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Items: 22


Neutralizing antibody-resistant hepatitis C virus cell-to-cell transmission.

Brimacombe CL, Grove J, Meredith LW, Hu K, Syder AJ, Flores MV, Timpe JM, Krieger SE, Baumert TF, Tellinghuisen TL, Wong-Staal F, Balfe P, McKeating JA.

J Virol. 2011 Jan;85(1):596-605. doi: 10.1128/JVI.01592-10. Epub 2010 Oct 20.


Small molecule scavenger receptor BI antagonists are potent HCV entry inhibitors.

Syder AJ, Lee H, Zeisel MB, Grove J, Soulier E, Macdonald J, Chow S, Chang J, Baumert TF, McKeating JA, McKelvy J, Wong-Staal F.

J Hepatol. 2011 Jan;54(1):48-55. doi: 10.1016/j.jhep.2010.06.024. Epub 2010 Aug 21.


Targeting HCV entry for development of therapeutics.

Wong-Staal F, Syder AJ, McKelvy JF.

Viruses. 2010 Aug;2(8):1718-33. doi: 10.3390/v2081718. Epub 2010 Aug 18.


Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures.

Ploss A, Khetani SR, Jones CT, Syder AJ, Trehan K, Gaysinskaya VA, Mu K, Ritola K, Rice CM, Bhatia SN.

Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3141-5. doi: 10.1073/pnas.0915130107. Epub 2010 Feb 1.


Real-time imaging of hepatitis C virus infection using a fluorescent cell-based reporter system.

Jones CT, Catanese MT, Law LM, Khetani SR, Syder AJ, Ploss A, Oh TS, Schoggins JW, MacDonald MR, Bhatia SN, Rice CM.

Nat Biotechnol. 2010 Feb;28(2):167-71. doi: 10.1038/nbt.1604. Epub 2010 Jan 31.


Temporal proteome and lipidome profiles reveal hepatitis C virus-associated reprogramming of hepatocellular metabolism and bioenergetics.

Diamond DL, Syder AJ, Jacobs JM, Sorensen CM, Walters KA, Proll SC, McDermott JE, Gritsenko MA, Zhang Q, Zhao R, Metz TO, Camp DG 2nd, Waters KM, Smith RD, Rice CM, Katze MG.

PLoS Pathog. 2010 Jan;6(1):e1000719. doi: 10.1371/journal.ppat.1000719. Epub 2010 Jan 8.


Genomic analysis reveals a potential role for cell cycle perturbation in HCV-mediated apoptosis of cultured hepatocytes.

Walters KA, Syder AJ, Lederer SL, Diamond DL, Paeper B, Rice CM, Katze MG.

PLoS Pathog. 2009 Jan;5(1):e1000269. doi: 10.1371/journal.ppat.1000269. Epub 2009 Jan 16.


Claudin-1 is a hepatitis C virus co-receptor required for a late step in entry.

Evans MJ, von Hahn T, Tscherne DM, Syder AJ, Panis M, Wölk B, Hatziioannou T, McKeating JA, Bieniasz PD, Rice CM.

Nature. 2007 Apr 12;446(7137):801-5. Epub 2007 Feb 25. Erratum in: Nature. 2007 Apr 12;446(7137):1 p following 805.


Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro.

Lindenbach BD, Meuleman P, Ploss A, Vanwolleghem T, Syder AJ, McKeating JA, Lanford RE, Feinstone SM, Major ME, Leroux-Roels G, Rice CM.

Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3805-9. Epub 2006 Feb 16.


Complete replication of hepatitis C virus in cell culture.

Lindenbach BD, Evans MJ, Syder AJ, Wölk B, Tellinghuisen TL, Liu CC, Maruyama T, Hynes RO, Burton DR, McKeating JA, Rice CM.

Science. 2005 Jul 22;309(5734):623-6. Epub 2005 Jun 9.


A transgenic mouse model of metastatic carcinoma involving transdifferentiation of a gastric epithelial lineage progenitor to a neuroendocrine phenotype.

Syder AJ, Karam SM, Mills JC, Ippolito JE, Ansari HR, Farook V, Gordon JI.

Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4471-6.


The impact of parietal cells on Helicobacter pylori tropism and host pathology: an analysis using gnotobiotic normal and transgenic mice.

Syder AJ, Oh JD, Guruge JL, O'Donnell D, Karlsson M, Mills JC, Björkholm BM, Gordon JI.

Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3467-72. Epub 2003 Mar 10.


Colonization of germ-free transgenic mice with genotyped Helicobacter pylori strains from a case-control study of gastric cancer reveals a correlation between host responses and HsdS components of type I restriction-modification systems.

Björkholm BM, Guruge JL, Oh JD, Syder AJ, Salama N, Guillemin K, Falkow S, Nilsson C, Falk PG, Engstrand L, Gordon JI.

J Biol Chem. 2002 Sep 13;277(37):34191-7. Epub 2002 Jul 8.


Genetic mosaic analysis indicates that the bulb region of coat hair follicles contains a resident population of several active multipotent epithelial lineage progenitors.

Kopan R, Lee J, Lin MH, Syder AJ, Kesterson J, Crutchfield N, Li CR, Wu W, Books J, Gordon JI.

Dev Biol. 2002 Feb 1;242(1):44-57.


Genetic mosaic analysis reveals that GATA-4 is required for proper differentiation of mouse gastric epithelium.

Jacobsen CM, Narita N, Bielinska M, Syder AJ, Gordon JI, Wilson DB.

Dev Biol. 2002 Jan 1;241(1):34-46.


A molecular profile of the mouse gastric parietal cell with and without exposure to Helicobacter pylori.

Mills JC, Syder AJ, Hong CV, Guruge JL, Raaii F, Gordon JI.

Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13687-92.


Theoretical and experimental approaches for studying factors defining the Helicobacter pylori-host relationship.

Falk PG, Syder AJ, Guruge JL, Kirschner D, Blaser MJ, Gordon JI.

Trends Microbiol. 2000 Jul;8(7):321-9. Review.


Helicobacter pylori attaches to NeuAc alpha 2,3Gal beta 1,4 glycoconjugates produced in the stomach of transgenic mice lacking parietal cells.

Syder AJ, Guruge JL, Li Q, Hu Y, Oleksiewicz CM, Lorenz RG, Karam SM, Falk PG, Gordon JI.

Mol Cell. 1999 Mar;3(3):263-74.


Genetic and clinical mosaicism in a type of epidermal nevus.

Paller AS, Syder AJ, Chan YM, Yu QC, Hutton E, Tadini G, Fuchs E.

N Engl J Med. 1994 Nov 24;331(21):1408-15.


The genetic basis of epidermolytic hyperkeratosis: a disorder of differentiation-specific epidermal keratin genes.

Cheng J, Syder AJ, Yu QC, Letai A, Paller AS, Fuchs E.

Cell. 1992 Sep 4;70(5):811-9.


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