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Items: 1 to 50 of 55

1.

A comparison of collision cross section values obtained via travelling wave ion mobility-mass spectrometry and ultra high performance liquid chromatography-ion mobility-mass spectrometry: Application to the characterisation of metabolites in rat urine.

Nye LC, Williams JP, Munjoma NC, Letertre MPM, Coen M, Bouwmeester R, Martens L, Swann JR, Nicholson JK, Plumb RS, McCullagh M, Gethings LA, Lai S, Langridge JI, Vissers JPC, Wilson ID.

J Chromatogr A. 2019 Jun 27. pii: S0021-9673(19)30665-X. doi: 10.1016/j.chroma.2019.06.056. [Epub ahead of print]

PMID:
31285057
2.

Small intestinal microbial dysbiosis underlies symptoms associated with functional gastrointestinal disorders.

Saffouri GB, Shields-Cutler RR, Chen J, Yang Y, Lekatz HR, Hale VL, Cho JM, Battaglioli EJ, Bhattarai Y, Thompson KJ, Kalari KK, Behera G, Berry JC, Peters SA, Patel R, Schuetz AN, Faith JJ, Camilleri M, Sonnenburg JL, Farrugia G, Swann JR, Grover M, Knights D, Kashyap PC.

Nat Commun. 2019 May 1;10(1):2012. doi: 10.1038/s41467-019-09964-7.

3.

Chemotherapy-induced cachexia dysregulates hypothalamic and systemic lipoamines and is attenuated by cannabigerol.

Brierley DI, Harman JR, Giallourou N, Leishman E, Roashan AE, Mellows BAD, Bradshaw HB, Swann JR, Patel K, Whalley BJ, Williams CM.

J Cachexia Sarcopenia Muscle. 2019 Apr 29. doi: 10.1002/jcsm.12426. [Epub ahead of print]

4.

Obesity and Cage Environment Modulate Metabolism in the Zucker Rat: A Multiple Biological Matrix Approach to Characterizing Metabolic Phenomena.

Lees HJ, Swann JR, Poucher S, Holmes E, Wilson ID, Nicholson JK.

J Proteome Res. 2019 May 3;18(5):2160-2174. doi: 10.1021/acs.jproteome.9b00040. Epub 2019 Apr 18.

PMID:
30939873
5.

Ultrahigh-Performance Liquid Chromatography Tandem Mass Spectrometry with Electrospray Ionization Quantification of Tryptophan Metabolites and Markers of Gut Health in Serum and Plasma-Application to Clinical and Epidemiology Cohorts.

Whiley L, Nye LC, Grant I, Andreas N, Chappell KE, Sarafian MH, Misra R, Plumb RS, Lewis MR, Nicholson JK, Holmes E, Swann JR, Wilson ID.

Anal Chem. 2019 Apr 16;91(8):5207-5216. doi: 10.1021/acs.analchem.8b05884. Epub 2019 Mar 25.

6.

Antigen-presenting ILC3 regulate T cell-dependent IgA responses to colonic mucosal bacteria.

Melo-Gonzalez F, Kammoun H, Evren E, Dutton EE, Papadopoulou M, Bradford BM, Tanes C, Fardus-Reid F, Swann JR, Bittinger K, Mabbott NA, Vallance BA, Willinger T, Withers DR, Hepworth MR.

J Exp Med. 2019 Apr 1;216(4):728-742. doi: 10.1084/jem.20180871. Epub 2019 Feb 27.

7.

Health Outcomes, Pathogenesis and Epidemiology of Severe Acute Malnutrition (HOPE-SAM): rationale and methods of a longitudinal observational study.

Bwakura-Dangarembizi M, Amadi B, Bourke CD, Robertson RC, Mwapenya B, Chandwe K, Kapoma C, Chifunda K, Majo F, Ngosa D, Chakara P, Chulu N, Masimba F, Mapurisa I, Besa E, Mutasa K, Mwakamui S, Runodamoto T, Humphrey JH, Ntozini R, Wells JCK, Manges AR, Swann JR, Walker AS, Nathoo KJ, Kelly P, Prendergast AJ; HOPE-SAM study team.

BMJ Open. 2019 Feb 1;9(1):e023077. doi: 10.1136/bmjopen-2018-023077.

8.

Chronic sleep restriction in the rotenone Parkinson's disease model in rats reveals peripheral early-phase biomarkers.

Fagotti J, Targa ADS, Rodrigues LS, Noseda ACD, Dorieux FWC, Scarante FF, Ilkiw JL, Louzada FM, Chowdhury NR, van der Veen DR, Middleton B, Pennings JLA, Swann JR, Skene DJ, Lima MMS.

Sci Rep. 2019 Feb 13;9(1):1898. doi: 10.1038/s41598-018-37657-6.

9.

A murine model of diarrhea, growth impairment and metabolic disturbances with Shigella flexneri infection and the role of zinc deficiency.

Q S Medeiros PH, Ledwaba SE, Bolick DT, Giallourou N, Yum LK, Costa DVS, Oriá RB, Barry EM, Swann JR, Lima AÂM, Agaisse H, Guerrant RL.

Gut Microbes. 2019 Feb 3:1-16. doi: 10.1080/19490976.2018.1564430. [Epub ahead of print]

10.

Attenuation of oxidative stress-induced lesions in skeletal muscle in a mouse model of obesity-independent hyperlipidaemia and atherosclerosis through the inhibition of Nox2 activity.

Sfyri PP, Yuldasheva NY, Tzimou A, Giallourou N, Crispi V, Aburima A, Beltran-Alvarez P, Patel K, Mougios V, Swann JR, Kearney MT, Matsakas A.

Free Radic Biol Med. 2018 Dec;129:504-519. doi: 10.1016/j.freeradbiomed.2018.10.422. Epub 2018 Oct 17.

PMID:
30342191
11.

Para-cresol production by Clostridium difficile affects microbial diversity and membrane integrity of Gram-negative bacteria.

Passmore IJ, Letertre MPM, Preston MD, Bianconi I, Harrison MA, Nasher F, Kaur H, Hong HA, Baines SD, Cutting SM, Swann JR, Wren BW, Dawson LF.

PLoS Pathog. 2018 Sep 12;14(9):e1007191. doi: 10.1371/journal.ppat.1007191. eCollection 2018 Sep.

12.

Inferring Metabolic Mechanisms of Interaction within a Defined Gut Microbiota.

Medlock GL, Carey MA, McDuffie DG, Mundy MB, Giallourou N, Swann JR, Kolling GL, Papin JA.

Cell Syst. 2018 Sep 26;7(3):245-257.e7. doi: 10.1016/j.cels.2018.08.003. Epub 2018 Sep 5.

13.

Fecal microbiota and bile acid interactions with systemic and adipose tissue metabolism in diet-induced weight loss of obese postmenopausal women.

Alemán JO, Bokulich NA, Swann JR, Walker JM, De Rosa JC, Battaglia T, Costabile A, Pechlivanis A, Liang Y, Breslow JL, Blaser MJ, Holt PR.

J Transl Med. 2018 Sep 3;16(1):244. doi: 10.1186/s12967-018-1619-z.

14.

Metabolic targets of watercress and PEITC in MCF-7 and MCF-10A cells explain differential sensitisation responses to ionising radiation.

Giallourou NS, Rowland IR, Rothwell SD, Packham G, Commane DM, Swann JR.

Eur J Nutr. 2018 Jul 31. doi: 10.1007/s00394-018-1789-8. [Epub ahead of print]

15.

Early Life Interventions for Childhood Growth and Development in Tanzania (ELICIT): a protocol for a randomised factorial, double-blind, placebo-controlled trial of azithromycin, nitazoxanide and nicotinamide.

DeBoer MD, Platts-Mills JA, Scharf RJ, McDermid JM, Wanjuhi AW, Gratz J, Svensen E, Swann JR, Donowitz JR, Jatosh S, Houpt ER, Mduma E.

BMJ Open. 2018 Jul 7;8(7):e021817. doi: 10.1136/bmjopen-2018-021817.

16.

In Vitro Modeling of Bile Acid Processing by the Human Fecal Microbiota.

Martin G, Kolida S, Marchesi JR, Want E, Sidaway JE, Swann JR.

Front Microbiol. 2018 Jun 5;9:1153. doi: 10.3389/fmicb.2018.01153. eCollection 2018.

17.

A novel mouse model of Campylobacter jejuni enteropathy and diarrhea.

Giallourou N, Medlock GL, Bolick DT, Medeiros PH, Ledwaba SE, Kolling GL, Tung K, Guerry P, Swann JR, Guerrant RL.

PLoS Pathog. 2018 May 23;14(3):e1007083. doi: 10.1371/journal.ppat.1007083. eCollection 2018 Mar.

18.

Metabolic phenotyping of malnutrition during the first 1000 days of life.

Mayneris-Perxachs J, Swann JR.

Eur J Nutr. 2019 Apr;58(3):909-930. doi: 10.1007/s00394-018-1679-0. Epub 2018 Apr 11. Review.

19.

Characterizing the metabolic phenotype of intestinal villus blunting in Zambian children with severe acute malnutrition and persistent diarrhea.

Farràs M, Chandwe K, Mayneris-Perxachs J, Amadi B, Louis-Auguste J, Besa E, Zyambo K, Guerrant R, Kelly P, Swann JR.

PLoS One. 2018 Mar 2;13(3):e0192092. doi: 10.1371/journal.pone.0192092. eCollection 2018. Erratum in: PLoS One. 2018 May 1;13(5):e0196934.

20.

An in vivo assessment of the cholesterol-lowering efficacy of Lactobacillus plantarum ECGC 13110402 in normal to mildly hypercholesterolaemic adults.

Costabile A, Buttarazzi I, Kolida S, Quercia S, Baldini J, Swann JR, Brigidi P, Gibson GR.

PLoS One. 2017 Dec 11;12(12):e0187964. doi: 10.1371/journal.pone.0187964. eCollection 2017.

21.

Cross-modulation of pathogen-specific pathways enhances malnutrition during enteric co-infection with Giardia lamblia and enteroaggregative Escherichia coli.

Bartelt LA, Bolick DT, Mayneris-Perxachs J, Kolling GL, Medlock GL, Zaenker EI, Donowitz J, Thomas-Beckett RV, Rogala A, Carroll IM, Singer SM, Papin J, Swann JR, Guerrant RL.

PLoS Pathog. 2017 Jul 27;13(7):e1006471. doi: 10.1371/journal.ppat.1006471. eCollection 2017 Jul.

22.

Application of 1H NMR spectroscopy to the metabolic phenotyping of rodent brain extracts: A metabonomic study of gut microbial influence on host brain metabolism.

Swann JR, Garcia-Perez I, Braniste V, Wilson ID, Sidaway JE, Nicholson JK, Pettersson S, Holmes E.

J Pharm Biomed Anal. 2017 Sep 5;143:141-146. doi: 10.1016/j.jpba.2017.05.040. Epub 2017 May 31.

23.

Increased Urinary Trimethylamine N-Oxide Following Cryptosporidium Infection and Protein Malnutrition Independent of Microbiome Effects.

Bolick DT, Mayneris-Perxachs J, Medlock GL, Kolling GL, Papin JA, Swann JR, Guerrant RL.

J Infect Dis. 2017 Jul 1;216(1):64-71. doi: 10.1093/infdis/jix234. Erratum in: J Infect Dis. 2018 Apr 23;217(10):1673.

24.

Association between urinary metabolic profile and the intestinal effects of cocoa in rats.

Massot-Cladera M, Mayneris-Perxachs J, Costabile A, Swann JR, Franch À, Pérez-Cano FJ, Castell M.

Br J Nutr. 2017 Mar;117(5):623-634. doi: 10.1017/S0007114517000496. Epub 2017 Mar 27.

PMID:
28343458
25.

Decoding Hidden Messages: Can Fecal Host Transcriptomics Open Pathways to Understanding Environmental Enteropathy?

Bartelt LA, Swann JR, Guerrant RL.

Cell Mol Gastroenterol Hepatol. 2016 Jan 28;2(2):114-115. doi: 10.1016/j.jcmgh.2016.01.002. eCollection 2016 Mar. No abstract available.

26.

In vitro fermentation of B-GOS: impact on faecal bacterial populations and metabolic activity in autistic and non-autistic children.

Grimaldi R, Cela D, Swann JR, Vulevic J, Gibson GR, Tzortzis G, Costabile A.

FEMS Microbiol Ecol. 2017 Feb;93(2). pii: fiw233. Epub 2016 Nov 16.

27.

Systems-level metabolism of the altered Schaedler flora, a complete gut microbiota.

Biggs MB, Medlock GL, Moutinho TJ, Lees HJ, Swann JR, Kolling GL, Papin JA.

ISME J. 2017 Feb;11(2):426-438. doi: 10.1038/ismej.2016.130. Epub 2016 Nov 8.

28.

Protein- and zinc-deficient diets modulate the murine microbiome and metabolic phenotype.

Mayneris-Perxachs J, Bolick DT, Leng J, Medlock GL, Kolling GL, Papin JA, Swann JR, Guerrant RL.

Am J Clin Nutr. 2016 Nov;104(5):1253-1262. Epub 2016 Oct 12.

29.

Enhanced exercise and regenerative capacity in a mouse model that violates size constraints of oxidative muscle fibres.

Omairi S, Matsakas A, Degens H, Kretz O, Hansson KA, Solbrå AV, Bruusgaard JC, Joch B, Sartori R, Giallourou N, Mitchell R, Collins-Hooper H, Foster K, Pasternack A, Ritvos O, Sandri M, Narkar V, Swann JR, Huber TB, Patel K.

Elife. 2016 Aug 5;5. pii: e16940. doi: 10.7554/eLife.16940.

30.

Fermentation properties and potential prebiotic activity of Bimuno® galacto-oligosaccharide (65 % galacto-oligosaccharide content) on in vitro gut microbiota parameters.

Grimaldi R, Swann JR, Vulevic J, Gibson GR, Costabile A.

Br J Nutr. 2016 Aug;116(3):480-6. doi: 10.1017/S0007114516002269. Epub 2016 Jun 8.

31.

Mycoprotein reduces energy intake and postprandial insulin release without altering glucagon-like peptide-1 and peptide tyrosine-tyrosine concentrations in healthy overweight and obese adults: a randomised-controlled trial.

Bottin JH, Swann JR, Cropp E, Chambers ES, Ford HE, Ghatei MA, Frost GS.

Br J Nutr. 2016 Jul;116(2):360-74. doi: 10.1017/S0007114516001872. Epub 2016 May 20.

32.

Urinary N-methylnicotinamide and β-aminoisobutyric acid predict catch-up growth in undernourished Brazilian children.

Mayneris-Perxachs J, Lima AA, Guerrant RL, Leite ÁM, Moura AF, Lima NL, Soares AM, Havt A, Moore SR, Pinkerton R, Swann JR.

Sci Rep. 2016 Jan 27;6:19780. doi: 10.1038/srep19780.

33.

L-rhamnose as a source of colonic propionate inhibits insulin secretion but does not influence measures of appetite or food intake.

Darzi J, Frost GS, Swann JR, Costabile A, Robertson MD.

Appetite. 2016 Mar 1;98:142-9. doi: 10.1016/j.appet.2015.12.011. Epub 2015 Dec 17.

PMID:
26706043
34.

Investigating mechanisms underpinning the detrimental impact of a high-fat diet in the developing and adult hypermuscular myostatin null mouse.

Matsakas A, Prosdocimo DA, Mitchell R, Collins-Hooper H, Giallourou N, Swann JR, Potter P, Epting T, Jain MK, Patel K.

Skelet Muscle. 2015 Dec 7;5:38. doi: 10.1186/s13395-015-0063-5. eCollection 2015.

35.

Correction: Symmorphosis through Dietary Regulation: A Combinatorial Role for Proteolysis, Autophagy and Protein Synthesis in Normalising Muscle Metabolism and Function of Hypertrophic Mice after Acute Starvation.

Collins-Hooper H, Sartori R, Giallourou N, Matsakas A, Mitchell R, Makarenkova HP, Flasskamp H, Macharia R, Ray S, Swann JR, Sandri M, Patel K.

PLoS One. 2015 May 14;10(5):e0128731. doi: 10.1371/journal.pone.0128731. eCollection 2015. No abstract available.

36.

Symmorphosis through dietary regulation: a combinatorial role for proteolysis, autophagy and protein synthesis in normalising muscle metabolism and function of hypertrophic mice after acute starvation.

Collins-Hooper H, Sartori R, Giallourou N, Matsakas A, Mitchell R, Makarenkova HP, Flasskamp H, Macharia R, Ray S, Swann JR, Sandri M, Patel K.

PLoS One. 2015 Mar 25;10(3):e0120524. doi: 10.1371/journal.pone.0120524. eCollection 2015. Erratum in: PLoS One. 2015;10(5):e0128731. Mararenkova, Helen [corrected to Makarenkova, Helen P].

37.

Dominant components of the Thoroughbred metabolome characterised by (1) H-nuclear magnetic resonance spectroscopy: A metabolite atlas of common biofluids.

Escalona EE, Leng J, Dona AC, Merrifield CA, Holmes E, Proudman CJ, Swann JR.

Equine Vet J. 2015 Nov;47(6):721-30. doi: 10.1111/evj.12333. Epub 2015 Jan 28.

PMID:
25130591
38.

Impacts of plant-based foods in ancestral hominin diets on the metabolism and function of gut microbiota in vitro.

Frost GS, Walton GE, Swann JR, Psichas A, Costabile A, Johnson LP, Sponheimer M, Gibson GR, Barraclough TG.

MBio. 2014 May 20;5(3):e00853-14. doi: 10.1128/mBio.00853-14.

39.

Nutrimetabonomics: nutritional applications of metabolic profiling.

Swann JR, Claus SP.

Sci Prog. 2014;97(Pt 1):41-7. Review.

PMID:
24800468
40.

The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism.

Frost G, Sleeth ML, Sahuri-Arisoylu M, Lizarbe B, Cerdan S, Brody L, Anastasovska J, Ghourab S, Hankir M, Zhang S, Carling D, Swann JR, Gibson G, Viardot A, Morrison D, Louise Thomas E, Bell JD.

Nat Commun. 2014 Apr 29;5:3611. doi: 10.1038/ncomms4611.

41.

Harnessing microbiome and probiotic research in sub-Saharan Africa: recommendations from an African workshop.

Reid G, Nduti N, Sybesma W, Kort R, Kollmann TR, Adam R, Boga H, Brown EM, Einerhand A, El-Nezami H, Gloor GB, Kavere II, Lindahl J, Manges A, Mamo W, Martin R, McMillan A, Obiero J, Ochieng' PA, Onyango A, Rulisa S, Salminen E, Salminen S, Sije A, Swann JR, van Treuren W, Waweru D, Kemp SJ.

Microbiome. 2014 Apr 16;2:12. doi: 10.1186/2049-2618-2-12. eCollection 2014.

42.

The impact of oligofructose on stimulation of gut hormones, appetite regulation and adiposity.

Daud NM, Ismail NA, Thomas EL, Fitzpatrick JA, Bell JD, Swann JR, Costabile A, Childs CE, Pedersen C, Goldstone AP, Frost GS.

Obesity (Silver Spring). 2014 Jun;22(6):1430-8. doi: 10.1002/oby.20754. Epub 2014 Apr 8.

43.

Efficacy of increased resistant starch consumption in human type 2 diabetes.

Bodinham CL, Smith L, Thomas EL, Bell JD, Swann JR, Costabile A, Russell-Jones D, Umpleby AM, Robertson MD.

Endocr Connect. 2014 Apr 15;3(2):75-84. doi: 10.1530/EC-14-0036. Print 2014.

44.

Probiotic administration attenuates myocardial hypertrophy and heart failure after myocardial infarction in the rat.

Gan XT, Ettinger G, Huang CX, Burton JP, Haist JV, Rajapurohitam V, Sidaway JE, Martin G, Gloor GB, Swann JR, Reid G, Karmazyn M.

Circ Heart Fail. 2014 May;7(3):491-9. doi: 10.1161/CIRCHEARTFAILURE.113.000978. Epub 2014 Mar 13.

PMID:
24625365
45.

Hydrophilic interaction chromatography-mass spectrometry for anionic metabolic profiling of urine from antibiotic-treated rats.

Kok MG, Swann JR, Wilson ID, Somsen GW, de Jong GJ.

J Pharm Biomed Anal. 2014 Apr;92:98-104. doi: 10.1016/j.jpba.2014.01.008. Epub 2014 Jan 20.

PMID:
24503197
46.

Microbial-mammalian cometabolites dominate the age-associated urinary metabolic phenotype in Taiwanese and American populations.

Swann JR, Spagou K, Lewis M, Nicholson JK, Glei DA, Seeman TE, Coe CL, Goldman N, Ryff CD, Weinstein M, Holmes E.

J Proteome Res. 2013 Jul 5;12(7):3166-80. doi: 10.1021/pr4000152. Epub 2013 Jun 24.

47.

Hippurate: the natural history of a mammalian-microbial cometabolite.

Lees HJ, Swann JR, Wilson ID, Nicholson JK, Holmes E.

J Proteome Res. 2013 Apr 5;12(4):1527-46. doi: 10.1021/pr300900b. Epub 2013 Mar 6. Review.

PMID:
23342949
48.

Anionic metabolic profiling of urine from antibiotic-treated rats by capillary electrophoresis-mass spectrometry.

Kok MG, Ruijken MM, Swann JR, Wilson ID, Somsen GW, de Jong GJ.

Anal Bioanal Chem. 2013 Mar;405(8):2585-94. doi: 10.1007/s00216-012-6701-4. Epub 2013 Jan 12.

PMID:
23314487
49.

Nutrimetabonomics:applications for nutritional sciences, with specific reference to gut microbial interactions.

Claus SP, Swann JR.

Annu Rev Food Sci Technol. 2013;4:381-99. doi: 10.1146/annurev-food-030212-182612. Epub 2013 Jan 3. Review.

PMID:
23297777
50.

Differential effects of two fermentable carbohydrates on central appetite regulation and body composition.

Arora T, Loo RL, Anastasovska J, Gibson GR, Tuohy KM, Sharma RK, Swann JR, Deaville ER, Sleeth ML, Thomas EL, Holmes E, Bell JD, Frost G.

PLoS One. 2012;7(8):e43263. doi: 10.1371/journal.pone.0043263. Epub 2012 Aug 29.

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