Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 62

1.

LightGBM: An Effective and Scalable Algorithm for Prediction of Chemical Toxicity-Application to the Tox21 and Mutagenicity Data Sets.

Zhang J, Mucs D, Norinder U, Svensson F.

J Chem Inf Model. 2019 Oct 28;59(10):4150-4158. doi: 10.1021/acs.jcim.9b00633. Epub 2019 Oct 9.

PMID:
31560206
2.

Understanding Conditional Associations between ToxCast in Vitro Readouts and the Hepatotoxicity of Compounds Using Rule-Based Methods.

Mahmoud SY, Svensson F, Zoufir A, Módos D, Afzal AM, Bender A.

Chem Res Toxicol. 2019 Sep 20. doi: 10.1021/acs.chemrestox.8b00382. [Epub ahead of print]

PMID:
31442032
3.

The Nlrp6 inflammasome is not required for baseline colonic inner mucus layer formation or function.

Volk JK, Nyström EEL, van der Post S, Abad BM, Schroeder BO, Johansson Å, Svensson F, Jäverfelt S, Johansson MEV, Hansson GC, Birchenough GMH.

J Exp Med. 2019 Nov 4;216(11):2602-2618. doi: 10.1084/jem.20190679. Epub 2019 Aug 16.

PMID:
31420376
4.

Triazole-Pyridine Dicarbonitrile Targets Phosphodiesterase 4 to Induce Cytotoxicity in Lung Carcinoma Cells.

Keerthy HK, Mohan S, Basappa, Bharathkumar H, Rangappa S, Svensson F, Bender A, Mohan CD, Rangappa KS, Bhatnagar R.

Chem Biodivers. 2019 Sep;16(9):e1900234. doi: 10.1002/cbdv.201900234. Epub 2019 Aug 29.

PMID:
31287204
5.

Multitask Modeling with Confidence Using Matrix Factorization and Conformal Prediction.

Norinder U, Svensson F.

J Chem Inf Model. 2019 Apr 22;59(4):1598-1604. doi: 10.1021/acs.jcim.9b00027. Epub 2019 Apr 5.

PMID:
30908915
6.

Therapy for glioblastoma: is it working?

Zanders ED, Svensson F, Bailey DS.

Drug Discov Today. 2019 May;24(5):1193-1201. doi: 10.1016/j.drudis.2019.03.008. Epub 2019 Mar 13. Review.

7.

Scrutinizing the cut-off for "pathological" meniscal body extrusion on knee MRI.

Svensson F, Felson DT, Turkiewicz A, Guermazi A, Roemer FW, Neuman P, Englund M.

Eur Radiol. 2019 May;29(5):2616-2623. doi: 10.1007/s00330-018-5914-0. Epub 2019 Jan 10.

8.

The central exons of the human MUC2 and MUC6 mucins are highly repetitive and variable in sequence between individuals.

Svensson F, Lang T, Johansson MEV, Hansson GC.

Sci Rep. 2018 Nov 30;8(1):17503. doi: 10.1038/s41598-018-35499-w.

9.

WINDOW consortium: A path towards increased therapy efficacy against glioblastoma.

Abdul KU, Houweling M, Svensson F, Narayan RS, Cornelissen FMG, Küçükosmanoglu A, Metzakopian E, Watts C, Bailey D, Wurdinger T, Westerman BA.

Drug Resist Updat. 2018 Sep;40:17-24. doi: 10.1016/j.drup.2018.10.001. Epub 2018 Oct 30. Review.

PMID:
30439622
10.

Information-Derived Mechanistic Hypotheses for Structural Cardiotoxicity.

Svensson F, Zoufir A, Mahmoud S, Afzal AM, Smit I, Giblin KA, Clements PJ, Mettetal JT, Pointon A, Harvey JS, Greene N, Williams RV, Bender A.

Chem Res Toxicol. 2018 Nov 19;31(11):1119-1127. doi: 10.1021/acs.chemrestox.8b00159. Epub 2018 Oct 17.

PMID:
30350600
11.

Meniscal body extrusion and cartilage coverage in middle-aged and elderly without radiographic knee osteoarthritis.

Svensson F, Felson DT, Zhang F, Guermazi A, Roemer FW, Niu J, Aliabadi P, Neogi T, Englund M.

Eur Radiol. 2019 Apr;29(4):1848-1854. doi: 10.1007/s00330-018-5741-3. Epub 2018 Oct 2.

12.

GBM Drug Bank-a new resource for glioblastoma drug discovery and informatics research.

Svensson F, Westerman B, Würdinger T, Bailey D.

Neuro Oncol. 2018 Nov 12;20(12):1680-1681. doi: 10.1093/neuonc/noy122. No abstract available.

13.

Spring and Late Summer Phytoplankton Biomass Impact on the Coastal Sediment Microbial Community Structure.

Broman E, Li L, Fridlund J, Svensson F, Legrand C, Dopson M.

Microb Ecol. 2019 Feb;77(2):288-303. doi: 10.1007/s00248-018-1229-6. Epub 2018 Jul 17.

14.

Emerging patents in the therapeutic areas of glioma and glioblastoma.

Harris M, Svensson F, Kopanitsa L, Ladds G, Bailey D.

Expert Opin Ther Pat. 2018 Jul;28(7):573-590. doi: 10.1080/13543776.2018.1494155. Epub 2018 Jul 9. Review.

PMID:
29950117
15.

Conformal Regression for Quantitative Structure-Activity Relationship Modeling-Quantifying Prediction Uncertainty.

Svensson F, Aniceto N, Norinder U, Cortes-Ciriano I, Spjuth O, Carlsson L, Bender A.

J Chem Inf Model. 2018 May 29;58(5):1132-1140. doi: 10.1021/acs.jcim.8b00054. Epub 2018 May 10.

PMID:
29701973
16.

Hybrid Drug Delivery Patches Based on Spherical Cellulose Nanocrystals and Colloid Titania-Synthesis and Antibacterial Properties.

Evdokimova OL, Svensson FG, Agafonov AV, Håkansson S, Seisenbaeva GA, Kessler VG.

Nanomaterials (Basel). 2018 Apr 8;8(4). pii: E228. doi: 10.3390/nano8040228.

17.

Study of mucin turnover in the small intestine by in vivo labeling.

Schneider H, Pelaseyed T, Svensson F, Johansson MEV.

Sci Rep. 2018 Apr 10;8(1):5760. doi: 10.1038/s41598-018-24148-x.

18.

eMolTox: prediction of molecular toxicity with confidence.

Ji C, Svensson F, Zoufir A, Bender A.

Bioinformatics. 2018 Jul 15;34(14):2508-2509. doi: 10.1093/bioinformatics/bty135.

PMID:
29522123
19.

Maximizing gain in high-throughput screening using conformal prediction.

Svensson F, Afzal AM, Norinder U, Bender A.

J Cheminform. 2018 Feb 21;10(1):7. doi: 10.1186/s13321-018-0260-4.

20.

Pulsed-Wave Doppler Recordings in the Proximal Descending Aorta in Patients with Chronic Aortic Regurgitation: Insights from Cardiovascular Magnetic Resonance.

Bech-Hanssen O, Polte CL, Svensson F, Johnsson ÅA, Lagerstrand KM, Cederbom U, Gao SA.

J Am Soc Echocardiogr. 2018 Mar;31(3):304-313.e3. doi: 10.1016/j.echo.2017.11.011. Epub 2017 Dec 29.

PMID:
29290484
21.

Computer-aided design of multi-target ligands at A1R, A2AR and PDE10A, key proteins in neurodegenerative diseases.

Kalash L, Val C, Azuaje J, Loza MI, Svensson F, Zoufir A, Mervin L, Ladds G, Brea J, Glen R, Sotelo E, Bender A.

J Cheminform. 2017 Dec 30;9(1):67. doi: 10.1186/s13321-017-0249-4.

22.

Orthologue chemical space and its influence on target prediction.

Mervin LH, Bulusu KC, Kalash L, Afzal AM, Svensson F, Firth MA, Barrett I, Engkvist O, Bender A.

Bioinformatics. 2018 Jan 1;34(1):72-79. doi: 10.1093/bioinformatics/btx525.

23.

Characterization of complex flow patterns in the ascending aorta in patients with aortic regurgitation using conventional phase-contrast velocity MRI.

Bech-Hanssen O, Svensson F, Polte CL, Johnsson ÅA, Gao SA, Lagerstrand KM.

Int J Cardiovasc Imaging. 2018 Mar;34(3):419-429. doi: 10.1007/s10554-017-1239-3. Epub 2017 Sep 4.

24.

Fragment-Based Drug Discovery of Phosphodiesterase Inhibitors.

Svensson F, Bender A, Bailey D.

J Med Chem. 2018 Feb 22;61(4):1415-1424. doi: 10.1021/acs.jmedchem.7b00404. Epub 2017 Aug 11.

PMID:
28800229
25.

Prefrontal-hippocampal coupling by theta rhythm and by 2-5 Hz oscillation in the delta band: The role of the nucleus reuniens of the thalamus.

Roy A, Svensson FP, Mazeh A, Kocsis B.

Brain Struct Funct. 2017 Aug;222(6):2819-2830. doi: 10.1007/s00429-017-1374-6. Epub 2017 Feb 16.

26.

Improving Screening Efficiency through Iterative Screening Using Docking and Conformal Prediction.

Svensson F, Norinder U, Bender A.

J Chem Inf Model. 2017 Mar 27;57(3):439-444. doi: 10.1021/acs.jcim.6b00532. Epub 2017 Feb 28.

PMID:
28195474
27.

A Decision support system (DSS) for municipal nurses encountering health deterioration among older people.

Kihlgren A, Svensson F, Lövbrand C, Gifford M, Adolfsson A.

BMC Nurs. 2016 Nov 8;15:63. eCollection 2016.

28.

Modelling compound cytotoxicity using conformal prediction and PubChem HTS data.

Svensson F, Norinder U, Bender A.

Toxicol Res (Camb). 2016 Oct 31;6(1):73-80. doi: 10.1039/c6tx00252h. eCollection 2017 Jan 1.

29.

Evaluation of a corrected implementation of a method of simulating pulmonary nodules in chest tomosynthesis.

Svensson F, Söderman C, Svalkvist A, Rossi Norrlund R, Vikgren J, Johnsson ÅA, Båth M.

Acta Radiol. 2017 Apr;58(4):408-413. doi: 10.1177/0284185116654330. Epub 2016 Sep 30.

PMID:
27382042
30.

Risk factors for meniscal body extrusion on MRI in subjects free of radiographic knee osteoarthritis: longitudinal data from the Osteoarthritis Initiative.

Zhang F, Kumm J, Svensson F, Turkiewicz A, Frobell R, Englund M.

Osteoarthritis Cartilage. 2016 May;24(5):801-6. doi: 10.1016/j.joca.2015.12.003. Epub 2015 Dec 17.

31.

Normalization of Host Intestinal Mucus Layers Requires Long-Term Microbial Colonization.

Johansson ME, Jakobsson HE, Holmén-Larsson J, Schütte A, Ermund A, Rodríguez-Piñeiro AM, Arike L, Wising C, Svensson F, Bäckhed F, Hansson GC.

Cell Host Microbe. 2015 Nov 11;18(5):582-92. doi: 10.1016/j.chom.2015.10.007. Epub 2015 Oct 29.

32.

Virtual Screening for Transition State Analogue Inhibitors of IRAP Based on Quantum Mechanically Derived Reaction Coordinates.

Svensson F, Engen K, Lundbäck T, Larhed M, Sköld C.

J Chem Inf Model. 2015 Sep 28;55(9):1984-93. doi: 10.1021/acs.jcim.5b00359. Epub 2015 Aug 14.

PMID:
26252078
33.

Health-Related Quality-of-Life (HRQoL) on an Average of 12 Years After Gastric Bypass Surgery.

Raoof M, Näslund I, Rask E, Karlsson J, Sundbom M, Edholm D, Karlsson FA, Svensson F, Szabo E.

Obes Surg. 2015 Jul;25(7):1119-27. doi: 10.1007/s11695-014-1513-6.

PMID:
25566743
34.

Toward a benchmarking data set able to evaluate ligand- and structure-based virtual screening using public HTS data.

Lindh M, Svensson F, Schaal W, Zhang J, Sköld C, Brandt P, Karlén A.

J Chem Inf Model. 2015 Feb 23;55(2):343-53. doi: 10.1021/ci5005465. Epub 2015 Jan 28.

PMID:
25564966
35.

Inhibition of Insulin-Regulated Aminopeptidase (IRAP) by Arylsulfonamides.

Borhade SR, Rosenström U, Sävmarker J, Lundbäck T, Jenmalm-Jensen A, Sigmundsson K, Axelsson H, Svensson F, Konda V, Sköld C, Larhed M, Hallberg M.

ChemistryOpen. 2014 Dec;3(6):256-63. doi: 10.1002/open.201402027. Epub 2014 Nov 21.

36.

Palladium(II)-catalyzed desulfitative synthesis of aryl ketones from sodium arylsulfinates and nitriles: scope, limitations, and mechanistic studies.

Skillinghaug B, Sköld C, Rydfjord J, Svensson F, Behrends M, Sävmarker J, Sjöberg PJ, Larhed M.

J Org Chem. 2014 Dec 19;79(24):12018-32. doi: 10.1021/jo501875n. Epub 2014 Oct 31.

PMID:
25295849
37.

Diatom cell size, coloniality and motility: trade-offs between temperature, salinity and nutrient supply with climate change.

Svensson F, Norberg J, Snoeijs P.

PLoS One. 2014 Oct 3;9(10):e109993. doi: 10.1371/journal.pone.0109993. eCollection 2014.

38.

The mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system.

Pelaseyed T, Bergström JH, Gustafsson JK, Ermund A, Birchenough GM, Schütte A, van der Post S, Svensson F, Rodríguez-Piñeiro AM, Nyström EE, Wising C, Johansson ME, Hansson GC.

Immunol Rev. 2014 Jul;260(1):8-20. doi: 10.1111/imr.12182. Review.

39.

Meniscus body position and its change over four years in asymptomatic adults: a cohort study using data from the Osteoarthritis Initiative (OAI).

Bruns K, Svensson F, Turkiewicz A, Wirth W, Guermazi A, Eckstein F, Englund M.

BMC Musculoskelet Disord. 2014 Feb 5;15:32. doi: 10.1186/1471-2474-15-32.

40.

Temperature measurements with two different IR sensors in a continuous-flow microwave heated system.

Rydfjord J, Svensson F, Fagrell M, Sävmarker J, Thulin M, Larhed M.

Beilstein J Org Chem. 2013 Oct 10;9:2079-87. doi: 10.3762/bjoc.9.244. eCollection 2013.

41.

Decarboxylative palladium(II)-catalyzed synthesis of aryl amidines from aryl carboxylic acids: development and mechanistic investigation.

Rydfjord J, Svensson F, Trejos A, Sjöberg PJ, Sköld C, Sävmarker J, Odell LR, Larhed M.

Chemistry. 2013 Oct 4;19(41):13803-10. doi: 10.1002/chem.201301809. Epub 2013 Aug 28.

42.

Adolescents' lifetime experience of selling sex: development over five years.

Fredlund C, Svensson F, Svedin CG, Priebe G, Wadsby M.

J Child Sex Abus. 2013;22(3):312-25. doi: 10.1080/10538712.2013.743950.

PMID:
23590352
43.

Unfolding dynamics of the mucin SEA domain probed by force spectroscopy suggest that it acts as a cell-protective device.

Pelaseyed T, Zäch M, Petersson AC, Svensson F, Johansson DG, Hansson GC.

FEBS J. 2013 Mar;280(6):1491-501. doi: 10.1111/febs.12144. Epub 2013 Feb 21.

44.

Adolescents selling sex: exposure to abuse, mental health, self-harm behaviour and the need for help and support--a study of a Swedish national sample.

Svensson F, Fredlund C, Svedin CG, Priebe G, Wadsby M.

Nord J Psychiatry. 2013 Apr;67(2):81-8. doi: 10.3109/08039488.2012.679968. Epub 2012 May 8.

PMID:
22563767
45.

Long-term results 11 years after primary gastric bypass in 384 patients.

Edholm D, Svensson F, Näslund I, Karlsson FA, Rask E, Sundbom M.

Surg Obes Relat Dis. 2013 Sep-Oct;9(5):708-13. doi: 10.1016/j.soard.2012.02.011. Epub 2012 Mar 23.

PMID:
22551577
46.

Effects of chirality on the intracellular localization of binuclear ruthenium(II) polypyridyl complexes.

Svensson FR, Andersson J, Åmand HL, Lincoln P.

J Biol Inorg Chem. 2012 Apr;17(4):565-71. doi: 10.1007/s00775-012-0877-0. Epub 2012 Feb 5.

47.

Virtual screening data fusion using both structure- and ligand-based methods.

Svensson F, Karlén A, Sköld C.

J Chem Inf Model. 2012 Jan 23;52(1):225-32. doi: 10.1021/ci2004835. Epub 2011 Dec 22.

PMID:
22148635
48.

Recombinant glycoprotein E produced in mammalian cells in large-scale as an antigen for varicella-zoster-virus serology.

Thomsson E, Persson L, Grahn A, Snäll J, Ekblad M, Brunhage E, Svensson F, Jern C, Hansson GC, Bäckström M, Bergström T.

J Virol Methods. 2011 Jul;175(1):53-9. doi: 10.1016/j.jviromet.2011.04.014. Epub 2011 Apr 22.

PMID:
21540058
49.

Ruthenium(II) Complex Enantiomers as Cellular Probes for Diastereomeric Interactions in Confocal and Fluorescence Lifetime Imaging Microscopy.

Svensson FR, Abrahamsson M, Strömberg N, Ewing AG, Lincoln P.

J Phys Chem Lett. 2011 Feb 7;2(5):397-401.

50.

Correlation between cellular localization and binding preference to RNA, DNA, and phospholipid membrane for luminescent ruthenium(II) complexes.

Matson M, Svensson FR, Nordén B, Lincoln P.

J Phys Chem B. 2011 Feb 24;115(7):1706-11. doi: 10.1021/jp109530f. Epub 2011 Feb 2.

PMID:
21287998

Supplemental Content

Loading ...
Support Center