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Items: 1 to 50 of 61

1.

Effects of antibiotics on the pharmacokinetics of indoxyl sulfate, a nephro-cardiovascular toxin.

Luo SS, Yu CP, Hsieh YW, Chao PL, Sweet DH, Hou YC, Lin SP.

Xenobiotica. 2019 Sep 4:1-5. doi: 10.1080/00498254.2019.1660433. [Epub ahead of print]

PMID:
31448977
2.

Multi-modal antidepressant-like action of 6- and 7-chloro-2-aminodihydroquinazolines in the mouse tail suspension test.

Iyer KA, Alix K, Eltit JM, Solis E Jr, Pan X, Argade MD, Khatri S, De Felice LJ, Sweet DH, Schulte MK, Dukat M.

Psychopharmacology (Berl). 2019 Jul;236(7):2093-2104. doi: 10.1007/s00213-019-05203-5. Epub 2019 Feb 25.

PMID:
30805668
3.

Building a schizophrenia genetic network: transcription factor 4 regulates genes involved in neuronal development and schizophrenia risk.

Xia H, Jahr FM, Kim NK, Xie L, Shabalin AA, Bryois J, Sweet DH, Kronfol MM, Palasuberniam P, McRae M, Riley BP, Sullivan PF, van den Oord EJ, McClay JL.

Hum Mol Genet. 2018 Sep 15;27(18):3246-3256. doi: 10.1093/hmg/ddy222.

4.

Organic solute carrier 22 (SLC22) family: Potential for interactions with food, herbal/dietary supplements, endogenous compounds, and drugs.

Lai RE, Jay CE, Sweet DH.

J Food Drug Anal. 2018 Apr;26(2S):S45-S60. doi: 10.1016/j.jfda.2018.03.002. Epub 2018 Mar 24. Review.

5.

Determination of l-glutamic acid and γ-aminobutyric acid in mouse brain tissue utilizing GC-MS/MS.

Farthing CA, Farthing DE, Gress RE, Sweet DH.

J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Nov 15;1068-1069:64-70. doi: 10.1016/j.jchromb.2017.10.020. Epub 2017 Oct 9.

PMID:
29031110
6.

A new chemotype inhibitor for the human organic cation transporter 3 (hOCT3).

Pan X, Iyer KA, Liu H, Sweet DH, Dukat M.

Bioorg Med Chem Lett. 2017 Sep 15;27(18):4440-4445. doi: 10.1016/j.bmcl.2017.08.008. Epub 2017 Aug 5.

PMID:
28811134
7.

Identification of OAT1/OAT3 as Contributors to Cisplatin Toxicity.

Hu S, Leblanc AF, Gibson AA, Hong KW, Kim JY, Janke LJ, Li L, Vasilyeva A, Finkelstein DB, Sprowl JA, Sweet DH, Schlatter E, Ciarimboli G, Schellens J, Baker SD, Pabla N, Sparreboom A.

Clin Transl Sci. 2017 Sep;10(5):412-420. doi: 10.1111/cts.12480. Epub 2017 Jul 8.

8.

Multiple blood-brain barrier transport mechanisms limit bumetanide accumulation, and therapeutic potential, in the mammalian brain.

Römermann K, Fedrowitz M, Hampel P, Kaczmarek E, Töllner K, Erker T, Sweet DH, Löscher W.

Neuropharmacology. 2017 May 1;117:182-194. doi: 10.1016/j.neuropharm.2017.02.006. Epub 2017 Feb 10.

PMID:
28192112
9.

Effects of nonsteroidal anti-inflammatory drugs on the renal excretion of indoxyl sulfate, a nephro-cardiovascular toxin, in rats.

Yu CP, Sweet DH, Peng YH, Hsieh YW, Chao PL, Hou YC, Lin SP.

Eur J Pharm Sci. 2017 Apr 1;101:66-70. doi: 10.1016/j.ejps.2017.02.007. Epub 2017 Feb 7.

PMID:
28185988
10.

Green tea inhibited the elimination of nephro-cardiovascular toxins and deteriorated the renal function in rats with renal failure.

Peng YH, Sweet DH, Lin SP, Yu CP, Lee Chao PD, Hou YC.

Sci Rep. 2015 Nov 10;5:16226. doi: 10.1038/srep16226.

11.

"Target-Site" Drug Metabolism and Transport.

Foti RS, Tyndale RF, Garcia KL, Sweet DH, Nagar S, Sharan S, Rock DA.

Drug Metab Dispos. 2015 Aug;43(8):1156-68. doi: 10.1124/dmd.115.064576. Epub 2015 May 18.

PMID:
25986849
12.

Cumulative organic anion transporter-mediated drug-drug interaction potential of multiple components in salvia miltiorrhiza (danshen) preparations.

Wang L, Venitz J, Sweet DH.

Pharm Res. 2014 Dec;31(12):3503-14. doi: 10.1007/s11095-014-1437-9. Epub 2014 Jun 25.

PMID:
24962510
13.

The kidney and uremic toxin removal: glomerulus or tubule?

Masereeuw R, Mutsaers HA, Toyohara T, Abe T, Jhawar S, Sweet DH, Lowenstein J.

Semin Nephrol. 2014 Mar;34(2):191-208. doi: 10.1016/j.semnephrol.2014.02.010. Epub 2014 Feb 18.

PMID:
24780473
14.

The furan fatty acid metabolite CMPF is elevated in diabetes and induces β cell dysfunction.

Prentice KJ, Luu L, Allister EM, Liu Y, Jun LS, Sloop KW, Hardy AB, Wei L, Jia W, Fantus IG, Sweet DH, Sweeney G, Retnakaran R, Dai FF, Wheeler MB.

Cell Metab. 2014 Apr 1;19(4):653-66. doi: 10.1016/j.cmet.2014.03.008.

15.

Inhibition of human organic cation transporters by the alkaloids matrine and oxymatrine.

Pan X, Wang L, Gründemann D, Sweet DH.

Fitoterapia. 2014 Jan;92:206-10. doi: 10.1016/j.fitote.2013.11.009. Epub 2013 Nov 27.

PMID:
24291757
16.

Simultaneous determination of gallic acid and gentisic acid in organic anion transporter expressing cells by liquid chromatography-tandem mass spectrometry.

Wang L, Halquist MS, Sweet DH.

J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Oct 15;937:91-6. doi: 10.1016/j.jchromb.2013.08.024. Epub 2013 Aug 26.

PMID:
24022056
17.

The anthraquinone drug rhein potently interferes with organic anion transporter-mediated renal elimination.

Wang L, Pan X, Sweet DH.

Biochem Pharmacol. 2013 Oct 1;86(7):991-6. doi: 10.1016/j.bcp.2013.08.016. Epub 2013 Aug 22.

PMID:
23973525
18.

Interaction of Ethambutol with human organic cation transporters of the SLC22 family indicates potential for drug-drug interactions during antituberculosis therapy.

Pan X, Wang L, Gründemann D, Sweet DH.

Antimicrob Agents Chemother. 2013 Oct;57(10):5053-9. doi: 10.1128/AAC.01255-13. Epub 2013 Aug 5.

19.

Expression and function of organic cation and anion transporters (SLC22 family) in the CNS.

Farthing CA, Sweet DH.

Curr Pharm Des. 2014;20(10):1472-86. Review.

PMID:
23789957
20.

Interaction of Natural Dietary and Herbal Anionic Compounds and Flavonoids with Human Organic Anion Transporters 1 (SLC22A6), 3 (SLC22A8), and 4 (SLC22A11).

Wang L, Sweet DH.

Evid Based Complement Alternat Med. 2013;2013:612527. doi: 10.1155/2013/612527. Epub 2013 Mar 21.

21.

Human organic cation transporters 1 (SLC22A1), 2 (SLC22A2), and 3 (SLC22A3) as disposition pathways for fluoroquinolone antimicrobials.

Mulgaonkar A, Venitz J, Gründemann D, Sweet DH.

Antimicrob Agents Chemother. 2013 Jun;57(6):2705-11. doi: 10.1128/AAC.02289-12. Epub 2013 Apr 1.

22.

Sex-dependent expression of Oat3 (Slc22a8) and Oat1 (Slc22a6) proteins in murine kidneys.

Breljak D, Brzica H, Sweet DH, Anzai N, Sabolic I.

Am J Physiol Renal Physiol. 2013 Apr 15;304(8):F1114-26. doi: 10.1152/ajprenal.00201.2012. Epub 2013 Feb 6.

24.

Renal organic anion transporters (SLC22 family): expression, regulation, roles in toxicity, and impact on injury and disease.

Wang L, Sweet DH.

AAPS J. 2013 Jan;15(1):53-69. doi: 10.1208/s12248-012-9413-y. Epub 2012 Oct 9. Review.

25.

Potential for food-drug interactions by dietary phenolic acids on human organic anion transporters 1 (SLC22A6), 3 (SLC22A8), and 4 (SLC22A11).

Wang L, Sweet DH.

Biochem Pharmacol. 2012 Oct 15;84(8):1088-95. doi: 10.1016/j.bcp.2012.07.027. Epub 2012 Jul 31.

PMID:
22877817
26.

Active Hydrophilic Components of the Medicinal Herb Salvia miltiorrhiza (Danshen) Potently Inhibit Organic Anion Transporters 1 (Slc22a6) and 3 (Slc22a8).

Wang L, Sweet DH.

Evid Based Complement Alternat Med. 2012;2012:872458. doi: 10.1155/2012/872458. Epub 2012 Jul 15.

27.

Fluoroquinolone disposition: identification of the contribution of renal secretory and reabsorptive drug transporters.

Mulgaonkar A, Venitz J, Sweet DH.

Expert Opin Drug Metab Toxicol. 2012 May;8(5):553-69. doi: 10.1517/17425255.2012.674512. Epub 2012 Mar 22. Review.

PMID:
22435536
28.

Linkage of organic anion transporter-1 to metabolic pathways through integrated "omics"-driven network and functional analysis.

Ahn SY, Jamshidi N, Mo ML, Wu W, Eraly SA, Dnyanmote A, Bush KT, Gallegos TF, Sweet DH, Palsson BØ, Nigam SK.

J Biol Chem. 2011 Sep 9;286(36):31522-31. doi: 10.1074/jbc.M111.272534. Epub 2011 Jul 12.

29.

Physiological and molecular characterization of aristolochic acid transport by the kidney.

Dickman KG, Sweet DH, Bonala R, Ray T, Wu A.

J Pharmacol Exp Ther. 2011 Aug;338(2):588-97. doi: 10.1124/jpet.111.180984. Epub 2011 May 5.

30.

Organic anion transporter 6 (Slc22a20) specificity and Sertoli cell-specific expression provide new insight on potential endogenous roles.

Schnabolk GW, Gupta B, Mulgaonkar A, Kulkarni M, Sweet DH.

J Pharmacol Exp Ther. 2010 Sep 1;334(3):927-35. doi: 10.1124/jpet.110.168765. Epub 2010 Jun 2.

31.

Organic anion transporters: discovery, pharmacology, regulation and roles in pathophysiology.

VanWert AL, Gionfriddo MR, Sweet DH.

Biopharm Drug Dispos. 2010 Jan;31(1):1-71. doi: 10.1002/bdd.693. Review.

PMID:
19953504
32.

Activation of protein kinase Czeta increases OAT1 (SLC22A6)- and OAT3 (SLC22A8)-mediated transport.

Barros SA, Srimaroeng C, Perry JL, Walden R, Dembla-Rajpal N, Sweet DH, Pritchard JB.

J Biol Chem. 2009 Jan 30;284(5):2672-9. doi: 10.1074/jbc.M808078200. Epub 2008 Nov 21.

33.

Two CES1 gene mutations lead to dysfunctional carboxylesterase 1 activity in man: clinical significance and molecular basis.

Zhu HJ, Patrick KS, Yuan HJ, Wang JS, Donovan JL, DeVane CL, Malcolm R, Johnson JA, Youngblood GL, Sweet DH, Langaee TY, Markowitz JS.

Am J Hum Genet. 2008 Jun;82(6):1241-8. doi: 10.1016/j.ajhg.2008.04.015. Epub 2008 May 15.

34.

Organic anion transporter 3 (oat3/slc22a8) interacts with carboxyfluoroquinolones, and deletion increases systemic exposure to ciprofloxacin.

Vanwert AL, Srimaroeng C, Sweet DH.

Mol Pharmacol. 2008 Jul;74(1):122-31. doi: 10.1124/mol.107.042853. Epub 2008 Apr 1.

35.

Organic anion transporter 3 (Oat3/Slc22a8) knockout mice exhibit altered clearance and distribution of penicillin G.

Vanwert AL, Bailey RM, Sweet DH.

Am J Physiol Renal Physiol. 2007 Oct;293(4):F1332-41. Epub 2007 Aug 8.

37.

Kinase signaling pathways regulate fine tuning of transporter activity.

Sweet DH.

Am J Physiol Renal Physiol. 2007 Jul;293(1):F20. Epub 2007 Apr 4. No abstract available.

38.
39.
40.

Transport of estrone sulfate by the novel organic anion transporter Oat6 (Slc22a20).

Schnabolk GW, Youngblood GL, Sweet DH.

Am J Physiol Renal Physiol. 2006 Aug;291(2):F314-21. Epub 2006 Feb 14.

41.

The dietary polyphenol ellagic acid is a potent inhibitor of hOAT1.

Whitley AC, Sweet DH, Walle T.

Drug Metab Dispos. 2005 Aug;33(8):1097-100. Epub 2005 May 3.

PMID:
15870380
42.

Organic anion transporter (Slc22a) family members as mediators of toxicity.

Sweet DH.

Toxicol Appl Pharmacol. 2005 May 1;204(3):198-215. Review.

PMID:
15845414
43.

Organic anion transport in choroid plexus from wild-type and organic anion transporter 3 (Slc22a8)-null mice.

Sykes D, Sweet DH, Lowes S, Nigam SK, Pritchard JB, Miller DS.

Am J Physiol Renal Physiol. 2004 May;286(5):F972-8. Epub 2003 Dec 23.

44.

Identification and functional assessment of the novel murine organic anion transporter Oat5 (Slc22a19) expressed in kidney.

Youngblood GL, Sweet DH.

Am J Physiol Renal Physiol. 2004 Aug;287(2):F236-44. Epub 2004 Apr 6.

45.

Stoichiometry of organic anion/dicarboxylate exchange in membrane vesicles from rat renal cortex and hOAT1-expressing cells.

Aslamkhan A, Han YH, Walden R, Sweet DH, Pritchard JB.

Am J Physiol Renal Physiol. 2003 Oct;285(4):F775-83. Epub 2003 Jul 1.

46.

Organic anion transporter 3 (Slc22a8) is a dicarboxylate exchanger indirectly coupled to the Na+ gradient.

Sweet DH, Chan LM, Walden R, Yang XP, Miller DS, Pritchard JB.

Am J Physiol Renal Physiol. 2003 Apr;284(4):F763-9. Epub 2002 Dec 17.

47.

Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3 (Slc22a8)) knockout mice.

Sweet DH, Miller DS, Pritchard JB, Fujiwara Y, Beier DR, Nigam SK.

J Biol Chem. 2002 Jul 26;277(30):26934-43. Epub 2002 May 13.

48.

Mercapturic acids (N-acetylcysteine S-conjugates) as endogenous substrates for the renal organic anion transporter-1.

Pombrio JM, Giangreco A, Li L, Wempe MF, Anders MW, Sweet DH, Pritchard JB, Ballatori N.

Mol Pharmacol. 2001 Nov;60(5):1091-9.

PMID:
11641438
49.

Ventricular choline transport: a role for organic cation transporter 2 expressed in choroid plexus.

Sweet DH, Miller DS, Pritchard JB.

J Biol Chem. 2001 Nov 9;276(45):41611-9. Epub 2001 Sep 11.

50.

The organic anion transporter family: from physiology to ontogeny and the clinic.

Sweet DH, Bush KT, Nigam SK.

Am J Physiol Renal Physiol. 2001 Aug;281(2):F197-205. Review.

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