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Items: 1 to 50 of 85

1.

The intertwined metabolism during symbiotic nitrogen fixation elucidated by metabolic modelling.

Pfau T, Christian N, Masakapalli SK, Sweetlove LJ, Poolman MG, Ebenhöh O.

Sci Rep. 2018 Aug 21;8(1):12504. doi: 10.1038/s41598-018-30884-x.

2.

The role of dynamic enzyme assemblies and substrate channelling in metabolic regulation.

Sweetlove LJ, Fernie AR.

Nat Commun. 2018 May 30;9(1):2136. doi: 10.1038/s41467-018-04543-8. Review.

3.

Computational analysis of the productivity potential of CAM.

Shameer S, Baghalian K, Cheung CYM, Ratcliffe RG, Sweetlove LJ.

Nat Plants. 2018 Mar;4(3):165-171. doi: 10.1038/s41477-018-0112-2. Epub 2018 Feb 26.

PMID:
29483685
4.

Investigating the Role of the Photorespiratory Pathway in Non-photosynthetic Tissues.

Fernie AR, Bauwe H, Sweetlove LJ.

Methods Mol Biol. 2017;1653:217-225. doi: 10.1007/978-1-4939-7225-8_15.

PMID:
28822136
5.

Protein-protein interactions and metabolite channelling in the plant tricarboxylic acid cycle.

Zhang Y, Beard KFM, Swart C, Bergmann S, Krahnert I, Nikoloski Z, Graf A, Ratcliffe RG, Sweetlove LJ, Fernie AR, Obata T.

Nat Commun. 2017 May 16;8:15212. doi: 10.1038/ncomms15212.

6.

Microcompartmentation of cytosolic aldolase by interaction with the actin cytoskeleton in Arabidopsis.

Garagounis C, Kostaki KI, Hawkins TJ, Cummins I, Fricker MD, Hussey PJ, Hetherington AM, Sweetlove LJ.

J Exp Bot. 2017 Feb 1;68(5):885-898. doi: 10.1093/jxb/erx015.

PMID:
28338736
7.

Engineering central metabolism - a grand challenge for plant biologists.

Sweetlove LJ, Nielsen J, Fernie AR.

Plant J. 2017 May;90(4):749-763. doi: 10.1111/tpj.13464. Epub 2017 Mar 11.

8.

MSL1 is a mechanosensitive ion channel that dissipates mitochondrial membrane potential and maintains redox homeostasis in mitochondria during abiotic stress.

Lee CP, Maksaev G, Jensen GS, Murcha MW, Wilson ME, Fricker M, Hell R, Haswell ES, Millar AH, Sweetlove LJ.

Plant J. 2016 Dec;88(5):809-825. doi: 10.1111/tpj.13301. Epub 2016 Nov 3.

9.

Isolation of Tonoplast Vesicles from Tomato Fruit Pericarp.

Snowden CJ, Thomas B, Baxter CJ, Smith JAC, Sweetlove LJ.

Bio Protoc. 2015 Dec 20;5(24). pii: e1686. doi: 10.21769/BioProtoc.1686.

10.

Inference and Prediction of Metabolic Network Fluxes.

Nikoloski Z, Perez-Storey R, Sweetlove LJ.

Plant Physiol. 2015 Nov;169(3):1443-55. doi: 10.1104/pp.15.01082. Epub 2015 Sep 21.

11.

A Method of Accounting for Enzyme Costs in Flux Balance Analysis Reveals Alternative Pathways and Metabolite Stores in an Illuminated Arabidopsis Leaf.

Cheung CY, Ratcliffe RG, Sweetlove LJ.

Plant Physiol. 2015 Nov;169(3):1671-82. doi: 10.1104/pp.15.00880. Epub 2015 Aug 11.

12.

Heterologous expression of mitochondria-targeted microbial nitrilase enzymes increases cyanide tolerance in Arabidopsis.

Molojwane E, Adams N, Sweetlove LJ, Ingle RA.

Plant Biol (Stuttg). 2015 Jul;17(4):922-6. doi: 10.1111/plb.12323. Epub 2015 Apr 9.

PMID:
25711239
13.

A tonoplast Glu/Asp/GABA exchanger that affects tomato fruit amino acid composition.

Snowden CJ, Thomas B, Baxter CJ, Smith JA, Sweetlove LJ.

Plant J. 2015 Mar;81(5):651-60. doi: 10.1111/tpj.12766.

14.

The 'mitoflash' probe cpYFP does not respond to superoxide.

Schwarzländer M, Wagner S, Ermakova YG, Belousov VV, Radi R, Beckman JS, Buettner GR, Demaurex N, Duchen MR, Forman HJ, Fricker MD, Gems D, Halestrap AP, Halliwell B, Jakob U, Johnston IG, Jones NS, Logan DC, Morgan B, Müller FL, Nicholls DG, Remington SJ, Schumacker PT, Winterbourn CC, Sweetlove LJ, Meyer AJ, Dick TP, Murphy MP.

Nature. 2014 Oct 23;514(7523):E12-4. doi: 10.1038/nature13858. No abstract available.

15.

Mitochondrial Band-7 family proteins: scaffolds for respiratory chain assembly?

Gehl B, Sweetlove LJ.

Front Plant Sci. 2014 Apr 8;5:141. doi: 10.3389/fpls.2014.00141. eCollection 2014. Review.

16.

A Diel Flux Balance Model Captures Interactions between Light and Dark Metabolism during Day-Night Cycles in C3 and Crassulacean Acid Metabolism Leaves.

Cheung CY, Poolman MG, Fell DA, Ratcliffe RG, Sweetlove LJ.

Plant Physiol. 2014 Jun;165(2):917-929. Epub 2014 Mar 4.

17.

Metabolic flux phenotype of tobacco hairy roots engineered for increased geraniol production.

Masakapalli SK, Ritala A, Dong L, van der Krol AR, Oksman-Caldentey KM, Ratcliffe RG, Sweetlove LJ.

Phytochemistry. 2014 Mar;99:73-85. doi: 10.1016/j.phytochem.2013.12.007. Epub 2014 Jan 25.

PMID:
24472392
18.

An Arabidopsis stomatin-like protein affects mitochondrial respiratory supercomplex organization.

Gehl B, Lee CP, Bota P, Blatt MR, Sweetlove LJ.

Plant Physiol. 2014 Mar;164(3):1389-400. doi: 10.1104/pp.113.230383. Epub 2014 Jan 14.

19.

Systems analysis of metabolic phenotypes: what have we learnt?

Sweetlove LJ, Obata T, Fernie AR.

Trends Plant Sci. 2014 Apr;19(4):222-30. doi: 10.1016/j.tplants.2013.09.005. Epub 2013 Oct 16.

PMID:
24139444
20.

Increased β-cyanoalanine nitrilase activity improves cyanide tolerance and assimilation in Arabidopsis.

O'Leary B, Preston GM, Sweetlove LJ.

Mol Plant. 2014 Jan;7(1):231-43. doi: 10.1093/mp/sst110. Epub 2013 Jul 3.

21.

A method for accounting for maintenance costs in flux balance analysis improves the prediction of plant cell metabolic phenotypes under stress conditions.

Cheung CY, Williams TC, Poolman MG, Fell DA, Ratcliffe RG, Sweetlove LJ.

Plant J. 2013 Sep;75(6):1050-61. doi: 10.1111/tpj.12252. Epub 2013 Aug 6.

22.

Modelling metabolic CO₂ evolution--a fresh perspective on respiration.

Sweetlove LJ, Williams TC, Cheung CY, Ratcliffe RG.

Plant Cell Environ. 2013 Sep;36(9):1631-40. doi: 10.1111/pce.12105. Epub 2013 May 6.

23.

Transcriptomic analysis of the role of carboxylic acids in metabolite signaling in Arabidopsis leaves.

Finkemeier I, König AC, Heard W, Nunes-Nesi A, Pham PA, Leister D, Fernie AR, Sweetlove LJ.

Plant Physiol. 2013 May;162(1):239-53. doi: 10.1104/pp.113.214114. Epub 2013 Mar 13.

24.

The spatial organization of metabolism within the plant cell.

Sweetlove LJ, Fernie AR.

Annu Rev Plant Biol. 2013;64:723-46. doi: 10.1146/annurev-arplant-050312-120233. Epub 2013 Jan 16. Review.

PMID:
23330793
25.

Metabolic engineering of tomato fruit organic acid content guided by biochemical analysis of an introgression line.

Morgan MJ, Osorio S, Gehl B, Baxter CJ, Kruger NJ, Ratcliffe RG, Fernie AR, Sweetlove LJ.

Plant Physiol. 2013 Jan;161(1):397-407. doi: 10.1104/pp.112.209619. Epub 2012 Nov 19.

26.

Mitochondrial 'flashes': a radical concept repHined.

Schwarzländer M, Murphy MP, Duchen MR, Logan DC, Fricker MD, Halestrap AP, Müller FL, Rizzuto R, Dick TP, Meyer AJ, Sweetlove LJ.

Trends Cell Biol. 2012 Oct;22(10):503-8. doi: 10.1016/j.tcb.2012.07.007. Epub 2012 Aug 20. Review.

PMID:
22917552
27.

Mitochondrial cysteine synthase complex regulates O-acetylserine biosynthesis in plants.

Wirtz M, Beard KF, Lee CP, Boltz A, Schwarzländer M, Fuchs C, Meyer AJ, Heeg C, Sweetlove LJ, Ratcliffe RG, Hell R.

J Biol Chem. 2012 Aug 10;287(33):27941-7. doi: 10.1074/jbc.M112.372656. Epub 2012 Jun 22.

28.

Pulsing of membrane potential in individual mitochondria: a stress-induced mechanism to regulate respiratory bioenergetics in Arabidopsis.

Schwarzländer M, Logan DC, Johnston IG, Jones NS, Meyer AJ, Fricker MD, Sweetlove LJ.

Plant Cell. 2012 Mar;24(3):1188-201. doi: 10.1105/tpc.112.096438. Epub 2012 Mar 6.

29.

Metabolic recovery of Arabidopsis thaliana roots following cessation of oxidative stress.

Lehmann M, Laxa M, Sweetlove LJ, Fernie AR, Obata T.

Metabolomics. 2012 Feb;8(1):143-153. Epub 2011 Mar 12.

30.

The impact of impaired mitochondrial function on retrograde signalling: a meta-analysis of transcriptomic responses.

Schwarzländer M, König AC, Sweetlove LJ, Finkemeier I.

J Exp Bot. 2012 Feb;63(4):1735-50. doi: 10.1093/jxb/err374. Epub 2011 Nov 30.

PMID:
22131156
31.

Capturing metabolite channeling in metabolic flux phenotypes.

Williams TC, Sweetlove LJ, Ratcliffe RG.

Plant Physiol. 2011 Nov;157(3):981-4. doi: 10.1104/pp.111.184887. Epub 2011 Sep 6. No abstract available.

33.

Metabolic control and regulation of the tricarboxylic acid cycle in photosynthetic and heterotrophic plant tissues.

Araújo WL, Nunes-Nesi A, Nikoloski Z, Sweetlove LJ, Fernie AR.

Plant Cell Environ. 2012 Jan;35(1):1-21. doi: 10.1111/j.1365-3040.2011.02332.x. Epub 2011 Jun 20. Review.

34.

Proteins of diverse function and subcellular location are lysine acetylated in Arabidopsis.

Finkemeier I, Laxa M, Miguet L, Howden AJ, Sweetlove LJ.

Plant Physiol. 2011 Apr;155(4):1779-90. doi: 10.1104/pp.110.171595. Epub 2011 Feb 10.

35.

Flux-balance modeling of plant metabolism.

Sweetlove LJ, Ratcliffe RG.

Front Plant Sci. 2011 Aug 11;2:38. doi: 10.3389/fpls.2011.00038. eCollection 2011.

36.

The phosphoproteome of Arabidopsis plants lacking the oxidative signal-inducible1 (OXI1) protein kinase.

Howden AJ, Salek M, Miguet L, Pullen M, Thomas B, Knight MR, Sweetlove LJ.

New Phytol. 2011 Apr;190(1):49-56. doi: 10.1111/j.1469-8137.2010.03582.x. Epub 2010 Dec 22.

37.

Alteration of mitochondrial protein complexes in relation to metabolic regulation under short-term oxidative stress in Arabidopsis seedlings.

Obata T, Matthes A, Koszior S, Lehmann M, Araújo WL, Bock R, Sweetlove LJ, Fernie AR.

Phytochemistry. 2011 Jul;72(10):1081-91. doi: 10.1016/j.phytochem.2010.11.003. Epub 2010 Dec 10.

PMID:
21146842
38.

A genome-scale metabolic model accurately predicts fluxes in central carbon metabolism under stress conditions.

Williams TC, Poolman MG, Howden AJ, Schwarzlander M, Fell DA, Ratcliffe RG, Sweetlove LJ.

Plant Physiol. 2010 Sep;154(1):311-23. doi: 10.1104/pp.110.158535. Epub 2010 Jul 6.

39.

ROS signalling--specificity is required.

Møller IM, Sweetlove LJ.

Trends Plant Sci. 2010 Jul;15(7):370-4. doi: 10.1016/j.tplants.2010.04.008.

PMID:
20605736
40.

Not just a circle: flux modes in the plant TCA cycle.

Sweetlove LJ, Beard KF, Nunes-Nesi A, Fernie AR, Ratcliffe RG.

Trends Plant Sci. 2010 Aug;15(8):462-70. doi: 10.1016/j.tplants.2010.05.006. Epub 2010 Jun 16. Review.

PMID:
20554469
41.

The metabolic response of Arabidopsis roots to oxidative stress is distinct from that of heterotrophic cells in culture and highlights a complex relationship between the levels of transcripts, metabolites, and flux.

Lehmann M, Schwarzländer M, Obata T, Sirikantaramas S, Burow M, Olsen CE, Tohge T, Fricker MD, Møller BL, Fernie AR, Sweetlove LJ, Laxa M.

Mol Plant. 2009 May;2(3):390-406. doi: 10.1093/mp/ssn080. Epub 2008 Dec 26.

42.

A genome-scale metabolic model of Arabidopsis and some of its properties.

Poolman MG, Miguet L, Sweetlove LJ, Fell DA.

Plant Physiol. 2009 Nov;151(3):1570-81. doi: 10.1104/pp.109.141267. Epub 2009 Sep 15.

43.

Mitochondria biogenesis via Lon1 selective proteolysis: who dares to live for ever?

Rigas S, Daras G, Sweetlove LJ, Hatzopoulos P.

Plant Signal Behav. 2009 Mar;4(3):221-4. No abstract available.

44.

The NADPH-dependent thioredoxin system constitutes a functional backup for cytosolic glutathione reductase in Arabidopsis.

Marty L, Siala W, Schwarzländer M, Fricker MD, Wirtz M, Sweetlove LJ, Meyer Y, Meyer AJ, Reichheld JP, Hell R.

Proc Natl Acad Sci U S A. 2009 Jun 2;106(22):9109-14. doi: 10.1073/pnas.0900206106. Epub 2009 May 18.

45.

Monitoring the in vivo redox state of plant mitochondria: effect of respiratory inhibitors, abiotic stress and assessment of recovery from oxidative challenge.

Schwarzländer M, Fricker MD, Sweetlove LJ.

Biochim Biophys Acta. 2009 May;1787(5):468-75. doi: 10.1016/j.bbabio.2009.01.020. Epub 2009 Feb 3.

46.

The role of malate in plant homeostasis.

Finkemeier I, Sweetlove LJ.

F1000 Biol Rep. 2009 Jun 29;1:47. doi: 10.3410/B1-47.

47.

Role of Lon1 protease in post-germinative growth and maintenance of mitochondrial function in Arabidopsis thaliana.

Rigas S, Daras G, Laxa M, Marathias N, Fasseas C, Sweetlove LJ, Hatzopoulos P.

New Phytol. 2009;181(3):588-600. doi: 10.1111/j.1469-8137.2008.02701.x. Epub 2008 Dec 8.

48.

Confocal imaging of glutathione redox potential in living plant cells.

Schwarzländer M, Fricker MD, Müller C, Marty L, Brach T, Novak J, Sweetlove LJ, Hell R, Meyer AJ.

J Microsc. 2008 Aug;231(2):299-316. doi: 10.1111/j.1365-2818.2008.02030.x.

49.

Metabolic network fluxes in heterotrophic Arabidopsis cells: stability of the flux distribution under different oxygenation conditions.

Williams TC, Miguet L, Masakapalli SK, Kruger NJ, Sweetlove LJ, Ratcliffe RG.

Plant Physiol. 2008 Oct;148(2):704-18. doi: 10.1104/pp.108.125195. Epub 2008 Jul 30.

50.

Decrease in manganese superoxide dismutase leads to reduced root growth and affects tricarboxylic acid cycle flux and mitochondrial redox homeostasis.

Morgan MJ, Lehmann M, Schwarzländer M, Baxter CJ, Sienkiewicz-Porzucek A, Williams TC, Schauer N, Fernie AR, Fricker MD, Ratcliffe RG, Sweetlove LJ, Finkemeier I.

Plant Physiol. 2008 May;147(1):101-14. doi: 10.1104/pp.107.113613. Epub 2008 Mar 12.

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