Sort by
Items per page

Send to

Choose Destination

Search results

Items: 31


Auranofin Activity Exposes Thioredoxin Reductase as a Viable Drug Target in Mycobacterium abscessus.

Ruth MM, van Rossum M, Koeken VACM, Pennings LJ, Svensson EM, Ruesen C, Bowles EC, Wertheim HFL, Hoefsloot W, van Ingen J.

Antimicrob Agents Chemother. 2019 Aug 23;63(9). pii: e00449-19. doi: 10.1128/AAC.00449-19. Print 2019 Sep.


Clinical Pharmacokinetics and Pharmacodynamics of Rifampicin in Human Tuberculosis.

Abulfathi AA, Decloedt EH, Svensson EM, Diacon AH, Donald P, Reuter H.

Clin Pharmacokinet. 2019 Sep;58(9):1103-1129. doi: 10.1007/s40262-019-00764-2. Review.


Megalithic tombs in western and northern Neolithic Europe were linked to a kindred society.

Sánchez-Quinto F, Malmström H, Fraser M, Girdland-Flink L, Svensson EM, Simões LG, George R, Hollfelder N, Burenhult G, Noble G, Britton K, Talamo S, Curtis N, Brzobohata H, Sumberova R, Götherström A, Storå J, Jakobsson M.

Proc Natl Acad Sci U S A. 2019 May 7;116(19):9469-9474. doi: 10.1073/pnas.1818037116. Epub 2019 Apr 15.


Personalized Tuberculosis Treatment Through Model-Informed Dosing of Rifampicin.

van Beek SW, Ter Heine R, Keizer RJ, Magis-Escurra C, Aarnoutse RE, Svensson EM.

Clin Pharmacokinet. 2019 Jun;58(6):815-826. doi: 10.1007/s40262-018-00732-2.


Protein binding of rifampicin is not saturated when using high-dose rifampicin.

Litjens CHC, Aarnoutse RE, van Ewijk-Beneken Kolmer EWJ, Svensson EM, Colbers A, Burger DM, Boeree MJ, Te Brake LHM; PanACEA-MAMS-TB-01 Team .

J Antimicrob Chemother. 2019 Apr 1;74(4):986-990. doi: 10.1093/jac/dky527.


Relative bioavailability of bedaquiline tablets suspended in water: Implications for dosing in children.

Svensson EM, du Bois J, Kitshoff R, de Jager VR, Wiesner L, Norman J, Nachman S, Smith B, Diacon AH, Hesseling AC, Garcia-Prats AJ.

Br J Clin Pharmacol. 2018 Jun 27. doi: 10.1111/bcp.13696. [Epub ahead of print]


The Potential for Treatment Shortening With Higher Rifampicin Doses: Relating Drug Exposure to Treatment Response in Patients With Pulmonary Tuberculosis.

Svensson EM, Svensson RJ, Te Brake LHM, Boeree MJ, Heinrich N, Konsten S, Churchyard G, Dawson R, Diacon AH, Kibiki GS, Minja LT, Ntingiya NE, Sanne I, Gillespie SH, Hoelscher M, Phillips PPJ, Simonsson USH, Aarnoutse R.

Clin Infect Dis. 2018 Jun 18;67(1):34-41. doi: 10.1093/cid/ciy026.


Greater Early Bactericidal Activity at Higher Rifampicin Doses Revealed by Modeling and Clinical Trial Simulations.

Svensson RJ, Svensson EM, Aarnoutse RE, Diacon AH, Dawson R, Gillespie SH, Moodley M, Boeree MJ, Simonsson USH.

J Infect Dis. 2018 Aug 14;218(6):991-999. doi: 10.1093/infdis/jiy242.


Current status of pharmacokinetic and safety studies of multidrug-resistant tuberculosis treatment in children.

Garcia-Prats AJ, Svensson EM, Weld ED, Schaaf HS, Hesseling AC.

Int J Tuberc Lung Dis. 2018 May 1;22(5):15-23. doi: 10.5588/ijtld.17.0355. Review.


Four millennia of Iberian biomolecular prehistory illustrate the impact of prehistoric migrations at the far end of Eurasia.

Valdiosera C, Günther T, Vera-Rodríguez JC, Ureña I, Iriarte E, Rodríguez-Varela R, Simões LG, Martínez-Sánchez RM, Svensson EM, Malmström H, Rodríguez L, Bermúdez de Castro JM, Carbonell E, Alday A, Hernández Vera JA, Götherström A, Carretero JM, Arsuaga JL, Smith CI, Jakobsson M.

Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):3428-3433. doi: 10.1073/pnas.1717762115. Epub 2018 Mar 12.


Population genomics of Mesolithic Scandinavia: Investigating early postglacial migration routes and high-latitude adaptation.

Günther T, Malmström H, Svensson EM, Omrak A, Sánchez-Quinto F, Kılınç GM, Krzewińska M, Eriksson G, Fraser M, Edlund H, Munters AR, Coutinho A, Simões LG, Vicente M, Sjölander A, Jansen Sellevold B, Jørgensen R, Claes P, Shriver MD, Valdiosera C, Netea MG, Apel J, Lidén K, Skar B, Storå J, Götherström A, Jakobsson M.

PLoS Biol. 2018 Jan 9;16(1):e2003703. doi: 10.1371/journal.pbio.2003703. eCollection 2018 Jan.


Pharmacokinetic interaction between bedaquiline and clofazimine in patients with drug-resistant tuberculosis.

Maartens G, Brill MJE, Pandie M, Svensson EM.

Int J Tuberc Lung Dis. 2018 Jan 1;22(1):26-29. doi: 10.5588/ijtld.17.0615. Epub 2017 Nov 16.


Modelling of mycobacterial load reveals bedaquiline's exposure-response relationship in patients with drug-resistant TB.

Svensson EM, Karlsson MO.

J Antimicrob Chemother. 2017 Dec 1;72(12):3398-3405. doi: 10.1093/jac/dkx317.


Evidence-Based Design of Fixed-Dose Combinations: Principles and Application to Pediatric Anti-Tuberculosis Therapy.

Svensson EM, Yngman G, Denti P, McIlleron H, Kjellsson MC, Karlsson MO.

Clin Pharmacokinet. 2018 May;57(5):591-599. doi: 10.1007/s40262-017-0577-6.


Confirming model-predicted pharmacokinetic interactions between bedaquiline and lopinavir/ritonavir or nevirapine in patients with HIV and drug-resistant tuberculosis.

Brill MJ, Svensson EM, Pandie M, Maartens G, Karlsson MO.

Int J Antimicrob Agents. 2017 Feb;49(2):212-217. doi: 10.1016/j.ijantimicag.2016.10.020. Epub 2016 Dec 14.


Population Pharmacokinetics of Bedaquiline and Metabolite M2 in Patients With Drug-Resistant Tuberculosis: The Effect of Time-Varying Weight and Albumin.

Svensson EM, Dosne AG, Karlsson MO.

CPT Pharmacometrics Syst Pharmacol. 2016 Dec;5(12):682-691. doi: 10.1002/psp4.12147. Epub 2016 Nov 8.


The mitogenome of a 35,000-year-old Homo sapiens from Europe supports a Palaeolithic back-migration to Africa.

Hervella M, Svensson EM, Alberdi A, Günther T, Izagirre N, Munters AR, Alonso S, Ioana M, Ridiche F, Soficaru A, Jakobsson M, Netea MG, de-la-Rua C.

Sci Rep. 2016 May 19;6:25501. doi: 10.1038/srep25501.


Population pharmacokinetic drug-drug interaction pooled analysis of existing data for rifabutin and HIV PIs.

Hennig S, Svensson EM, Niebecker R, Fourie PB, Weiner MH, Bonora S, Peloquin CA, Gallicano K, Flexner C, Pym A, Vis P, Olliaro PL, McIlleron H, Karlsson MO.

J Antimicrob Chemother. 2016 May;71(5):1330-40. doi: 10.1093/jac/dkv470. Epub 2016 Jan 31.


Genomic Evidence Establishes Anatolia as the Source of the European Neolithic Gene Pool.

Omrak A, Günther T, Valdiosera C, Svensson EM, Malmström H, Kiesewetter H, Aylward W, Storå J, Jakobsson M, Götherström A.

Curr Biol. 2016 Jan 25;26(2):270-275. doi: 10.1016/j.cub.2015.12.019. Epub 2015 Dec 31.


Pharmacokinetic Interactions for Drugs with a Long Half-Life—Evidence for the Need of Model-Based Analysis.

Svensson EM, Acharya C, Clauson B, Dooley KE, Karlsson MO.

AAPS J. 2016 Jan;18(1):171-9.


Ancient genomes link early farmers from Atapuerca in Spain to modern-day Basques.

Günther T, Valdiosera C, Malmström H, Ureña I, Rodriguez-Varela R, Sverrisdóttir ÓO, Daskalaki EA, Skoglund P, Naidoo T, Svensson EM, Bermúdez de Castro JM, Carbonell E, Dunn M, Storå J, Iriarte E, Arsuaga JL, Carretero JM, Götherström A, Jakobsson M.

Proc Natl Acad Sci U S A. 2015 Sep 22;112(38):11917-22. doi: 10.1073/pnas.1509851112. Epub 2015 Sep 8.


Rifampicin and rifapentine significantly reduce concentrations of bedaquiline, a new anti-TB drug.

Svensson EM, Murray S, Karlsson MO, Dooley KE.

J Antimicrob Chemother. 2015 Apr;70(4):1106-14. doi: 10.1093/jac/dku504. Epub 2014 Dec 21.


[Compulsory outpatient treatment can prevent involuntary commitment].

Hansen LN, Svensson EM, Brandt-Christensen AM.

Ugeskr Laeger. 2014 Apr 14;176(16). pii: V12130698. Danish.


Impact of lopinavir-ritonavir or nevirapine on bedaquiline exposures and potential implications for patients with tuberculosis-HIV coinfection.

Svensson EM, Dooley KE, Karlsson MO.

Antimicrob Agents Chemother. 2014 Nov;58(11):6406-12. doi: 10.1128/AAC.03246-14. Epub 2014 Aug 11.


Use of a linearization approximation facilitating stochastic model building.

Svensson EM, Karlsson MO.

J Pharmacokinet Pharmacodyn. 2014 Apr;41(2):153-8. doi: 10.1007/s10928-014-9353-5. Epub 2014 Mar 13.


Medieval cattle from Bern (Switzerland): an archaeozoological, genetic and historical approach.

Svensson EM, Häsler S, Nussbaumer M, Rehazek A, Omrak A, Götherström A.

Schweiz Arch Tierheilkd. 2014 Jan;156(1):17-26. doi: 10.1024/0036-7281/a000542.


Model-based estimates of the effects of efavirenz on bedaquiline pharmacokinetics and suggested dose adjustments for patients coinfected with HIV and tuberculosis.

Svensson EM, Aweeka F, Park JG, Marzan F, Dooley KE, Karlsson MO.

Antimicrob Agents Chemother. 2013 Jun;57(6):2780-7. doi: 10.1128/AAC.00191-13. Epub 2013 Apr 9.


Coat colour and sex identification in horses from Iron Age Sweden.

Svensson EM, Telldahl Y, Sjöling E, Sundkvist A, Hulth H, Sjøvold T, Götherström A.

Ann Anat. 2012 Jan 20;194(1):82-7. doi: 10.1016/j.aanat.2011.11.001. Epub 2011 Nov 17.


Physcomitrella patens: a model to investigate the role of RAC/ROP GTPase signalling in tip growth.

Eklund DM, Svensson EM, Kost B.

J Exp Bot. 2010 Apr;61(7):1917-37. doi: 10.1093/jxb/erq080. Epub 2010 Apr 5.


Tracing genetic change over time using nuclear SNPs in ancient and modern cattle.

Svensson EM, Anderung C, Baubliene J, Persson P, Malmström H, Smith C, Vretemark M, Daugnora L, Götherström A.

Anim Genet. 2007 Aug;38(4):378-83. Epub 2007 Jun 26.


More on contamination: the use of asymmetric molecular behavior to identify authentic ancient human DNA.

Malmström H, Svensson EM, Gilbert MT, Willerslev E, Götherström A, Holmlund G.

Mol Biol Evol. 2007 Apr;24(4):998-1004. Epub 2007 Jan 25.


Supplemental Content

Loading ...
Support Center