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Evaluation of the Common Molecular Basis in Alzheimer's and Parkinson's Diseases.

Rana P, Franco EF, Rao Y, Syed K, Barh D, Azevedo V, Ramos RTJ, Ghosh P.

Int J Mol Sci. 2019 Jul 30;20(15). pii: E3730. doi: 10.3390/ijms20153730. Review.


A Case-Control Study on the Association Between Endoscopic ACE Grade of Adenoid Hypertrophy and Hearing Loss in Children and Its Impact on Speech and Language Development.

Syed KA, Naina P, Sebastian S, Varghese AM.

Indian J Otolaryngol Head Neck Surg. 2019 Jun;71(2):150-154. doi: 10.1007/s12070-018-1506-1. Epub 2018 Oct 3.


Pediatric tracheal dimensions on computed tomography and its correlation with tracheostomy tube sizes.

Naina P, Syed KA, Irodi A, John M, Varghese AM.

Laryngoscope. 2019 Jun 22. doi: 10.1002/lary.28141. [Epub ahead of print]


Distribution and Diversity of Cytochrome P450 Monooxygenases in the Fungal Class Tremellomycetes.

Akapo OO, Padayachee T, Chen W, Kappo AP, Yu JH, Nelson DR, Syed K.

Int J Mol Sci. 2019 Jun 13;20(12). pii: E2889. doi: 10.3390/ijms20122889.


The effects of depression, low back pain and comorbidities on pain after total knee arthroplasty for osteoarthritis are modified by sex.

Perruccio AV, Fitzpatrick J, Power JD, Gandhi R, Rampersaud YR, Mahomed NN, Davey JR, Syed K, Veillette C, Badley EM.

Arthritis Care Res (Hoboken). 2019 Jun 14. doi: 10.1002/acr.24002. [Epub ahead of print]


Intra-articular dislocation of patella with femoral impaction-A case report and review of literature.

Al Khalifa A, Syed K.

Int J Surg Case Rep. 2019;59:176-179. doi: 10.1016/j.ijscr.2019.05.041. Epub 2019 May 29.


Cytochrome P450 Monooxygenase CYP139 Family Involved in the Synthesis of Secondary Metabolites in 824 Mycobacterial Species.

Syed PR, Chen W, Nelson DR, Kappo AP, Yu JH, Karpoormath R, Syed K.

Int J Mol Sci. 2019 May 31;20(11). pii: E2690. doi: 10.3390/ijms20112690.


Bone Marrow Mesenchymal Stromal Cell Treatment in Patients with Osteoarthritis Results in Overall Improvement in Pain and Symptoms and Reduces Synovial Inflammation.

Chahal J, Gómez-Aristizábal A, Shestopaloff K, Bhatt S, Chaboureau A, Fazio A, Chisholm J, Weston A, Chiovitti J, Keating A, Kapoor M, Ogilvie-Harris DJ, Syed KA, Gandhi R, Mahomed NN, Marshall KW, Sussman MS, Naraghi AM, Viswanathan S.

Stem Cells Transl Med. 2019 Aug;8(8):746-757. doi: 10.1002/sctm.18-0183. Epub 2019 Apr 9.


Similarities, variations, and evolution of cytochrome P450s in Streptomyces versus Mycobacterium.

Senate LM, Tjatji MP, Pillay K, Chen W, Zondo NM, Syed PR, Mnguni FC, Chiliza ZE, Bamal HD, Karpoormath R, Khoza T, Mashele SS, Blackburn JM, Yu JH, Nelson DR, Syed K.

Sci Rep. 2019 Mar 8;9(1):3962. doi: 10.1038/s41598-019-40646-y.


Comprehensive Comparative Analysis of Cholesterol Catabolic Genes/Proteins in Mycobacterial Species.

van Wyk R, van Wyk M, Mashele SS, Nelson DR, Syed K.

Int J Mol Sci. 2019 Feb 27;20(5). pii: E1032. doi: 10.3390/ijms20051032.


Factors Associated With Opioid Use in Presurgical Knee, Hip, and Spine Osteoarthritis Patients.

Power JD, Perruccio AV, Gandhi R, Veillette C, Davey JR, Lewis SJ, Syed K, Mahomed NN, Rampersaud YR.

Arthritis Care Res (Hoboken). 2019 Jan 10. doi: 10.1002/acr.23831. [Epub ahead of print]


Sensing Properties of Oxidized Nanostructured Silicon Surface on Vaporized Molecules.

Baran N, Gebavi H, Mikac L, Ristić D, Gotić M, Syed KA, Ivanda M.

Sensors (Basel). 2019 Jan 1;19(1). pii: E119. doi: 10.3390/s19010119.


Paediatric tracheostomy: A modified technique and its outcomes, results from a South Indian tertiary care.

Syed KA, Naina P, Pokharel A, John M, Varghese AM.

Int J Pediatr Otorhinolaryngol. 2019 Mar;118:6-10. doi: 10.1016/j.ijporl.2018.12.007. Epub 2018 Dec 7.


Comparative Analyses of Cytochrome P450s and Those Associated with Secondary Metabolism in Bacillus Species.

Mthethwa BC, Chen W, Ngwenya ML, Kappo AP, Syed PR, Karpoormath R, Yu JH, Nelson DR, Syed K.

Int J Mol Sci. 2018 Nov 16;19(11). pii: E3623. doi: 10.3390/ijms19113623.


An integrated genomic analysis of anaplastic meningioma identifies prognostic molecular signatures.

Collord G, Tarpey P, Kurbatova N, Martincorena I, Moran S, Castro M, Nagy T, Bignell G, Maura F, Young MD, Berna J, Tubio JMC, McMurran CE, Young AMH, Sanders M, Noorani I, Price SJ, Watts C, Leipnitz E, Kirsch M, Schackert G, Pearson D, Devadass A, Ram Z, Collins VP, Allinson K, Jenkinson MD, Zakaria R, Syed K, Hanemann CO, Dunn J, McDermott MW, Kirollos RW, Vassiliou GS, Esteller M, Behjati S, Brazma A, Santarius T, McDermott U.

Sci Rep. 2018 Sep 10;8(1):13537. doi: 10.1038/s41598-018-31659-0.


Validation of a drooling questionnaire in Indian children with cerebral palsy.

Job A, Naina P, Syed KA, Thomas M, John M, Varghese AM.

Int J Pediatr Otorhinolaryngol. 2018 Sep;112:55-60. doi: 10.1016/j.ijporl.2018.06.029. Epub 2018 Jun 19.



Zito PM, Syed K.

StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2019 Jan-.
2018 Dec 19.


A randomized, observer-blinded, equivalence trial comparing two variations of Euvichol®, a bivalent killed whole-cell oral cholera vaccine, in healthy adults and children in the Philippines.

Russo P, Ligsay AD, Olveda R, Choi SK, Kim DR, Park JY, Park JY, Syed KA, Dey A, Kim YH, Lee SH, Kim J, Chon Y, Digilio L, Kim CW, Excler JL.

Vaccine. 2018 Jul 5;36(29):4317-4324. doi: 10.1016/j.vaccine.2018.05.102. Epub 2018 Jun 9.


Blooming of Unusual Cytochrome P450s by Tandem Duplication in the Pathogenic Fungus Conidiobolus coronatus.

Ngwenya ML, Chen W, Basson AK, Shandu JS, Yu JH, Nelson DR, Syed K.

Int J Mol Sci. 2018 Jun 9;19(6). pii: E1711. doi: 10.3390/ijms19061711.


Safety and immunogenicity of a Vi-DT typhoid conjugate vaccine: Phase I trial in Healthy Filipino adults and children.

Capeding MR, Teshome S, Saluja T, Syed KA, Kim DR, Park JY, Yang JS, Kim YH, Park J, Jo SK, Chon Y, Kothari S, Yang SY, Ham DS, Ryu JH, Hwang HS, Mun JH, Lynch JA, Kim JH, Kim H, Excler JL, Sahastrabuddhe S.

Vaccine. 2018 Jun 18;36(26):3794-3801. doi: 10.1016/j.vaccine.2018.05.038.


Comparative analyses and structural insights of the novel cytochrome P450 fusion protein family CYP5619 in Oomycetes.

Bamal HD, Chen W, Mashele SS, Nelson DR, Kappo AP, Mosa RA, Yu JH, Tuszynski JA, Syed K.

Sci Rep. 2018 Apr 26;8(1):6597. doi: 10.1038/s41598-018-25044-0.


Correction: Histone chaperone APLF regulates induction of pluripotency in murine fibroblasts (doi:10.1242/jcs.194035).

Syed KM, Joseph S, Mukherjee A, Majumder A, Teixeira JM, Dutta D, Pillai MR.

J Cell Sci. 2018 Apr 19;131(8). pii: jcs218842. doi: 10.1242/jcs.218842. No abstract available.


Clinical Study on Middle Ear Diseases in Children with Orofacial Clefts.

Kalaiarasi R, Syed KA, Vijayakumar C, Varghese AM, John M.

Cureus. 2018 Feb 8;10(2):e2175. doi: 10.7759/cureus.2175.


Enhanced expression of histone chaperone APLF associate with breast cancer.

Majumder A, Syed KM, Mukherjee A, Lankadasari MB, Azeez JM, Sreeja S, Harikumar KB, Pillai MR, Dutta D.

Mol Cancer. 2018 Mar 26;17(1):76. doi: 10.1186/s12943-018-0826-9.


Neuropathic pain in end-stage hip and knee osteoarthritis: differential associations with patient-reported pain at rest and pain on activity.

Power JD, Perruccio AV, Gandhi R, Veillette C, Davey JR, Syed K, Mahomed NN, Rampersaud YR.

Osteoarthritis Cartilage. 2018 Mar;26(3):363-369. doi: 10.1016/j.joca.2018.01.002. Epub 2018 Jan 9.


How to analyse the spatiotemporal tumour samples needed to investigate cancer evolution: A case study using paired primary and recurrent glioblastoma.

Droop A, Bruns A, Tanner G, Rippaus N, Morton R, Harrison S, King H, Ashton K, Syed K, Jenkinson MD, Brodbelt A, Chakrabarty A, Ismail A, Short S, Stead LF.

Int J Cancer. 2018 Apr 15;142(8):1620-1626. doi: 10.1002/ijc.31184. Epub 2017 Dec 14.


α-pyrones and their hydroxylated analogs as promising scaffolds against Mycobacterium tuberculosis.

Bhat ZS, Rather MA, Syed KY, Ahmad Z.

Future Med Chem. 2017 Nov;9(17):2053-2067. doi: 10.4155/fmc-2017-0116. Epub 2017 Oct 27. Review.


The Epstein-Barr Virus B-ZIP Protein Zta Recognizes Specific DNA Sequences Containing 5-Methylcytosine and 5-Hydroxymethylcytosine.

Tillo D, Ray S, Syed KS, Gaylor MR, He X, Wang J, Assad N, Durell SR, Porollo A, Weirauch MT, Vinson C.

Biochemistry. 2017 Nov 28;56(47):6200-6210. doi: 10.1021/acs.biochem.7b00741. Epub 2017 Nov 10.


In silico analysis of cytochrome P450 monooxygenases in chronic granulomatous infectious fungus Sporothrix schenckii: Special focus on CYP51.

Matowane RG, Wieteska L, Bamal HD, Kgosiemang IKR, Van Wyk M, Manume NA, Abdalla SMH, Mashele SS, Gront D, Syed K.

Biochim Biophys Acta Proteins Proteom. 2018 Jan;1866(1):166-177. doi: 10.1016/j.bbapap.2017.10.003. Epub 2017 Oct 5.


The compound (3-{5-[(2,5-dimethoxyphenyl)amino]-1,3,4-thiadiazolidin-2-yl}-5,8-methoxy-2H-chromen-2-one) inhibits the prion protein conversion from PrPC to PrPSc with lower IC50 in ScN2a cells.

Pagadala NS, Bjorndahl TC, Joyce M, Wishart DS, Syed K, Landi A.

Bioorg Med Chem. 2017 Oct 15;25(20):5875-5888. doi: 10.1016/j.bmc.2017.09.024. Epub 2017 Sep 19.


Prevalence of Distal Caries in Mandibular Second Molar Due to Impacted Third Molar.

Syed KB, Alshahrani FS, Alabsi WS, Alqahtani ZA, Hameed MS, Mustafa AB, Alam T.

J Clin Diagn Res. 2017 Mar;11(3):ZC28-ZC30. doi: 10.7860/JCDR/2017/18582.9509. Epub 2017 Mar 1.


Software for molecular docking: a review.

Pagadala NS, Syed K, Tuszynski J.

Biophys Rev. 2017 Apr;9(2):91-102. doi: 10.1007/s12551-016-0247-1. Epub 2017 Jan 16. Review.


Low birth weight is associated with impaired murine kidney development and function.

Barnett C, Nnoli O, Abdulmahdi W, Nesi L, Shen M, Zullo JA, Payne DL, Azar T, Dwivedi P, Syed K, Gromis J, Lipphardt M, Jules E, Maranda EL, Patel A, Rabadi MM, Ratliff BB.

Pediatr Res. 2017 Aug;82(2):340-348. doi: 10.1038/pr.2017.53. Epub 2017 May 31.


Barriers to accessing urethroplasty.

Consolo MJ, Syed KK, Robison C, McFadden J, Shalowitz DI, Brown GA, Sussman DO, Figler BD.

Rev Urol. 2016;18(4):188-193. doi: 10.3909/riu0731.


In silico strategies on prion pathogenic conversion and inhibition from PrPC -PrPSc.

Pagadala NS, Syed K, Bhat R.

Expert Opin Drug Discov. 2017 Mar;12(3):241-248. doi: 10.1080/17460441.2017.1287171. Epub 2017 Feb 2. Review.


5-Methylcytosine (5mC) and 5-Hydroxymethylcytosine (5hmC) Enhance the DNA Binding of CREB1 to the C/EBP Half-Site Tetranucleotide GCAA.

Syed KS, He X, Tillo D, Wang J, Durell SR, Vinson C.

Biochemistry. 2016 Dec 13;55(49):6940-6948. Epub 2016 Nov 29.


Histone chaperone APLF regulates induction of pluripotency in murine fibroblasts.

Syed KM, Joseph S, Mukherjee A, Majumder A, Teixeira JM, Dutta D, Pillai MR.

J Cell Sci. 2016 Dec 15;129(24):4576-4591. Epub 2016 Nov 14. Erratum in: J Cell Sci. 2018 Apr 19;131(8):.


Sublingual dermoid causing stertor in an infant.

Naina P, Syed KA, Koshy L, Mathews SS.

BMJ Case Rep. 2016 Sep 16;2016. pii: bcr2016217135. doi: 10.1136/bcr-2016-217135.


Molecular evolutionary dynamics of cytochrome P450 monooxygenases across kingdoms: Special focus on mycobacterial P450s.

Parvez M, Qhanya LB, Mthakathi NT, Kgosiemang IK, Bamal HD, Pagadala NS, Xie T, Yang H, Chen H, Theron CW, Monyaki R, Raselemane SC, Salewe V, Mongale BL, Matowane RG, Abdalla SM, Booi WI, van Wyk M, Olivier D, Boucher CE, Nelson DR, Tuszynski JA, Blackburn JM, Yu JH, Mashele SS, Chen W, Syed K.

Sci Rep. 2016 Sep 12;6:33099. doi: 10.1038/srep33099.


Congenital midnasal stenosis - A novel technique for management.

Syed KA, Raja K, Kolethekkat AA, Varghese AM, Al Abri R, Kurien M.

Int J Pediatr Otorhinolaryngol. 2016 Aug;87:117-20. doi: 10.1016/j.ijporl.2016.06.014. Epub 2016 Jun 7.


CD38 expression and complement inhibitors affect response and resistance to daratumumab therapy in myeloma.

Nijhof IS, Casneuf T, van Velzen J, van Kessel B, Axel AE, Syed K, Groen RW, van Duin M, Sonneveld P, Minnema MC, Zweegman S, Chiu C, Bloem AC, Mutis T, Lokhorst HM, Sasser AK, van de Donk NW.

Blood. 2016 Aug 18;128(7):959-70. doi: 10.1182/blood-2016-03-703439. Epub 2016 Jun 15.


"Post intubation Laryngeal injuries in a pediatric intensive care unit of tertiary hospital in India: A Fibreoptic endoscopic study".

Bharti B, Syed KA, Ebenezer K, Varghese AM, Kurien M.

Int J Pediatr Otorhinolaryngol. 2016 Jun;85:84-90. doi: 10.1016/j.ijporl.2016.03.025. Epub 2016 Mar 28.


Expansion of Signal Transduction Pathways in Fungi by Extensive Genome Duplication.

Corrochano LM, Kuo A, Marcet-Houben M, Polaino S, Salamov A, Villalobos-Escobedo JM, Grimwood J, Álvarez MI, Avalos J, Bauer D, Benito EP, Benoit I, Burger G, Camino LP, Cánovas D, Cerdá-Olmedo E, Cheng JF, Domínguez A, Eliáš M, Eslava AP, Glaser F, Gutiérrez G, Heitman J, Henrissat B, Iturriaga EA, Lang BF, Lavín JL, Lee SC, Li W, Lindquist E, López-García S, Luque EM, Marcos AT, Martin J, McCluskey K, Medina HR, Miralles-Durán A, Miyazaki A, Muñoz-Torres E, Oguiza JA, Ohm RA, Olmedo M, Orejas M, Ortiz-Castellanos L, Pisabarro AG, Rodríguez-Romero J, Ruiz-Herrera J, Ruiz-Vázquez R, Sanz C, Schackwitz W, Shahriari M, Shelest E, Silva-Franco F, Soanes D, Syed K, Tagua VG, Talbot NJ, Thon MR, Tice H, de Vries RP, Wiebenga A, Yadav JS, Braun EL, Baker SE, Garre V, Schmutz J, Horwitz BA, Torres-Martínez S, Idnurm A, Herrera-Estrella A, Gabaldón T, Grigoriev IV.

Curr Biol. 2016 Jun 20;26(12):1577-1584. doi: 10.1016/j.cub.2016.04.038. Epub 2016 May 26.


Daratumumab depletes CD38+ immune regulatory cells, promotes T-cell expansion, and skews T-cell repertoire in multiple myeloma.

Krejcik J, Casneuf T, Nijhof IS, Verbist B, Bald J, Plesner T, Syed K, Liu K, van de Donk NW, Weiss BM, Ahmadi T, Lokhorst HM, Mutis T, Sasser AK.

Blood. 2016 Jul 21;128(3):384-94. doi: 10.1182/blood-2015-12-687749. Epub 2016 May 24.


Systemic cobalt toxicity from total hip arthroplasties: review of a rare condition Part 2. measurement, risk factors, and step-wise approach to treatment.

Zywiel MG, Cherian JJ, Banerjee S, Cheung AC, Wong F, Butany J, Gilbert C, Overgaard C, Syed K, Jacobs JJ, Mont MA.

Bone Joint J. 2016 Jan;98-B(1):14-20. doi: 10.1302/0301-620X.98B1.36712. Review.


Systemic cobalt toxicity from total hip arthroplasties: review of a rare condition Part 1 - history, mechanism, measurements, and pathophysiology.

Cheung AC, Banerjee S, Cherian JJ, Wong F, Butany J, Gilbert C, Overgaard C, Syed K, Zywiel MG, Jacobs JJ, Mont MA.

Bone Joint J. 2016 Jan;98-B(1):6-13. doi: 10.1302/0301-620X.98B1.36374. Review.


Genome-Wide Annotation and Comparative Analysis of Cytochrome P450 Monooxygenases in Basidiomycete Biotrophic Plant Pathogens.

Qhanya LB, Matowane G, Chen W, Sun Y, Letsimo EM, Parvez M, Yu JH, Mashele SS, Syed K.

PLoS One. 2015 Nov 4;10(11):e0142100. doi: 10.1371/journal.pone.0142100. eCollection 2015.


Methylated Cytosines Mutate to Transcription Factor Binding Sites that Drive Tetrapod Evolution.

He X, Tillo D, Vierstra J, Syed KS, Deng C, Ray GJ, Stamatoyannopoulos J, FitzGerald PC, Vinson C.

Genome Biol Evol. 2015 Oct 27;7(11):3155-69. doi: 10.1093/gbe/evv205.


Novel clostridial fusants in comparison with co-cultured counterpart species for enhanced production of biobutanol using green renewable and sustainable feedstock.

Syed K, Dahman Y.

Bioprocess Biosyst Eng. 2015 Nov;38(11):2249-62. doi: 10.1007/s00449-015-1462-z. Epub 2015 Sep 22.


Cross-Sectional Contrast Between Individuals With Foot/Ankle vs Knee Osteoarthritis for Obesity and Low Education on Health-Related Quality of Life.

Perruccio AV, Gandhi R, Lau JT, Syed KA, Mahomed NN, Rampersaud YR.

Foot Ankle Int. 2016 Jan;37(1):24-32. doi: 10.1177/1071100715600282. Epub 2015 Sep 3.


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