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Items: 1 to 50 of 61

1.

N1-methyl-pseudouridine in mRNA enhances translation through eIF2α-dependent and independent mechanisms by increasing ribosome density.

Svitkin YV, Cheng YM, Chakraborty T, Presnyak V, John M, Sonenberg N.

Nucleic Acids Res. 2017 Jun 2;45(10):6023-6036. doi: 10.1093/nar/gkx135.

2.

DAP5 associates with eIF2β and eIF4AI to promote Internal Ribosome Entry Site driven translation.

Liberman N, Gandin V, Svitkin YV, David M, Virgili G, Jaramillo M, Holcik M, Nagar B, Kimchi A, Sonenberg N.

Nucleic Acids Res. 2015 Apr 20;43(7):3764-75. doi: 10.1093/nar/gkv205. Epub 2015 Mar 16.

3.

Control of translation and miRNA-dependent repression by a novel poly(A) binding protein, hnRNP-Q.

Svitkin YV, Yanagiya A, Karetnikov AE, Alain T, Fabian MR, Khoutorsky A, Perreault S, Topisirovic I, Sonenberg N.

PLoS Biol. 2013;11(5):e1001564. doi: 10.1371/journal.pbio.1001564. Epub 2013 May 21.

4.

Translational homeostasis via the mRNA cap-binding protein, eIF4E.

Yanagiya A, Suyama E, Adachi H, Svitkin YV, Aza-Blanc P, Imataka H, Mikami S, Martineau Y, Ronai ZA, Sonenberg N.

Mol Cell. 2012 Jun 29;46(6):847-58. doi: 10.1016/j.molcel.2012.04.004. Epub 2012 May 10.

5.

Translational control of the activation of transcription factor NF-κB and production of type I interferon by phosphorylation of the translation factor eIF4E.

Herdy B, Jaramillo M, Svitkin YV, Rosenfeld AB, Kobayashi M, Walsh D, Alain T, Sean P, Robichaud N, Topisirovic I, Furic L, Dowling RJO, Sylvestre A, Rong L, Colina R, Costa-Mattioli M, Fritz JH, Olivier M, Brown E, Mohr I, Sonenberg N.

Nat Immunol. 2012 Apr 29;13(6):543-550. doi: 10.1038/ni.2291.

6.

Cap and cap-binding proteins in the control of gene expression.

Topisirovic I, Svitkin YV, Sonenberg N, Shatkin AJ.

Wiley Interdiscip Rev RNA. 2011 Mar-Apr;2(2):277-98. doi: 10.1002/wrna.52. Epub 2010 Oct 28. Review.

PMID:
21957010
7.

An efficient system for let-7 microRNA and GW182 protein-mediated deadenylation in vitro.

Fabian MR, Svitkin YV, Sonenberg N.

Methods Mol Biol. 2011;725:207-17. doi: 10.1007/978-1-61779-046-1_14.

PMID:
21528456
8.

The poly(A)-binding protein partner Paip2a controls translation during late spermiogenesis in mice.

Yanagiya A, Delbes G, Svitkin YV, Robaire B, Sonenberg N.

J Clin Invest. 2010 Sep;120(9):3389-400. doi: 10.1172/JCI43350. Epub 2010 Aug 25.

9.

DCB-3503, a tylophorine analog, inhibits protein synthesis through a novel mechanism.

Wang Y, Gao W, Svitkin YV, Chen AP, Cheng YC.

PLoS One. 2010 Jul 15;5(7):e11607. doi: 10.1371/journal.pone.0011607.

10.

The helicase protein DHX29 promotes translation initiation, cell proliferation, and tumorigenesis.

Parsyan A, Shahbazian D, Martineau Y, Petroulakis E, Alain T, Larsson O, Mathonnet G, Tettweiler G, Hellen CU, Pestova TV, Svitkin YV, Sonenberg N.

Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22217-22. doi: 10.1073/pnas.0909773106. Epub 2009 Dec 11.

11.

Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation.

Fabian MR, Mathonnet G, Sundermeier T, Mathys H, Zipprich JT, Svitkin YV, Rivas F, Jinek M, Wohlschlegel J, Doudna JA, Chen CY, Shyu AB, Yates JR 3rd, Hannon GJ, Filipowicz W, Duchaine TF, Sonenberg N.

Mol Cell. 2009 Sep 24;35(6):868-80. doi: 10.1016/j.molcel.2009.08.004. Epub 2009 Aug 27.

12.

Requirement of RNA binding of mammalian eukaryotic translation initiation factor 4GI (eIF4GI) for efficient interaction of eIF4E with the mRNA cap.

Yanagiya A, Svitkin YV, Shibata S, Mikami S, Imataka H, Sonenberg N.

Mol Cell Biol. 2009 Mar;29(6):1661-9. doi: 10.1128/MCB.01187-08. Epub 2008 Dec 29.

13.

General RNA-binding proteins have a function in poly(A)-binding protein-dependent translation.

Svitkin YV, Evdokimova VM, Brasey A, Pestova TV, Fantus D, Yanagiya A, Imataka H, Skabkin MA, Ovchinnikov LP, Merrick WC, Sonenberg N.

EMBO J. 2009 Jan 7;28(1):58-68. doi: 10.1038/emboj.2008.259. Epub 2008 Dec 11.

14.

Translational control of the innate immune response through IRF-7.

Colina R, Costa-Mattioli M, Dowling RJ, Jaramillo M, Tai LH, Breitbach CJ, Martineau Y, Larsson O, Rong L, Svitkin YV, Makrigiannis AP, Bell JC, Sonenberg N.

Nature. 2008 Mar 20;452(7185):323-8. doi: 10.1038/nature06730. Epub 2008 Feb 13.

PMID:
18272964
15.

Stimulation of picornavirus replication by the poly(A) tail in a cell-free extract is largely independent of the poly(A) binding protein (PABP).

Svitkin YV, Costa-Mattioli M, Herdy B, Perreault S, Sonenberg N.

RNA. 2007 Dec;13(12):2330-40. Epub 2007 Oct 17.

16.
17.

MicroRNA inhibition of translation initiation in vitro by targeting the cap-binding complex eIF4F.

Mathonnet G, Fabian MR, Svitkin YV, Parsyan A, Huck L, Murata T, Biffo S, Merrick WC, Darzynkiewicz E, Pillai RS, Filipowicz W, Duchaine TF, Sonenberg N.

Science. 2007 Sep 21;317(5845):1764-7. Epub 2007 Jul 26.

18.

[Translational control by the poly(A) binding protein: a check for mRNA integrity].

Svitkin YV, Sonenberg N.

Mol Biol (Mosk). 2006 Jul-Aug;40(4):684-93. Review. Russian.

PMID:
16913227
19.

A mechanism of translational repression by competition of Paip2 with eIF4G for poly(A) binding protein (PABP) binding.

Karim MM, Svitkin YV, Kahvejian A, De Crescenzo G, Costa-Mattioli M, Sonenberg N.

Proc Natl Acad Sci U S A. 2006 Jun 20;103(25):9494-9. Epub 2006 Jun 13.

20.

Eukaryotic translation initiation factor 4E availability controls the switch between cap-dependent and internal ribosomal entry site-mediated translation.

Svitkin YV, Herdy B, Costa-Mattioli M, Gingras AC, Raught B, Sonenberg N.

Mol Cell Biol. 2005 Dec;25(23):10556-65.

21.
22.

Mammalian poly(A)-binding protein is a eukaryotic translation initiation factor, which acts via multiple mechanisms.

Kahvejian A, Svitkin YV, Sukarieh R, M'Boutchou MN, Sonenberg N.

Genes Dev. 2005 Jan 1;19(1):104-13.

23.
24.

An efficient system for cap- and poly(A)-dependent translation in vitro.

Svitkin YV, Sonenberg N.

Methods Mol Biol. 2004;257:155-70.

PMID:
14770004
25.

Cell-free synthesis of encephalomyocarditis virus.

Svitkin YV, Sonenberg N.

J Virol. 2003 Jun;77(11):6551-5.

26.

Human rhinovirus 2A proteinase cleavage sites in eukaryotic initiation factors (eIF) 4GI and eIF4GII are different.

Gradi A, Svitkin YV, Sommergruber W, Imataka H, Morino S, Skern T, Sonenberg N.

J Virol. 2003 Apr;77(8):5026-9.

27.

RNA aptamers to initiation factor 4A helicase hinder cap-dependent translation by blocking ATP hydrolysis.

Oguro A, Ohtsu T, Svitkin YV, Sonenberg N, Nakamura Y.

RNA. 2003 Apr;9(4):394-407.

28.

Poly(A)-binding protein interaction with elF4G stimulates picornavirus IRES-dependent translation.

Svitkin YV, Imataka H, Khaleghpour K, Kahvejian A, Liebig HD, Sonenberg N.

RNA. 2001 Dec;7(12):1743-52.

29.

Dual interactions of the translational repressor Paip2 with poly(A) binding protein.

Khaleghpour K, Kahvejian A, De Crescenzo G, Roy G, Svitkin YV, Imataka H, O'Connor-McCourt M, Sonenberg N.

Mol Cell Biol. 2001 Aug;21(15):5200-13.

30.

The requirement for eukaryotic initiation factor 4A (elF4A) in translation is in direct proportion to the degree of mRNA 5' secondary structure.

Svitkin YV, Pause A, Haghighat A, Pyronnet S, Witherell G, Belsham GJ, Sonenberg N.

RNA. 2001 Mar;7(3):382-94.

31.

Translational repression by a novel partner of human poly(A) binding protein, Paip2.

Khaleghpour K, Svitkin YV, Craig AW, DeMaria CT, Deo RC, Burley SK, Sonenberg N.

Mol Cell. 2001 Jan;7(1):205-16.

34.
35.

Rapamycin and wortmannin enhance replication of a defective encephalomyocarditis virus.

Svitkin YV, Hahn H, Gingras AC, Palmenberg AC, Sonenberg N.

J Virol. 1998 Jul;72(7):5811-9.

36.

A novel functional human eukaryotic translation initiation factor 4G.

Gradi A, Imataka H, Svitkin YV, Rom E, Raught B, Morino S, Sonenberg N.

Mol Cell Biol. 1998 Jan;18(1):334-42.

37.

The La autoantigen contains a dimerization domain that is essential for enhancing translation.

Craig AW, Svitkin YV, Lee HS, Belsham GJ, Sonenberg N.

Mol Cell Biol. 1997 Jan;17(1):163-9.

38.

General RNA binding proteins render translation cap dependent.

Svitkin YV, Ovchinnikov LP, Dreyfuss G, Sonenberg N.

EMBO J. 1996 Dec 16;15(24):7147-55. Erratum in: EMBO J 1997 Feb 17;16(4):896.

39.
40.

Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation.

Beretta L, Gingras AC, Svitkin YV, Hall MN, Sonenberg N.

EMBO J. 1996 Feb 1;15(3):658-64.

41.

The role of the La autoantigen in internal initiation.

Belsham GJ, Sonenberg N, Svitkin YV.

Curr Top Microbiol Immunol. 1995;203:85-98. Review. No abstract available.

PMID:
7555092
43.

Internal translation initiation on poliovirus RNA: further characterization of La function in poliovirus translation in vitro.

Svitkin YV, Meerovitch K, Lee HS, Dholakia JN, Kenan DJ, Agol VI, Sonenberg N.

J Virol. 1994 Mar;68(3):1544-50.

44.

La autoantigen enhances and corrects aberrant translation of poliovirus RNA in reticulocyte lysate.

Meerovitch K, Svitkin YV, Lee HS, Lejbkowicz F, Kenan DJ, Chan EK, Agol VI, Keene JD, Sonenberg N.

J Virol. 1993 Jul;67(7):3798-807.

45.

Towards development of an in vitro translation test for poliovirus neurovirulence.

Svitkin YV, Alpatova GA, Lipskaya GA, Maslova SV, Agol VI, Kew O, Meerovitch K, Sonenberg N.

Dev Biol Stand. 1993;78:27-32.

PMID:
8388829
46.

Prokaryotic-like cis elements in the cap-independent internal initiation of translation on picornavirus RNA.

Pilipenko EV, Gmyl AP, Maslova SV, Svitkin YV, Sinyakov AN, Agol VI.

Cell. 1992 Jan 10;68(1):119-31.

PMID:
1310072
47.

Coupled mutations in the 5'-untranslated region of the Sabin poliovirus strains during in vivo passages: structural and functional implications.

Muzychenko AR, Lipskaya GYu, Maslova SV, Svitkin YV, Pilipenko EV, Nottay BK, Kew OM, Agol VI.

Virus Res. 1991 Oct;21(2):111-22.

PMID:
1661980
48.

Use of protamine sulphate for elimination of substrate DNA in poliovaccines produced on continuous cell lines.

Amosenko FA, Svitkin YV, Popova VD, Terletskaya EN, Timofeev AV, Elbert LB, Lashkevich VA, Drozdov SG.

Vaccine. 1991 Mar;9(3):207-9.

PMID:
1645900
49.

Translation deficiency of the Sabin type 3 poliovirus genome: association with an attenuating mutation C472----U.

Svitkin YV, Cammack N, Minor PD, Almond JW.

Virology. 1990 Mar;175(1):103-9.

PMID:
2155504
50.

Inactivated vaccine against tick-borne encephalitis (TBE) derived from heteroploid continuous monkey cell line.

Elbert LB, Terletskay EN, Timofeev AV, Mironova LL, Khapchaev UK, Amosenko FA, Svitkin YV, Alpatova GA, Krutyanskaya GL.

Vaccine. 1989 Oct;7(5):477. No abstract available.

PMID:
2815981

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