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Items: 12


Microscale Adaptation of In Vitro Transcription/Translation for High-Throughput Screening of Natural Product Extract Libraries.

Lowell AN, Santoro N, Swaney SM, McQuade TJ, Schultz PJ, Larsen MJ, Sherman DH.

Chem Biol Drug Des. 2015 Dec;86(6):1331-8. doi: 10.1111/cbdd.12614. Epub 2015 Jul 25.


The site of action of oxazolidinone antibiotics in living bacteria and in human mitochondria.

Leach KL, Swaney SM, Colca JR, McDonald WG, Blinn JR, Thomasco LM, Gadwood RC, Shinabarger D, Xiong L, Mankin AS.

Mol Cell. 2007 May 11;26(3):393-402.


Oxazolidinones inhibit cellular proliferation via inhibition of mitochondrial protein synthesis.

Nagiec EE, Wu L, Swaney SM, Chosay JG, Ross DE, Brieland JK, Leach KL.

Antimicrob Agents Chemother. 2005 Sep;49(9):3896-902.


1H nuclear magnetic resonance study of oxazolidinone binding to bacterial ribosomes.

Zhou CC, Swaney SM, Shinabarger DL, Stockman BJ.

Antimicrob Agents Chemother. 2002 Mar;46(3):625-9.


The oxazolidinone linezolid inhibits initiation of protein synthesis in bacteria.

Swaney SM, Aoki H, Ganoza MC, Shinabarger DL.

Antimicrob Agents Chemother. 1998 Dec;42(12):3251-5.


Pyrimidine thioethers: a novel class of HIV-1 reverse transcriptase inhibitors with activity against BHAP-resistant HIV.

Nugent RA, Schlachter ST, Murphy MJ, Cleek GJ, Poel TJ, Wishka DG, Graber DR, Yagi Y, Keiser BJ, Olmsted RA, Kopta LA, Swaney SM, Poppe SM, Morris J, Tarpley WG, Thomas RC.

J Med Chem. 1998 Sep 24;41(20):3793-803.


(-)-6-Chloro-2-[(1-furo[2, 3-c]pyridin-5-ylethyl)thio]-4-pyrimidinamine, PNU-142721, a new broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitor.

Wishka DG, Graber DR, Kopta LA, Olmsted RA, Friis JM, Hosley JD, Adams WJ, Seest EP, Castle TM, Dolak LA, Keiser BJ, Yagi Y, Jeganathan A, Schlachter ST, Murphy MJ, Cleek GJ, Nugent RA, Poppe SM, Swaney SM, Han F, Watt W, White WL, Poel TJ, Thomas RC, Morris J, et al.

J Med Chem. 1998 Apr 23;41(9):1357-60. No abstract available.


Mechanism of action of oxazolidinones: effects of linezolid and eperezolid on translation reactions.

Shinabarger DL, Marotti KR, Murray RW, Lin AH, Melchior EP, Swaney SM, Dunyak DS, Demyan WF, Buysse JM.

Antimicrob Agents Chemother. 1997 Oct;41(10):2132-6.


A mutation in reverse transcriptase of bis(heteroaryl)piperazine-resistant human immunodeficiency virus type 1 that confers increased sensitivity to other nonnucleoside inhibitors.

Dueweke TJ, Pushkarskaya T, Poppe SM, Swaney SM, Zhao JQ, Chen IS, Stevenson M, Tarpley WG.

Proc Natl Acad Sci U S A. 1993 May 15;90(10):4713-7.


U-90152, a potent inhibitor of human immunodeficiency virus type 1 replication.

Dueweke TJ, Poppe SM, Romero DL, Swaney SM, So AG, Downey KM, Althaus IW, Reusser F, Busso M, Resnick L, et al.

Antimicrob Agents Chemother. 1993 May;37(5):1127-31.

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