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Items: 1 to 50 of 56

1.

Author Correction: Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening.

Machutta CA, Kollmann CS, Lind KE, Bai X, Chan PF, Huang J, Ballell L, Belyanskaya S, Besra GS, Barros-Aguirre D, Bates RH, Centrella PA, Chang SS, Chai J, Choudhry AE, Coffin A, Davie CP, Deng H, Deng J, Ding Y, Dodson JW, Fosbenner DT, Gao EN, Graham TL, Graybill TL, Ingraham K, Johnson WP, King BW, Kwiatkowski CR, Lelièvre J, Li Y, Liu X, Lu Q, Lehr R, Mendoza-Losana A, Martin J, McCloskey L, McCormick P, O'Keefe HP, O'Keeffe T, Pao C, Phelps CB, Qi H, Rafferty K, Scavello GS, Steiginga MS, Sundersingh FS, Sweitzer SM, Szewczuk LM, Taylor A, Fern Toh M, Wang J, Wang M, Wilkins DJ, Xia B, Yao G, Zhang J, Zhou J, Donahue CP, Messer JA, Holmes D, Arico-Muendel CC, Pope AJ, Gross JW, Evindar G.

Nat Commun. 2018 Jul 13;9:16227. doi: 10.1038/ncomms16227.

2.

A High-Throughput Dose-Response Cellular Thermal Shift Assay for Rapid Screening of Drug Target Engagement in Living Cells, Exemplified Using SMYD3 and IDO1.

McNulty DE, Bonnette WG, Qi H, Wang L, Ho TF, Waszkiewicz A, Kallal LA, Nagarajan RP, Stern M, Quinn AM, Creasy CL, Su DS, Graves AP, Annan RS, Sweitzer SM, Holbert MA.

SLAS Discov. 2018 Jan;23(1):34-46. doi: 10.1177/2472555217732014. Epub 2017 Sep 28.

PMID:
28957646
3.

Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening.

Machutta CA, Kollmann CS, Lind KE, Bai X, Chan PF, Huang J, Ballell L, Belyanskaya S, Besra GS, Barros-Aguirre D, Bates RH, Centrella PA, Chang SS, Chai J, Choudhry AE, Coffin A, Davie CP, Deng H, Deng J, Ding Y, Dodson JW, Fosbenner DT, Gao EN, Graham TL, Graybill TL, Ingraham K, Johnson WP, King BW, Kwiatkowski CR, Lelièvre J, Li Y, Liu X, Lu Q, Lehr R, Mendoza-Losana A, Martin J, McCloskey L, McCormick P, O'Keefe HP, O'Keeffe T, Pao C, Phelps CB, Qi H, Rafferty K, Scavello GS, Steiginga MS, Sundersingh FS, Sweitzer SM, Szewczuk LM, Taylor A, Toh MF, Wang J, Wang M, Wilkins DJ, Xia B, Yao G, Zhang J, Zhou J, Donahue CP, Messer JA, Holmes D, Arico-Muendel CC, Pope AJ, Gross JW, Evindar G.

Nat Commun. 2017 Jul 17;8:16081. doi: 10.1038/ncomms16081. Erratum in: Nat Commun. 2018 Jul 13;9:16227.

4.

Crystallographic structure of a small molecule SIRT1 activator-enzyme complex.

Dai H, Case AW, Riera TV, Considine T, Lee JE, Hamuro Y, Zhao H, Jiang Y, Sweitzer SM, Pietrak B, Schwartz B, Blum CA, Disch JS, Caldwell R, Szczepankiewicz B, Oalmann C, Yee Ng P, White BH, Casaubon R, Narayan R, Koppetsch K, Bourbonais F, Wu B, Wang J, Qian D, Jiang F, Mao C, Wang M, Hu E, Wu JC, Perni RB, Vlasuk GP, Ellis JL.

Nat Commun. 2015 Jul 2;6:7645. doi: 10.1038/ncomms8645.

5.

Injury-specific promoters enhance herpes simplex virus-mediated gene therapy for treating neuropathic pain in rodents.

Smith SN, Paige C, Velazquez KT, Smith TP, Raja SN, Wilson SP, Sweitzer SM.

J Pain. 2015 Mar;16(3):283-90. doi: 10.1016/j.jpain.2014.12.007. Epub 2015 Jan 7.

6.

Modulation of pain in pediatric sickle cell disease: understanding the balance between endothelin mediated vasoconstriction and apelin mediated vasodilation.

Smith TP, Schlenz AM, Schatz JC, Maitra R, Sweitzer SM.

Blood Cells Mol Dis. 2015 Feb;54(2):155-9. doi: 10.1016/j.bcmd.2014.11.016. Epub 2014 Nov 26.

7.

Compounded pain formulations: what is the evidence?

Asbill S, Sweitzer SM, Spigener S, Romero-Sandoval A.

Int J Pharm Compd. 2014 Jul-Aug;18(4):278-86. Review.

PMID:
25474856
8.

Endothelin-1 induced desensitization in primary afferent neurons.

Smith TP, Smith SN, Sweitzer SM.

Neurosci Lett. 2014 Oct 17;582:59-64. doi: 10.1016/j.neulet.2014.09.002. Epub 2014 Sep 8.

9.

Evidence for the endothelin system as an emerging therapeutic target for the treatment of chronic pain.

Smith TP, Haymond T, Smith SN, Sweitzer SM.

J Pain Res. 2014 Aug 30;7:531-45. doi: 10.2147/JPR.S65923. eCollection 2014. Review.

10.

Endothelin-1-induced priming to capsaicin in young animals.

Smith T, Beasley S, Smith S, Mark I, Sweitzer SM.

Neurosci Lett. 2014 May 1;567:15-8. doi: 10.1016/j.neulet.2014.03.017. Epub 2014 Mar 24.

11.

Information-seeking coping behaviors during painful procedures in African-American children with sickle cell disease.

Schlenz AM, Schatz J, McClellan CB, Sweitzer SM, Roberts CW.

Pain Manag Nurs. 2013 Sep;14(3):e54-8. doi: 10.1016/j.pmn.2011.04.001. Epub 2011 Nov 4.

12.

Tolerance develops to the antiallodynic effects of the peripherally acting opioid loperamide hydrochloride in nerve-injured rats.

He SQ, Yang F, Perez FM, Xu Q, Shechter R, Cheong YK, Carteret AF, Dong X, Sweitzer SM, Raja SN, Guan Y.

Pain. 2013 Nov;154(11):2477-86. doi: 10.1016/j.pain.2013.07.023. Epub 2013 Jul 20.

13.

Evidence for a common mechanism of SIRT1 regulation by allosteric activators.

Hubbard BP, Gomes AP, Dai H, Li J, Case AW, Considine T, Riera TV, Lee JE, E SY, Lamming DW, Pentelute BL, Schuman ER, Stevens LA, Ling AJ, Armour SM, Michan S, Zhao H, Jiang Y, Sweitzer SM, Blum CA, Disch JS, Ng PY, Howitz KT, Rolo AP, Hamuro Y, Moss J, Perni RB, Ellis JL, Vlasuk GP, Sinclair DA.

Science. 2013 Mar 8;339(6124):1216-9. doi: 10.1126/science.1231097.

14.

Structures of human DPP7 reveal the molecular basis of specific inhibition and the architectural diversity of proline-specific peptidases.

Bezerra GA, Dobrovetsky E, Dong A, Seitova A, Crombett L, Shewchuk LM, Hassell AM, Sweitzer SM, Sweitzer TD, McDevitt PJ, Johanson KO, Kennedy-Wilson KM, Cossar D, Bochkarev A, Gruber K, Dhe-Paganon S.

PLoS One. 2012;7(8):e43019. doi: 10.1371/journal.pone.0043019. Epub 2012 Aug 29.

15.

Sensitization to acute procedural pain in pediatric sickle cell disease: modulation by painful vaso-occlusive episodes, age, and endothelin-1.

Schlenz AM, McClellan CB, Mark TR, McKelvy AD, Puffer E, Roberts CW, Sweitzer SM, Schatz JC.

J Pain. 2012 Jul;13(7):656-65. doi: 10.1016/j.jpain.2012.04.001. Epub 2012 May 24.

16.

Methyltransferases prefer monomer over core-trimmed nucleosomes as in vitro substrates.

Jiang Y, Schneck JL, Grimes M, Taylor AN, Hou W, Thrall SH, Sweitzer SM.

Anal Biochem. 2011 Aug 1;415(1):84-6. doi: 10.1016/j.ab.2011.03.037. Epub 2011 Apr 1.

PMID:
21459076
17.

Incorporating Scientific Publishing into an Undergraduate Neuroscience Course: A Case Study Using IMPULSE.

Jones LS, Allen L, Cronise K, Juneja N, Kohn R, McClellan K, Miller A, Nazir A, Patel A, Sweitzer SM, Vickery E, Walton A, Young R.

J Undergrad Neurosci Educ. 2011 Spring;9(2):A84-91. Epub 2011 Mar 15.

18.

Dynamic temporal and spatial regulation of mu opioid receptor expression in primary afferent neurons following spinal nerve injury.

Lee CY, Perez FM, Wang W, Guan X, Zhao X, Fisher JL, Guan Y, Sweitzer SM, Raja SN, Tao YX.

Eur J Pain. 2011 Aug;15(7):669-75. doi: 10.1016/j.ejpain.2010.11.018. Epub 2011 Feb 9.

19.

Metabotropic glutamate receptor-5 and protein kinase C-epsilon increase in dorsal root ganglion neurons and spinal glial activation in an adolescent rat model of painful neck injury.

Weisshaar CL, Dong L, Bowman AS, Perez FM, Guarino BB, Sweitzer SM, Winkelstein BA.

J Neurotrauma. 2010 Dec;27(12):2261-71. doi: 10.1089/neu.2010.1460.

PMID:
20925479
20.

Decreased opioid analgesia in weanling rats exposed to endothelin-1 during infancy.

McKelvy AD, Sweitzer SM.

Neurosci Lett. 2009 Dec 11;466(3):144-8. doi: 10.1016/j.neulet.2009.09.045. Epub 2009 Sep 27.

21.

Criterion and convergent validity for 4 measures of pain in a pediatric sickle cell disease population.

McClellan CB, Schatz JC, Mark TR, McKelvy A, Puffer E, Roberts CW, Sweitzer SM.

Clin J Pain. 2009 Feb;25(2):146-52. doi: 10.1097/AJP.0b013e3181839ac4.

22.

Endothelin-1 exposure on postnatal day 7 alters expression of the endothelin B receptor and behavioral sensitivity to endothelin-1 on postnatal day 11.

McKelvy AD, Sweitzer SM.

Neurosci Lett. 2009 Feb 13;451(1):89-93. doi: 10.1016/j.neulet.2008.12.027. Epub 2008 Dec 24.

23.

Rapid expression of recombinant proteins in modified CHO cells using the baculovirus system.

Ramos L, Kopec LA, Sweitzer SM, Fornwald JA, Zhao H, McAllister P, McNulty DE, Trill JJ, Kane JF.

Cytotechnology. 2002 Jan;38(1-3):37-41. doi: 10.1023/A:1021189628274.

24.

Neonatal morphine enhances nociception and decreases analgesia in young rats.

Zhang GH, Sweitzer SM.

Brain Res. 2008 Mar 14;1199:82-90. doi: 10.1016/j.brainres.2007.12.043. Epub 2008 Jan 3.

PMID:
18267316
25.

Enhanced peripheral analgesia using virally mediated gene transfer of the mu-opioid receptor in mice.

Zhang G, Mohammad H, Peper BD, Raja S, Wilson SP, Sweitzer SM.

Anesthesiology. 2008 Feb;108(2):305-13. doi: 10.1097/01.anes.0000299836.61785.79.

PMID:
18212576
26.

Age- and sex-specific nociceptive response to endothelin-1.

McKelvy AD, Mark TR, Sweitzer SM.

J Pain. 2007 Aug;8(8):657-66. Epub 2007 Jun 5.

PMID:
17553749
27.

Protein kinase C in pain: involvement of multiple isoforms.

Velázquez KT, Mohammad H, Sweitzer SM.

Pharmacol Res. 2007 Jun;55(6):578-89. Epub 2007 Apr 29. Review.

28.

Efficient expression of secreted proteases via recombinant BacMam virus.

Scott MJ, Modha SS, Rhodes AD, Broadway NM, Hardwicke PI, Zhao HJ, Kennedy-Wilson KM, Sweitzer SM, Martin SL.

Protein Expr Purif. 2007 Mar;52(1):104-16. Epub 2006 Oct 26.

PMID:
17129735
29.

Tolerance, opioid-induced allodynia and withdrawal associated allodynia in infant and young rats.

Zissen MH, Zhang G, McKelvy A, Propst JT, Kendig JJ, Sweitzer SM.

Neuroscience. 2007 Jan 5;144(1):247-62. Epub 2006 Oct 19.

30.

What is the future of diabetic wound care?

Sweitzer SM, Fann SA, Borg TK, Baynes JW, Yost MJ.

Diabetes Educ. 2006 Mar-Apr;32(2):197-210. Review.

PMID:
16554422
31.

Propentofylline attenuates vincristine-induced peripheral neuropathy in the rat.

Sweitzer SM, Pahl JL, DeLeo JA.

Neurosci Lett. 2006 Jun 12;400(3):258-61. Epub 2006 Mar 13.

PMID:
16530953
32.

Acute and chronic morphine alters formalin pain in neonatal rats.

Zissen MH, Zhang G, Kendig JJ, Sweitzer SM.

Neurosci Lett. 2006 May 29;400(1-2):154-7. Epub 2006 Mar 6.

PMID:
16517072
33.

Ethanol withdrawal-associated allodynia and hyperalgesia: age-dependent regulation by protein kinase C epsilon and gamma isoenzymes.

Shumilla JA, Liron T, Mochly-Rosen D, Kendig JJ, Sweitzer SM.

J Pain. 2005 Aug;6(8):535-49.

PMID:
16084468
34.

GABAB receptors on central terminals of C-afferents mediate intersegmental Adelta-afferent evoked hypoalgesia.

Jones TL, Sweitzer SM, Peters MC, Wilson SP, Yeomans DC.

Eur J Pain. 2005 Jun;9(3):233-42.

PMID:
15862472
35.

Hyperresponsiveness on washout of volatile anesthetics from isolated spinal cord compared to withdrawal from ethanol.

Wong SM, Sweitzer SM, Peters MC, Kendig JJ.

Anesth Analg. 2005 Feb;100(2):413-36.

PMID:
15673868
36.

Peripheral and central p38 MAPK mediates capsaicin-induced hyperalgesia.

Sweitzer SM, Peters MC, Ma JY, Kerr I, Mangadu R, Chakravarty S, Dugar S, Medicherla S, Protter AA, Yeomans DC.

Pain. 2004 Oct;111(3):278-85.

PMID:
15363871
37.

Ameroid rings for gradual chronic constriction of the sciatic nerve in rats: contribution of different nerves to neuropathic pain.

Tzabazis A, Kim PH, Sweitzer SM, Yeomans DC.

Brain Res Bull. 2004 Aug 30;64(2):127-32.

PMID:
15342099
38.

Acute and chronic ethanol exacerbates formalin pain in neonatal rats.

Shumilla JA, Sweitzer SM, Kendig JJ.

Neurosci Lett. 2004 Aug 26;367(1):29-33.

PMID:
15308291
39.

Acute and chronic ethanol does not affect incisional pain in neonatal rats.

Shumilla JA, Sweitzer SM, Kendig JJ.

Neurosci Lett. 2004 Aug 19;366(3):332-5.

PMID:
15288445
40.

Inhibition of spinal protein kinase C-epsilon or -gamma isozymes does not affect halothane minimum alveolar anesthetic concentration in rats.

Shumilla JA, Sweitzer SM, Eger EI 2nd, Laster MJ, Kendig JJ.

Anesth Analg. 2004 Jul;99(1):82-4.

PMID:
15281508
41.

Exaggerated nociceptive responses on morphine withdrawal: roles of protein kinase C epsilon and gamma.

Sweitzer SM, Wong SM, Tjolsen A, Allen CP, Mochly-Rosen D, Kendig JJ.

Pain. 2004 Jul;110(1-2):281-9.

PMID:
15275778
42.

Mechanical allodynia and thermal hyperalgesia upon acute opioid withdrawal in the neonatal rat.

Sweitzer SM, Allen CP, Zissen MH, Kendig JJ.

Pain. 2004 Jul;110(1-2):269-80.

PMID:
15275777
43.

Antinociceptive action of a p38alpha MAPK inhibitor, SD-282, in a diabetic neuropathy model.

Sweitzer SM, Medicherla S, Almirez R, Dugar S, Chakravarty S, Shumilla JA, Yeomans DC, Protter AA.

Pain. 2004 Jun;109(3):409-19.

PMID:
15157702
44.

Protein kinase C epsilon and gamma: involvement in formalin-induced nociception in neonatal rats.

Sweitzer SM, Wong SM, Peters MC, Mochly-Rosen D, Yeomans DC, Kendig JJ.

J Pharmacol Exp Ther. 2004 May;309(2):616-25. Epub 2004 Feb 4.

PMID:
14762097
45.

Differential opioid inhibition of C- and A delta- fiber mediated thermonociception after stimulation of the nucleus raphe magnus.

Lu Y, Sweitzer SM, Laurito CE, Yeomans DC.

Anesth Analg. 2004 Feb;98(2):414-9, table of contents.

PMID:
14742380
46.

Afferent fiber-selective shift in opiate potency following targeted opioid receptor knockdown.

Jones TL, Sweitzer SM, Wilson SP, Yeomans DC.

Pain. 2003 Dec;106(3):365-71.

PMID:
14659519
48.

Focal peripheral nerve injury induces leukocyte trafficking into the central nervous system: potential relationship to neuropathic pain.

Sweitzer SM, Hickey WF, Rutkowski MD, Pahl JL, DeLeo JA.

Pain. 2002 Nov;100(1-2):163-70.

PMID:
12435469
49.
50.

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