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Items: 1 to 50 of 160

1.

Dorsal Ear Skin Window for Intravital Imaging and Functional Analysis of Lymphangiogenesis.

Kilarski WW, Güç E, Swartz MA.

Methods Mol Biol. 2018;1846:261-277. doi: 10.1007/978-1-4939-8712-2_17.

PMID:
30242765
2.

Lymphatic vessel density is associated with CD8+ T cell infiltration and immunosuppressive factors in human melanoma.

Bordry N, Broggi MAS, de Jonge K, Schaeuble K, Gannon PO, Foukas PG, Danenberg E, Romano E, Baumgaertner P, Fankhauser M, Wald N, Cagnon L, Abed-Maillard S, Hajjami HM, Murray T, Ioannidou K, Letovanec I, Yan P, Michielin O, Matter M, Swartz MA, Speiser DE.

Oncoimmunology. 2018 May 31;7(8):e1462878. doi: 10.1080/2162402X.2018.1462878. eCollection 2018.

3.

Nanoparticle Conjugation of Human Papillomavirus 16 E7-long Peptides Enhances Therapeutic Vaccine Efficacy against Solid Tumors in Mice.

Galliverti G, Tichet M, Domingos-Pereira S, Hauert S, Nardelli-Haefliger D, Swartz MA, Hanahan D, Wullschleger S.

Cancer Immunol Res. 2018 Aug 21. doi: 10.1158/2326-6066.CIR-18-0166. [Epub ahead of print]

PMID:
30131378
4.

Improving Efficacy and Safety of Agonistic Anti-CD40 Antibody Through Extracellular Matrix Affinity.

Ishihara J, Ishihara A, Potin L, Hosseinchi P, Fukunaga K, Damo M, Gajewski TF, Swartz MA, Hubbell JA.

Mol Cancer Ther. 2018 Aug 10. doi: 10.1158/1535-7163.MCT-18-0091. [Epub ahead of print]

PMID:
30097487
5.

Immune Checkpoint Ligand PD-L1 is Upregulated in Pulmonary Lymphangioleiomyomatosis (LAM).

Maisel K, Merrilees MJ, Atochina-Vasserman EN, Lian L, Obraztsova K, Rue R, Vasserman AN, Zuo N, Angel LF, Gow AJ, Kang I, Wight TN, Eruslanov E, Swartz MA, Krymskaya VP.

Am J Respir Cell Mol Biol. 2018 Aug 10. doi: 10.1165/rcmb.2018-0123OC. [Epub ahead of print]

PMID:
30095976
6.

First Successful Experimental Implantation of a Drainage Device to Reduce Lymphoedema in a Rat Lymphoedema Model.

Triacca V, Pisano M, Lessert C, Petit B, Bouzourene K, Nahimana A, Vozenin MC, Stergiopulos N, Swartz MA, Mazzolai L.

Eur J Vasc Endovasc Surg. 2018 May 24. pii: S1078-5884(18)30257-0. doi: 10.1016/j.ejvs.2018.04.014. [Epub ahead of print]

7.

Matrix-binding checkpoint immunotherapies enhance antitumor efficacy and reduce adverse events.

Ishihara J, Fukunaga K, Ishihara A, Larsson HM, Potin L, Hosseinchi P, Galliverti G, Swartz MA, Hubbell JA.

Sci Transl Med. 2017 Nov 8;9(415). pii: eaan0401. doi: 10.1126/scitranslmed.aan0401.

PMID:
29118259
8.

Oxidation-sensitive polymersomes as vaccine nanocarriers enhance humoral responses against Lassa virus envelope glycoprotein.

Galan-Navarro C, Rincon-Restrepo M, Zimmer G, Ollmann Saphire E, Hubbell JA, Hirosue S, Swartz MA, Kunz S.

Virology. 2017 Dec;512:161-171. doi: 10.1016/j.virol.2017.09.013. Epub 2017 Sep 28.

PMID:
28963882
9.

Tumor lymphangiogenesis promotes T cell infiltration and potentiates immunotherapy in melanoma.

Fankhauser M, Broggi MAS, Potin L, Bordry N, Jeanbart L, Lund AW, Da Costa E, Hauert S, Rincon-Restrepo M, Tremblay C, Cabello E, Homicsko K, Michielin O, Hanahan D, Speiser DE, Swartz MA.

Sci Transl Med. 2017 Sep 13;9(407). pii: eaal4712. doi: 10.1126/scitranslmed.aal4712.

PMID:
28904226
10.

Exploiting lymphatic vessels for immunomodulation: Rationale, opportunities, and challenges.

Maisel K, Sasso MS, Potin L, Swartz MA.

Adv Drug Deliv Rev. 2017 May 15;114:43-59. doi: 10.1016/j.addr.2017.07.005. Epub 2017 Jul 8. Review.

11.

Local induction of lymphangiogenesis with engineered fibrin-binding VEGF-C promotes wound healing by increasing immune cell trafficking and matrix remodeling.

Güç E, Briquez PS, Foretay D, Fankhauser MA, Hubbell JA, Kilarski WW, Swartz MA.

Biomaterials. 2017 Jul;131:160-175. doi: 10.1016/j.biomaterials.2017.03.033. Epub 2017 Mar 25.

12.

Vaccine nanocarriers: Coupling intracellular pathways and cellular biodistribution to control CD4 vs CD8 T cell responses.

Rincon-Restrepo M, Mayer A, Hauert S, Bonner DK, Phelps EA, Hubbell JA, Swartz MA, Hirosue S.

Biomaterials. 2017 Jul;132:48-58. doi: 10.1016/j.biomaterials.2017.03.047. Epub 2017 Mar 30.

PMID:
28407494
13.

Toll-like receptor 8 agonist nanoparticles mimic immunomodulating effects of the live BCG vaccine and enhance neonatal innate and adaptive immune responses.

Dowling DJ, Scott EA, Scheid A, Bergelson I, Joshi S, Pietrasanta C, Brightman S, Sanchez-Schmitz G, Van Haren SD, Ninković J, Kats D, Guiducci C, de Titta A, Bonner DK, Hirosue S, Swartz MA, Hubbell JA, Levy O.

J Allergy Clin Immunol. 2017 Nov;140(5):1339-1350. doi: 10.1016/j.jaci.2016.12.985. Epub 2017 Mar 23.

14.

Transcellular Pathways in Lymphatic Endothelial Cells Regulate Changes in Solute Transport by Fluid Stress.

Triacca V, Güç E, Kilarski WW, Pisano M, Swartz MA.

Circ Res. 2017 Apr 28;120(9):1440-1452. doi: 10.1161/CIRCRESAHA.116.309828. Epub 2017 Jan 27.

PMID:
28130294
15.

Primary Human and Rat β-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity.

Cianciaruso C, Phelps EA, Pasquier M, Hamelin R, Demurtas D, Alibashe Ahmed M, Piemonti L, Hirosue S, Swartz MA, De Palma M, Hubbell JA, Baekkeskov S.

Diabetes. 2017 Feb;66(2):460-473. doi: 10.2337/db16-0671. Epub 2016 Nov 21.

16.

T Cells Redirected to a Minor Histocompatibility Antigen Instruct Intratumoral TNFα Expression and Empower Adoptive Cell Therapy for Solid Tumors.

Manzo T, Sturmheit T, Basso V, Petrozziello E, Hess Michelini R, Riba M, Freschi M, Elia AR, Grioni M, Curnis F, Protti MP, Schumacher TN, Debets R, Swartz MA, Corti A, Bellone M, Mondino A.

Cancer Res. 2017 Feb 1;77(3):658-671. doi: 10.1158/0008-5472.CAN-16-0725. Epub 2016 Nov 21.

17.

Connecting (T)issues: How Research in Fascia Biology Can Impact Integrative Oncology.

Langevin HM, Keely P, Mao J, Hodge LM, Schleip R, Deng G, Hinz B, Swartz MA, de Valois BA, Zick S, Findley T.

Cancer Res. 2016 Nov 1;76(21):6159-6162. Epub 2016 Oct 11. Review.

18.

Perivascular Macrophages Limit Permeability.

He H, Mack JJ, Güç E, Warren CM, Squadrito ML, Kilarski WW, Baer C, Freshman RD, McDonald AI, Ziyad S, Swartz MA, De Palma M, Iruela-Arispe ML.

Arterioscler Thromb Vasc Biol. 2016 Nov;36(11):2203-2212. Epub 2016 Sep 15.

19.

Lymphatic vessels regulate immune microenvironments in human and murine melanoma.

Lund AW, Wagner M, Fankhauser M, Steinskog ES, Broggi MA, Spranger S, Gajewski TF, Alitalo K, Eikesdal HP, Wiig H, Swartz MA.

J Clin Invest. 2016 Sep 1;126(9):3389-402. doi: 10.1172/JCI79434. Epub 2016 Aug 15.

20.

Fibronectin EDA and CpG synergize to enhance antigen-specific Th1 and cytotoxic responses.

Julier Z, de Titta A, Grimm AJ, Simeoni E, Swartz MA, Hubbell JA.

Vaccine. 2016 May 5;34(21):2453-2459. doi: 10.1016/j.vaccine.2016.03.057. Epub 2016 Mar 24.

21.

Polypropylene Sulfide Nanoparticle p24 Vaccine Promotes Dendritic Cell-Mediated Specific Immune Responses against HIV-1.

Caucheteux SM, Mitchell JP, Ivory MO, Hirosue S, Hakobyan S, Dolton G, Ladell K, Miners K, Price DA, Kan-Mitchell J, Sewell AK, Nestle F, Moris A, Karoo RO, Birchall JC, Swartz MA, Hubbel JA, Blanchet FP, Piguet V.

J Invest Dermatol. 2016 Jun;136(6):1172-81. doi: 10.1016/j.jid.2016.01.033. Epub 2016 Feb 16.

22.

Engineering opportunities in cancer immunotherapy.

Jeanbart L, Swartz MA.

Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):14467-72. doi: 10.1073/pnas.1508516112. Review.

23.

Corrigendum: Combined CSL and p53 downregulation promotes cancer-associated fibroblast activation.

Procopio MG, Laszlo C, Al Labban D, Kim DE, Bordignon P, Jo SH, Goruppi S, Menietti E, Ostano P, Ala U, Provero P, Hoetzenecker W, Neel V, Kilarski WW, Swartz MA, Brisken C, Lefort K, Dotto GP.

Nat Cell Biol. 2015 Oct;17(10):1370. doi: 10.1038/ncb3242. No abstract available.

PMID:
26419803
24.

Tissue mechanics: Cell jam.

Swartz MA.

Nat Mater. 2015 Oct;14(10):970-1. doi: 10.1038/nmat4434. No abstract available.

PMID:
26395940
25.

Nanoparticle conjugation enhances the immunomodulatory effects of intranasally delivered CpG in house dust mite-allergic mice.

Ballester M, Jeanbart L, de Titta A, Nembrini C, Marsland BJ, Hubbell JA, Swartz MA.

Sci Rep. 2015 Sep 21;5:14274. doi: 10.1038/srep14274.

26.

Combined CSL and p53 downregulation promotes cancer-associated fibroblast activation.

Procopio MG, Laszlo C, Al Labban D, Kim DE, Bordignon P, Jo SH, Goruppi S, Menietti E, Ostano P, Ala U, Provero P, Hoetzenecker W, Neel V, Kilarski WW, Swartz MA, Brisken C, Lefort K, Dotto GP.

Nat Cell Biol. 2015 Sep;17(9):1193-204. doi: 10.1038/ncb3228. Epub 2015 Aug 24. Erratum in: Nat Cell Biol. 2015 Oct;17(10):1370.

27.

ADAM17 Promotes Motility, Invasion, and Sprouting of Lymphatic Endothelial Cells.

Mężyk-Kopeć R, Wyroba B, Stalińska K, Próchnicki T, Wiatrowska K, Kilarski WW, Swartz MA, Bereta J.

PLoS One. 2015 Jul 15;10(7):e0132661. doi: 10.1371/journal.pone.0132661. eCollection 2015.

28.

6-Thioguanine-loaded polymeric micelles deplete myeloid-derived suppressor cells and enhance the efficacy of T cell immunotherapy in tumor-bearing mice.

Jeanbart L, Kourtis IC, van der Vlies AJ, Swartz MA, Hubbell JA.

Cancer Immunol Immunother. 2015 Aug;64(8):1033-46. doi: 10.1007/s00262-015-1702-8. Epub 2015 May 16.

29.

Collecting lymphatic vessel permeability facilitates adipose tissue inflammation and distribution of antigen to lymph node-homing adipose tissue dendritic cells.

Kuan EL, Ivanov S, Bridenbaugh EA, Victora G, Wang W, Childs EW, Platt AM, Jakubzick CV, Mason RJ, Gashev AA, Nussenzweig M, Swartz MA, Dustin ML, Zawieja DC, Randolph GJ.

J Immunol. 2015 Jun 1;194(11):5200-10. doi: 10.4049/jimmunol.1500221. Epub 2015 Apr 27.

30.

An in vitro model of the tumor-lymphatic microenvironment with simultaneous transendothelial and luminal flows reveals mechanisms of flow enhanced invasion.

Pisano M, Triacca V, Barbee KA, Swartz MA.

Integr Biol (Camb). 2015 May;7(5):525-33. doi: 10.1039/c5ib00085h. Epub 2015 Apr 21.

PMID:
25896438
31.

Inflammatory lymphangiogenesis in postpartum breast tissue remodeling.

Swartz MA.

J Clin Invest. 2014 Sep;124(9):3704-7. doi: 10.1172/JCI77765. Epub 2014 Aug 18.

32.

Immunomodulatory roles of lymphatic vessels in cancer progression.

Swartz MA.

Cancer Immunol Res. 2014 Aug;2(8):701-7. doi: 10.1158/2326-6066.CIR-14-0115. Review.

33.

Lymph node stromal cells acquire peptide-MHCII complexes from dendritic cells and induce antigen-specific CD4⁺ T cell tolerance.

Dubrot J, Duraes FV, Potin L, Capotosti F, Brighouse D, Suter T, LeibundGut-Landmann S, Garbi N, Reith W, Swartz MA, Hugues S.

J Exp Med. 2014 Jun 2;211(6):1153-66. doi: 10.1084/jem.20132000. Epub 2014 May 19.

34.

Long-term intravital immunofluorescence imaging of tissue matrix components with epifluorescence and two-photon microscopy.

Güç E, Fankhauser M, Lund AW, Swartz MA, Kilarski WW.

J Vis Exp. 2014 Apr 22;(86). doi: 10.3791/51388.

35.

Steady-state antigen scavenging, cross-presentation, and CD8+ T cell priming: a new role for lymphatic endothelial cells.

Hirosue S, Vokali E, Raghavan VR, Rincon-Restrepo M, Lund AW, Corthésy-Henrioud P, Capotosti F, Halin Winter C, Hugues S, Swartz MA.

J Immunol. 2014 Jun 1;192(11):5002-11. doi: 10.4049/jimmunol.1302492. Epub 2014 May 2.

36.

Enhancing efficacy of anticancer vaccines by targeted delivery to tumor-draining lymph nodes.

Jeanbart L, Ballester M, de Titta A, Corthésy P, Romero P, Hubbell JA, Swartz MA.

Cancer Immunol Res. 2014 May;2(5):436-47. doi: 10.1158/2326-6066.CIR-14-0019-T. Epub 2014 Feb 11.

37.

Introduction to the special issue on lymphangiogenesis in inflammation.

Swartz MA, Randolph GJ.

Angiogenesis. 2014 Apr;17(2):323-4. doi: 10.1007/s10456-014-9427-4. No abstract available.

PMID:
24671660
38.

Emerging roles of lymphatic endothelium in regulating adaptive immunity.

Card CM, Yu SS, Swartz MA.

J Clin Invest. 2014 Mar;124(3):943-52. doi: 10.1172/JCI73316. Epub 2014 Mar 3. Review.

39.

Growth factors engineered for super-affinity to the extracellular matrix enhance tissue healing.

Martino MM, Briquez PS, Güç E, Tortelli F, Kilarski WW, Metzger S, Rice JJ, Kuhn GA, Müller R, Swartz MA, Hubbell JA.

Science. 2014 Feb 21;343(6173):885-8. doi: 10.1126/science.1247663.

PMID:
24558160
40.

Modeling tumor microenvironments in vitro.

Wu M, Swartz MA.

J Biomech Eng. 2014 Feb;136(2):021011. doi: 10.1115/1.4026447. Review.

41.

Nanoparticle conjugation of CpG enhances adjuvancy for cellular immunity and memory recall at low dose.

de Titta A, Ballester M, Julier Z, Nembrini C, Jeanbart L, van der Vlies AJ, Swartz MA, Hubbell JA.

Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):19902-7. doi: 10.1073/pnas.1313152110. Epub 2013 Nov 18.

42.

Engineering synthetic vaccines using cues from natural immunity.

Irvine DJ, Swartz MA, Szeto GL.

Nat Mater. 2013 Nov;12(11):978-90. doi: 10.1038/nmat3775. Review.

43.

Targeting the tumor-draining lymph node with adjuvanted nanoparticles reshapes the anti-tumor immune response.

Thomas SN, Vokali E, Lund AW, Hubbell JA, Swartz MA.

Biomaterials. 2014 Jan;35(2):814-24. doi: 10.1016/j.biomaterials.2013.10.003. Epub 2013 Oct 18.

44.

VEGFR-3 neutralization inhibits ovarian lymphangiogenesis, follicle maturation, and murine pregnancy.

Rutkowski JM, Ihm JE, Lee ST, Kilarski WW, Greenwood VI, Pasquier MC, Quazzola A, Trono D, Hubbell JA, Swartz MA.

Am J Pathol. 2013 Nov;183(5):1596-1607. doi: 10.1016/j.ajpath.2013.07.031. Epub 2013 Sep 13.

45.

Optimization and regeneration kinetics of lymphatic-specific photodynamic therapy in the mouse dermis.

Kilarski WW, Muchowicz A, Wachowska M, Mężyk-Kopeć R, Golab J, Swartz MA, Nowak-Sliwinska P.

Angiogenesis. 2014 Apr;17(2):347-57. doi: 10.1007/s10456-013-9365-6. Epub 2013 Jul 28.

46.

Cooperative roles of SDF-1α and EGF gradients on tumor cell migration revealed by a robust 3D microfluidic model.

Kim BJ, Hannanta-anan P, Chau M, Kim YS, Swartz MA, Wu M.

PLoS One. 2013 Jul 15;8(7):e68422. doi: 10.1371/journal.pone.0068422. Print 2013.

47.

The promotion of endothelial cell attachment and spreading using FNIII10 fused to VEGF-A165.

Traub S, Morgner J, Martino MM, Höning S, Swartz MA, Wickström SA, Hubbell JA, Eming SA.

Biomaterials. 2013 Aug;34(24):5958-68. doi: 10.1016/j.biomaterials.2013.04.050. Epub 2013 May 14.

PMID:
23683723
48.

Peripherally administered nanoparticles target monocytic myeloid cells, secondary lymphoid organs and tumors in mice.

Kourtis IC, Hirosue S, de Titta A, Kontos S, Stegmann T, Hubbell JA, Swartz MA.

PLoS One. 2013 Apr 23;8(4):e61646. doi: 10.1371/journal.pone.0061646. Print 2013.

49.

Normal dendritic cell mobilization to lymph nodes under conditions of severe lymphatic hypoplasia.

Platt AM, Rutkowski JM, Martel C, Kuan EL, Ivanov S, Swartz MA, Randolph GJ.

J Immunol. 2013 May 1;190(9):4608-20. doi: 10.4049/jimmunol.1202600. Epub 2013 Mar 25.

50.

Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice.

Martel C, Li W, Fulp B, Platt AM, Gautier EL, Westerterp M, Bittman R, Tall AR, Chen SH, Thomas MJ, Kreisel D, Swartz MA, Sorci-Thomas MG, Randolph GJ.

J Clin Invest. 2013 Apr;123(4):1571-9. doi: 10.1172/JCI63685. Epub 2013 Mar 25.

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