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Items: 46


Attenuation of oxidative stress-induced lesions in skeletal muscle in a mouse model of obesity-independent hyperlipidaemia and atherosclerosis through the inhibition of Nox2 activity.

Sfyri PP, Yuldasheva NY, Tzimou A, Giallourou N, Crispi V, Aburima A, Beltran-Alvarez P, Patel K, Mougios V, Swann JR, Kearney MT, Matsakas A.

Free Radic Biol Med. 2018 Dec;129:504-519. doi: 10.1016/j.freeradbiomed.2018.10.422. Epub 2018 Oct 17.


Para-cresol production by Clostridium difficile affects microbial diversity and membrane integrity of Gram-negative bacteria.

Passmore IJ, Letertre MPM, Preston MD, Bianconi I, Harrison MA, Nasher F, Kaur H, Hong HA, Baines SD, Cutting SM, Swann JR, Wren BW, Dawson LF.

PLoS Pathog. 2018 Sep 12;14(9):e1007191. doi: 10.1371/journal.ppat.1007191. eCollection 2018 Sep.


Inferring Metabolic Mechanisms of Interaction within a Defined Gut Microbiota.

Medlock GL, Carey MA, McDuffie DG, Mundy MB, Giallourou N, Swann JR, Kolling GL, Papin JA.

Cell Syst. 2018 Sep 26;7(3):245-257.e7. doi: 10.1016/j.cels.2018.08.003. Epub 2018 Sep 5.


Fecal microbiota and bile acid interactions with systemic and adipose tissue metabolism in diet-induced weight loss of obese postmenopausal women.

Alemán JO, Bokulich NA, Swann JR, Walker JM, De Rosa JC, Battaglia T, Costabile A, Pechlivanis A, Liang Y, Breslow JL, Blaser MJ, Holt PR.

J Transl Med. 2018 Sep 3;16(1):244. doi: 10.1186/s12967-018-1619-z.


Metabolic targets of watercress and PEITC in MCF-7 and MCF-10A cells explain differential sensitisation responses to ionising radiation.

Giallourou NS, Rowland IR, Rothwell SD, Packham G, Commane DM, Swann JR.

Eur J Nutr. 2018 Jul 31. doi: 10.1007/s00394-018-1789-8. [Epub ahead of print]


Early Life Interventions for Childhood Growth and Development in Tanzania (ELICIT): a protocol for a randomised factorial, double-blind, placebo-controlled trial of azithromycin, nitazoxanide and nicotinamide.

DeBoer MD, Platts-Mills JA, Scharf RJ, McDermid JM, Wanjuhi AW, Gratz J, Svensen E, Swann JR, Donowitz JR, Jatosh S, Houpt ER, Mduma E.

BMJ Open. 2018 Jul 7;8(7):e021817. doi: 10.1136/bmjopen-2018-021817.


In Vitro Modeling of Bile Acid Processing by the Human Fecal Microbiota.

Martin G, Kolida S, Marchesi JR, Want E, Sidaway JE, Swann JR.

Front Microbiol. 2018 Jun 5;9:1153. doi: 10.3389/fmicb.2018.01153. eCollection 2018.


A novel mouse model of Campylobacter jejuni enteropathy and diarrhea.

Giallourou N, Medlock GL, Bolick DT, Medeiros PH, Ledwaba SE, Kolling GL, Tung K, Guerry P, Swann JR, Guerrant RL.

PLoS Pathog. 2018 May 23;14(3):e1007083. doi: 10.1371/journal.ppat.1007083. eCollection 2018 Mar.


Metabolic phenotyping of malnutrition during the first 1000 days of life.

Mayneris-Perxachs J, Swann JR.

Eur J Nutr. 2018 Apr 11. doi: 10.1007/s00394-018-1679-0. [Epub ahead of print] Review.


Characterizing the metabolic phenotype of intestinal villus blunting in Zambian children with severe acute malnutrition and persistent diarrhea.

Farràs M, Chandwe K, Mayneris-Perxachs J, Amadi B, Louis-Auguste J, Besa E, Zyambo K, Guerrant R, Kelly P, Swann JR.

PLoS One. 2018 Mar 2;13(3):e0192092. doi: 10.1371/journal.pone.0192092. eCollection 2018. Erratum in: PLoS One. 2018 May 1;13(5):e0196934.


An in vivo assessment of the cholesterol-lowering efficacy of Lactobacillus plantarum ECGC 13110402 in normal to mildly hypercholesterolaemic adults.

Costabile A, Buttarazzi I, Kolida S, Quercia S, Baldini J, Swann JR, Brigidi P, Gibson GR.

PLoS One. 2017 Dec 11;12(12):e0187964. doi: 10.1371/journal.pone.0187964. eCollection 2017.


Cross-modulation of pathogen-specific pathways enhances malnutrition during enteric co-infection with Giardia lamblia and enteroaggregative Escherichia coli.

Bartelt LA, Bolick DT, Mayneris-Perxachs J, Kolling GL, Medlock GL, Zaenker EI, Donowitz J, Thomas-Beckett RV, Rogala A, Carroll IM, Singer SM, Papin J, Swann JR, Guerrant RL.

PLoS Pathog. 2017 Jul 27;13(7):e1006471. doi: 10.1371/journal.ppat.1006471. eCollection 2017 Jul.


Application of 1H NMR spectroscopy to the metabolic phenotyping of rodent brain extracts: A metabonomic study of gut microbial influence on host brain metabolism.

Swann JR, Garcia-Perez I, Braniste V, Wilson ID, Sidaway JE, Nicholson JK, Pettersson S, Holmes E.

J Pharm Biomed Anal. 2017 Sep 5;143:141-146. doi: 10.1016/j.jpba.2017.05.040. Epub 2017 May 31.


Increased Urinary Trimethylamine N-Oxide Following Cryptosporidium Infection and Protein Malnutrition Independent of Microbiome Effects.

Bolick DT, Mayneris-Perxachs J, Medlock GL, Kolling GL, Papin JA, Swann JR, Guerrant RL.

J Infect Dis. 2017 Jul 1;216(1):64-71. doi: 10.1093/infdis/jix234.


Association between urinary metabolic profile and the intestinal effects of cocoa in rats.

Massot-Cladera M, Mayneris-Perxachs J, Costabile A, Swann JR, Franch À, Pérez-Cano FJ, Castell M.

Br J Nutr. 2017 Mar;117(5):623-634. doi: 10.1017/S0007114517000496. Epub 2017 Mar 27.


Decoding Hidden Messages: Can Fecal Host Transcriptomics Open Pathways to Understanding Environmental Enteropathy?

Bartelt LA, Swann JR, Guerrant RL.

Cell Mol Gastroenterol Hepatol. 2016 Jan 28;2(2):114-115. doi: 10.1016/j.jcmgh.2016.01.002. eCollection 2016 Mar. No abstract available.


In vitro fermentation of B-GOS: impact on faecal bacterial populations and metabolic activity in autistic and non-autistic children.

Grimaldi R, Cela D, Swann JR, Vulevic J, Gibson GR, Tzortzis G, Costabile A.

FEMS Microbiol Ecol. 2017 Feb;93(2). pii: fiw233. Epub 2016 Nov 16.


Systems-level metabolism of the altered Schaedler flora, a complete gut microbiota.

Biggs MB, Medlock GL, Moutinho TJ, Lees HJ, Swann JR, Kolling GL, Papin JA.

ISME J. 2017 Feb;11(2):426-438. doi: 10.1038/ismej.2016.130. Epub 2016 Nov 8.


Protein- and zinc-deficient diets modulate the murine microbiome and metabolic phenotype.

Mayneris-Perxachs J, Bolick DT, Leng J, Medlock GL, Kolling GL, Papin JA, Swann JR, Guerrant RL.

Am J Clin Nutr. 2016 Nov;104(5):1253-1262. Epub 2016 Oct 12.


Enhanced exercise and regenerative capacity in a mouse model that violates size constraints of oxidative muscle fibres.

Omairi S, Matsakas A, Degens H, Kretz O, Hansson KA, Solbrå AV, Bruusgaard JC, Joch B, Sartori R, Giallourou N, Mitchell R, Collins-Hooper H, Foster K, Pasternack A, Ritvos O, Sandri M, Narkar V, Swann JR, Huber TB, Patel K.

Elife. 2016 Aug 5;5. pii: e16940. doi: 10.7554/eLife.16940.


Fermentation properties and potential prebiotic activity of Bimuno® galacto-oligosaccharide (65 % galacto-oligosaccharide content) on in vitro gut microbiota parameters.

Grimaldi R, Swann JR, Vulevic J, Gibson GR, Costabile A.

Br J Nutr. 2016 Aug;116(3):480-6. doi: 10.1017/S0007114516002269. Epub 2016 Jun 8.


Mycoprotein reduces energy intake and postprandial insulin release without altering glucagon-like peptide-1 and peptide tyrosine-tyrosine concentrations in healthy overweight and obese adults: a randomised-controlled trial.

Bottin JH, Swann JR, Cropp E, Chambers ES, Ford HE, Ghatei MA, Frost GS.

Br J Nutr. 2016 Jul;116(2):360-74. doi: 10.1017/S0007114516001872. Epub 2016 May 20.


Urinary N-methylnicotinamide and β-aminoisobutyric acid predict catch-up growth in undernourished Brazilian children.

Mayneris-Perxachs J, Lima AA, Guerrant RL, Leite ÁM, Moura AF, Lima NL, Soares AM, Havt A, Moore SR, Pinkerton R, Swann JR.

Sci Rep. 2016 Jan 27;6:19780. doi: 10.1038/srep19780.


L-rhamnose as a source of colonic propionate inhibits insulin secretion but does not influence measures of appetite or food intake.

Darzi J, Frost GS, Swann JR, Costabile A, Robertson MD.

Appetite. 2016 Mar 1;98:142-9. doi: 10.1016/j.appet.2015.12.011. Epub 2015 Dec 17.


Investigating mechanisms underpinning the detrimental impact of a high-fat diet in the developing and adult hypermuscular myostatin null mouse.

Matsakas A, Prosdocimo DA, Mitchell R, Collins-Hooper H, Giallourou N, Swann JR, Potter P, Epting T, Jain MK, Patel K.

Skelet Muscle. 2015 Dec 7;5:38. doi: 10.1186/s13395-015-0063-5. eCollection 2015.


Correction: Symmorphosis through Dietary Regulation: A Combinatorial Role for Proteolysis, Autophagy and Protein Synthesis in Normalising Muscle Metabolism and Function of Hypertrophic Mice after Acute Starvation.

Collins-Hooper H, Sartori R, Giallourou N, Matsakas A, Mitchell R, Makarenkova HP, Flasskamp H, Macharia R, Ray S, Swann JR, Sandri M, Patel K.

PLoS One. 2015 May 14;10(5):e0128731. doi: 10.1371/journal.pone.0128731. eCollection 2015. No abstract available.


Symmorphosis through dietary regulation: a combinatorial role for proteolysis, autophagy and protein synthesis in normalising muscle metabolism and function of hypertrophic mice after acute starvation.

Collins-Hooper H, Sartori R, Giallourou N, Matsakas A, Mitchell R, Makarenkova HP, Flasskamp H, Macharia R, Ray S, Swann JR, Sandri M, Patel K.

PLoS One. 2015 Mar 25;10(3):e0120524. doi: 10.1371/journal.pone.0120524. eCollection 2015. Erratum in: PLoS One. 2015;10(5):e0128731. Mararenkova, Helen [corrected to Makarenkova, Helen P].


Dominant components of the Thoroughbred metabolome characterised by (1) H-nuclear magnetic resonance spectroscopy: A metabolite atlas of common biofluids.

Escalona EE, Leng J, Dona AC, Merrifield CA, Holmes E, Proudman CJ, Swann JR.

Equine Vet J. 2015 Nov;47(6):721-30. doi: 10.1111/evj.12333. Epub 2015 Jan 28.


Impacts of plant-based foods in ancestral hominin diets on the metabolism and function of gut microbiota in vitro.

Frost GS, Walton GE, Swann JR, Psichas A, Costabile A, Johnson LP, Sponheimer M, Gibson GR, Barraclough TG.

MBio. 2014 May 20;5(3):e00853-14. doi: 10.1128/mBio.00853-14.


Nutrimetabonomics: nutritional applications of metabolic profiling.

Swann JR, Claus SP.

Sci Prog. 2014;97(Pt 1):41-7. Review.


The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism.

Frost G, Sleeth ML, Sahuri-Arisoylu M, Lizarbe B, Cerdan S, Brody L, Anastasovska J, Ghourab S, Hankir M, Zhang S, Carling D, Swann JR, Gibson G, Viardot A, Morrison D, Louise Thomas E, Bell JD.

Nat Commun. 2014 Apr 29;5:3611. doi: 10.1038/ncomms4611.


Harnessing microbiome and probiotic research in sub-Saharan Africa: recommendations from an African workshop.

Reid G, Nduti N, Sybesma W, Kort R, Kollmann TR, Adam R, Boga H, Brown EM, Einerhand A, El-Nezami H, Gloor GB, Kavere II, Lindahl J, Manges A, Mamo W, Martin R, McMillan A, Obiero J, Ochieng' PA, Onyango A, Rulisa S, Salminen E, Salminen S, Sije A, Swann JR, van Treuren W, Waweru D, Kemp SJ.

Microbiome. 2014 Apr 16;2:12. doi: 10.1186/2049-2618-2-12. eCollection 2014.


The impact of oligofructose on stimulation of gut hormones, appetite regulation and adiposity.

Daud NM, Ismail NA, Thomas EL, Fitzpatrick JA, Bell JD, Swann JR, Costabile A, Childs CE, Pedersen C, Goldstone AP, Frost GS.

Obesity (Silver Spring). 2014 Jun;22(6):1430-8. doi: 10.1002/oby.20754. Epub 2014 Apr 8.


Efficacy of increased resistant starch consumption in human type 2 diabetes.

Bodinham CL, Smith L, Thomas EL, Bell JD, Swann JR, Costabile A, Russell-Jones D, Umpleby AM, Robertson MD.

Endocr Connect. 2014 Apr 15;3(2):75-84. doi: 10.1530/EC-14-0036. Print 2014.


Probiotic administration attenuates myocardial hypertrophy and heart failure after myocardial infarction in the rat.

Gan XT, Ettinger G, Huang CX, Burton JP, Haist JV, Rajapurohitam V, Sidaway JE, Martin G, Gloor GB, Swann JR, Reid G, Karmazyn M.

Circ Heart Fail. 2014 May;7(3):491-9. doi: 10.1161/CIRCHEARTFAILURE.113.000978. Epub 2014 Mar 13.


Hydrophilic interaction chromatography-mass spectrometry for anionic metabolic profiling of urine from antibiotic-treated rats.

Kok MG, Swann JR, Wilson ID, Somsen GW, de Jong GJ.

J Pharm Biomed Anal. 2014 Apr;92:98-104. doi: 10.1016/j.jpba.2014.01.008. Epub 2014 Jan 20.


Microbial-mammalian cometabolites dominate the age-associated urinary metabolic phenotype in Taiwanese and American populations.

Swann JR, Spagou K, Lewis M, Nicholson JK, Glei DA, Seeman TE, Coe CL, Goldman N, Ryff CD, Weinstein M, Holmes E.

J Proteome Res. 2013 Jul 5;12(7):3166-80. doi: 10.1021/pr4000152. Epub 2013 Jun 24.


Hippurate: the natural history of a mammalian-microbial cometabolite.

Lees HJ, Swann JR, Wilson ID, Nicholson JK, Holmes E.

J Proteome Res. 2013 Apr 5;12(4):1527-46. doi: 10.1021/pr300900b. Epub 2013 Mar 6. Review.


Anionic metabolic profiling of urine from antibiotic-treated rats by capillary electrophoresis-mass spectrometry.

Kok MG, Ruijken MM, Swann JR, Wilson ID, Somsen GW, de Jong GJ.

Anal Bioanal Chem. 2013 Mar;405(8):2585-94. doi: 10.1007/s00216-012-6701-4. Epub 2013 Jan 12.


Nutrimetabonomics:applications for nutritional sciences, with specific reference to gut microbial interactions.

Claus SP, Swann JR.

Annu Rev Food Sci Technol. 2013;4:381-99. doi: 10.1146/annurev-food-030212-182612. Epub 2013 Jan 3. Review.


Differential effects of two fermentable carbohydrates on central appetite regulation and body composition.

Arora T, Loo RL, Anastasovska J, Gibson GR, Tuohy KM, Sharma RK, Swann JR, Deaville ER, Sleeth ML, Thomas EL, Holmes E, Bell JD, Frost G.

PLoS One. 2012;7(8):e43263. doi: 10.1371/journal.pone.0043263. Epub 2012 Aug 29.


Variation in antibiotic-induced microbial recolonization impacts on the host metabolic phenotypes of rats.

Swann JR, Tuohy KM, Lindfors P, Brown DT, Gibson GR, Wilson ID, Sidaway J, Nicholson JK, Holmes E.

J Proteome Res. 2011 Aug 5;10(8):3590-603. doi: 10.1021/pr200243t. Epub 2011 Jun 29.


Systemic gut microbial modulation of bile acid metabolism in host tissue compartments.

Swann JR, Want EJ, Geier FM, Spagou K, Wilson ID, Sidaway JE, Nicholson JK, Holmes E.

Proc Natl Acad Sci U S A. 2011 Mar 15;108 Suppl 1:4523-30. doi: 10.1073/pnas.1006734107. Epub 2010 Sep 13.


Integrated cytokine and metabolic analysis of pathological responses to parasite exposure in rodents.

Saric J, Li JV, Swann JR, Utzinger J, Calvert G, Nicholson JK, Dirnhofer S, Dallman MJ, Bictash M, Holmes E.

J Proteome Res. 2010 May 7;9(5):2255-64. doi: 10.1021/pr901019z.


Identification of metabolites in human hepatic bile using 800 MHz 1H NMR spectroscopy, HPLC-NMR/MS and UPLC-MS.

Duarte IF, Legido-Quigley C, Parker DA, Swann JR, Spraul M, Braumann U, Gil AM, Holmes E, Nicholson JK, Murphy GM, Vilca-Melendez H, Heaton N, Lindon JC.

Mol Biosyst. 2009 Feb;5(2):180-90. doi: 10.1039/b814426e. Epub 2008 Dec 15.


Comparison of two topical collagen-based hemostatic sponges during cardiothoracic procedures.

Zwischenberger JB, Brunston RL Jr, Swann JR, Conti VR.

J Invest Surg. 1999 Mar-Apr;12(2):101-6.


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