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Items: 1 to 50 of 65

1.

Epitope mapping and structural basis for the recognition of phosphorylated tau by the anti-tau antibody AT8.

Malia TJ, Teplyakov A, Ernst R, Wu SJ, Lacy ER, Liu X, Vandermeeren M, Mercken M, Luo J, Sweet RW, Gilliland GL.

Proteins. 2016 Apr;84(4):427-34. doi: 10.1002/prot.24988. Epub 2016 Feb 5.

2.

Protein crystallization with microseed matrix screening: application to human germline antibody Fabs.

Obmolova G, Malia TJ, Teplyakov A, Sweet RW, Gilliland GL.

Acta Crystallogr F Struct Biol Commun. 2014 Aug;70(Pt 8):1107-15. doi: 10.1107/S2053230X14012552. Epub 2014 Jul 23.

3.

Second antibody modeling assessment (AMA-II).

Almagro JC, Teplyakov A, Luo J, Sweet RW, Kodangattil S, Hernandez-Guzman F, Gilliland GL.

Proteins. 2014 Aug;82(8):1553-62. doi: 10.1002/prot.24567. Epub 2014 Apr 26.

PMID:
24668560
4.

Structure and specificity of an antibody targeting a proteolytically cleaved IgG hinge.

Malia TJ, Teplyakov A, Brezski RJ, Luo J, Kinder M, Sweet RW, Almagro JC, Jordan RE, Gilliland GL.

Proteins. 2014 Aug;82(8):1656-67. doi: 10.1002/prot.24545. Epub 2014 Apr 16.

PMID:
24638881
5.

IgG variable region and VH CDR3 diversity in unimmunized mice analyzed by massively parallel sequencing.

Lu J, Panavas T, Thys K, Aerssens J, Naso M, Fisher J, Rycyzyn M, Sweet RW.

Mol Immunol. 2014 Feb;57(2):274-83. doi: 10.1016/j.molimm.2013.09.008. Epub 2013 Nov 8.

PMID:
24211535
6.

Lateral clustering of TLR3:dsRNA signaling units revealed by TLR3ecd:3Fabs quaternary structure.

Luo J, Obmolova G, Malia TJ, Wu SJ, Duffy KE, Marion JD, Bell JK, Ge P, Zhou ZH, Teplyakov A, Zhao Y, Lamb RJ, Jordan JL, San Mateo LR, Sweet RW, Gilliland GL.

J Mol Biol. 2012 Aug 3;421(1):112-24. doi: 10.1016/j.jmb.2012.05.006. Epub 2012 May 9.

7.

De novo selection of high-affinity antibodies from synthetic fab libraries displayed on phage as pIX fusion proteins.

Shi L, Wheeler JC, Sweet RW, Lu J, Luo J, Tornetta M, Whitaker B, Reddy R, Brittingham R, Borozdina L, Chen Q, Amegadzie B, Knight DM, Almagro JC, Tsui P.

J Mol Biol. 2010 Mar 26;397(2):385-96. doi: 10.1016/j.jmb.2010.01.034. Epub 2010 Jan 28.

PMID:
20114051
8.

Dermokine: an extensively differentially spliced gene expressed in epithelial cells.

Naso MF, Liang B, Huang CC, Song XY, Shahied-Arruda L, Belkowski SM, D'Andrea MR, Polkovitch DA, Lawrence DR, Griswold DE, Sweet RW, Amegadzie BY.

J Invest Dermatol. 2007 Jul;127(7):1622-31. Epub 2007 Mar 22.

9.

Stimulation of non-Hodgkin's lymphoma via HVEM: an alternate and safe way to increase Fas-induced apoptosis and improve tumor immunogenicity.

Costello RT, Mallet F, Barbarat B, Schiano De Colella JM, Sainty D, Sweet RW, Truneh A, Olive D.

Leukemia. 2003 Dec;17(12):2500-7.

PMID:
14562115
10.

Progressive epitope-blocked panning of a phage library for isolation of human RSV antibodies.

Tsui P, Tornetta MA, Ames RS, Silverman C, Porter T, Weston C, Griego S, Sweet RW.

J Immunol Methods. 2002 May 1;263(1-2):123-32.

PMID:
12009209
11.

CD4 mAb induced apoptosis of peripheral T cells: multiparameter subpopulation analysis by flow cytometry using Attractors.

Fishman-Lobell J, Tsui P, Reddy M, DiPrinzio R, Eichman C, Sweet RW, Truneh A.

J Immunol Methods. 2001 Nov 1;257(1-2):71-82.

PMID:
11687240
12.
13.

Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates.

Kwong PD, Wyatt R, Majeed S, Robinson J, Sweet RW, Sodroski J, Hendrickson WA.

Structure. 2000 Dec 15;8(12):1329-39. Erratum in: Structure Fold Des 2001 Feb 7;9(2):following R32.

14.

Modification of the Fc region of a primatized IgG antibody to human CD4 retains its ability to modulate CD4 receptors but does not deplete CD4(+) T cells in chimpanzees.

Newman R, Hariharan K, Reff M, Anderson DR, Braslawsky G, Santoro D, Hanna N, Bugelski PJ, Brigham-Burke M, Crysler C, Gagnon RC, Dal Monte P, Doyle ML, Hensley PC, Reddy MP, Sweet RW, Truneh A.

Clin Immunol. 2001 Feb;98(2):164-74.

PMID:
11161972
15.

Reciprocal expression of the TNF family receptor herpes virus entry mediator and its ligand LIGHT on activated T cells: LIGHT down-regulates its own receptor.

Morel Y, Schiano de Colella JM, Harrop J, Deen KC, Holmes SD, Wattam TA, Khandekar SS, Truneh A, Sweet RW, Gastaut JA, Olive D, Costello RT.

J Immunol. 2000 Oct 15;165(8):4397-404.

16.

Measurement of protein interaction bioenergetics: application to structural variants of anti-sCD4 antibody.

Doyle ML, Brigham-Burke M, Blackburn MN, Brooks IS, Smith TM, Newman R, Reff M, Stafford WF 3rd, Sweet RW, Truneh A, Hensley P, O'Shannessy DJ.

Methods Enzymol. 2000;323:207-30.

PMID:
10944754
17.

Energetics of the HIV gp120-CD4 binding reaction.

Myszka DG, Sweet RW, Hensley P, Brigham-Burke M, Kwong PD, Hendrickson WA, Wyatt R, Sodroski J, Doyle ML.

Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):9026-31.

18.

Elimination of Fc receptor-dependent effector functions of a modified IgG4 monoclonal antibody to human CD4.

Reddy MP, Kinney CA, Chaikin MA, Payne A, Fishman-Lobell J, Tsui P, Dal Monte PR, Doyle ML, Brigham-Burke MR, Anderson D, Reff M, Newman R, Hanna N, Sweet RW, Truneh A.

J Immunol. 2000 Feb 15;164(4):1925-33.

19.

Probability analysis of variational crystallization and its application to gp120, the exterior envelope glycoprotein of type 1 human immunodeficiency virus (HIV-1).

Kwong PD, Wyatt R, Desjardins E, Robinson J, Culp JS, Hellmig BD, Sweet RW, Sodroski J, Hendrickson WA.

J Biol Chem. 1999 Feb 12;274(7):4115-23.

20.

The antigenic structure of the HIV gp120 envelope glycoprotein.

Wyatt R, Kwong PD, Desjardins E, Sweet RW, Robinson J, Hendrickson WA, Sodroski JG.

Nature. 1998 Jun 18;393(6686):705-11.

PMID:
9641684
21.

Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody.

Kwong PD, Wyatt R, Robinson J, Sweet RW, Sodroski J, Hendrickson WA.

Nature. 1998 Jun 18;393(6686):648-59.

22.

Kinetic and structural analysis of mutant CD4 receptors that are defective in HIV gp120 binding.

Wu H, Myszka DG, Tendian SW, Brouillette CG, Sweet RW, Chaiken IM, Hendrickson WA.

Proc Natl Acad Sci U S A. 1996 Dec 24;93(26):15030-5.

23.

Isolation of a neutralizing human RSV antibody from a dominant, non-neutralizing immune repertoire by epitope-blocked panning.

Tsui P, Tornetta MA, Ames RS, Bankosky BC, Griego S, Silverman C, Porter T, Moore G, Sweet RW.

J Immunol. 1996 Jul 15;157(2):772-80.

PMID:
8752928
24.
25.

Interdomain communication of T-cell CD4 studied by absorbance and fluorescence difference spectroscopy measurements of urea-induced unfolding.

Tendian SW, Myszka DG, Sweet RW, Chaiken IM, Brouillette CG.

Biochemistry. 1995 May 16;34(19):6464-74.

PMID:
7756278
26.

Structures of an HIV and MHC binding fragment from human CD4 as refined in two crystal lattices.

Ryu SE, Truneh A, Sweet RW, Hendrickson WA.

Structure. 1994 Jan 15;2(1):59-74.

PMID:
8075984
27.
28.

Human immunodeficiency virus type 2 envelope glycoprotein: differential CD4 interactions of soluble gp120 versus the assembled envelope complex.

Mulligan MJ, Ritter GD Jr, Chaikin MA, Yamshchikov GV, Kumar P, Hahn BH, Sweet RW, Compans RW.

Virology. 1992 Mar;187(1):233-41.

PMID:
1736526
29.

Down-regulation of beta-adrenergic receptors by pindolol in Gs alpha-transfected S49 cyc- murine lymphoma cells.

Gonzales JM, O'Donnell JK, Stadel JM, Sweet RW, Molinoff PB.

J Neurochem. 1992 Mar;58(3):1093-1103.

PMID:
1310718
30.

Immunization with soluble murine CD4 induces an anti-self antibody response without causing impairment of immune function.

Cassatt DR, Sweet RW, Arthos JA, Truneh A.

J Immunol. 1991 Sep 1;147(5):1470-6.

PMID:
1880414
31.

Variants of the human high-affinity receptor (Fc gamma RI) for immunoglobulin G.

Chaikin MA, Sweet RW, Sylvester DR, Bergsma DJ.

Gene. 1991 Aug 15;104(2):285-6.

PMID:
1717350
32.

CD4: its structure, role in immune function and AIDS pathogenesis, and potential as a pharmacological target.

Sweet RW, Truneh A, Hendrickson WA.

Curr Opin Biotechnol. 1991 Aug;2(4):622-33. Review.

PMID:
1367682
33.

Expression and characterization of the long and short splice variants of GS alpha in S49 cyc- cells.

O'Donnell JK, Sweet RW, Stadel JM.

Mol Pharmacol. 1991 Jun;39(6):702-10.

PMID:
1646945
34.

Binding of soluble CD4 proteins to human immunodeficiency virus type 1 and infected cells induces release of envelope glycoprotein gp120.

Hart TK, Kirsh R, Ellens H, Sweet RW, Lambert DM, Petteway SR Jr, Leary J, Bugelski PJ.

Proc Natl Acad Sci U S A. 1991 Mar 15;88(6):2189-93.

35.

Envelope glycoproteins from biologically diverse isolates of immunodeficiency viruses have widely different affinities for CD4.

Ivey-Hoyle M, Culp JS, Chaikin MA, Hellmig BD, Matthews TJ, Sweet RW, Rosenberg M.

Proc Natl Acad Sci U S A. 1991 Jan 15;88(2):512-6.

36.

Crystal structure of an HIV-binding recombinant fragment of human CD4.

Ryu SE, Kwong PD, Truneh A, Porter TG, Arthos J, Rosenberg M, Dai XP, Xuong NH, Axel R, Sweet RW, et al.

Nature. 1990 Nov 29;348(6300):419-26.

38.

Molecular characteristics of recombinant human CD4 as deduced from polymorphic crystals.

Kwong PD, Ryu SE, Hendrickson WA, Axel R, Sweet RM, Folena-Wasserman G, Hensley P, Sweet RW.

Proc Natl Acad Sci U S A. 1990 Aug;87(16):6423-7.

39.

Soluble recombinant CD4--a potential therapeutic agent for HIV infection.

Rosenberg M, Bugelski PJ, Fong KL, Drutz DJ, Sweet RW, Webb DD.

Biotherapy. 1990;2(2):107-18. Review. No abstract available.

PMID:
2205260
40.

The genetic analysis of the HIV envelope binding domain on CD4.

Arthos J, Deen KC, Shatzman A, Truneh A, Rosenberg M, Sweet RW.

Ann N Y Acad Sci. 1990;616:116-24.

PMID:
2078013
41.

Protein and carbohydrate structural analysis of a recombinant soluble CD4 receptor by mass spectrometry.

Carr SA, Hemling ME, Folena-Wasserman G, Sweet RW, Anumula K, Barr JR, Huddleston MJ, Taylor P.

J Biol Chem. 1989 Dec 15;264(35):21286-95. Erratum in: J Biol Chem 1990 Feb 25;265(6):3585.

42.

Functional human CD4 protein produced in milk of transgenic mice.

Yu SH, Deen KC, Lee E, Hennighausen L, Sweet RW, Rosenberg M, Westphal H.

Mol Biol Med. 1989 Aug;6(4):255-61.

PMID:
2482919
43.

Structural features of CD4 required for binding to HIV.

Ibegbu CC, Kennedy MS, Maddon PJ, Deen KC, Hicks D, Sweet RW, McDougal JS.

J Immunol. 1989 Apr 1;142(7):2250-6.

PMID:
2538505
44.

Soluble CD4 blocks the infectivity of diverse strains of HIV and SIV for T cells and monocytes but not for brain and muscle cells.

Clapham PR, Weber JN, Whitby D, McIntosh K, Dalgleish AG, Maddon PJ, Deen KC, Sweet RW, Weiss RA.

Nature. 1989 Jan 26;337(6205):368-70.

PMID:
2536142
45.

DHFR coamplification of t-PA in DHFR+ bovine endothelial cells: in vitro characterization of the purified serine protease.

Connors RW, Sweet RW, Noveral JP, Pfarr DS, Trill JJ, Shebuski RJ, Berkowitz BA, Williams D, Franklin S, Reff ME.

DNA. 1988 Nov;7(9):651-61.

PMID:
3147883
46.

Gene transactivation mediated by the TAT gene of human immunodeficiency virus in transgenic mice.

Khillan JS, Deen KC, Yu SH, Sweet RW, Rosenberg M, Westphal H.

Nucleic Acids Res. 1988 Feb 25;16(4):1423-30.

47.

A soluble form of CD4 (T4) protein inhibits AIDS virus infection.

Deen KC, McDougal JS, Inacker R, Folena-Wasserman G, Arthos J, Rosenberg J, Maddon PJ, Axel R, Sweet RW.

Nature. 1988 Jan 7;331(6151):82-4.

PMID:
3257544
48.

Microinjection of the ras oncogene protein into nonestablished rat embryo fibroblasts.

Sullivan NF, Sweet RW, Rosenberg M, Feramisco JR.

Cancer Res. 1986 Dec;46(12 Pt 1):6427-32.

50.

Purification and characterization of human H-ras proteins expressed in Escherichia coli.

Gross M, Sweet RW, Sathe G, Yokoyama S, Fasano O, Goldfarb M, Wigler M, Rosenberg M.

Mol Cell Biol. 1985 May;5(5):1015-24.

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