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Items: 1 to 50 of 77

1.

Phosphorylation of the HCN channel auxiliary subunit TRIP8b is altered in an animal model of temporal lobe epilepsy and modulates channel function.

Foote KM, Lyman KA, Han Y, Michailidis IE, Heuermann RJ, Mandikian D, Trimmer JS, Swanson GT, Chetkovich DM.

J Biol Chem. 2019 Oct 25;294(43):15743-15758. doi: 10.1074/jbc.RA119.010027. Epub 2019 Sep 5.

PMID:
31492750
2.

Peripherally derived T regulatory and γδ T cells have opposing roles in the pathogenesis of intractable pediatric epilepsy.

Xu D, Robinson AP, Ishii T, Duncan DS, Alden TD, Goings GE, Ifergan I, Podojil JR, Penaloza-MacMaster P, Kearney JA, Swanson GT, Miller SD, Koh S.

J Exp Med. 2018 Apr 2;215(4):1169-1186. doi: 10.1084/jem.20171285. Epub 2018 Feb 27.

3.

Excitatory Synaptic Input to Hilar Mossy Cells under Basal and Hyperexcitable Conditions.

Hedrick TP, Nobis WP, Foote KM, Ishii T, Chetkovich DM, Swanson GT.

eNeuro. 2017 Dec 4;4(6). pii: ENEURO.0364-17.2017. doi: 10.1523/ENEURO.0364-17.2017. eCollection 2017 Nov-Dec.

4.

Cadherin-10 Maintains Excitatory/Inhibitory Ratio through Interactions with Synaptic Proteins.

Smith KR, Jones KA, Kopeikina KJ, Burette AC, Copits BA, Yoon S, Forrest MP, Fawcett-Patel JM, Hanley JG, Weinberg RJ, Swanson GT, Penzes P.

J Neurosci. 2017 Nov 15;37(46):11127-11139. doi: 10.1523/JNEUROSCI.1153-17.2017. Epub 2017 Oct 13.

5.

Selective and regulated trapping of nicotinic receptor weak base ligands and relevance to smoking cessation.

Govind AP, Vallejo YF, Stolz JR, Yan JZ, Swanson GT, Green WN.

Elife. 2017 Jul 18;6. pii: e25651. doi: 10.7554/eLife.25651.

6.

N-glycan content modulates kainate receptor functional properties.

Vernon CG, Copits BA, Stolz JR, Guzmán YF, Swanson GT.

J Physiol. 2017 Sep 1;595(17):5913-5930. doi: 10.1113/JP274790. Epub 2017 Aug 2.

7.

Neto2 Assembles with Kainate Receptors in DRG Neurons during Development and Modulates Neurite Outgrowth in Adult Sensory Neurons.

Vernon CG, Swanson GT.

J Neurosci. 2017 Mar 22;37(12):3352-3363. doi: 10.1523/JNEUROSCI.2978-16.2017. Epub 2017 Feb 24.

8.

Complete Disruption of the Kainate Receptor Gene Family Results in Corticostriatal Dysfunction in Mice.

Xu J, Marshall JJ, Fernandes HB, Nomura T, Copits BA, Procissi D, Mori S, Wang L, Zhu Y, Swanson GT, Contractor A.

Cell Rep. 2017 Feb 21;18(8):1848-1857. doi: 10.1016/j.celrep.2017.01.073.

9.

A gain-of-function mutation in the GRIK2 gene causes neurodevelopmental deficits.

Guzmán YF, Ramsey K, Stolz JR, Craig DW, Huentelman MJ, Narayanan V, Swanson GT.

Neurol Genet. 2017 Jan 31;3(1):e129. doi: 10.1212/NXG.0000000000000129. eCollection 2017 Feb.

10.

Transduction of group I mGluR-mediated synaptic plasticity by β-arrestin2 signalling.

Eng AG, Kelver DA, Hedrick TP, Swanson GT.

Nat Commun. 2016 Nov 25;7:13571. doi: 10.1038/ncomms13571.

11.

Identification of critical functional determinants of kainate receptor modulation by auxiliary protein Neto2.

Griffith TN, Swanson GT.

J Physiol. 2015 Nov 15;593(22):4815-33. doi: 10.1113/JP271103. Epub 2015 Sep 20.

12.

Stephen F. Heinemann (1939–2014).

Elgoyhen AB, Swanson GT, Mulle C.

Neuron. 2014 Oct 1;84(1):15-7. No abstract available.

13.

Psychiatric risk factor ANK3/ankyrin-G nanodomains regulate the structure and function of glutamatergic synapses.

Smith KR, Kopeikina KJ, Fawcett-Patel JM, Leaderbrand K, Gao R, Schürmann B, Myczek K, Radulovic J, Swanson GT, Penzes P.

Neuron. 2014 Oct 22;84(2):399-415. doi: 10.1016/j.neuron.2014.10.010. Epub 2014 Oct 22.

14.

Modulation of ionotropic glutamate receptor function by vertebrate galectins.

Copits BA, Vernon CG, Sakai R, Swanson GT.

J Physiol. 2014 May 15;592(10):2079-96. doi: 10.1113/jphysiol.2013.269597. Epub 2014 Mar 10.

15.

Recent progress in neuroactive marine natural products.

Sakai R, Swanson GT.

Nat Prod Rep. 2014 Jan 17;31(2):273-309. doi: 10.1039/c3np70083f. Review.

16.

Studies on an (S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) receptor antagonist IKM-159: asymmetric synthesis, neuroactivity, and structural characterization.

Juknaitė L, Sugamata Y, Tokiwa K, Ishikawa Y, Takamizawa S, Eng A, Sakai R, Pickering DS, Frydenvang K, Swanson GT, Kastrup JS, Oikawa M.

J Med Chem. 2013 Mar 28;56(6):2283-93. doi: 10.1021/jm301590z. Epub 2013 Mar 13.

17.

Kainate receptor post-translational modifications differentially regulate association with 4.1N to control activity-dependent receptor endocytosis.

Copits BA, Swanson GT.

J Biol Chem. 2013 Mar 29;288(13):8952-65. doi: 10.1074/jbc.M112.440719. Epub 2013 Feb 11.

18.

Lateral thinking: CaMKII uncouples kainate receptors from mossy fibre synapses.

Copits BA, Swanson GT.

EMBO J. 2013 Feb 20;32(4):487-9. doi: 10.1038/emboj.2013.12. Epub 2013 Jan 29. No abstract available.

19.

A combined bioinformatics and chemoinformatics approach for developing asymmetric bivalent AMPA receptor positive allosteric modulators as neuroprotective agents.

Chen H, Wang CZ, Ding C, Wild C, Copits B, Swanson GT, Johnson KM, Zhou J.

ChemMedChem. 2013 Feb;8(2):226-30. doi: 10.1002/cmdc.201200554. Epub 2012 Dec 20.

20.

Isolation of novel prototype galectins from the marine ball sponge Cinachyrella sp. guided by their modulatory activity on mammalian glutamate-gated ion channels.

Ueda T, Nakamura Y, Smith CM, Copits BA, Inoue A, Ojima T, Matsunaga S, Swanson GT, Sakai R.

Glycobiology. 2013 Apr;23(4):412-25. doi: 10.1093/glycob/cws165. Epub 2012 Dec 4.

21.

Kainate receptor signaling in pain pathways.

Bhangoo SK, Swanson GT.

Mol Pharmacol. 2013 Feb;83(2):307-15. doi: 10.1124/mol.112.081398. Epub 2012 Oct 24. Review.

22.

Structure of a tetrameric galectin from Cinachyrella sp. (ball sponge).

Freymann DM, Nakamura Y, Focia PJ, Sakai R, Swanson GT.

Acta Crystallogr D Biol Crystallogr. 2012 Sep;68(Pt 9):1163-74. doi: 10.1107/S0907444912022834. Epub 2012 Aug 18.

23.

Afadin is required for maintenance of dendritic structure and excitatory tone.

Srivastava DP, Copits BA, Xie Z, Huda R, Jones KA, Mukherji S, Cahill ME, VanLeeuwen JE, Woolfrey KM, Rafalovich I, Swanson GT, Penzes P.

J Biol Chem. 2012 Oct 19;287(43):35964-74. doi: 10.1074/jbc.M112.363358. Epub 2012 Sep 4.

24.

Dancing partners at the synapse: auxiliary subunits that shape kainate receptor function.

Copits BA, Swanson GT.

Nat Rev Neurosci. 2012 Oct;13(10):675-86. Review.

25.

A novel form of low-frequency hippocampal mossy fiber plasticity induced by bimodal mGlu1 receptor signaling.

Frausto SF, Ito K, Marszalec W, Swanson GT.

J Neurosci. 2011 Nov 23;31(47):16897-906. doi: 10.1523/JNEUROSCI.1264-11.2011.

26.

Isolation, amino acid sequence and biological activities of novel long-chain polyamine-associated peptide toxins from the sponge Axinyssa aculeata.

Matsunaga S, Jimbo M, Gill MB, Wyhe LL, Murata M, Nonomura K, Swanson GT, Sakai R.

Chembiochem. 2011 Sep 19;12(14):2191-200. doi: 10.1002/cbic.201100329. Epub 2011 Aug 9.

27.

IQGAP1 regulates NR2A signaling, spine density, and cognitive processes.

Gao C, Frausto SF, Guedea AL, Tronson NC, Jovasevic V, Leaderbrand K, Corcoran KA, Guzmán YF, Swanson GT, Radulovic J.

J Neurosci. 2011 Jun 8;31(23):8533-42. doi: 10.1523/JNEUROSCI.1300-11.2011.

28.

Synaptic targeting and functional modulation of GluK1 kainate receptors by the auxiliary neuropilin and tolloid-like (NETO) proteins.

Copits BA, Robbins JS, Frausto S, Swanson GT.

J Neurosci. 2011 May 18;31(20):7334-40. doi: 10.1523/JNEUROSCI.0100-11.2011.

29.

Antinociceptive effects of MSVIII-19, a functional antagonist of the GluK1 kainate receptor.

Qiu CS, Lash-Van Wyhe L, Sasaki M, Sakai R, Swanson GT, Gereau RW 4th.

Pain. 2011 May;152(5):1052-60. doi: 10.1016/j.pain.2011.01.018. Epub 2011 Feb 15.

30.

Kainate receptors coming of age: milestones of two decades of research.

Contractor A, Mulle C, Swanson GT.

Trends Neurosci. 2011 Mar;34(3):154-63. doi: 10.1016/j.tins.2010.12.002. Epub 2011 Jan 20. Review.

31.

Novel N-methylated 8-oxoisoguanines from Pacific sponges with diverse neuroactivities.

Sakurada T, Gill MB, Frausto S, Copits B, Noguchi K, Shimamoto K, Swanson GT, Sakai R.

J Med Chem. 2010 Aug 26;53(16):6089-99. doi: 10.1021/jm100490m.

32.

A series of structurally novel heterotricyclic alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate receptor-selective antagonists.

Gill MB, Frausto S, Ikoma M, Sasaki M, Oikawa M, Sakai R, Swanson GT.

Br J Pharmacol. 2010 Jul;160(6):1417-29. doi: 10.1111/j.1476-5381.2010.00784.x.

33.

Regioselective Domino Metathesis of Unsymmetrical 7-Oxanorbornenes with Electron-Rich Vinyl Acetate toward Biologically Active Glutamate Analogues.

Oikawa M, Ikoma M, Sasaki M, Gill MB, Swanson GT, Shimamoto K, Sakai R.

European J Org Chem. 2009 Nov 1;2009(32):5531-5548.

34.

Improved synthesis and in vitro/in vivo activities of natural product-inspired, artificial glutamate analogs.

Oikawa M, Ikoma M, Sasaki M, Gill MB, Swanson GT, Shimamoto K, Sakai R.

Bioorg Med Chem. 2010 Jun 1;18(11):3795-804. doi: 10.1016/j.bmc.2010.04.044. Epub 2010 Apr 21.

35.

Pharmacological activity of C10-substituted analogs of the high-affinity kainate receptor agonist dysiherbaine.

Lash-Van Wyhe LL, Postila PA, Tsubone K, Sasaki M, Pentikäinen OT, Sakai R, Swanson GT.

Neuropharmacology. 2010 Mar;58(3):640-9. doi: 10.1016/j.neuropharm.2009.11.013. Epub 2009 Dec 4.

36.

Hippocampal NMDA receptor subunits differentially regulate fear memory formation and neuronal signal propagation.

Gao C, Gill MB, Tronson NC, Guedea AL, Guzmán YF, Huh KH, Corcoran KA, Swanson GT, Radulovic J.

Hippocampus. 2010 Sep;20(9):1072-82. doi: 10.1002/hipo.20705.

37.

High-affinity kainate receptor subunits are necessary for ionotropic but not metabotropic signaling.

Fernandes HB, Catches JS, Petralia RS, Copits BA, Xu J, Russell TA, Swanson GT, Contractor A.

Neuron. 2009 Sep 24;63(6):818-29. doi: 10.1016/j.neuron.2009.08.010.

38.

Exploring kainate receptor pharmacology using molecular dynamics simulations.

Postila PA, Swanson GT, Pentikäinen OT.

Neuropharmacology. 2010 Feb;58(2):515-27. doi: 10.1016/j.neuropharm.2009.08.019. Epub 2009 Sep 6.

39.

Regioselective Domino Metathesis of 7-Oxanorbornenes and Its Application to the Synthesis of Biologically Active Glutamate Analogues.

Ikoma M, Oikawa M, Gill MB, Swanson GT, Sakai R, Shimamoto K, Sasaki M.

European J Org Chem. 2008 Nov;2008(31):5215-5220.

40.

Glutamate binding and conformational flexibility of ligand-binding domains are critical early determinants of efficient kainate receptor biogenesis.

Gill MB, Vivithanaporn P, Swanson GT.

J Biol Chem. 2009 May 22;284(21):14503-12. doi: 10.1074/jbc.M900510200. Epub 2009 Apr 2.

41.

Full domain closure of the ligand-binding core of the ionotropic glutamate receptor iGluR5 induced by the high affinity agonist dysiherbaine and the functional antagonist 8,9-dideoxyneodysiherbaine.

Frydenvang K, Lash LL, Naur P, Postila PA, Pickering DS, Smith CM, Gajhede M, Sasaki M, Sakai R, Pentikaïnen OT, Swanson GT, Kastrup JS.

J Biol Chem. 2009 May 22;284(21):14219-29. doi: 10.1074/jbc.M808547200. Epub 2009 Mar 18.

42.

Ligands for ionotropic glutamate receptors.

Swanson GT, Sakai R.

Prog Mol Subcell Biol. 2009;46:123-57. doi: 10.1007/978-3-540-87895-7_5. Review.

43.

Targeting AMPA and kainate receptors in neurological disease: therapies on the horizon?

Swanson GT.

Neuropsychopharmacology. 2009 Jan;34(1):249-50. doi: 10.1038/npp.2008.158. Review. No abstract available.

44.

Rapid enhancement of two-step wiring plasticity by estrogen and NMDA receptor activity.

Srivastava DP, Woolfrey KM, Jones KA, Shum CY, Lash LL, Swanson GT, Penzes P.

Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14650-5. doi: 10.1073/pnas.0801581105. Epub 2008 Sep 18. Erratum in: Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):20045.. Woolfrey, Kevin [corrected to Woolfrey, Kevin M].

45.

Recording in the cerebellar slice.

Swanson GT, Contractor A.

Curr Protoc Neurosci. 2004 Feb;Chapter 6:Unit 6.18. doi: 10.1002/0471142301.ns0618s25.

PMID:
18428602
46.

Novel analogs and stereoisomers of the marine toxin neodysiherbaine with specificity for kainate receptors.

Lash LL, Sanders JM, Akiyama N, Shoji M, Postila P, Pentikäinen OT, Sasaki M, Sakai R, Swanson GT.

J Pharmacol Exp Ther. 2008 Feb;324(2):484-96. Epub 2007 Nov 21.

47.

Critical roles for the M3-S2 transduction linker domain in kainate receptor assembly and postassembly trafficking.

Vivithanaporn P, Lash LL, Marszalec W, Swanson GT.

J Neurosci. 2007 Sep 26;27(39):10423-33.

48.

Total synthesis and biological evaluation of neodysiherbaine A and analogues.

Shoji M, Akiyama N, Tsubone K, Lash LL, Sanders JM, Swanson GT, Sakai R, Shimamoto K, Oikawa M, Sasaki M.

J Org Chem. 2006 Jul 7;71(14):5208-20.

PMID:
16808508
49.
50.

Determination of binding site residues responsible for the subunit selectivity of novel marine-derived compounds on kainate receptors.

Sanders JM, Pentikäinen OT, Settimo L, Pentikäinen U, Shoji M, Sasaki M, Sakai R, Johnson MS, Swanson GT.

Mol Pharmacol. 2006 Jun;69(6):1849-60. Epub 2006 Mar 14.

PMID:
16537793

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