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Items: 1 to 50 of 163

1.

Imaging-assisted nanoimmunotherapy for atherosclerosis in multiple species.

Binderup T, Duivenvoorden R, Fay F, van Leent MMT, Malkus J, Baxter S, Ishino S, Zhao Y, Sanchez-Gaytan B, Teunissen AJP, Frederico YCA, Tang J, Carlucci G, Lyashchenko S, Calcagno C, Karakatsanis N, Soultanidis G, Senders ML, Robson PM, Mani V, Ramachandran S, Lobatto ME, Hutten BA, Granada JF, Reiner T, Swirski FK, Nahrendorf M, Kjaer A, Fisher EA, Fayad ZA, Pérez-Medina C, Mulder WJM.

Sci Transl Med. 2019 Aug 21;11(506). pii: eaaw7736. doi: 10.1126/scitranslmed.aaw7736.

PMID:
31434756
2.

Wnt5a-Mediated Neutrophil Recruitment Has an Obligatory Role in Pressure Overload-Induced Cardiac Dysfunction.

Wang Y, Sano S, Oshima K, Sano M, Watanabe Y, Katanasaka Y, Yura Y, Jung C, Anzai A, Swirski FK, Gokce N, Walsh K.

Circulation. 2019 Aug 6;140(6):487-499. doi: 10.1161/CIRCULATIONAHA.118.038820. Epub 2019 Jun 7.

PMID:
31170826
3.

Caveolin-1 Regulates Atherogenesis by Attenuating Low-Density Lipoprotein Transcytosis and Vascular Inflammation Independently of Endothelial Nitric Oxide Synthase Activation.

Ramírez CM, Zhang X, Bandyopadhyay C, Rotllan N, Sugiyama MG, Aryal B, Liu X, He S, Kraehling JR, Ulrich V, Lin CS, Velazquez H, Lasunción MA, Li G, Suárez Y, Tellides G, Swirski FK, Lee WL, Schwartz MA, Sessa WC, Fernández-Hernando C.

Circulation. 2019 Jul 16;140(3):225-239. doi: 10.1161/CIRCULATIONAHA.118.038571. Epub 2019 Jun 3.

PMID:
31154825
4.

c-Myb Exacerbates Atherosclerosis through Regulation of Protective IgM-Producing Antibody-Secreting Cells.

Shikatani EA, Besla R, Ensan S, Upadhye A, Khyzha N, Li A, Emoto T, Chiu F, Degousee N, Moreau JM, Perry HM, Thayaparan D, Cheng HS, Pacheco S, Smyth D, Noyan H, Zavitz CCJ, Bauer CMT, Hilgendorf I, Libby P, Swirski FK, Gommerman JL, Fish JE, Stampfli MR, Cybulsky MI, Rubin BB, Paige CJ, Bender TP, McNamara CA, Husain M, Robbins CS.

Cell Rep. 2019 May 21;27(8):2304-2312.e6. doi: 10.1016/j.celrep.2019.04.090.

5.

Growth Factors as Immunotherapeutic Targets in Cardiovascular Disease.

Mindur JE, Swirski FK.

Arterioscler Thromb Vasc Biol. 2019 Jul;39(7):1275-1287. doi: 10.1161/ATVBAHA.119.311994. Epub 2019 May 16.

PMID:
31092009
6.

Author Correction: Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates.

Lameijer M, Binderup T, van Leent MMT, Senders ML, Fay F, Malkus J, Sanchez-Gaytan BL, Teunissen AJP, Karakatsanis N, Robson P, Zhou X, Ye Y, Wojtkiewicz G, Tang J, Seijkens TTP, Kroon J, Stroes ESG, Kjaer A, Ochando J, Reiner T, Pérez-Medina C, Calcagno C, Fisher EA, Zhang B, Temel RE, Swirski FK, Nahrendorf M, Fayad ZA, Lutgens E, Mulder WJM, Duivenvoorden R.

Nat Biomed Eng. 2018 Aug;2(8):623. doi: 10.1038/s41551-018-0281-3.

PMID:
31015637
7.

Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates.

Lameijer M, Binderup T, van Leent MMT, Senders ML, Fay F, Malkus J, Sanchez-Gaytan BL, Teunissen AJP, Karakatsanis N, Robson P, Zhou X, Ye Y, Wojtkiewicz G, Tang J, Seijkens TTP, Kroon J, Stroes ESG, Kjaer A, Ochando J, Reiner T, Pérez-Medina C, Calcagno C, Fisher EA, Zhang B, Temel RE, Swirski FK, Nahrendorf M, Fayad ZA, Lutgens E, Mulder WJM, Duivenvoorden R.

Nat Biomed Eng. 2018 May;2(5):279-292. doi: 10.1038/s41551-018-0221-2. Epub 2018 Apr 16. Erratum in: Nat Biomed Eng. 2018 Aug;2(8):623.

8.

Glucocorticoids Regulate Bone Marrow B Lymphopoiesis After Stroke.

Courties G, Frodermann V, Honold L, Zheng Y, Herisson F, Schloss MJ, Sun Y, Presumey J, Severe N, Engblom C, Hulsmans M, Cremer S, Rohde D, Pittet MJ, Scadden DT, Swirski FK, Kim DE, Moskowitz MA, Nahrendorf M.

Circ Res. 2019 Apr 26;124(9):1372-1385. doi: 10.1161/CIRCRESAHA.118.314518.

PMID:
30782088
9.

Sleep modulates haematopoiesis and protects against atherosclerosis.

McAlpine CS, Kiss MG, Rattik S, He S, Vassalli A, Valet C, Anzai A, Chan CT, Mindur JE, Kahles F, Poller WC, Frodermann V, Fenn AM, Gregory AF, Halle L, Iwamoto Y, Hoyer FF, Binder CJ, Libby P, Tafti M, Scammell TE, Nahrendorf M, Swirski FK.

Nature. 2019 Feb;566(7744):383-387. doi: 10.1038/s41586-019-0948-2. Epub 2019 Feb 13.

10.

Gut intraepithelial T cells calibrate metabolism and accelerate cardiovascular disease.

He S, Kahles F, Rattik S, Nairz M, McAlpine CS, Anzai A, Selgrade D, Fenn AM, Chan CT, Mindur JE, Valet C, Poller WC, Halle L, Rotllan N, Iwamoto Y, Wojtkiewicz GR, Weissleder R, Libby P, Fernández-Hernando C, Drucker DJ, Nahrendorf M, Swirski FK.

Nature. 2019 Feb;566(7742):115-119. doi: 10.1038/s41586-018-0849-9. Epub 2019 Jan 30.

11.

Stage-dependent differential effects of interleukin-1 isoforms on experimental atherosclerosis.

Vromman A, Ruvkun V, Shvartz E, Wojtkiewicz G, Santos Masson G, Tesmenitsky Y, Folco E, Gram H, Nahrendorf M, Swirski FK, Sukhova GK, Libby P.

Eur Heart J. 2019 Aug 7;40(30):2482-2491. doi: 10.1093/eurheartj/ehz008.

PMID:
30698710
12.

Self-reactive CD4+ IL-3+ T cells amplify autoimmune inflammation in myocarditis by inciting monocyte chemotaxis.

Anzai A, Mindur JE, Halle L, Sano S, Choi JL, He S, McAlpine CS, Chan CT, Kahles F, Valet C, Fenn AM, Nairz M, Rattik S, Iwamoto Y, Fairweather D, Walsh K, Libby P, Nahrendorf M, Swirski FK.

J Exp Med. 2019 Feb 4;216(2):369-383. doi: 10.1084/jem.20180722. Epub 2019 Jan 22.

13.

A Miniaturized, Programmable Pacemaker for Long-Term Studies in the Mouse.

Hulsmans M, Aguirre AD, Bonner MD, Bapat A, Cremer S, Iwamoto Y, King KR, Swirski FK, Milan DJ, Weissleder R, Nahrendorf M.

Circ Res. 2018 Nov 9;123(11):1208-1219. doi: 10.1161/CIRCRESAHA.118.313429.

PMID:
30571465
14.

Reply to 'Cardioimmunology of arrhythmias: the role of autoimmune and inflammatory cardiac channelopathies'.

Swirski FK, Nahrendorf M.

Nat Rev Immunol. 2019 Jan;19(1):65. doi: 10.1038/s41577-018-0099-y. No abstract available.

PMID:
30552386
15.

Inhibiting Inflammation with Myeloid Cell-Specific Nanobiologics Promotes Organ Transplant Acceptance.

Braza MS, van Leent MMT, Lameijer M, Sanchez-Gaytan BL, Arts RJW, Pérez-Medina C, Conde P, Garcia MR, Gonzalez-Perez M, Brahmachary M, Fay F, Kluza E, Kossatz S, Dress RJ, Salem F, Rialdi A, Reiner T, Boros P, Strijkers GJ, Calcagno CC, Ginhoux F, Marazzi I, Lutgens E, Nicolaes GAF, Weber C, Swirski FK, Nahrendorf M, Fisher EA, Duivenvoorden R, Fayad ZA, Netea MG, Mulder WJM, Ochando J.

Immunity. 2018 Nov 20;49(5):819-828.e6. doi: 10.1016/j.immuni.2018.09.008. Epub 2018 Nov 6.

PMID:
30413362
16.

Monocyte and Macrophage Dynamics in the Cardiovascular System: JACC Macrophage in CVD Series (Part 3).

Fayad ZA, Swirski FK, Calcagno C, Robbins CS, Mulder W, Kovacic JC.

J Am Coll Cardiol. 2018 Oct 30;72(18):2198-2212. doi: 10.1016/j.jacc.2018.08.2150. Review.

PMID:
30360828
17.

Rings of Fire.

Swirski FK.

Arterioscler Thromb Vasc Biol. 2018 Aug;38(8):1671-1672. doi: 10.1161/ATVBAHA.118.311389. No abstract available.

PMID:
30354199
18.

Cardioimmunology: the immune system in cardiac homeostasis and disease.

Swirski FK, Nahrendorf M.

Nat Rev Immunol. 2018 Dec;18(12):733-744. doi: 10.1038/s41577-018-0065-8. Review.

PMID:
30228378
19.

Direct vascular channels connect skull bone marrow and the brain surface enabling myeloid cell migration.

Herisson F, Frodermann V, Courties G, Rohde D, Sun Y, Vandoorne K, Wojtkiewicz GR, Masson GS, Vinegoni C, Kim J, Kim DE, Weissleder R, Swirski FK, Moskowitz MA, Nahrendorf M.

Nat Neurosci. 2018 Sep;21(9):1209-1217. doi: 10.1038/s41593-018-0213-2. Epub 2018 Aug 27.

20.

A CRISPR Take on Clonal Hematopoiesis.

Swirski FK.

Circ Res. 2018 Jul 20;123(3):313-314. doi: 10.1161/CIRCRESAHA.118.313347. No abstract available.

PMID:
30026373
21.

Imaging the Vascular Bone Marrow Niche During Inflammatory Stress.

Vandoorne K, Rohde D, Kim HY, Courties G, Wojtkiewicz G, Honold L, Hoyer FF, Frodermann V, Nayar R, Herisson F, Jung Y, Désogère PA, Vinegoni C, Caravan P, Weissleder R, Sosnovik DE, Lin CP, Swirski FK, Nahrendorf M.

Circ Res. 2018 Aug 3;123(4):415-427. doi: 10.1161/CIRCRESAHA.118.313302.

22.

Multimodal Molecular Imaging Demonstrates Myeloperoxidase Regulation of Matrix Metalloproteinase Activity in Neuroinflammation.

Zhang Y, Dong H, Seeburg DP, Wojtkiewicz GR, Waterman P, Pulli B, Forghani R, Ali M, Iwamoto Y, Swirski FK, Chen JW.

Mol Neurobiol. 2019 Feb;56(2):954-962. doi: 10.1007/s12035-018-1137-2. Epub 2018 May 28.

PMID:
29808380
23.

Is defective cholesterol efflux an integral inflammatory component in myelopoiesis-driven cardiovascular diseases?

Yvan-Charvet L, Swirski FK.

Eur Heart J. 2018 Jun 14;39(23):2168-2171. doi: 10.1093/eurheartj/ehy269. No abstract available.

PMID:
29771312
24.

Integrated Biosensor for Rapid and Point-of-Care Sepsis Diagnosis.

Min J, Nothing M, Coble B, Zheng H, Park J, Im H, Weber GF, Castro CM, Swirski FK, Weissleder R, Lee H.

ACS Nano. 2018 Apr 24;12(4):3378-3384. doi: 10.1021/acsnano.7b08965. Epub 2018 Mar 20.

25.

Clonal Hematopoiesis Wages War on the Myocardium.

Swirski FK, Nahrendorf M.

J Am Coll Cardiol. 2018 Feb 27;71(8):887-889. doi: 10.1016/j.jacc.2017.12.038. No abstract available.

26.

Cardiac macrophages promote diastolic dysfunction.

Hulsmans M, Sager HB, Roh JD, Valero-Muñoz M, Houstis NE, Iwamoto Y, Sun Y, Wilson RM, Wojtkiewicz G, Tricot B, Osborne MT, Hung J, Vinegoni C, Naxerova K, Sosnovik DE, Zile MR, Bradshaw AD, Liao R, Tawakol A, Weissleder R, Rosenzweig A, Swirski FK, Sam F, Nahrendorf M.

J Exp Med. 2018 Feb 5;215(2):423-440. doi: 10.1084/jem.20171274. Epub 2018 Jan 16.

27.

Inflammation and CVD in 2017: From clonal haematopoiesis to the CANTOS trial.

Swirski FK.

Nat Rev Cardiol. 2018 Feb;15(2):79-80. doi: 10.1038/nrcardio.2017.208. Epub 2017 Dec 21. No abstract available.

PMID:
29263444
28.

Cibinetide dampens innate immune cell functions thus ameliorating the course of experimental colitis.

Nairz M, Haschka D, Dichtl S, Sonnweber T, Schroll A, Aßhoff M, Mindur JE, Moser PL, Wolf D, Swirski FK, Theurl I, Cerami A, Brines M, Weiss G.

Sci Rep. 2017 Oct 12;7(1):13012. doi: 10.1038/s41598-017-13046-3.

29.

The infarcted myocardium solicits GM-CSF for the detrimental oversupply of inflammatory leukocytes.

Anzai A, Choi JL, He S, Fenn AM, Nairz M, Rattik S, McAlpine CS, Mindur JE, Chan CT, Iwamoto Y, Tricot B, Wojtkiewicz GR, Weissleder R, Libby P, Nahrendorf M, Stone JR, Becher B, Swirski FK.

J Exp Med. 2017 Nov 6;214(11):3293-3310. doi: 10.1084/jem.20170689. Epub 2017 Oct 4.

30.

Unraveling Vascular Inflammation: From Immunology to Imaging.

Teague HL, Ahlman MA, Alavi A, Wagner DD, Lichtman AH, Nahrendorf M, Swirski FK, Nestle F, Gelfand JM, Kaplan MJ, Grinspoon S, Ridker PM, Newby DE, Tawakol A, Fayad ZA, Mehta NN.

J Am Coll Cardiol. 2017 Sep 12;70(11):1403-1412. doi: 10.1016/j.jacc.2017.07.750. Review.

31.

Cytokine storm and sepsis disease pathogenesis.

Chousterman BG, Swirski FK, Weber GF.

Semin Immunopathol. 2017 Jul;39(5):517-528. doi: 10.1007/s00281-017-0639-8. Epub 2017 May 29. Review.

PMID:
28555385
32.

Macrophages Facilitate Electrical Conduction in the Heart.

Hulsmans M, Clauss S, Xiao L, Aguirre AD, King KR, Hanley A, Hucker WJ, Wülfers EM, Seemann G, Courties G, Iwamoto Y, Sun Y, Savol AJ, Sager HB, Lavine KJ, Fishbein GA, Capen DE, Da Silva N, Miquerol L, Wakimoto H, Seidman CE, Seidman JG, Sadreyev RI, Naxerova K, Mitchell RN, Brown D, Libby P, Weissleder R, Swirski FK, Kohl P, Vinegoni C, Milan DJ, Ellinor PT, Nahrendorf M.

Cell. 2017 Apr 20;169(3):510-522.e20. doi: 10.1016/j.cell.2017.03.050.

33.

Flow Perturbation Mediates Neutrophil Recruitment and Potentiates Endothelial Injury via TLR2 in Mice: Implications for Superficial Erosion.

Franck G, Mawson T, Sausen G, Salinas M, Masson GS, Cole A, Beltrami-Moreira M, Chatzizisis Y, Quillard T, Tesmenitsky Y, Shvartz E, Sukhova GK, Swirski FK, Nahrendorf M, Aikawa E, Croce KJ, Libby P.

Circ Res. 2017 Jun 23;121(1):31-42. doi: 10.1161/CIRCRESAHA.117.310694. Epub 2017 Apr 20.

34.

Cholesterol, CCR2, and monocyte phenotypes in atherosclerosis.

Nahrendorf M, Swirski FK.

Eur Heart J. 2017 May 21;38(20):1594-1596. doi: 10.1093/eurheartj/ehx098. No abstract available.

PMID:
28329093
35.

"Pumping iron"-how macrophages handle iron at the systemic, microenvironmental, and cellular levels.

Nairz M, Theurl I, Swirski FK, Weiss G.

Pflugers Arch. 2017 Apr;469(3-4):397-418. doi: 10.1007/s00424-017-1944-8. Epub 2017 Mar 1. Review.

36.

Inflammation: Old, caffeinated, and healthy.

Swirski FK, Nahrendorf M.

Nat Rev Cardiol. 2017 Apr;14(4):194-196. doi: 10.1038/nrcardio.2017.22. Epub 2017 Mar 2. No abstract available.

PMID:
28250451
37.

Monocytosis, Hypercholesterolemia, and the Kinase That Binds Them.

Fenn AM, Swirski FK.

Arterioscler Thromb Vasc Biol. 2017 Feb;37(2):173-175. doi: 10.1161/ATVBAHA.116.308768. No abstract available.

PMID:
28122772
38.

Myeloperoxidase Nuclear Imaging for Epileptogenesis.

Zhang Y, Seeburg DP, Pulli B, Wojtkiewicz GR, Bure L, Atkinson W, Schob S, Iwamoto Y, Ali M, Zhang W, Rodriguez E, Milewski A, Keliher EJ, Wang C, Pan Y, Swirski FK, Chen JW.

Radiology. 2017 Feb;282(2):614. doi: 10.1148/radiol.2017164044. No abstract available.

PMID:
28099101
39.

Polyglucose nanoparticles with renal elimination and macrophage avidity facilitate PET imaging in ischaemic heart disease.

Keliher EJ, Ye YX, Wojtkiewicz GR, Aguirre AD, Tricot B, Senders ML, Groenen H, Fay F, Perez-Medina C, Calcagno C, Carlucci G, Reiner T, Sun Y, Courties G, Iwamoto Y, Kim HY, Wang C, Chen JW, Swirski FK, Wey HY, Hooker J, Fayad ZA, Mulder WJ, Weissleder R, Nahrendorf M.

Nat Commun. 2017 Jan 16;8:14064. doi: 10.1038/ncomms14064.

40.

Myeloperoxidase Inhibition Improves Ventricular Function and Remodeling After Experimental Myocardial Infarction.

Ali M, Pulli B, Courties G, Tricot B, Sebas M, Iwamoto Y, Hilgendorf I, Schob S, Dong A, Zheng W, Skoura A, Kalgukar A, Cortes C, Ruggeri R, Swirski FK, Nahrendorf M, Buckbinder L, Chen JW.

JACC Basic Transl Sci. 2016 Dec 26;1(7):633-643. doi: 10.1016/j.jacbts.2016.09.004. eCollection 2016 Dec. Review.

41.

Endothelial cells produce bone morphogenetic protein 6 required for iron homeostasis in mice.

Canali S, Zumbrennen-Bullough KB, Core AB, Wang CY, Nairz M, Bouley R, Swirski FK, Babitt JL.

Blood. 2017 Jan 26;129(4):405-414. doi: 10.1182/blood-2016-06-721571. Epub 2016 Nov 18.

42.

Immune cell screening of a nanoparticle library improves atherosclerosis therapy.

Tang J, Baxter S, Menon A, Alaarg A, Sanchez-Gaytan BL, Fay F, Zhao Y, Ouimet M, Braza MS, Longo VA, Abdel-Atti D, Duivenvoorden R, Calcagno C, Storm G, Tsimikas S, Moore KJ, Swirski FK, Nahrendorf M, Fisher EA, Pérez-Medina C, Fayad ZA, Reiner T, Mulder WJ.

Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):E6731-E6740. Epub 2016 Oct 17.

43.

Mechanisms of Myeloid Cell Modulation of Atherosclerosis.

Swirski FK, Nahrendorf M, Libby P.

Microbiol Spectr. 2016 Aug;4(4). doi: 10.1128/microbiolspec.MCHD-0026-2015. Review.

PMID:
27726819
44.

Bone Marrow Takes Center Stage in Cardiovascular Disease.

Swirski FK, Nahrendorf M.

Circ Res. 2016 Sep 2;119(6):701-3. doi: 10.1161/CIRCRESAHA.116.309584. No abstract available.

45.

E-Selectin Inhibition Mitigates Splenic HSC Activation and Myelopoiesis in Hypercholesterolemic Mice With Myocardial Infarction.

Dutta P, Hoyer FF, Sun Y, Iwamoto Y, Tricot B, Weissleder R, Magnani JL, Swirski FK, Nahrendorf M.

Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1802-8. doi: 10.1161/ATVBAHA.116.307519. Epub 2016 Jul 28.

46.

ANGPTL4 deficiency in haematopoietic cells promotes monocyte expansion and atherosclerosis progression.

Aryal B, Rotllan N, Araldi E, Ramírez CM, He S, Chousterman BG, Fenn AM, Wanschel A, Madrigal-Matute J, Warrier N, Martín-Ventura JL, Swirski FK, Suárez Y, Fernández-Hernando C.

Nat Commun. 2016 Jul 27;7:12313. doi: 10.1038/ncomms12313.

47.

Abandoning M1/M2 for a Network Model of Macrophage Function.

Nahrendorf M, Swirski FK.

Circ Res. 2016 Jul 22;119(3):414-7. doi: 10.1161/CIRCRESAHA.116.309194. Review. No abstract available.

48.

Proliferation and Recruitment Contribute to Myocardial Macrophage Expansion in Chronic Heart Failure.

Sager HB, Hulsmans M, Lavine KJ, Moreira MB, Heidt T, Courties G, Sun Y, Iwamoto Y, Tricot B, Khan OF, Dahlman JE, Borodovsky A, Fitzgerald K, Anderson DG, Weissleder R, Libby P, Swirski FK, Nahrendorf M.

Circ Res. 2016 Sep 16;119(7):853-64. doi: 10.1161/CIRCRESAHA.116.309001. Epub 2016 Jul 21.

49.

Reply: The Networks Between the Sympathetic Nervous System and Immune System in Atherosclerosis.

Libby P, Nahrendorf M, Swirski FK.

J Am Coll Cardiol. 2016 Jul 26;68(4):432. doi: 10.1016/j.jacc.2016.05.017. No abstract available.

50.

On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver.

Theurl I, Hilgendorf I, Nairz M, Tymoszuk P, Haschka D, Asshoff M, He S, Gerhardt LM, Holderried TA, Seifert M, Sopper S, Fenn AM, Anzai A, Rattik S, McAlpine C, Theurl M, Wieghofer P, Iwamoto Y, Weber GF, Harder NK, Chousterman BG, Arvedson TL, McKee M, Wang F, Lutz OM, Rezoagli E, Babitt JL, Berra L, Prinz M, Nahrendorf M, Weiss G, Weissleder R, Lin HY, Swirski FK.

Nat Med. 2016 Aug;22(8):945-51. doi: 10.1038/nm.4146. Epub 2016 Jul 18.

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