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Items: 20


DNA-guided DNA cleavage at moderate temperatures by Clostridium butyricum Argonaute.

Hegge JW, Swarts DC, Chandradoss SD, Cui TJ, Kneppers J, Jinek M, Joo C, van der Oost J.

Nucleic Acids Res. 2019 Jun 20;47(11):5809-5821. doi: 10.1093/nar/gkz306.


Stirring Up the Type V Alphabet Soup.

Swarts DC.

CRISPR J. 2019 Feb;2:14-16. doi: 10.1089/crispr.2019.29044.dcs. No abstract available.


Preparation and electroporation of Cas12a/Cpf1-guide RNA complexes for introducing large gene deletions in mouse embryonic stem cells.

Kissling L, Monfort A, Swarts DC, Wutz A, Jinek M.

Methods Enzymol. 2019;616:241-263. doi: 10.1016/bs.mie.2018.10.028. Epub 2019 Jan 17.


Mechanistic Insights into the cis- and trans-Acting DNase Activities of Cas12a.

Swarts DC, Jinek M.

Mol Cell. 2019 Feb 7;73(3):589-600.e4. doi: 10.1016/j.molcel.2018.11.021. Epub 2019 Jan 10.


Cas9 versus Cas12a/Cpf1: Structure-function comparisons and implications for genome editing.

Swarts DC, Jinek M.

Wiley Interdiscip Rev RNA. 2018 May 22:e1481. doi: 10.1002/wrna.1481. [Epub ahead of print] Review.


Bacteriophage DNA glucosylation impairs target DNA binding by type I and II but not by type V CRISPR-Cas effector complexes.

Vlot M, Houkes J, Lochs SJA, Swarts DC, Zheng P, Kunne T, Mohanraju P, Anders C, Jinek M, van der Oost J, Dickman MJ, Brouns SJJ.

Nucleic Acids Res. 2018 Jan 25;46(2):873-885. doi: 10.1093/nar/gkx1264.


Prokaryotic Argonaute proteins: novel genome-editing tools?

Hegge JW, Swarts DC, van der Oost J.

Nat Rev Microbiol. 2018 Jan;16(1):5-11. doi: 10.1038/nrmicro.2017.73. Epub 2017 Jul 24. Review.


Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a.

Swarts DC, van der Oost J, Jinek M.

Mol Cell. 2017 Apr 20;66(2):221-233.e4. doi: 10.1016/j.molcel.2017.03.016.


Autonomous Generation and Loading of DNA Guides by Bacterial Argonaute.

Swarts DC, Szczepaniak M, Sheng G, Chandradoss SD, Zhu Y, Timmers EM, Zhang Y, Zhao H, Lou J, Wang Y, Joo C, van der Oost J.

Mol Cell. 2017 Mar 16;65(6):985-998.e6. doi: 10.1016/j.molcel.2017.01.033. Epub 2017 Mar 2.


Argonaute of the archaeon Pyrococcus furiosus is a DNA-guided nuclease that targets cognate DNA.

Swarts DC, Hegge JW, Hinojo I, Shiimori M, Ellis MA, Dumrongkulraksa J, Terns RM, Terns MP, van der Oost J.

Nucleic Acids Res. 2015 May 26;43(10):5120-9. doi: 10.1093/nar/gkv415. Epub 2015 Apr 29.


Effects of Argonaute on Gene Expression in Thermus thermophilus.

Swarts DC, Koehorst JJ, Westra ER, Schaap PJ, van der Oost J.

PLoS One. 2015 Apr 22;10(4):e0124880. doi: 10.1371/journal.pone.0124880. eCollection 2015.


The evolutionary journey of Argonaute proteins.

Swarts DC, Makarova K, Wang Y, Nakanishi K, Ketting RF, Koonin EV, Patel DJ, van der Oost J.

Nat Struct Mol Biol. 2014 Sep;21(9):743-53. doi: 10.1038/nsmb.2879. Review.


Prokaryotic Argonautes - variations on the RNA interference theme.

van der Oost J, Swarts DC, Jore MM.

Microb Cell. 2014 Apr 15;1(5):158-159. doi: 10.15698/mic2014.05.144.


DNA-guided DNA interference by a prokaryotic Argonaute.

Swarts DC, Jore MM, Westra ER, Zhu Y, Janssen JH, Snijders AP, Wang Y, Patel DJ, Berenguer J, Brouns SJJ, van der Oost J.

Nature. 2014 Mar 13;507(7491):258-261. doi: 10.1038/nature12971. Epub 2014 Feb 16.


Planting the seed: target recognition of short guide RNAs.

K√ľnne T, Swarts DC, Brouns SJ.

Trends Microbiol. 2014 Feb;22(2):74-83. doi: 10.1016/j.tim.2013.12.003. Epub 2014 Jan 14. Review.


Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage.

Sheng G, Zhao H, Wang J, Rao Y, Tian W, Swarts DC, van der Oost J, Patel DJ, Wang Y.

Proc Natl Acad Sci U S A. 2014 Jan 14;111(2):652-7. doi: 10.1073/pnas.1321032111. Epub 2013 Dec 27.


Complete genome sequence of Syntrophobacter fumaroxidans strain (MPOB(T)).

Plugge CM, Henstra AM, Worm P, Swarts DC, Paulitsch-Fuchs AH, Scholten JC, Lykidis A, Lapidus AL, Goltsman E, Kim E, McDonald E, Rohlin L, Crable BR, Gunsalus RP, Stams AJ, McInerney MJ.

Stand Genomic Sci. 2012 Oct 10;7(1):91-106. doi: 10.4056/sigs.2996379. Epub 2012 Sep 26.


The CRISPRs, they are a-changin': how prokaryotes generate adaptive immunity.

Westra ER, Swarts DC, Staals RH, Jore MM, Brouns SJ, van der Oost J.

Annu Rev Genet. 2012;46:311-39. doi: 10.1146/annurev-genet-110711-155447. Review.


CRISPR interference directs strand specific spacer acquisition.

Swarts DC, Mosterd C, van Passel MW, Brouns SJ.

PLoS One. 2012;7(4):e35888. doi: 10.1371/journal.pone.0035888. Epub 2012 Apr 27.


An HflX-type GTPase from Sulfolobus solfataricus binds to the 50S ribosomal subunit in all nucleotide-bound states.

Blombach F, Launay H, Zorraquino V, Swarts DC, Cabrita LD, Benelli D, Christodoulou J, Londei P, van der Oost J.

J Bacteriol. 2011 Jun;193(11):2861-7. doi: 10.1128/JB.01552-10. Epub 2011 Apr 8.

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