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Restoration of functional full-length dystrophin after intramuscular transplantation of Foamy Virus-transduced myoblasts.

Meng J, Sweeney N, Doreste B, Muntoni F, McClure M, Morgan J.

Hum Gene Ther. 2019 Dec 5. doi: 10.1089/hum.2019.224. [Epub ahead of print]


Hypoxia Suppresses High Fat Diet-Induced Steatosis And Development Of Hepatic Adenomas.

Sweeney NW, Gomes CJ, De Armond R, Centuori SM, Parthasarathy S, Martinez JD.

Hypoxia (Auckl). 2019 Oct 21;7:53-63. doi: 10.2147/HP.S217569. eCollection 2019.


A Randomized, Controlled Trial of the Analytic and Diagnostic Performance of Singleton and Trio, Rapid Genome and Exome Sequencing in Ill Infants.

Kingsmore SF, Cakici JA, Clark MM, Gaughran M, Feddock M, Batalov S, Bainbridge MN, Carroll J, Caylor SA, Clarke C, Ding Y, Ellsworth K, Farnaes L, Hildreth A, Hobbs C, James K, Kint CI, Lenberg J, Nahas S, Prince L, Reyes I, Salz L, Sanford E, Schols P, Sweeney N, Tokita M, Veeraraghavan N, Watkins K, Wigby K, Wong T, Chowdhury S, Wright MS, Dimmock D; RCIGM Investigators.

Am J Hum Genet. 2019 Oct 3;105(4):719-733. doi: 10.1016/j.ajhg.2019.08.009. Epub 2019 Sep 26.


Facial Transplantation for an Irreparable Central and Lower Face Injury: A Modernized Approach to a Classic Challenge.

Kantar RS, Ceradini DJ, Gelb BE, Levine JP, Staffenberg DA, Saadeh PB, Flores RL, Sweeney NG, Bernstein GL, Rodriguez ED.

Plast Reconstr Surg. 2019 Aug;144(2):264e-283e. doi: 10.1097/PRS.0000000000005885. Review.


Rapid Whole Genome Sequencing Has Clinical Utility in Children in the PICU.

Sanford EF, Clark MM, Farnaes L, Williams MR, Perry JC, Ingulli EG, Sweeney NM, Doshi A, Gold JJ, Briggs B, Bainbridge MN, Feddock M, Watkins K, Chowdhury S, Nahas SA, Dimmock DP, Kingsmore SF, Coufal NG; RCIGM Investigators.

Pediatr Crit Care Med. 2019 Nov;20(11):1007-1020. doi: 10.1097/PCC.0000000000002056.


Clinical Utility of Advanced Microbiology Testing Tools.

Miller MB, Atrzadeh F, Burnham CA, Cavalieri S, Dunn J, Jones S, Mathews C, McNult P, Meduri J, Newhouse C, Newton D, Oberholzer M, Osiecki J, Pedersen D, Sweeney N, Whitfield N, Campos J; ASM Clinical and Public Health Microbiology Committee and the ASM Corporate Council.

J Clin Microbiol. 2019 Aug 26;57(9). pii: e00495-19. doi: 10.1128/JCM.00495-19. Print 2019 Sep. Review.


Just culture: It's more than policy.

Paradiso L, Sweeney N.

Nurs Manage. 2019 Jun;50(6):38-45. doi: 10.1097/ No abstract available.


Intraperitoneal injections as an alternative method for micro-CT contrast enhanced detection of murine liver tumors.

Sweeney N, Marchant S, Martinez JD.

Biotechniques. 2019 May;66(5):214-217. doi: 10.2144/btn-2018-0162.


Diagnosis of genetic diseases in seriously ill children by rapid whole-genome sequencing and automated phenotyping and interpretation.

Clark MM, Hildreth A, Batalov S, Ding Y, Chowdhury S, Watkins K, Ellsworth K, Camp B, Kint CI, Yacoubian C, Farnaes L, Bainbridge MN, Beebe C, Braun JJA, Bray M, Carroll J, Cakici JA, Caylor SA, Clarke C, Creed MP, Friedman J, Frith A, Gain R, Gaughran M, George S, Gilmer S, Gleeson J, Gore J, Grunenwald H, Hovey RL, Janes ML, Lin K, McDonagh PD, McBride K, Mulrooney P, Nahas S, Oh D, Oriol A, Puckett L, Rady Z, Reese MG, Ryu J, Salz L, Sanford E, Stewart L, Sweeney N, Tokita M, Van Der Kraan L, White S, Wigby K, Williams B, Wong T, Wright MS, Yamada C, Schols P, Reynders J, Hall K, Dimmock D, Veeraraghavan N, Defay T, Kingsmore SF.

Sci Transl Med. 2019 Apr 24;11(489). pii: eaat6177. doi: 10.1126/scitranslmed.aat6177.


Candida auris arriving on our shores: an Australian microbiology laboratory's experience.

Chew SM, Sweeney N, Kidd SE, Reed C.

Pathology. 2019 Jun;51(4):431-433. doi: 10.1016/j.pathol.2019.01.009. Epub 2019 Apr 17. No abstract available.


Comparing outcomes of biopsy-proven anti-neutrophil cytoplasmic autoantibody-associated glomerulonephritis patients treated with cyclophosphamide in the 20th and 21st centuries: a 23-year study.

Whatmough S, Fernandez S, Sweeney N, Howell L, Dhaygude A.

Clin Kidney J. 2019 Feb;12(1):42-48. doi: 10.1093/ckj/sfy084. Epub 2018 Sep 11.


PPARγ Interaction with UBR5/ATMIN Promotes DNA Repair to Maintain Endothelial Homeostasis.

Li CG, Mahon C, Sweeney NM, Verschueren E, Kantamani V, Li D, Hennigs JK, Marciano DP, Diebold I, Abu-Halawa O, Elliott M, Sa S, Guo F, Wang L, Cao A, Guignabert C, Sollier J, Nickel NP, Kaschwich M, Cimprich KA, Rabinovitch M.

Cell Rep. 2019 Jan 29;26(5):1333-1343.e7. doi: 10.1016/j.celrep.2019.01.013.


A-C Estrogens as Potent and Selective Estrogen Receptor-Beta Agonists (SERBAs) to Enhance Memory Consolidation under Low-Estrogen Conditions.

Hanson AM, Perera KLIS, Kim J, Pandey RK, Sweeney N, Lu X, Imhoff A, Mackinnon AC, Wargolet AJ, Van Hart RM, Frick KM, Donaldson WA, Sem DS.

J Med Chem. 2018 Jun 14;61(11):4720-4738. doi: 10.1021/acs.jmedchem.7b01601. Epub 2018 Jun 4.


Rapid whole-genome sequencing decreases infant morbidity and cost of hospitalization.

Farnaes L, Hildreth A, Sweeney NM, Clark MM, Chowdhury S, Nahas S, Cakici JA, Benson W, Kaplan RH, Kronick R, Bainbridge MN, Friedman J, Gold JJ, Ding Y, Veeraraghavan N, Dimmock D, Kingsmore SF.

NPJ Genom Med. 2018 Apr 4;3:10. doi: 10.1038/s41525-018-0049-4. eCollection 2018.


The effect of an active shooter response intervention on hospital employees' response knowledge, perceived program usefulness, and perceived organizational preparedness.

Landry G, Zimbro KS, Morgan MK, Maduro RS, Snyder T, Sweeney NL.

J Healthc Risk Manag. 2018 Jul;38(1):9-14. doi: 10.1002/jhrm.21313. Epub 2018 Apr 2. Erratum in: J Healthc Risk Manag. 2018 Oct;38(2):61.


The case for early use of rapid whole-genome sequencing in management of critically ill infants: late diagnosis of Coffin-Siris syndrome in an infant with left congenital diaphragmatic hernia, congenital heart disease, and recurrent infections.

Sweeney NM, Nahas SA, Chowdhury S, Campo MD, Jones MC, Dimmock DP, Kingsmore SF; RCIGM Investigators.

Cold Spring Harb Mol Case Stud. 2018 Jun 1;4(3). pii: a002469. doi: 10.1101/mcs.a002469. Print 2018 Jun.


The NSIGHT1-randomized controlled trial: rapid whole-genome sequencing for accelerated etiologic diagnosis in critically ill infants.

Petrikin JE, Cakici JA, Clark MM, Willig LK, Sweeney NM, Farrow EG, Saunders CJ, Thiffault I, Miller NA, Zellmer L, Herd SM, Holmes AM, Batalov S, Veeraraghavan N, Smith LD, Dimmock DP, Leeder JS, Kingsmore SF.

NPJ Genom Med. 2018 Feb 9;3:6. doi: 10.1038/s41525-018-0045-8. eCollection 2018.


Dual Specificity Phosphatase 5-Substrate Interaction: A Mechanistic Perspective.

Kutty RG, Talipov MR, Bongard RD, Lipinski RAJ, Sweeney NL, Sem DS, Rathore R, Ramchandran R.

Compr Physiol. 2017 Sep 12;7(4):1449-1461. doi: 10.1002/cphy.c170007. Review.


Delivery of large transgene cassettes by foamy virus vector.

Sweeney NP, Meng J, Patterson H, Morgan JE, McClure M.

Sci Rep. 2017 Aug 14;7(1):8085. doi: 10.1038/s41598-017-08312-3.


Perioperative Nursing Management of Donor and Recipient Patients Undergoing Face Transplantation.

Sweeney N, Allen K, Miller B, Nolan T, Sheerin K.

AORN J. 2017 Jul;106(1):8-19. doi: 10.1016/j.aorn.2017.05.004.


Serendipitous discovery of light-induced (In Situ) formation of an Azo-bridged dimeric sulfonated naphthol as a potent PTP1B inhibitor.

Bongard RD, Lepley M, Thakur K, Talipov MR, Nayak J, Lipinski RAJ, Bohl C, Sweeney N, Ramchandran R, Rathore R, Sem DS.

BMC Biochem. 2017 May 31;18(1):10. doi: 10.1186/s12858-017-0083-3.


Barriers to the Use of Assistive Devices in Patient Handling.

Noble NL, Sweeney NL.

Workplace Health Saf. 2018 Jan;66(1):41-48. doi: 10.1177/2165079917697216. Epub 2017 May 9.


Amphetamines promote mitochondrial dysfunction and DNA damage in pulmonary hypertension.

Chen PI, Cao A, Miyagawa K, Tojais NF, Hennigs JK, Li CG, Sweeney NM, Inglis AS, Wang L, Li D, Ye M, Feldman BJ, Rabinovitch M.

JCI Insight. 2017 Jan 26;2(2):e90427. doi: 10.1172/jci.insight.90427.


Docking into Mycobacterium tuberculosis Thioredoxin Reductase Protein Yields Pyrazolone Lead Molecules for Methicillin-Resistant Staphylococcus aureus.

Sweeney NL, Lipker L, Hanson AM, Bohl CJ, Engel KE, Kalous KS, Stemper ME, Sem DS, Schwan WR.

Antibiotics (Basel). 2017 Jan 28;6(1). pii: E4. doi: 10.3390/antibiotics6010004.


Expression of transcription factors divides retinal ganglion cells into distinct classes.

Sweeney NT, James KN, Nistorica A, Lorig-Roach RM, Feldheim DA.

J Comp Neurol. 2019 Jan 1;527(1):225-235. doi: 10.1002/cne.24172. Epub 2017 Mar 10.


Total Face, Eyelids, Ears, Scalp, and Skeletal Subunit Transplant: A Reconstructive Solution for the Full Face and Total Scalp Burn.

Sosin M, Ceradini DJ, Levine JP, Hazen A, Staffenberg DA, Saadeh PB, Flores RL, Sweeney NG, Bernstein GL, Rodriguez ED.

Plast Reconstr Surg. 2016 Jul;138(1):205-19. doi: 10.1097/PRS.0000000000002322.


Rapid and Efficient Stable Gene Transfer to Mesenchymal Stromal Cells Using a Modified Foamy Virus Vector.

Sweeney NP, Regan C, Liu J, Galleu A, Dazzi F, Lindemann D, Rupar CA, McClure MO.

Mol Ther. 2016 Aug;24(7):1227-36. doi: 10.1038/mt.2016.91. Epub 2016 May 2.


Total Face, Eyelids, Ears, Scalp, and Skeletal Subunit Transplant Research Procurement: A Translational Simulation Model.

Sosin M, Ceradini DJ, Hazen A, Sweeney NG, Brecht LE, Levine JP, Staffenberg DA, Saadeh PB, Bernstein GL, Rodriguez ED.

Plast Reconstr Surg. 2016 May;137(5):845e-54e. doi: 10.1097/PRS.0000000000002326.


Determination of Sequences Required for Human Endogenous Retrovirus K Transduction and Its Recognition by Foreign Retroviral Virions.

Erlwein O, Sweeney NP, de Leon R, Wills G, Robinson MJ, McClure MO.

J Virol. 2015 Dec 30;90(6):3243-6. doi: 10.1128/JVI.02731-15.


Preparing for a face transplant: development of a comprehensive nursing educational program.

Sweeney N, Calame-Mars G, Dojlidko D, Frank-Bader M, Keller R, Waterman J.

Prog Transplant. 2015 Dec;25(4):316-20. doi: 10.7182/pit2015899.


Benzothiazole and Pyrrolone Flavivirus Inhibitors Targeting the Viral Helicase.

Sweeney NL, Hanson AM, Mukherjee S, Ndjomou J, Geiss BJ, Steel JJ, Frankowski KJ, Li K, Schoenen FJ, Frick DN.

ACS Infect Dis. 2015 Mar 13;1(3):140-148.


Simultaneously Targeting the NS3 Protease and Helicase Activities for More Effective Hepatitis C Virus Therapy.

Ndjomou J, Corby MJ, Sweeney NL, Hanson AM, Aydin C, Ali A, Schiffer CA, Li K, Frankowski KJ, Schoenen FJ, Frick DN.

ACS Chem Biol. 2015 Aug 21;10(8):1887-96. doi: 10.1021/acschembio.5b00101. Epub 2015 May 22.


Discovery of the 2-phenyl-4,5,6,7-Tetrahydro-1H-indole as a novel anti-hepatitis C virus targeting scaffold.

Andreev IA, Manvar D, Barreca ML, Belov DS, Basu A, Sweeney NL, Ratmanova NK, Lukyanenko ER, Manfroni G, Cecchetti V, Frick DN, Altieri A, Kaushik-Basu N, Kurkin AV.

Eur J Med Chem. 2015;96:250-8. doi: 10.1016/j.ejmech.2015.04.022. Epub 2015 Apr 10.


Ephrin-As are required for the topographic mapping but not laminar choice of physiologically distinct RGC types.

Sweeney NT, James KN, Sales EC, Feldheim DA.

Dev Neurobiol. 2015 Jun;75(6):584-93. doi: 10.1002/dneu.22265. Epub 2015 Feb 18.


Novel regulatory roles of cAMP receptor proteins in fast-growing environmental mycobacteria.

Aung HL, Dixon LL, Smith LJ, Sweeney NP, Robson JR, Berney M, Buxton RS, Green J, Cook GM.

Microbiology. 2015 Mar;161(Pt 3):648-61. doi: 10.1099/mic.0.000015. Epub 2014 Dec 18.


How postdocs benefit from building a union.

Cain B, Budke JM, Wood KJ, Sweeney NT, Schwessinger B.

Elife. 2014 Nov 21;3. doi: 10.7554/eLife.05614. No abstract available.


Ebselen inhibits hepatitis C virus NS3 helicase binding to nucleic acid and prevents viral replication.

Mukherjee S, Weiner WS, Schroeder CE, Simpson DS, Hanson AM, Sweeney NL, Marvin RK, Ndjomou J, Kolli R, Isailovic D, Schoenen FJ, Frick DN.

ACS Chem Biol. 2014 Oct 17;9(10):2393-403. doi: 10.1021/cb500512z. Epub 2014 Aug 15.


Multifidus muscle size and percentage thickness changes among patients with unilateral chronic low back pain (CLBP) and healthy controls in prone and standing.

Sweeney N, O'Sullivan C, Kelly G.

Man Ther. 2014 Oct;19(5):433-9. doi: 10.1016/j.math.2014.04.009. Epub 2014 May 9.


Tbr2 is required to generate a neural circuit mediating the pupillary light reflex.

Sweeney NT, Tierney H, Feldheim DA.

J Neurosci. 2014 Apr 16;34(16):5447-53. doi: 10.1523/JNEUROSCI.0035-14.2014.


Dendritic and axonal targeting patterns of a genetically-specified class of retinal ganglion cells that participate in image-forming circuits.

Triplett JW, Wei W, Gonzalez C, Sweeney NT, Huberman AD, Feller MB, Feldheim DA.

Neural Dev. 2014 Feb 5;9:2. doi: 10.1186/1749-8104-9-2.


Letter: follow-up practices in coeliac disease--intestinal biopsy after child-to-adult transition might be useful; authors' reply.

Sharkey LM, Corbett G, Currie E, Lee J, Sweeney N, Woodward JM.

Aliment Pharmacol Ther. 2014 Jan;39(2):235-6. doi: 10.1111/apt.12576. No abstract available.


Optimising delivery of care in coeliac disease - comparison of the benefits of repeat biopsy and serological follow-up.

Sharkey LM, Corbett G, Currie E, Lee J, Sweeney N, Woodward JM.

Aliment Pharmacol Ther. 2013 Nov;38(10):1278-91. doi: 10.1111/apt.12510. Epub 2013 Oct 5.


Aurintricarboxylic acid modulates the affinity of hepatitis C virus NS3 helicase for both nucleic acid and ATP.

Shadrick WR, Mukherjee S, Hanson AM, Sweeney NL, Frick DN.

Biochemistry. 2013 Sep 10;52(36):6151-9. doi: 10.1021/bi4006495. Epub 2013 Aug 26.


Hepatitis C Virus NS3 Helicase Inhibitor Discovery.

Li K, Frankowski KJ, Hanson AM, Ndjomou J, Shanahan MA, Mukherjee S, Kolli R, Shadrick WR, Sweeney NL, Belon CA, Neuenswander B, Ferguson J, Aubé J, Schoenen FJ, Blagg BSJ, Frick DN.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2011 Dec 16 [updated 2013 Mar 14].


Primuline derivatives that mimic RNA to stimulate hepatitis C virus NS3 helicase-catalyzed ATP hydrolysis.

Sweeney NL, Shadrick WR, Mukherjee S, Li K, Frankowski KJ, Schoenen FJ, Frick DN.

J Biol Chem. 2013 Jul 5;288(27):19949-57. doi: 10.1074/jbc.M113.463166. Epub 2013 May 23.


University of California: union improves postdocs' rights.

Sweeney N.

Nature. 2012 Nov 15;491(7424):333. doi: 10.1038/491333c. No abstract available.


Fluorescent primuline derivatives inhibit hepatitis C virus NS3-catalyzed RNA unwinding, peptide hydrolysis and viral replicase formation.

Ndjomou J, Kolli R, Mukherjee S, Shadrick WR, Hanson AM, Sweeney NL, Bartczak D, Li K, Frankowski KJ, Schoenen FJ, Frick DN.

Antiviral Res. 2012 Nov;96(2):245-55. doi: 10.1016/j.antiviral.2012.08.006. Epub 2012 Aug 25.


Postdocs: the power of unions.

Sweeney N.

Science. 2012 Jun 29;336(6089):1638. doi: 10.1126/science.336.6089.1638-a. No abstract available.


Identification and analysis of hepatitis C virus NS3 helicase inhibitors using nucleic acid binding assays.

Mukherjee S, Hanson AM, Shadrick WR, Ndjomou J, Sweeney NL, Hernandez JJ, Bartczak D, Li K, Frankowski KJ, Heck JA, Arnold LA, Schoenen FJ, Frick DN.

Nucleic Acids Res. 2012 Sep 1;40(17):8607-21. Epub 2012 Jun 27.

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