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Items: 1 to 50 of 95

1.

Beating tissue factor at its own game: Design and properties of a soluble tissue factor-independent coagulation factor VIIa.

Sorensen AB, Tuneew I, Svensson LA, Persson E, Østergaard H, Overgaard MT, Olsen OH, Gandhi PS.

J Biol Chem. 2019 Dec 4. pii: jbc.RA119.009183. doi: 10.1074/jbc.RA119.009183. [Epub ahead of print]

2.

Crystal structures of the Bacillus subtilis prophage lytic cassette proteins XepA and YomS.

Freitag-Pohl S, Jasilionis A, Håkansson M, Svensson LA, Kovačič R, Welin M, Watzlawick H, Wang L, Altenbuchner J, Płotka M, Kaczorowska AK, Kaczorowski T, Nordberg Karlsson E, Al-Karadaghi S, Walse B, Aevarsson A, Pohl E.

Acta Crystallogr D Struct Biol. 2019 Nov 1;75(Pt 11):1028-1039. doi: 10.1107/S2059798319013330. Epub 2019 Nov 1.

3.

Molecular Basis of Enhanced Activity in Factor VIIa-Trypsin Variants Conveys Insights into Tissue Factor-mediated Allosteric Regulation of Factor VIIa Activity.

Sorensen AB, Madsen JJ, Svensson LA, Pedersen AA, Østergaard H, Overgaard MT, Olsen OH, Gandhi PS.

J Biol Chem. 2016 Feb 26;291(9):4671-83. doi: 10.1074/jbc.M115.698613. Epub 2015 Dec 22.

4.

Patients with lymphatic malformations who receive the immunostimulant OK-432 experience excellent long-term outcomes.

Ghaffarpour N, Petrini B, Svensson LA, Boman K, Wester T, Claesson G.

Acta Paediatr. 2015 Nov;104(11):1169-73. doi: 10.1111/apa.13086. Epub 2015 Jul 14.

PMID:
26081020
5.

Evaluation of the metal binding sites in a recombinant coagulation factor VIII identifies two sites with unique metal binding properties.

Svensson LA, Thim L, Olsen OH, Nicolaisen EM.

Biol Chem. 2013 Jun;394(6):761-5. doi: 10.1515/hsz-2012-0298.

PMID:
23435097
6.

Is the subcallosal medial prefrontal cortex a common site of atrophy in Alzheimer's disease and frontotemporal lobar degeneration?

Lindberg O, Westman E, Karlsson S, Ostberg P, Svensson LA, Simmons A, Wahlund LO.

Front Aging Neurosci. 2012 Nov 23;4:32. doi: 10.3389/fnagi.2012.00032. eCollection 2012.

7.

Hemostatic effect of a monoclonal antibody mAb 2021 blocking the interaction between FXa and TFPI in a rabbit hemophilia model.

Hilden I, Lauritzen B, Sørensen BB, Clausen JT, Jespersgaard C, Krogh BO, Bowler AN, Breinholt J, Gruhler A, Svensson LA, Petersen HH, Petersen LC, Balling KW, Hansen L, Hermit MB, Egebjerg T, Friederichsen B, Ezban M, Bjørn SE.

Blood. 2012 Jun 14;119(24):5871-8. doi: 10.1182/blood-2012-01-401620. Epub 2012 May 4.

PMID:
22563084
8.

Frontotemporal dementia as a frontostriatal disorder: neostriatal morphology as a biomarker and structural basis for an endophenotype.

Looi JC, Walterfang M, Velakoulis D, Macfarlane MD, Svensson LA, Wahlund LO.

Aust N Z J Psychiatry. 2012 May;46(5):422-34. doi: 10.1177/0004867411432076. Epub 2012 Jan 5. Review.

PMID:
22535292
9.

Shape analysis of the neostriatum in subtypes of frontotemporal lobar degeneration: neuroanatomically significant regional morphologic change.

Looi JC, Walterfang M, Styner M, Niethammer M, Svensson LA, Lindberg O, Ostberg P, Botes L, Orndahl E, Chua P, Velakoulis D, Wahlund LO.

Psychiatry Res. 2011 Feb 28;191(2):98-111. doi: 10.1016/j.pscychresns.2010.09.014. Epub 2011 Jan 15.

PMID:
21237621
10.

Shinella fusca sp. nov., isolated from domestic waste compost.

Vaz-Moreira I, Faria C, Lopes AR, Svensson LA, Moore ER, Nunes OC, Manaia CM.

Int J Syst Evol Microbiol. 2010 Jan;60(Pt 1):144-8. doi: 10.1099/ijs.0.009498-0. Epub 2009 Jul 31.

PMID:
19648331
11.

[Eye and visual problems common in adoptees from Eastern Europe].

Grönlund MA, Aring E, Strömland K, Landgren M, Svensson LA, Hellström A.

Lakartidningen. 2009 Mar 4-10;106(10):676-8. Swedish. No abstract available.

PMID:
19418686
12.

Mechanism of the Ca2+-induced enhancement of the intrinsic factor VIIa activity.

Bjelke JR, Olsen OH, Fodje M, Svensson LA, Bang S, Bolt G, Kragelund BB, Persson E.

J Biol Chem. 2008 Sep 19;283(38):25863-70. doi: 10.1074/jbc.M800841200. Epub 2008 Jul 17.

13.

Crystal structure of a prolactin receptor antagonist bound to the extracellular domain of the prolactin receptor.

Svensson LA, Bondensgaard K, Nørskov-Lauritsen L, Christensen L, Becker P, Andersen MD, Maltesen MJ, Rand KD, Breinholt J.

J Biol Chem. 2008 Jul 4;283(27):19085-94. doi: 10.1074/jbc.M801202200. Epub 2008 May 8.

14.

A novel study of association between Neisseria gonorrhoeae and the human carbohydrate blood groups.

Perry HE, Franklin RA, Bray SJ, Lo MK, Svensson LA, Henry SM.

Immunohematology. 2007;23(3):100-4.

PMID:
18284299
15.

The crystallography beamline I711 at MAX II.

Cerenius Y, Ståhl K, Svensson LA, Ursby T, Oskarsson A, Albertsson J, Liljas A.

J Synchrotron Radiat. 2000 Jul 1;7(Pt 4):203-8. Epub 2000 Jul 1.

PMID:
16609196
16.

Induction of apoptosis/necrosis in various human cell lineages by Haemophilus ducreyi cytolethal distending toxin.

Wising C, Azem J, Zetterberg M, Svensson LA, Ahlman K, Lagergård T.

Toxicon. 2005 May;45(6):767-76.

PMID:
15804526
17.

Structure-activity relationships of dimeric PPAR agonists.

Sauerberg P, Mogensen JP, Jeppesen L, Svensson LA, Fleckner J, Nehlin J, Wulff EM, Pettersson I.

Bioorg Med Chem Lett. 2005 Mar 1;15(5):1497-500.

PMID:
15713415
18.

Large dimeric ligands with favorable pharmacokinetic properties and peroxisome proliferator-activated receptor agonist activity in vitro and in vivo.

Sauerberg P, Bury PS, Mogensen JP, Deussen HJ, Pettersson I, Fleckner J, Nehlin J, Frederiksen KS, Albrektsen T, Din N, Svensson LA, Ynddal L, Wulff EM, Jeppesen L.

J Med Chem. 2003 Nov 6;46(23):4883-94.

PMID:
14584939
19.

Etiology of genital ulcer disease and association with human immunodeficiency virus infection in two tanzanian cities.

Ahmed HJ, Mbwana J, Gunnarsson E, Ahlman K, Guerino C, Svensson LA, Mhalu F, Lagergard T.

Sex Transm Dis. 2003 Feb;30(2):114-9.

PMID:
12567167
20.

Design and synthesis of novel PPARalpha/gamma/delta triple activators using a known PPARalpha/gamma dual activator as structural template.

Mogensen JP, Jeppesen L, Bury PS, Pettersson I, Fleckner J, Nehlin J, Frederiksen KS, Albrektsen T, Din N, Mortensen SB, Svensson LA, Wassermann K, Wulff EM, Ynddal L, Sauerberg P.

Bioorg Med Chem Lett. 2003 Jan 20;13(2):257-60.

PMID:
12482434
21.

Toxicity and immunogenicity of purified Haemophilus ducreyi cytolethal distending toxin in a rabbit model.

Wising C, Svensson LA, Ahmed HJ, Sundaeus V, Ahlman K, Jonsson IM, Mölne L, Lagergård T.

Microb Pathog. 2002 Aug;33(2):49-62.

PMID:
12202104
22.

The cytolethal distending toxin of Haemophilus ducreyi inhibits endothelial cell proliferation.

Svensson LA, Henning P, Lagergård T.

Infect Immun. 2002 May;70(5):2665-9.

23.

Novel tricyclic-alpha-alkyloxyphenylpropionic acids: dual PPARalpha/gamma agonists with hypolipidemic and antidiabetic activity.

Sauerberg P, Pettersson I, Jeppesen L, Bury PS, Mogensen JP, Wassermann K, Brand CL, Sturis J, Wöldike HF, Fleckner J, Andersen AS, Mortensen SB, Svensson LA, Rasmussen HB, Lehmann SV, Polivka Z, Sindelar K, Panajotova V, Ynddal L, Wulff EM.

J Med Chem. 2002 Feb 14;45(4):789-804.

PMID:
11831892
24.

In vitro and in vivo interactions of Haemophilus ducreyi with host phagocytes.

Ahmed HJ, Johansson C, Svensson LA, Ahlman K, Verdrengh M, Lagergård T.

Infect Immun. 2002 Feb;70(2):899-908.

25.

Cooperative zinc binding in a staphylococcal enterotoxin A mutant mimics the SEA-MHC class II interaction.

Håkansson M, Antonsson P, Björk P, Svensson LA.

J Biol Inorg Chem. 2001 Oct;6(8):757-62.

PMID:
11713682
26.

Prevalence of cdtABC genes encoding cytolethal distending toxin among Haemophilus ducreyi and Actinobacillus actinomycetemcomitans strains.

Ahmed HJ, Svensson LA, Cope LD, Latimer JL, Hansen EJ, Ahlman K, Bayat-Turk J, Klamer D, Lagergård T.

J Med Microbiol. 2001 Oct;50(10):860-4.

PMID:
11599734
27.

Symmetrical stabilization of bound Ca2+ ions in a cooperative pair of EF-hands through hydrogen bonding of coordinating water molecules in calbindin D(9k).

Fast J, Håkansson M, Muranyi A, Gippert GP, Thulin E, Evenäs J, Svensson LA, Linse S.

Biochemistry. 2001 Aug 21;40(33):9887-95.

PMID:
11502182
28.

Crystal structure of a superantigen bound to MHC class II displays zinc and peptide dependence.

Petersson K, Håkansson M, Nilsson H, Forsberg G, Svensson LA, Liljas A, Walse B.

EMBO J. 2001 Jul 2;20(13):3306-12.

29.

Direct separation of captopril diastereoisomers including their rotational isomers by RP-LC using a teicoplanin column.

Owens PK, Svensson LA, Vessman J.

J Pharm Biomed Anal. 2001 Jun;25(3-4):453-64.

PMID:
11377025
30.

The impact of Haemophilus ducreyi cytolethal distending toxin on cells involved in immune response.

Svensson LA, Tarkowski A, Thelestam M, Lagergård T.

Microb Pathog. 2001 Mar;30(3):157-66.

PMID:
11273741
31.

Crystal structure of the haloalkane dehalogenase from Sphingomonas paucimobilis UT26.

Marek J, Vévodová J, Smatanová IK, Nagata Y, Svensson LA, Newman J, Takagi M, Damborský J.

Biochemistry. 2000 Nov 21;39(46):14082-6.

PMID:
11087355
32.

The crystal structure of staphylococcal enterotoxin H: implications for binding properties to MHC class II and TcR molecules.

Hâkansson M, Petersson K, Nilsson H, Forsberg G, Björk P, Antonsson P, Svensson LA.

J Mol Biol. 2000 Sep 22;302(3):527-37.

PMID:
10986116
33.
34.

Polar organic phase liquid chromatography with packed capillary columns using a vancomycin chiral stationary phase

Svensson LA, Donnecke J, Karlsson KE, Karlsson A, Vessman J.

Chirality. 2000 Aug;12(8):606-13.

PMID:
10897097
35.

Immobilisation and evaluation of a vancomycin chiral stationary phase for capillary electrochromatography.

Wikström H, Svensson LA, Torstensson A, Owens PK.

J Chromatogr A. 2000 Feb 11;869(1-2):395-409.

PMID:
10720254
36.

Crystallization and preliminary X-ray analysis of birch-pollen allergen Bet v 1 in complex with a murine monoclonal IgG Fab' fragment.

Spangfort MD, Mirza O, Svensson LA, Larsen JN, Gajhede M, Ipsen H.

Acta Crystallogr D Biol Crystallogr. 1999 Dec;55(Pt 12):2035-6.

PMID:
10666582
37.
38.

Crystallization and preliminary X-ray diffraction analysis of haloalkane dehalogenase LinB from Sphingomonas paucimobilis UT26.

Smatanová I, Nagata Y, Svensson LA, Takagi M, Marek J.

Acta Crystallogr D Biol Crystallogr. 1999 Jun;55(Pt 6):1231-3.

PMID:
10329794
39.

Active suppression in orally tolerized rats coincides with in situ transforming growth factor-beta (TGF-beta) expression in the draining lymph nodes.

Lundin BS, Karlsson MR, Svensson LA, Hanson LA, Dahlgren UI, Telemo E.

Clin Exp Immunol. 1999 Apr;116(1):181-7.

40.

A structural and functional comparison of staphylococcal enterotoxins A and C2 reveals remarkable similarity and dissimilarity.

Schad EM, Papageorgiou AC, Svensson LA, Acharya KR.

J Mol Biol. 1997 Jun 6;269(2):270-80.

PMID:
9191070
41.

Structural basis for the negative allostery between Ca(2+)- and Mg(2+)-binding in the intracellular Ca(2+)-receptor calbindin D9k.

Andersson M, Malmendal A, Linse S, Ivarsson I, Forsén S, Svensson LA.

Protein Sci. 1997 Jun;6(6):1139-47.

42.

X-ray structure of a ribonuclease A-uridine vanadate complex at 1.3 A resolution.

Ladner JE, Wladkowski BD, Svensson LA, Sjölin L, Gilliland GL.

Acta Crystallogr D Biol Crystallogr. 1997 May 1;53(Pt 3):290-301.

PMID:
15299932
43.

Staphylococcal enterotoxins A, D, and E. Structure and function, including mechanism of T-cell superantigenicity.

Svensson LA, Schad EM, Sundström M, Antonsson P, Kalland T, Dohlsten M.

Prep Biochem Biotechnol. 1997 May-Aug;27(2-3):111-41. Review. No abstract available.

PMID:
9292923
44.

Crystallization and preliminary X-ray analysis of human dUTPase.

Larsson G, Nyman PO, Svensson LA.

Acta Crystallogr D Biol Crystallogr. 1996 Sep 1;52(Pt 5):1039-40.

PMID:
15299620
45.

Crystal structure of the Escherichia coli dUTPase in complex with a substrate analogue (dUDP).

Larsson G, Svensson LA, Nyman PO.

Nat Struct Biol. 1996 Jun;3(6):532-8.

PMID:
8646539
46.

Locating a local symmetry axis from patterson map cross vectors: application to crystal data from GroEl, GTP cyclohydrolase I and the proteosome.

Stubbs MT, Nar H, Löwe J, Huber R, Ladenstein R, Spangfort MD, Svensson LA.

Acta Crystallogr D Biol Crystallogr. 1996 May 1;52(Pt 3):447-52.

PMID:
15299665
47.

Crystal structure of the superantigen staphylococcal enterotoxin type A.

Schad EM, Zaitseva I, Zaitsev VN, Dohlsten M, Kalland T, Schlievert PM, Ohlendorf DH, Svensson LA.

EMBO J. 1995 Jul 17;14(14):3292-301.

48.

Identification of a new by-product detected in metoprolol tartrate.

Erickson M, Karlsson KE, Lamm B, Larsson S, Svensson LA, Vessman J.

J Pharm Biomed Anal. 1995 Apr;13(4-5):567-74.

PMID:
9696571
49.

Terbutaline prodrugs and oral beta 2-agonist therapy.

Svensson LA.

Pharmacol Toxicol. 1995;77 Suppl 3:30-3. No abstract available.

PMID:
8751147
50.

A calbindin D9k mutant with reduced calcium affinity and enhanced cooperativity. Metal ion binding, stability, and structural studies.

Linse S, Bylsma NR, Drakenberg T, Sellers P, Forsén S, Thulin E, Svensson LA, Zajtzeva I, Zajtsev V, Marek J.

Biochemistry. 1994 Oct 18;33(41):12478-86.

PMID:
7918470

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