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Hippocampal segmentation for brains with extensive atrophy using three-dimensional convolutional neural networks.

Goubran M, Ntiri EE, Akhavein H, Holmes M, Nestor S, Ramirez J, Adamo S, Ozzoude M, Scott C, Gao F, Martel A, Swardfager W, Masellis M, Swartz R, MacIntosh B, Black SE.

Hum Brain Mapp. 2019 Oct 14. doi: 10.1002/hbm.24811. [Epub ahead of print]


APOE ɛ4, white matter hyperintensities, and cognition in Alzheimer and Lewy body dementia.

Mirza SS, Saeed U, Knight J, Ramirez J, Stuss DT, Keith J, Nestor SM, Yu D, Swardfager W, Rogaeva E, St George Hyslop P, Black SE, Masellis M; Alzheimer's Disease Neuroimaging Initiative.

Neurology. 2019 Oct 1. pii: 10.1212/WNL.0000000000008377. doi: 10.1212/WNL.0000000000008377. [Epub ahead of print]


Impact of Early Nausea on Varenicline Adherence and Smoking Cessation.

Peng AR, Swardfager W, Benowitz NL, Ahluwalia JS, Lerman C, Nollen NL, Tyndale RF.

Addiction. 2019 Sep 10. doi: 10.1111/add.14810. [Epub ahead of print]


Reciprocal Predictive Relationships between Amyloid and Tau Biomarkers in Alzheimer's Disease Progression: An Empirical Model.

Krance SH, Cogo-Moreira H, Rabin JS, Black SE, Swardfager W; Alzheimer's Disease Neuroimaging Initiative.

J Neurosci. 2019 Sep 11;39(37):7428-7437. doi: 10.1523/JNEUROSCI.1056-19.2019. Epub 2019 Jul 26.


White matter hyperintensities in vascular contributions to cognitive impairment and dementia (VCID): Knowledge gaps and opportunities.

Alber J, Alladi S, Bae HJ, Barton DA, Beckett LA, Bell JM, Berman SE, Biessels GJ, Black SE, Bos I, Bowman GL, Brai E, Brickman AM, Callahan BL, Corriveau RA, Fossati S, Gottesman RF, Gustafson DR, Hachinski V, Hayden KM, Helman AM, Hughes TM, Isaacs JD, Jefferson AL, Johnson SC, Kapasi A, Kern S, Kwon JC, Kukolja J, Lee A, Lockhart SN, Murray A, Osborn KE, Power MC, Price BR, Rhodius-Meester HFM, Rondeau JA, Rosen AC, Rosene DL, Schneider JA, Scholtzova H, Shaaban CE, Silva NCBS, Snyder HM, Swardfager W, Troen AM, van Veluw SJ, Vemuri P, Wallin A, Wellington C, Wilcock DM, Xie SX, Hainsworth AH.

Alzheimers Dement (N Y). 2019 Apr 9;5:107-117. doi: 10.1016/j.trci.2019.02.001. eCollection 2019. Review.


Plasma Sphingolipids Mediate a Relationship Between Type 2 Diabetes and Memory Outcomes in Patients with Coronary Artery Disease Undertaking Exercise.

Eakin KA, Saleem M, Herrmann N, Cogo-Moreira H, Mielke MM, Oh PI, Haughey NJ, Venkata SLV, Lanctôt KL, Swardfager W.

J Alzheimers Dis. 2019;69(3):717-727. doi: 10.3233/JAD-181203.


Birth weight, verbal cognition in early adolescence, and lexical and reading skills in late adolescence: a formal mediation analysis using a potential outcomes approach.

Silva ARD, Puglisi ML, Pompéia S, Ploubidis GB, Swardfager W, Cogo-Moreira H.

J Child Psychol Psychiatry. 2019 Jul;60(7):773-783. doi: 10.1111/jcpp.13043. Epub 2019 Mar 25.


Lower serum osteocalcin concentrations in patients with type 2 diabetes and relationships with vascular risk factors among patients with coronary artery disease.

Darwish L, Nguyen MM, Saleem M, Eakin KA, Herrmann N, Sugamori KS, Oh PI, Yang P, Mitchell J, Lanctôt KL, Swardfager W.

J Diabetes Complications. 2019 May;33(5):390-397. doi: 10.1016/j.jdiacomp.2019.01.003. Epub 2019 Jan 17.


The trajectory of balance skill development from childhood to adolescence was influenced by birthweight: a latent transition analysis in a British birth cohort.

Okuda PMM, Swardfager W, Lucio PS, Ploubidis GB, Liu T, Pangelinan M, Cogo-Moreira H.

J Clin Epidemiol. 2019 May;109:12-19. doi: 10.1016/j.jclinepi.2018.12.012. Epub 2018 Dec 17.


On Mediation Models in Clinical Neurology Studies.

Cogo-Moreira H, Swardfager W.

JAMA Neurol. 2019 Jan 1;76(1):116-117. doi: 10.1001/jamaneurol.2018.3884. No abstract available.


Soluble Epoxide Hydrolase-Derived Linoleic Acid Oxylipins in Serum Are Associated with Periventricular White Matter Hyperintensities and Vascular Cognitive Impairment.

Yu D, Hennebelle M, Sahlas DJ, Ramirez J, Gao F, Masellis M, Cogo-Moreira H, Swartz RH, Herrmann N, Chan PC, Pettersen JA, Stuss DT, Black SE, Taha AY, Swardfager W.

Transl Stroke Res. 2019 Oct;10(5):522-533. doi: 10.1007/s12975-018-0672-5. Epub 2018 Nov 15.


Rates of Screening for Breast, Colorectal, and Cervical Cancers in Older People With Cognitive Impairment or Dementia: A Meta-Analysis.

Law M, Dhillon S, Herrmann N, Friesen F, Dey AK, Li A, Ayala AP, Lenton E, Edwards JD, Swardfager W.

Gerontol Geriatr Med. 2018 Sep 18;4:2333721418799446. doi: 10.1177/2333721418799446. eCollection 2018 Jan-Dec.


The effect of exercise on resting concentrations of peripheral brain-derived neurotrophic factor (BDNF) in major depressive disorder: A meta-analysis.

Dinoff A, Herrmann N, Swardfager W, Gallagher D, Lanctôt KL.

J Psychiatr Res. 2018 Oct;105:123-131. doi: 10.1016/j.jpsychires.2018.08.021. Epub 2018 Sep 6.


Seasonal plasticity of cognition and related biological measures in adults with and without Alzheimer disease: Analysis of multiple cohorts.

Lim ASP, Gaiteri C, Yu L, Sohail S, Swardfager W, Tasaki S, Schneider JA, Paquet C, Stuss DT, Masellis M, Black SE, Hugon J, Buchman AS, Barnes LL, Bennett DA, De Jager PL.

PLoS Med. 2018 Sep 4;15(9):e1002647. doi: 10.1371/journal.pmed.1002647. eCollection 2018 Sep.


Cerebral blood flow in bipolar disorder: A systematic review.

Toma S, MacIntosh BJ, Swardfager W, Goldstein BI.

J Affect Disord. 2018 Dec 1;241:505-513. doi: 10.1016/j.jad.2018.08.040. Epub 2018 Aug 11.


A latent transition analysis of a cluster randomized controlled trial for drug use prevention.

Valente JY, Cogo-Moreira H, Swardfager W, Sanchez ZM.

J Consult Clin Psychol. 2018 Aug;86(8):657-665. doi: 10.1037/ccp0000329.


Risk of bias in randomized controlled trials of psychological treatments for bulimia nervosa and binge eating.

Trevizo JP, Hay P, Swardfager W, Cogo-Moreira H.

Ann Epidemiol. 2018 Sep;28(9):625-628.e1. doi: 10.1016/j.annepidem.2018.06.006. Epub 2018 Jul 3.


Depression in people with type 2 diabetes: current perspectives.

Darwish L, Beroncal E, Sison MV, Swardfager W.

Diabetes Metab Syndr Obes. 2018 Jul 10;11:333-343. doi: 10.2147/DMSO.S106797. eCollection 2018. Review.


Validity of the QUADAS-2 in Assessing Risk of Bias in Alzheimer's Disease Diagnostic Accuracy Studies.

Venazzi A, Swardfager W, Lam B, Siqueira JO, Herrmann N, Cogo-Moreira H.

Front Psychiatry. 2018 May 25;9:221. doi: 10.3389/fpsyt.2018.00221. eCollection 2018.


APOE-ε4 associates with hippocampal volume, learning, and memory across the spectrum of Alzheimer's disease and dementia with Lewy bodies.

Saeed U, Mirza SS, MacIntosh BJ, Herrmann N, Keith J, Ramirez J, Nestor SM, Yu Q, Knight J, Swardfager W, Potkin SG, Rogaeva E, St George-Hyslop P, Black SE, Masellis M.

Alzheimers Dement. 2018 Sep;14(9):1137-1147. doi: 10.1016/j.jalz.2018.04.005. Epub 2018 May 18.


An immunological age index in bipolar disorder: A confirmatory factor analysis of putative immunosenescence markers and associations with clinical characteristics.

Rizzo LB, Swardfager W, Maurya PK, Graiff MZ, Pedrini M, Asevedo E, Cassinelli AC, Bauer ME, Cordeiro Q, Scott J, Brietzke E, Cogo-Moreira H.

Int J Methods Psychiatr Res. 2018 Dec;27(4):e1614. doi: 10.1002/mpr.1614. Epub 2018 Apr 25.


A schizophrenia-like behavioral trait in the SHR model: Applying confirmatory factor analysis as a new statistical tool.

Peres FF, Eufrásio RÁ, Gouvêa DA, Diana MC, Santos CM, Swardfager W, Abílio VC, Cogo-Moreira H.

Prog Neuropsychopharmacol Biol Psychiatry. 2018 Jul 13;85:16-22. doi: 10.1016/j.pnpbp.2018.03.021. Epub 2018 Apr 4.


Reduced substantia innominata volume mediates contributions of microvascular and macrovascular disease to cognitive deficits in Alzheimer's disease.

Jaswal G, Swardfager W, Gao FQ, Nestor SM, Ganda A, Cogo-Moreira H, Sahlas DJ, Stuss DT, Moody A, Black SE.

Neurobiol Aging. 2018 Jun;66:23-31. doi: 10.1016/j.neurobiolaging.2018.01.025. Epub 2018 Feb 10.


Metabolic/inflammatory/vascular comorbidity in psychiatric disorders; soluble epoxide hydrolase (sEH) as a possible new target.

Swardfager W, Hennebelle M, Yu D, Hammock BD, Levitt AJ, Hashimoto K, Taha AY.

Neurosci Biobehav Rev. 2018 Apr;87:56-66. doi: 10.1016/j.neubiorev.2018.01.010. Epub 2018 Feb 2. Review.


Influence of birthweight on childhood balance: Evidence from two British birth cohorts.

Okuda PMM, Swardfager W, Ploubidis GB, Pangelinan M, Cogo-Moreira H.

Early Hum Dev. 2019 Mar;130:116-120. doi: 10.1016/j.earlhumdev.2018.01.010. Epub 2018 Feb 1.


The effect of white matter hyperintensities on verbal memory: Mediation by temporal lobe atrophy.

Swardfager W, Cogo-Moreira H, Masellis M, Ramirez J, Herrmann N, Edwards JD, Saleem M, Chan P, Yu D, Nestor SM, Scott CJM, Holmes MF, Sahlas DJ, Kiss A, Oh PI, Strother SC, Gao F, Stefanovic B, Keith J, Symons S, Swartz RH, Lanctôt KL, Stuss DT, Black SE.

Neurology. 2018 Feb 20;90(8):e673-e682. doi: 10.1212/WNL.0000000000004983. Epub 2018 Jan 26.


Effects of the brain-derived neurotropic factor variant Val66Met on cortical structure in late childhood and early adolescence.

de Araujo CM, Zugman A, Swardfager W, Belangero SIN, Ota VK, Spindola LM, Hakonarson H, Pellegrino R, Gadelha A, Salum GA, Pan PM, de Moura LM, Del Aquilla M, Picon FA, Amaro E Jr, Sato JR, Brietzke E, Grassi-Oliveira R, Rohde LAP, Miguel EC, Bressan RA, Jackowski AP.

J Psychiatr Res. 2018 Mar;98:51-58. doi: 10.1016/j.jpsychires.2017.12.008. Epub 2017 Dec 20.


Post-stroke Fatigue and Depressive Symptoms Are Differentially Related to Mobility and Cognitive Performance.

MacIntosh BJ, Edwards JD, Kang M, Cogo-Moreira H, Chen JL, Mochizuki G, Herrmann N, Swardfager W.

Front Aging Neurosci. 2017 Oct 31;9:343. doi: 10.3389/fnagi.2017.00343. eCollection 2017.


Testing Measurement Invariance across Groups of Children with and without Attention-Deficit/ Hyperactivity Disorder: Applications for Word Recognition and Spelling Tasks.

Lúcio PS, Salum G, Swardfager W, Mari JJ, Pan PM, Bressan RA, Gadelha A, Rohde LA, Cogo-Moreira H.

Front Psychol. 2017 Oct 25;8:1891. doi: 10.3389/fpsyg.2017.01891. eCollection 2017.


Assessing risk of bias in randomized controlled trials of methylphenidate for children and adolescents with attention deficit hyperactivity disorder (ADHD).

Rodrigues-Tartari R, Swardfager W, Salum GA, Rohde LA, Cogo-Moreira H.

Int J Methods Psychiatr Res. 2018 Mar;27(1). doi: 10.1002/mpr.1586. Epub 2017 Sep 4.


Peripheral lipid oxidative stress markers are related to vascular risk factors and subcortical small vessel disease.

Swardfager W, Yu D, Scola G, Cogo-Moreira H, Chan P, Zou Y, Herrmann N, Lanctôt KL, Ramirez J, Gao F, Masellis M, Swartz RH, Sahlas DJ, Chan PC, Ojeda-Lopez C, Milan-Tomas A, Pettersen JA, Andreazza AC, Black SE.

Neurobiol Aging. 2017 Nov;59:91-97. doi: 10.1016/j.neurobiolaging.2017.06.029. Epub 2017 Jul 11.


Antihypertensive Treatment is associated with MRI-Derived Markers of Neurodegeneration and Impaired Cognition: A Propensity-Weighted Cohort Study.

Edwards JD, Ramirez J, Callahan BL, Tobe SW, Oh P, Berezuk C, Lanctôt K, Swardfager W, Nestor S, Kiss A, Strother S, Black SE; Alzheimer’s Disease Neuroimaging Initiative.

J Alzheimers Dis. 2017;59(3):1113-1122. doi: 10.3233/JAD-170238.


Finding the Optimal volume and intensity of Resistance Training Exercise for Type 2 Diabetes: The FORTE Study, a Randomized Trial.

Yang P, Swardfager W, Fernandes D, Laredo S, Tomlinson G, Oh PI, Thomas S.

Diabetes Res Clin Pract. 2017 Aug;130:98-107. doi: 10.1016/j.diabres.2017.05.019. Epub 2017 May 19.


The effect of acute exercise on blood concentrations of brain-derived neurotrophic factor in healthy adults: a meta-analysis.

Dinoff A, Herrmann N, Swardfager W, Lanctôt KL.

Eur J Neurosci. 2017 Jul;46(1):1635-1646. doi: 10.1111/ejn.13603. Epub 2017 Jun 19. Review.


Comparability of an ADHD Latent Trait Between Groups: Disentangling True Between-Group Differences From Measurement Problems.

Cogo-Moreira H, Lúcio PS, Swardfager W, Gadelha A, Mari JJ, Miguel EC, Rohde LA, Salum GA.

J Atten Disord. 2019 May;23(7):712-720. doi: 10.1177/1087054717707047. Epub 2017 May 6.


Subcortical hyperintensities in the cholinergic system are associated with improvements in executive function in older adults with coronary artery disease undergoing cardiac rehabilitation.

Santiago C, Herrmann N, Swardfager W, Saleem M, Oh PI, Black SE, Bradley J, Lanctôt KL.

Int J Geriatr Psychiatry. 2018 Feb;33(2):279-287. doi: 10.1002/gps.4729. Epub 2017 May 5.


Plasma Phosphatidylethanolamine and Triacylglycerol Fatty Acid Concentrations are Altered in Major Depressive Disorder Patients with Seasonal Pattern.

Otoki Y, Hennebelle M, Levitt AJ, Nakagawa K, Swardfager W, Taha AY.

Lipids. 2017 Jun;52(6):559-571. doi: 10.1007/s11745-017-4254-1. Epub 2017 Apr 24.


Peripheral inflammatory markers indicate microstructural damage within periventricular white matter hyperintensities in Alzheimer's disease: A preliminary report.

Swardfager W, Yu D, Ramirez J, Cogo-Moreira H, Szilagyi G, Holmes MF, Scott CJ, Scola G, Chan PC, Chen J, Chan P, Sahlas DJ, Herrmann N, Lanctôt KL, Andreazza AC, Pettersen JA, Black SE.

Alzheimers Dement (Amst). 2017 Jan 21;7:56-60. doi: 10.1016/j.dadm.2016.12.011. eCollection 2017.


Altered soluble epoxide hydrolase-derived oxylipins in patients with seasonal major depression: An exploratory study.

Hennebelle M, Otoki Y, Yang J, Hammock BD, Levitt AJ, Taha AY, Swardfager W.

Psychiatry Res. 2017 Jun;252:94-101. doi: 10.1016/j.psychres.2017.02.056. Epub 2017 Feb 27.


Assessing Music Perception in Young Children: Evidence for and Psychometric Features of the M-Factor.

Barros CG, Swardfager W, Moreno S, Bortz G, Ilari B, Jackowski AP, Ploubidis G, Little TD, Lamont A, Cogo-Moreira H.

Front Neurosci. 2017 Jan 24;11:18. doi: 10.3389/fnins.2017.00018. eCollection 2017.


Role of Proinflammatory Cytokines in Dopaminergic System Disturbances, Implications for Anhedonic Features of MDD.

Pan Z, Rosenblat JD, Swardfager W, McIntyre RS.

Curr Pharm Des. 2017;23(14):2065-2072. doi: 10.2174/1381612823666170111144340. Review.


Validity of the Center for Epidemiological Studies Depression scale in Type 2 diabetes.

Carter J, Cogo-Moreira H, Herrmann N, Merino D, Yang P, Shah BR, Kiss A, Reitav J, Oh PI, Swardfager W.

J Psychosom Res. 2016 Nov;90:91-97. doi: 10.1016/j.jpsychores.2016.09.013. Epub 2016 Oct 1.


Poor stimulus discriminability as a common neuropsychological deficit between ADHD and reading ability in young children: a moderated mediation model.

Lúcio PS, Salum GA, Rohde LA, Swardfager W, Gadelha A, Vandekerckhove J, Pan PM, Polanczyk GV, do Rosário MC, Jackowski AP, Mari JJ, Cogo-Moreira H.

Psychol Med. 2017 Jan;47(2):255-266. doi: 10.1017/S0033291716002531. Epub 2016 Oct 4.


The Effect of Exercise Training on Resting Concentrations of Peripheral Brain-Derived Neurotrophic Factor (BDNF): A Meta-Analysis.

Dinoff A, Herrmann N, Swardfager W, Liu CS, Sherman C, Chan S, Lanctôt KL.

PLoS One. 2016 Sep 22;11(9):e0163037. doi: 10.1371/journal.pone.0163037. eCollection 2016.


Development and evaluation of a liquid chromatography-mass spectrometry method for rapid, accurate quantitation of malondialdehyde in human plasma.

Sobsey CA, Han J, Lin K, Swardfager W, Levitt A, Borchers CH.

J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Sep 1;1029-1030:205-212. doi: 10.1016/j.jchromb.2016.07.013. Epub 2016 Jul 7.


Depression, Type 2 Diabetes, and Poststroke Cognitive Impairment.

Swardfager W, MacIntosh BJ.

Neurorehabil Neural Repair. 2017 Jan;31(1):48-55. Epub 2016 Jun 29.


Mood and metabolism: Anhedonia as a clinical target in Type 2 diabetes.

Carter J, Swardfager W.

Psychoneuroendocrinology. 2016 Jul;69:123-32. doi: 10.1016/j.psyneuen.2016.04.002. Epub 2016 Apr 7. Review.


Coronary Artery Calcification: A Canary in the Cognitive Coalmine.

Swardfager W, Black SE.

J Am Coll Cardiol. 2016 Mar 8;67(9):1023-6. doi: 10.1016/j.jacc.2016.01.007. No abstract available.


Mapping inflammation onto mood: Inflammatory mediators of anhedonia.

Swardfager W, Rosenblat JD, Benlamri M, McIntyre RS.

Neurosci Biobehav Rev. 2016 May;64:148-66. doi: 10.1016/j.neubiorev.2016.02.017. Epub 2016 Feb 23. Review.


Inflammatory Markers in Mild Cognitive Impairment: A Meta-Analysis.

Saleem M, Herrmann N, Swardfager W, Eisen R, Lanctôt KL.

J Alzheimers Dis. 2015;47(3):669-79. doi: 10.3233/JAD-150042.


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