Epub 2016 Oct 4.


Large airways nodularity secondary to tracheobronchopathia osteochondroplastica.

Corcoran JP, Wrightson JM, Moore AJ, Gleeson FV, Sykes A.

Thorax. 2017 Mar;72(3):288-289. doi: 10.1136/thoraxjnl-2016-209164. Epub 2016 Sep 28. No abstract available.


Going straight to the source: A pilot study of bereaved parent-facilitated communication training for pediatric subspecialty fellows.

Snaman JM, Kaye EC, Cunningham MJ, Sykes A, Levine DR, Mahoney D, Baker JN.

Pediatr Blood Cancer. 2017 Jan;64(1):156-162. doi: 10.1002/pbc.26089. Epub 2016 Sep 8.


Children with minimal chance for cure: parent proxy of the child's health-related quality of life and the effect on parental physical and mental health during treatment.

Mandrell BN, Baker J, Levine D, Gattuso J, West N, Sykes A, Gajjar A, Broniscer A.

J Neurooncol. 2016 Sep;129(2):373-81. doi: 10.1007/s11060-016-2187-9. Epub 2016 Jun 25.


Composition and metabolism of phospholipids in Octopus vulgaris and Sepia officinalis hatchlings.

Reis DB, Acosta NG, Almansa E, Tocher DR, Andrade JP, Sykes AV, Rodríguez C.

Comp Biochem Physiol B Biochem Mol Biol. 2016 Oct;200:62-8. doi: 10.1016/j.cbpb.2016.06.001. Epub 2016 Jun 4.


A review of current surgical practice in the operative treatment of proximal humeral fractures: Does the PROFHER trial demonstrate a need for change?

Dean BJ, Jones LD, Palmer AJ, Macnair RD, Brewer PE, Jayadev C, Wheelton AN, Ball DE, Nandra RS, Aujla RS, Sykes AE, Carr AJ.

Bone Joint Res. 2016 May;5(5):178-84. doi: 10.1302/2046-3758.55.2000596.


Enzymatic capacities of metabolic fuel use in cuttlefish (Sepia officinalis) and responses to food deprivation: insight into the metabolic organization and starvation survival strategy of cephalopods.

Speers-Roesch B, Callaghan NI, MacCormack TJ, Lamarre SG, Sykes AV, Driedzic WR.

J Comp Physiol B. 2016 Aug;186(6):711-25. doi: 10.1007/s00360-016-0991-3. Epub 2016 Apr 30.


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