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Current and emerging immunotherapeutic approaches to the treatment of multiple myeloma.

Swan D, Lynch K, Gurney M, O'Dwyer M.

Ther Adv Hematol. 2019 Jun 18;10:2040620719854171. doi: 10.1177/2040620719854171. eCollection 2019. Review.


The Genetics of Cholesteatoma Study. Loss-of-function variants in an affected family.

Prinsley P, Jennings BA, Bhutta M, Swan D, Willis G, Philpott C.

Clin Otolaryngol. 2019 May 17. doi: 10.1111/coa.13365. [Epub ahead of print]


Immunodeficiency, autoimmune thrombocytopenia and enterocolitis caused by autosomal recessive deficiency of PIK3CD-encoded phosphoinositide 3-kinase δ.

Swan DJ, Aschenbrenner D, Lamb CA, Chakraborty K, Clark J, Pandey S, Engelhardt KR, Chen R, Cavounidis A, Ding Y, Krasnogor N, Carey CD, Acres M, Needham S, Cant AJ, Arkwright PD, Chandra A, Okkenhaug K, Uhlig HH, Hambleton S.

Haematologica. 2019 May 9. pii: haematol.2018.208397. doi: 10.3324/haematol.2018.208397. [Epub ahead of print]


Projected effectiveness of HIV detection during early infection and rapid ART initiation among MSM and transgender women in Peru: A modeling study.

Dimitrov D, Wood D, Ulrich A, Swan DA, Adamson B, Lama JR, Sanchez J, Duerr A.

Infect Dis Model. 2019 Apr 6;4:73-82. doi: 10.1016/j.idm.2019.04.001. eCollection 2019.


The problem of under-diagnosis and over-diagnosis of pulmonary embolism.

Swan D, Hitchen S, Klok FA, Thachil J.

Thromb Res. 2019 May;177:122-129. doi: 10.1016/j.thromres.2019.03.012. Epub 2019 Mar 14. Review.


An essential role for the Zn2+ transporter ZIP7 in B cell development.

Anzilotti C, Swan DJ, Boisson B, Deobagkar-Lele M, Oliveira C, Chabosseau P, Engelhardt KR, Xu X, Chen R, Alvarez L, Berlinguer-Palmini R, Bull KR, Cawthorne E, Cribbs AP, Crockford TL, Dang TS, Fearn A, Fenech EJ, de Jong SJ, Lagerholm BC, Ma CS, Sims D, van den Berg B, Xu Y, Cant AJ, Kleiner G, Leahy TR, de la Morena MT, Puck JM, Shapiro RS, van der Burg M, Chapman JR, Christianson JC, Davies B, McGrath JA, Przyborski S, Santibanez Koref M, Tangye SG, Werner A, Rutter GA, Padilla-Parra S, Casanova JL, Cornall RJ, Conley ME, Hambleton S.

Nat Immunol. 2019 Mar;20(3):350-361. doi: 10.1038/s41590-018-0295-8. Epub 2019 Feb 4.


Coupled virus - bacteria interactions and ecosystem function in an engineered microbial system.

Brown MR, Baptista JC, Lunn M, Swan DL, Smith SJ, Davenport RJ, Allen BD, Sloan WT, Curtis TP.

Water Res. 2019 Apr 1;152:264-273. doi: 10.1016/j.watres.2019.01.003. Epub 2019 Jan 11.


Hepatitis C Prevalence and Management Among Patients Receiving Opioid Substitution Treatment in General Practice in Ireland: Baseline Data from a Feasibility Study.

Murtagh R, Swan D, O'Connor E, McCombe G, Lambert JS, Avramovic G, Cullen W.

Interact J Med Res. 2018 Dec 19;7(2):e10313. doi: 10.2196/10313.


Venous thromboembolism in multiple myeloma - choice of prophylaxis, role of direct oral anticoagulants and special considerations.

Swan D, Rocci A, Bradbury C, Thachil J.

Br J Haematol. 2018 Nov;183(4):538-556. doi: 10.1111/bjh.15684. Epub 2018 Nov 18. Review.


Signal transducer and activator of transcription 5B deficiency due to a novel missense mutation in the coiled-coil domain.

Acres MJ, Gothe F, Grainger A, Skelton AJ, Swan DJ, Willet JDP, Leech S, Galcheva S, Iotova V, Hambleton S, Engelhardt KR.

J Allergy Clin Immunol. 2019 Jan;143(1):413-416.e4. doi: 10.1016/j.jaci.2018.08.032. Epub 2018 Sep 8. No abstract available.


Herpes simplex virus-2 dynamics as a probe to measure the extremely rapid and spatially localized tissue-resident T-cell response.

Schiffer JT, Swan DA, Prlic M, Lund JM.

Immunol Rev. 2018 Sep;285(1):113-133. doi: 10.1111/imr.12672. Review.


A Fixed Spatial Structure of CD8+ T Cells in Tissue during Chronic HSV-2 Infection.

Schiffer JT, Swan DA, Roychoudhury P, Lund JM, Prlic M, Zhu J, Wald A, Corey L.

J Immunol. 2018 Sep 1;201(5):1522-1535. doi: 10.4049/jimmunol.1800471. Epub 2018 Jul 25.


Integrated Hepatitis C Care for People Who Inject Drugs (Heplink): Protocol for a Feasibility Study in Primary Care.

McCombe G, Swan D, O'Connor E, Avramovic G, Vickerman P, Ward Z, Surey J, Macías J, Lambert JS, Cullen W.

JMIR Res Protoc. 2018 Jun 4;7(6):e149. doi: 10.2196/resprot.9043.


A Gradual Effects Model for Single-Case Designs.

Swan DM, Pustejovsky JE.

Multivariate Behav Res. 2018 Jul-Aug;53(4):574-593. doi: 10.1080/00273171.2018.1466681. Epub 2018 May 14.


Identified mental disorders in older adults in primary care: A cross-sectional database study.

McCombe G, Fogarty F, Swan D, Hannigan A, Fealy GM, Kyne L, Meagher D, Cullen W.

Eur J Gen Pract. 2018 Dec;24(1):84-91. doi: 10.1080/13814788.2017.1402884.


Reintroduction of anticoagulant therapy after intracranial haemorrhage: If and when?

Scott M, Low R, Swan D, Thachil J.

Blood Rev. 2018 May;32(3):256-263. doi: 10.1016/j.blre.2017.12.002. Epub 2017 Dec 20. Review.


Hepcare Europe - bridging the gap in the treatment of hepatitis C: study protocol.

Swan D, Cullen W, Macias J, Oprea C, Story A, Surey J, Vickerman P, Lambert JS.

Expert Rev Gastroenterol Hepatol. 2018 Mar;12(3):303-314. doi: 10.1080/17474124.2018.1424541. Epub 2018 Jan 16.


Preventing blood-borne virus infection in people who inject drugs in the UK: systematic review, stakeholder interviews, psychosocial intervention development and feasibility randomised controlled trial.

Gilchrist G, Swan D, Shaw A, Keding A, Towers S, Craine N, Munro A, Hughes E, Parrott S, Mdege N, Strang J, Taylor A, Watson J.

Health Technol Assess. 2017 Nov;21(72):1-312. doi: 10.3310/hta21720.


Cutaneous Vasculitis: An Unusual Presentation of a Biclonal Nodal Plasma Cell Dyscrasia.

Swan D, Murphy M, Elhassadi E.

Case Rep Hematol. 2017;2017:8152610. doi: 10.1155/2017/8152610. Epub 2017 Sep 13.


Leaf LIMS: A Flexible Laboratory Information Management System with a Synthetic Biology Focus.

Craig T, Holland R, D'Amore R, Johnson JR, McCue HV, West A, Zulkower V, Tekotte H, Cai Y, Swan D, Davey RP, Hertz-Fowler C, Hall A, Caddick M.

ACS Synth Biol. 2017 Dec 15;6(12):2273-2280. doi: 10.1021/acssynbio.7b00212. Epub 2017 Sep 13.


Early-onset autoimmune disease due to a heterozygous loss-of-function mutation in TNFAIP3 (A20).

Duncan CJA, Dinnigan E, Theobald R, Grainger A, Skelton AJ, Hussain R, Willet JDP, Swan DJ, Coxhead J, Thomas MF, Thomas J, Zamvar V, Slatter MA, Cant AJ, Engelhardt KR, Hambleton S.

Ann Rheum Dis. 2018 May;77(5):783-786. doi: 10.1136/annrheumdis-2016-210944. Epub 2017 Jun 28. No abstract available.


Transient Oral Human Cytomegalovirus Infections Indicate Inefficient Viral Spread from Very Few Initially Infected Cells.

Mayer BT, Krantz EM, Swan D, Ferrenberg J, Simmons K, Selke S, Huang ML, Casper C, Corey L, Wald A, Schiffer JT, Gantt S.

J Virol. 2017 May 26;91(12). pii: e00380-17. doi: 10.1128/JVI.00380-17. Print 2017 Jun 15.


A Systematic Review and Meta-analysis of Psychosocial Interventions to Reduce Drug and Sexual Blood Borne Virus Risk Behaviours Among People Who Inject Drugs.

Gilchrist G, Swan D, Widyaratna K, Marquez-Arrico JE, Hughes E, Mdege ND, Martyn-St James M, Tirado-Munoz J.

AIDS Behav. 2017 Jul;21(7):1791-1811. doi: 10.1007/s10461-017-1755-0. Review.


The acceptability and feasibility of a brief psychosocial intervention to reduce blood-borne virus risk behaviours among people who inject drugs: a randomised control feasibility trial of a psychosocial intervention (the PROTECT study) versus treatment as usual.

Gilchrist G, Swan D, Shaw A, Keding A, Towers S, Craine N, Munro A, Hughes E, Parrott S, Strang J, Taylor A, Watson J.

Harm Reduct J. 2017 Mar 21;14(1):14. doi: 10.1186/s12954-017-0142-5.


Improving and correcting the contiguity of long-read genome assemblies of three plant species using optical mapping and chromosome conformation capture data.

Jiao WB, Accinelli GG, Hartwig B, Kiefer C, Baker D, Severing E, Willing EM, Piednoel M, Woetzel S, Madrid-Herrero E, Huettel B, Hümann U, Reinhard R, Koch MA, Swan D, Clavijo B, Coupland G, Schneeberger K.

Genome Res. 2017 May;27(5):778-786. doi: 10.1101/gr.213652.116. Epub 2017 Feb 3.


Development and implementation of a 'Mental Health Finder' software tool within an electronic medical record system.

Swan D, Hannigan A, Higgins S, McDonnell R, Meagher D, Cullen W.

Ir J Med Sci. 2017 Feb;186(1):191-200. doi: 10.1007/s11845-016-1541-4. Epub 2017 Jan 3.


Treatment of moderate-to-severe atopic eczema in adults within the U.K.: results of a national survey of dermatologists.

Taylor K, Swan DJ, Affleck A, Flohr C, Reynolds NJ; U.K. Translational Research Network in Dermatology and the U.K. Dermatology Clinical Trials Network.

Br J Dermatol. 2017 Jun;176(6):1617-1623. doi: 10.1111/bjd.15235. Epub 2017 Apr 16.


Mutations in Three Genes Encoding Proteins Involved in Hair Shaft Formation Cause Uncombable Hair Syndrome.

Ü Basmanav FB, Cau L, Tafazzoli A, Méchin MC, Wolf S, Romano MT, Valentin F, Wiegmann H, Huchenq A, Kandil R, Garcia Bartels N, Kilic A, George S, Ralser DJ, Bergner S, Ferguson DJP, Oprisoreanu AM, Wehner M, Thiele H, Altmüller J, Nürnberg P, Swan D, Houniet D, Büchner A, Weibel L, Wagner N, Grimalt R, Bygum A, Serre G, Blume-Peytavi U, Sprecher E, Schoch S, Oji V, Hamm H, Farrant P, Simon M, Betz RC.

Am J Hum Genet. 2016 Dec 1;99(6):1292-1304. doi: 10.1016/j.ajhg.2016.10.004. Epub 2016 Nov 17.


Feasibility of alcohol screening among patients receiving opioid treatment in primary care.

Henihan AM, McCombe G, Klimas J, Swan D, Leahy D, Anderson R, Bury G, Dunne CP, Keenan E, Lambert JS, Meagher D, O'Gorman C, O'Toole TP, Saunders J, Shorter GW, Smyth BP, Kaner E, Cullen W.

BMC Fam Pract. 2016 Nov 5;17(1):153.


Identification of Heterozygous Single- and Multi-exon Deletions in IL7R by Whole Exome Sequencing.

Engelhardt KR, Xu Y, Grainger A, Germani Batacchi MG, Swan DJ, Willet JD, Abd Hamid IJ, Agyeman P, Barge D, Bibi S, Jenkins L, Flood TJ, Abinun M, Slatter MA, Gennery AR, Cant AJ, Santibanez Koref M, Gilmour K, Hambleton S.

J Clin Immunol. 2017 Jan;37(1):42-50. doi: 10.1007/s10875-016-0343-9. Epub 2016 Nov 2.


Tolerogenic dendritic cells generated with dexamethasone and vitamin D3 regulate rheumatoid arthritis CD4+ T cells partly via transforming growth factor-β1.

Anderson AE, Swan DJ, Wong OY, Buck M, Eltherington O, Harry RA, Patterson AM, Pratt AG, Reynolds G, Doran JP, Kirby JA, Isaacs JD, Hilkens CM.

Clin Exp Immunol. 2017 Jan;187(1):113-123. doi: 10.1111/cei.12870. Epub 2016 Nov 2.


Emergence of wheat blast in Bangladesh was caused by a South American lineage of Magnaporthe oryzae.

Islam MT, Croll D, Gladieux P, Soanes DM, Persoons A, Bhattacharjee P, Hossain MS, Gupta DR, Rahman MM, Mahboob MG, Cook N, Salam MU, Surovy MZ, Sancho VB, Maciel JL, NhaniJúnior A, Castroagudín VL, Reges JT, Ceresini PC, Ravel S, Kellner R, Fournier E, Tharreau D, Lebrun MH, McDonald BA, Stitt T, Swan D, Talbot NJ, Saunders DG, Win J, Kamoun S.

BMC Biol. 2016 Oct 3;14(1):84.


A germline mutation of CDKN2A and a novel RPLP1-C19MC fusion detected in a rare melanotic neuroectodermal tumor of infancy: a case report.

Barnes DJ, Hookway E, Athanasou N, Kashima T, Oppermann U, Hughes S, Swan D, Lueerssen D, Anson J, Hassan AB.

BMC Cancer. 2016 Aug 12;16:629. doi: 10.1186/s12885-016-2669-3.


Mathematical Modeling Predicts that Increased HSV-2 Shedding in HIV-1 Infected Persons Is Due to Poor Immunologic Control in Ganglia and Genital Mucosa.

Schiffer JT, Swan DA, Magaret A, Schacker TW, Wald A, Corey L.

PLoS One. 2016 Jun 10;11(6):e0155124. doi: 10.1371/journal.pone.0155124. eCollection 2016.


Mathematical modeling of herpes simplex virus-2 suppression with pritelivir predicts trial outcomes.

Schiffer JT, Swan DA, Magaret A, Corey L, Wald A, Ossig J, Ruebsamen-Schaeff H, Stoelben S, Timmler B, Zimmermann H, Melhem MR, Van Wart SA, Rubino CM, Birkmann A.

Sci Transl Med. 2016 Feb 3;8(324):324ra15. doi: 10.1126/scitranslmed.aad6654.


Four Methods for Analyzing Partial Interval Recording Data, with Application to Single-Case Research.

Pustejovsky JE, Swan DM.

Multivariate Behav Res. 2015;50(3):365-80. doi: 10.1080/00273171.2015.1014879.


PEX6 is Expressed in Photoreceptor Cilia and Mutated in Deafblindness with Enamel Dysplasia and Microcephaly.

Zaki MS, Heller R, Thoenes M, Nürnberg G, Stern-Schneider G, Nürnberg P, Karnati S, Swan D, Fateen E, Nagel-Wolfrum K, Mostafa MI, Thiele H, Wolfrum U, Baumgart-Vogt E, Bolz HJ.

Hum Mutat. 2016 Feb;37(2):170-4. doi: 10.1002/humu.22934. Epub 2015 Dec 14.


Crowdsourced direct-to-consumer genomic analysis of a family quartet.

Corpas M, Valdivia-Granda W, Torres N, Greshake B, Coletta A, Knaus A, Harrison AP, Cariaso M, Moran F, Nielsen F, Swan D, Weiss Solís DY, Krawitz P, Schacherer F, Schols P, Yang H, Borry P, Glusman G, Robinson PN.

BMC Genomics. 2015 Nov 7;16:910. doi: 10.1186/s12864-015-1973-7.


Digital network of writers helps to foster spirit of collaboration.

Klimas J, Swan D, McCombe G, Henihan AM.

Nurs Stand. 2015 Jul 29;29(48):30-1. doi: 10.7748/ns.29.48.30.s38. No abstract available.


Monogamy, the Protective Fallacy: Sexual versus Emotional Exclusivity and the Implication for Sexual Health Risk.

Swan DJ, Thompson SC.

J Sex Res. 2016;53(1):64-73. doi: 10.1080/00224499.2014.1003771. Epub 2015 Jul 13.


Psychosocial Interventions for Problem Alcohol Use in Primary Care Settings (PINTA): Baseline Feasibility Data.

Klimas J, Marie Henihan A, McCombe G, Swan D, Anderson R, Bury G, Dunne C, Keenan E, Saunders J, Shorter GW, Smyth BP, Cullen W.

J Dual Diagn. 2015;11(2):97-106. doi: 10.1080/15504263.2015.1027630.


Development and evaluation of an educational intervention in youth mental health for primary care practitioners.

Birrane J, Swan D, Aherne D, Davis R, Hannigan A, McPhillips D, Meagher D, O'Regan A, Ryan P, Schaffalitzky E, Cullen W.

Ir J Psychol Med. 2015 Mar;32(1):137-146. doi: 10.1017/ipm.2014.71.


How social context impacts on the development, identification and treatment of mental and substance use disorders among young people - a qualitative study of health care workers.

Leahy D, Schaffalitzky E, Armstrong C, Latham L, McNicholas F, Meagher D, Nathan Y, O'Connor R, O'Keane V, Ryan P, Smyth BP, Swan D, Cullen W.

Ir J Psychol Med. 2015 Mar;32(1):117-128. doi: 10.1017/ipm.2014.70.


Screening for atrial fibrillation in general practice: a national, cross-sectional study of an innovative technology.

Bury G, Swan D, Cullen W, Keane D, Tobin H, Egan M, Fitzmaurice D, Carberry C, Kelleher C.

Int J Cardiol. 2015 Jan 15;178:247-52. doi: 10.1016/j.ijcard.2014.10.037. Epub 2014 Nov 9.


Early-onset lymphoproliferation and autoimmunity caused by germline STAT3 gain-of-function mutations.

Milner JD, Vogel TP, Forbes L, Ma CA, Stray-Pedersen A, Niemela JE, Lyons JJ, Engelhardt KR, Zhang Y, Topcagic N, Roberson ED, Matthews H, Verbsky JW, Dasu T, Vargas-Hernandez A, Varghese N, McClain KL, Karam LB, Nahmod K, Makedonas G, Mace EM, Sorte HS, Perminow G, Rao VK, O'Connell MP, Price S, Su HC, Butrick M, McElwee J, Hughes JD, Willet J, Swan D, Xu Y, Santibanez-Koref M, Slowik V, Dinwiddie DL, Ciaccio CE, Saunders CJ, Septer S, Kingsmore SF, White AJ, Cant AJ, Hambleton S, Cooper MA.

Blood. 2015 Jan 22;125(4):591-9. doi: 10.1182/blood-2014-09-602763. Epub 2014 Oct 30.


Agreement between amoA gene-specific quantitative PCR and fluorescence in situ hybridization in the measurement of ammonia-oxidizing bacteria in activated sludge.

Baptista JD, Lunn M, Davenport RJ, Swan DL, Read LF, Brown MR, Morais C, Curtis TP.

Appl Environ Microbiol. 2014 Oct;80(19):5901-10. doi: 10.1128/AEM.01383-14. Epub 2014 Jul 7.


Herpes simplex virus-2 transmission probability estimates based on quantity of viral shedding.

Schiffer JT, Mayer BT, Fong Y, Swan DA, Wald A.

J R Soc Interface. 2014 Mar 26;11(95):20140160. doi: 10.1098/rsif.2014.0160. Print 2014 Jun 6.


The supposed tumor suppressor gene WWOX is mutated in an early lethal microcephaly syndrome with epilepsy, growth retardation and retinal degeneration.

Abdel-Salam G, Thoenes M, Afifi HH, Körber F, Swan D, Bolz HJ.

Orphanet J Rare Dis. 2014 Jan 23;9:12. doi: 10.1186/1750-1172-9-12.


Rapid viral expansion and short drug half-life explain the incomplete effectiveness of current herpes simplex virus 2-directed antiviral agents.

Schiffer JT, Swan DA, Corey L, Wald A.

Antimicrob Agents Chemother. 2013 Dec;57(12):5820-9. doi: 10.1128/AAC.01114-13. Epub 2013 Sep 9.


Youth understanding of healthy eating and obesity: a focus group study.

Sylvetsky AC, Hennink M, Comeau D, Welsh JA, Hardy T, Matzigkeit L, Swan DW, Walsh SM, Vos MB.

J Obes. 2013;2013:670295. doi: 10.1155/2013/670295. Epub 2013 Jul 17.

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