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Items: 43

1.

Hepatobiliary Disposition of Atovaquone: A Case of Mechanistically Unusual Biliary Clearance.

Patel M, Johnson M, Sychterz CJ, Lewis GJ, Watson C, Ellens H, Polli JW, Zamek-Gliszczynski MJ.

J Pharmacol Exp Ther. 2018 Jul;366(1):37-45. doi: 10.1124/jpet.117.247254. Epub 2018 Apr 13.

PMID:
29653960
2.

Single ocular injection of a sustained-release anti-VEGF delivers 6months pharmacokinetics and efficacy in a primate laser CNV model.

Adamson P, Wilde T, Dobrzynski E, Sychterz C, Polsky R, Kurali E, Haworth R, Tang CM, Korczynska J, Cook F, Papanicolaou I, Tsikna L, Roberts C, Hughes-Thomas Z, Walford J, Gibson D, Warrack J, Smal J, Verrijk R, Miller PE, Nork TM, Prusakiewicz J, Streit T, Sorden S, Struble C, Christian B, Catchpole IR.

J Control Release. 2016 Dec 28;244(Pt A):1-13. doi: 10.1016/j.jconrel.2016.10.026. Epub 2016 Nov 1.

3.

Interrogating the relationship between rat in vivo tissue distribution and drug property data for >200 structurally unrelated molecules.

Harrell AW, Sychterz C, Ho MY, Weber A, Valko K, Negash K.

Pharmacol Res Perspect. 2015 Oct;3(5):e00173. doi: 10.1002/prp2.173. Epub 2015 Aug 10.

4.

Bioavailability, metabolism and disposition of oral pazopanib in patients with advanced cancer.

Deng Y, Sychterz C, Suttle AB, Dar MM, Bershas D, Negash K, Qian Y, Chen EP, Gorycki PD, Ho MY.

Xenobiotica. 2013 May;43(5):443-53. doi: 10.3109/00498254.2012.734642. Epub 2012 Nov 16.

PMID:
23548165
5.

Assessing a novel depot delivery strategy for noninvasive administration of VEGF/PDGF RTK inhibitors for ocular neovascular disease.

Robbie SJ, Lundh von Leithner P, Ju M, Lange CA, King AG, Adamson P, Lee D, Sychterz C, Coffey P, Ng YS, Bainbridge JW, Shima DT.

Invest Ophthalmol Vis Sci. 2013 Feb 27;54(2):1490-500. doi: 10.1167/iovs.12-10169.

PMID:
23385800
6.

Investigations of hydrazine cleavage of eltrombopag in humans.

Deng Y, Rogers M, Sychterz C, Talley K, Qian Y, Bershas D, Ho M, Shi W, Chen EP, Serabjit-Singh C, Gorycki PD.

Drug Metab Dispos. 2011 Sep;39(9):1747-54. doi: 10.1124/dmd.111.040188. Epub 2011 Jun 6.

PMID:
21646438
7.

Comparison of CT, MRI, and radiographs in assessing pelvic osteolysis: a cadaveric study.

Walde TA, Weiland DE, Leung SB, Kitamura N, Sychterz CJ, Engh CA Jr, Claus AM, Potter HG, Engh CA Sr.

Clin Orthop Relat Res. 2005 Aug;(437):138-44.

PMID:
16056041
8.

Magnetic resonance imaging in the evaluation of periprosthetic acetabular osteolysis: a cadaveric study.

Weiland DE, Walde TA, Leung SB, Sychterz CJ, Ho S, Engh CA, Potter HG.

J Orthop Res. 2005 Jul;23(4):713-9. Epub 2005 Apr 12.

9.

Conventional ultra-high molecular weight polyethylene: a gold standard of sorts.

Engh CA, Sychterz CJ, Engh CA Jr.

Instr Course Lect. 2005;54:183-7. Review.

PMID:
15948445
10.

The relationship between shelf life and in vivo wear for polyethylene acetabular liners.

Sychterz CJ, Young AM, Orishimo K, Engh CA.

J Arthroplasty. 2005 Feb;20(2):168-73.

PMID:
15902855
11.

Computed tomography to assess pelvic lysis after total hip replacement.

Claus AM, Totterman SM, Sychterz CJ, Tamez-Peña JG, Looney RJ, Engh CA Sr.

Clin Orthop Relat Res. 2004 May;(422):167-74.

PMID:
15187852
12.

Sterilization and polyethylene wear: clinical studies to support laboratory data.

Sychterz CJ, Orishimo KF, Engh CA.

J Bone Joint Surg Am. 2004 May;86(5):1017-22.

PMID:
15118047
13.

Radiographic definition of pelvic osteolysis following total hip arthroplasty.

Claus AM, Engh CA Jr, Sychterz CJ, Xenos JS, Orishimo KF, Engh CA Sr.

J Bone Joint Surg Am. 2003 Aug;85(8):1519-26.

PMID:
12925632
14.
15.

Can component and patient factors account for the variance in wear rates among bilateral total hip arthroplasty patients?

Orishimo KF, Sychterz CJ, Hopper RH Jr, Engh CA.

J Arthroplasty. 2003 Feb;18(2):154-60.

PMID:
12629604
16.

What we have learned about long-term cementless fixation from autopsy retrievals.

Sychterz CJ, Claus AM, Engh CA.

Clin Orthop Relat Res. 2002 Dec;(405):79-91.

PMID:
12461359
17.

Polyethylene liner exchange for excessive wear and osteolysis.

Terefenko KM, Sychterz CJ, Orishimo K, Engh CA Sr.

J Arthroplasty. 2002 Sep;17(6):798-804.

PMID:
12216039
18.

Interobserver and intraobserver variability in radiographic assessment of osteolysis.

Engh CA Jr, Sychterz CJ, Young AM, Pollock DC, Toomey SD, Engh CA Sr.

J Arthroplasty. 2002 Sep;17(6):752-9.

PMID:
12216030
19.

Standardized analysis of UHMWPE wear particles from failed total joint arthroplasties.

Mabrey JD, Afsar-Keshmiri A, Engh GA, Sychterz CJ, Wirth MA, Rockwood CA, Agrawal CM.

J Biomed Mater Res. 2002;63(5):475-83.

PMID:
12209890
20.

Effect of acetabular modularity on polyethylene wear and osteolysis in total hip arthroplasty.

Young AM, Sychterz CJ, Hopper RH Jr, Engh CA.

J Bone Joint Surg Am. 2002 Jan;84(1):58-63.

PMID:
11792780
21.

Pattern of osteolysis around two different cementless metal-backed cups: retrospective, radiographic analysis at minimum 10-year follow-up.

Claus AM, Sychterz CJ, Hopper RH Jr, Engh CA.

J Arthroplasty. 2001 Dec;16(8 Suppl 1):177-82.

PMID:
11742472
22.

A clinically practical method of manually assessing polyethylene liner thickness.

Pollock D, Sychterz CJ, Engh CA.

J Bone Joint Surg Am. 2001 Dec;83(12):1803-9.

PMID:
11741058
23.

Effect of femoral stiffness on bone remodeling after uncemented arthroplasty.

Sychterz CJ, Topoleski LD, Sacco M, Engh CA Sr.

Clin Orthop Relat Res. 2001 Aug;(389):218-27.

PMID:
11501814
24.

Effect of radiographic quality on computer-assisted head penetration measurements.

Sychterz CJ, Young AM, Engh CA.

Clin Orthop Relat Res. 2001 May;(386):150-8.

PMID:
11347828
25.

The accuracy and reproducibility of radiographic assessment of stress-shielding. A postmortem analysis.

Engh CA Jr, McAuley JP, Sychterz CJ, Sacco ME, Engh CA Sr.

J Bone Joint Surg Am. 2000 Oct;82(10):1414-20.

PMID:
11057469
26.

Comparison of in vivo wear between polyethylene liners articulating with ceramic and cobalt-chrome femoral heads.

Sychterz CJ, Engh CA Jr, Young AM, Hopper RH Jr, Engh CA.

J Bone Joint Surg Br. 2000 Sep;82(7):948-51.

PMID:
11041580
27.

Characterization of long-term femoral-head-penetration rates. Association with and prediction of osteolysis.

Dowd JE, Sychterz CJ, Young AM, Engh CA.

J Bone Joint Surg Am. 2000 Aug;82(8):1102-7.

PMID:
10954099
28.

Comparison of head penetration into Hylamer and Enduron polyethylene liners: a follow-up report.

Sychterz CJ, Young AM, McAuley JP, Engh CA.

J Arthroplasty. 2000 Apr;15(3):372-4. No abstract available.

PMID:
10794235
29.

Influence of porous coating level on proximal femoral remodeling. A postmortem analysis.

McAuley JP, Sychterz CJ, Engh CA Sr.

Clin Orthop Relat Res. 2000 Feb;(371):146-53.

PMID:
10693561
30.

Migration of polyethylene wear debris in one type of uncemented femoral component with circumferential porous coating: an autopsy study of 5 femurs.

von Knoch M, Engh CA Sr, Sychterz CJ, Engh CA Jr, Willert HG.

J Arthroplasty. 2000 Jan;15(1):72-8.

PMID:
10654466
31.

The effect of weight-bearing on the radiographic measurement of the position of the femoral head after total hip arthroplasty.

Moore KD, Barrack RL, Sychterz CJ, Sawhney J, Yang AM, Engh CA.

J Bone Joint Surg Am. 2000 Jan;82(1):62-9.

PMID:
10653085
32.

Two-dimensional versus three-dimensional radiographic measurements of polyethylene wear.

Sychterz CJ, Yang AM, McAuley JP, Engh CA.

Clin Orthop Relat Res. 1999 Aug;(365):117-23.

PMID:
10627695
33.

Factors affecting femoral bone remodeling after cementless total hip arthroplasty.

Engh CA Jr, Sychterz C, Engh C Sr.

J Arthroplasty. 1999 Aug;14(5):637-44.

PMID:
10475568
34.

Analysis of temporal wear patterns of porous-coated acetabular components: distinguishing between true wear and so-called bedding-in.

Sychterz CJ, Engh CA Jr, Yang A, Engh CA.

J Bone Joint Surg Am. 1999 Jun;81(6):821-30.

PMID:
10391547
35.

Analysis of prosthetic femoral heads retrieved at autopsy.

Sychterz CJ, Engh CA Jr, Swope SW, McNulty DE, Engh CA.

Clin Orthop Relat Res. 1999 Jan;(358):223-34.

PMID:
9973995
36.
37.

Incidence of late bead shedding from uncemented porous coated cups. A radiographic evaluation.

von Knoch M, Sychterz CJ, Engh CA Jr, Engh CA Sr.

Clin Orthop Relat Res. 1997 Sep;(342):99-105.

PMID:
9308531
38.

Radiographic evaluation of penetration by the femoral head into the polyethylene liner over time.

Sychterz CJ, Engh CA Jr, Shah N, Engh CA Sr.

J Bone Joint Surg Am. 1997 Jul;79(7):1040-6.

PMID:
9234880
39.

The Otto Aufranc Award. Skeletal response to well fixed femoral components inserted with and without cement.

Maloney WJ, Sychterz C, Bragdon C, McGovern T, Jasty M, Engh CA, Harris WH.

Clin Orthop Relat Res. 1996 Dec;(333):15-26.

PMID:
8981879
40.

Bone remodeling around cementless hip implants.

Bugbee WD, Sychterz CJ, Engh CA.

South Med J. 1996 Nov;89(11):1036-40.

PMID:
8903283
41.

An analysis of a retrieved Prodigy femoral prosthesis.

Moon KH, Vinh T, Sychterz CJ, Engh CA.

J Arthroplasty. 1996 Aug;11(5):629-36.

PMID:
8872588
42.

Wear of polyethylene cups in total hip arthroplasty. A study of specimens retrieved post mortem.

Sychterz CJ, Moon KH, Hashimoto Y, Terefenko KM, Engh CA Jr, Bauer TW.

J Bone Joint Surg Am. 1996 Aug;78(8):1193-200.

PMID:
8753711
43.

The influence of clinical factors on periprosthetic bone remodeling.

Sychterz CJ, Engh CA.

Clin Orthop Relat Res. 1996 Jan;(322):285-92.

PMID:
8542707

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