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Items: 1 to 50 of 83

1.

NF-κB-Associated Pain-Related Neuropeptide Expression in Patients with Degenerative Disc Disease.

Ahmed AS, Berg S, Alkass K, Druid H, Hart DA, Svensson CI, Kosek E.

Int J Mol Sci. 2019 Feb 3;20(3). pii: E658. doi: 10.3390/ijms20030658.

2.

Spatial organization of the somatosensory cortex revealed by osmFISH.

Codeluppi S, Borm LE, Zeisel A, La Manno G, van Lunteren JA, Svensson CI, Linnarsson S.

Nat Methods. 2018 Nov;15(11):932-935. doi: 10.1038/s41592-018-0175-z. Epub 2018 Oct 30.

PMID:
30377364
3.

Characterization of neuroinflammation and periphery-to-CNS inflammatory cross-talk in patients with disc herniation and degenerative disc disease.

Palada V, Ahmed AS, Finn A, Berg S, Svensson CI, Kosek E.

Brain Behav Immun. 2019 Jan;75:60-71. doi: 10.1016/j.bbi.2018.09.010. Epub 2018 Sep 22.

4.

Exploring the transcriptome of resident spinal microglia after collagen antibody-induced arthritis.

Fernandez-Zafra T, Gao T, Jurczak A, Sandor K, Hore Z, Agalave NM, Su J, Estelius J, Lampa J, Hokfelt T, Wiesenfeld-Hallin Z, Xu X, Denk F, Svensson CI.

Pain. 2019 Jan;160(1):224-236. doi: 10.1097/j.pain.0000000000001394.

5.

Pain pathogenesis in rheumatoid arthritis-what have we learned from animal models?

Krock E, Jurczak A, Svensson CI.

Pain. 2018 Sep;159 Suppl 1:S98-S109. doi: 10.1097/j.pain.0000000000001333. No abstract available.

PMID:
30113954
6.

Pathogenic Citrulline-Multispecific B Cell Receptor Clades in Rheumatoid Arthritis.

Titcombe PJ, Wigerblad G, Sippl N, Zhang N, Shmagel AK, Sahlström P, Zhang Y, Barsness LO, Ghodke-Puranik Y, Baharpoor A, Hansson M, Israelsson L, Skriner K, Niewold TB, Klareskog L, Svensson CI, Amara K, Malmström V, Mueller DL.

Arthritis Rheumatol. 2018 Dec;70(12):1933-1945. doi: 10.1002/art.40590. Epub 2018 Oct 18.

PMID:
29927106
7.

Sinomenine alleviates mechanical hypersensitivity in mice with experimentally induced rheumatoid arthritis.

Gao T, Shi T, Wiesenfeld-Hallin Z, Svensson CI, Xu XJ.

Scand J Pain. 2015 Apr 1;7(1):9-14. doi: 10.1016/j.sjpain.2014.12.003.

PMID:
29911599
8.

Pathophysiology of chronic pain in cerebral palsy: implications for pharmacological treatment and research.

Blackman JA, Svensson CI, Marchand S.

Dev Med Child Neurol. 2018 Sep;60(9):861-865. doi: 10.1111/dmcn.13930. Epub 2018 Jun 7. Review.

PMID:
29882358
9.

The human CSF pain proteome.

Khoonsari PE, Ossipova E, Lengqvist J, Svensson CI, Kosek E, Kadetoff D, Jakobsson PJ, Kultima K, Lampa J.

J Proteomics. 2019 Jan 6;190:67-76. doi: 10.1016/j.jprot.2018.05.012. Epub 2018 May 28.

PMID:
29852297
10.

Cardiomyopathy, oxidative stress and impaired contractility in a rheumatoid arthritis mouse model.

Pironti G, Bersellini-Farinotti A, Agalave NM, Sandor K, Fernandez-Zafra T, Jurczak A, Lund LH, Svensson CI, Andersson DC.

Heart. 2018 Dec;104(24):2026-2034. doi: 10.1136/heartjnl-2018-312979. Epub 2018 May 26.

PMID:
29804097
11.

Spinal injection of newly identified cerebellin-1 and cerebellin-2 peptides induce mechanical hypersensitivity in mice.

Sandor K, Krishnan S, Agalave NM, Krock E, Salcido JV, Fernandez-Zafra T, Khoonsari PE, Svensson CI, Kultima K.

Neuropeptides. 2018 Jun;69:53-59. doi: 10.1016/j.npep.2018.04.004. Epub 2018 Apr 14.

PMID:
29705514
12.

Systematic analysis of the cerebrospinal fluid proteome of fibromyalgia patients.

Khoonsari PE, Musunri S, Herman S, Svensson CI, Tanum L, Gordh T, Kultima K.

J Proteomics. 2019 Jan 6;190:35-43. doi: 10.1016/j.jprot.2018.04.014. Epub 2018 Apr 12.

PMID:
29656018
13.

Autoantibodies Hurt: Transfer of Patient-Derived CASPR2 Antibodies Induces Neuropathic Pain in Mice.

Hunt MA, Nascimento DSM, Bersellini Farinotti A, Svensson CI.

Neuron. 2018 Feb 21;97(4):729-731. doi: 10.1016/j.neuron.2018.02.008.

PMID:
29470963
14.

Effect of intrathecal glucocorticoids on the central glucocorticoid receptor in a rat nerve ligation model.

Rijsdijk M, Agalave NM, van Wijck AJM, Kalkman CJ, Ramachandran R, Baharpoor A, Svensson CI, Yaksh TL.

Scand J Pain. 2017 Jul;16:1-9. doi: 10.1016/j.sjpain.2016.12.008. Epub 2017 Feb 3.

PMID:
28850381
15.

Inflammation-induced GluA1 trafficking and membrane insertion of Ca2+ permeable AMPA receptors in dorsal horn neurons is dependent on spinal tumor necrosis factor, PI3 kinase and protein kinase A.

Wigerblad G, Huie JR, Yin HZ, Leinders M, Pritchard RA, Koehrn FJ, Xiao WH, Bennett GJ, Huganir RL, Ferguson AR, Weiss JH, Svensson CI, Sorkin LS.

Exp Neurol. 2017 Jul;293:144-158. doi: 10.1016/j.expneurol.2017.04.004. Epub 2017 Apr 12.

16.

Mechanisms leading from systemic autoimmunity to joint-specific disease in rheumatoid arthritis.

Catrina AI, Svensson CI, Malmström V, Schett G, Klareskog L.

Nat Rev Rheumatol. 2017 Feb;13(2):79-86. doi: 10.1038/nrrheum.2016.200. Epub 2016 Dec 15. Review.

PMID:
27974851
17.

Cross-centre replication of suppressed burrowing behaviour as an ethologically relevant pain outcome measure in the rat: a prospective multicentre study.

Wodarski R, Delaney A, Ultenius C, Morland R, Andrews N, Baastrup C, Bryden LA, Caspani O, Christoph T, Gardiner NJ, Huang W, Kennedy JD, Koyama S, Li D, Ligocki M, Lindsten A, Machin I, Pekcec A, Robens A, Rotariu SM, VoB S, Segerdahl M, Stenfors C, Svensson CI, Treede RD, Uto K, Yamamoto K, Rutten K, Rice AS.

Pain. 2016 Oct;157(10):2350-2365.

PMID:
27820160
18.

Cross-centre replication of suppressed burrowing behaviour as an ethologically relevant pain outcome measure in the rat: a prospective multicentre study.

Wodarski R, Delaney A, Ultenius C, Morland R, Andrews N, Baastrup C, Bryden LA, Caspani O, Christoph T, Gardiner NJ, Huang W, Kennedy JD, Koyama S, Li D, Ligocki M, Lindsten A, Machin I, Pekcec A, Robens A, Rotariu SM, Vo S, Segerdahl M, Stenfors C, Svensson CI, Treede RD, Uto K, Yamamoto K, Rutten K, Rice AS.

Pain. 2016 Oct;157(10):2350-65. doi: 10.1097/j.pain.0000000000000657.

19.

Pattern recognition receptors in chronic pain: Mechanisms and therapeutic implications.

Kato J, Agalave NM, Svensson CI.

Eur J Pharmacol. 2016 Oct 5;788:261-273. doi: 10.1016/j.ejphar.2016.06.039. Epub 2016 Jun 23. Review.

PMID:
27343378
20.

Pain in rheumatoid arthritis: models and mechanisms.

Bas DB, Su J, Wigerblad G, Svensson CI.

Pain Manag. 2016;6(3):265-84. doi: 10.2217/pmt.16.4. Epub 2016 Apr 18. Review.

PMID:
27086843
21.

Dietary nitrate improves cardiac contractility via enhanced cellular Ca²⁺ signaling.

Pironti G, Ivarsson N, Yang J, Farinotti AB, Jonsson W, Zhang SJ, Bas D, Svensson CI, Westerblad H, Weitzberg E, Lundberg JO, Pernow J, Lanner J, Andersson DC.

Basic Res Cardiol. 2016 May;111(3):34. doi: 10.1007/s00395-016-0551-8. Epub 2016 Apr 12.

PMID:
27071401
22.

Analgesic properties of intrathecal glucocorticoids in three well established preclinical pain models.

Rijsdijk M, Svensson CI, Wijck AJ, Kalkman CJ, Yaksh TL.

Scand J Pain. 2016 Jan;10:90-102. doi: 10.1016/j.sjpain.2015.10.006. Epub 2015 Nov 20.

PMID:
28361779
23.

Ensuring transparency and minimization of methodologic bias in preclinical pain research: PPRECISE considerations.

Andrews NA, Latrémolière A, Basbaum AI, Mogil JS, Porreca F, Rice AS, Woolf CJ, Currie GL, Dworkin RH, Eisenach JC, Evans S, Gewandter JS, Gover TD, Handwerker H, Huang W, Iyengar S, Jensen MP, Kennedy JD, Lee N, Levine J, Lidster K, Machin I, McDermott MP, McMahon SB, Price TJ, Ross SE, Scherrer G, Seal RP, Sena ES, Silva E, Stone L, Svensson CI, Turk DC, Whiteside G.

Pain. 2016 Apr;157(4):901-9. doi: 10.1097/j.pain.0000000000000458. Review.

24.

A genome-wide association study of kynurenic acid in cerebrospinal fluid: implications for psychosis and cognitive impairment in bipolar disorder.

Sellgren CM, Kegel ME, Bergen SE, Ekman CJ, Olsson S, Larsson M, Vawter MP, Backlund L, Sullivan PF, Sklar P, Smoller JW, Magnusson PK, Hultman CM, Walther-Jallow L, Svensson CI, Lichtenstein P, Schalling M, Engberg G, Erhardt S, Landén M.

Mol Psychiatry. 2016 Oct;21(10):1342-50. doi: 10.1038/mp.2015.186. Epub 2015 Dec 15.

25.

Autoantibodies to citrullinated proteins induce joint pain independent of inflammation via a chemokine-dependent mechanism.

Wigerblad G, Bas DB, Fernades-Cerqueira C, Krishnamurthy A, Nandakumar KS, Rogoz K, Kato J, Sandor K, Su J, Jimenez-Andrade JM, Finn A, Bersellini Farinotti A, Amara K, Lundberg K, Holmdahl R, Jakobsson PJ, Malmström V, Catrina AI, Klareskog L, Svensson CI.

Ann Rheum Dis. 2016 Apr;75(4):730-8. doi: 10.1136/annrheumdis-2015-208094. Epub 2015 Nov 27.

26.

The effect of gabapentin and ketorolac on allodynia and conditioned place preference in antibody-induced inflammation.

Park HJ, Sandor K, McQueen J, Woller SA, Svensson CI, Corr M, Yaksh TL.

Eur J Pain. 2016 Jul;20(6):917-25. doi: 10.1002/ejp.816. Epub 2015 Oct 30.

27.

Delayed Imatinib Treatment for Acute Spinal Cord Injury: Functional Recovery and Serum Biomarkers.

Kjell J, Finn A, Hao J, Wellfelt K, Josephson A, Svensson CI, Wiesenfeld-Hallin Z, Eriksson U, Abrams M, Olson L.

J Neurotrauma. 2015 Nov 1;32(21):1645-57. doi: 10.1089/neu.2014.3863. Epub 2015 Jun 11.

28.

Using gait analysis to assess weight bearing in rats with Freund׳s complete adjuvant-induced monoarthritis to improve predictivity: Interfering with the cyclooxygenase and nerve growth factor pathways.

Ängeby Möller K, Berge OG, Finn A, Stenfors C, Svensson CI.

Eur J Pharmacol. 2015 Jun 5;756:75-84. doi: 10.1016/j.ejphar.2015.02.050. Epub 2015 Mar 16.

PMID:
25792342
29.

Role of extracellular damage-associated molecular pattern molecules (DAMPs) as mediators of persistent pain.

Kato J, Svensson CI.

Prog Mol Biol Transl Sci. 2015;131:251-79. doi: 10.1016/bs.pmbts.2014.11.014. Epub 2015 Jan 30. Review.

PMID:
25744676
30.

Phenotypic changes in dorsal root ganglion and spinal cord in the collagen antibody-induced arthritis mouse model.

Su J, Gao T, Shi T, Xiang Q, Xu X, Wiesenfeld-Hallin Z, Hökfelt T, Svensson CI.

J Comp Neurol. 2015 Jul 1;523(10):1505-28. doi: 10.1002/cne.23749. Epub 2015 Mar 26.

PMID:
25631752
31.

Extracellular high-mobility group box 1 protein (HMGB1) as a mediator of persistent pain.

Agalave NM, Svensson CI.

Mol Med. 2015 Feb 5;20:569-78. doi: 10.2119/molmed.2014.00176. Review.

32.

Spinal HMGB1 induces TLR4-mediated long-lasting hypersensitivity and glial activation and regulates pain-like behavior in experimental arthritis.

Agalave NM, Larsson M, Abdelmoaty S, Su J, Baharpoor A, Lundbäck P, Palmblad K, Andersson U, Harris H, Svensson CI.

Pain. 2014 Sep;155(9):1802-13. doi: 10.1016/j.pain.2014.06.007. Epub 2014 Jun 20.

PMID:
24954167
33.

Spinal release of tumour necrosis factor activates c-Jun N-terminal kinase and mediates inflammation-induced hypersensitivity.

Bas DB, Abdelmoaty S, Sandor K, Codeluppi S, Fitzsimmons B, Steinauer J, Hua XY, Yaksh TL, Svensson CI.

Eur J Pain. 2015 Feb;19(2):260-70. doi: 10.1002/ejp.544. Epub 2014 Jun 18.

34.

Olfactory exposure to males, including men, causes stress and related analgesia in rodents.

Sorge RE, Martin LJ, Isbester KA, Sotocinal SG, Rosen S, Tuttle AH, Wieskopf JS, Acland EL, Dokova A, Kadoura B, Leger P, Mapplebeck JC, McPhail M, Delaney A, Wigerblad G, Schumann AP, Quinn T, Frasnelli J, Svensson CI, Sternberg WF, Mogil JS.

Nat Methods. 2014 Jun;11(6):629-32. doi: 10.1038/nmeth.2935. Epub 2014 Apr 28.

PMID:
24776635
35.

Identification and quantification of neuropeptides in naïve mouse spinal cord using mass spectrometry reveals [des-Ser1]-cerebellin as a novel modulator of nociception.

Su J, Sandor K, Sköld K, Hökfelt T, Svensson CI, Kultima K.

J Neurochem. 2014 Jul;130(2):199-214. doi: 10.1111/jnc.12730. Epub 2014 May 7.

36.

Interleukin-6 secretion by astrocytes is dynamically regulated by PI3K-mTOR-calcium signaling.

Codeluppi S, Fernandez-Zafra T, Sandor K, Kjell J, Liu Q, Abrams M, Olson L, Gray NS, Svensson CI, Uhlén P.

PLoS One. 2014 Mar 25;9(3):e92649. doi: 10.1371/journal.pone.0092649. eCollection 2014.

37.

Spinal actions of lipoxin A4 and 17(R)-resolvin D1 attenuate inflammation-induced mechanical hypersensitivity and spinal TNF release.

Abdelmoaty S, Wigerblad G, Bas DB, Codeluppi S, Fernandez-Zafra T, El-Awady el-S, Moustafa Y, Abdelhamid Ael-D, Brodin E, Svensson CI.

PLoS One. 2013 Sep 24;8(9):e75543. doi: 10.1371/journal.pone.0075543. eCollection 2013.

38.

Rat substrains differ in the magnitude of spontaneous locomotor recovery and in the development of mechanical hypersensitivity after experimental spinal cord injury.

Kjell J, Sandor K, Josephson A, Svensson CI, Abrams MB.

J Neurotrauma. 2013 Nov 1;30(21):1805-11. doi: 10.1089/neu.2013.2998. Epub 2013 Sep 27.

39.

Distribution of transmembrane AMPA receptor regulatory protein (TARP) isoforms in the rat spinal cord.

Larsson M, Agalave N, Watanabe M, Svensson CI.

Neuroscience. 2013 Sep 17;248:180-93. doi: 10.1016/j.neuroscience.2013.05.060. Epub 2013 Jun 7.

PMID:
23751177
40.

Pentoxifylline and propentofylline prevent proliferation and activation of the mammalian target of rapamycin and mitogen activated protein kinase in cultured spinal astrocytes.

Norsted Gregory E, Delaney A, Abdelmoaty S, Bas DB, Codeluppi S, Wigerblad G, Svensson CI.

J Neurosci Res. 2013 Feb;91(2):300-12. doi: 10.1002/jnr.23144. Epub 2012 Nov 27.

PMID:
23184810
41.

Collagen antibody-induced arthritis evokes persistent pain with spinal glial involvement and transient prostaglandin dependency.

Bas DB, Su J, Sandor K, Agalave NM, Lundberg J, Codeluppi S, Baharpoor A, Nandakumar KS, Holmdahl R, Svensson CI.

Arthritis Rheum. 2012 Dec;64(12):3886-96. doi: 10.1002/art.37686.

42.

Peripheral inflammatory disease associated with centrally activated IL-1 system in humans and mice.

Lampa J, Westman M, Kadetoff D, Agréus AN, Le Maître E, Gillis-Haegerstrand C, Andersson M, Khademi M, Corr M, Christianson CA, Delaney A, Yaksh TL, Kosek E, Svensson CI.

Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12728-33. doi: 10.1073/pnas.1118748109. Epub 2012 Jul 16.

43.

K/BxN serum transfer arthritis as a model of inflammatory joint pain.

Christianson CA, Corr M, Yaksh TL, Svensson CI.

Methods Mol Biol. 2012;851:249-60. doi: 10.1007/978-1-61779-561-9_19.

44.

Spinal TLR4 mediates the transition to a persistent mechanical hypersensitivity after the resolution of inflammation in serum-transferred arthritis.

Christianson CA, Dumlao DS, Stokes JA, Dennis EA, Svensson CI, Corr M, Yaksh TL.

Pain. 2011 Dec;152(12):2881-91. doi: 10.1016/j.pain.2011.09.020. Epub 2011 Oct 21.

45.

Influence of rat substrain and growth conditions on the characteristics of primary cultures of adult rat spinal cord astrocytes.

Codeluppi S, Gregory EN, Kjell J, Wigerblad G, Olson L, Svensson CI.

J Neurosci Methods. 2011 Apr 15;197(1):118-27. doi: 10.1016/j.jneumeth.2011.02.011. Epub 2011 Feb 21.

PMID:
21345349
46.

Interleukin-6: a local pain trigger?

Svensson CI.

Arthritis Res Ther. 2010;12(5):145. doi: 10.1186/ar3138. Epub 2010 Oct 28.

47.

Characterization of the acute and persistent pain state present in K/BxN serum transfer arthritis.

Christianson CA, Corr M, Firestein GS, Mobargha A, Yaksh TL, Svensson CI.

Pain. 2010 Nov;151(2):394-403. doi: 10.1016/j.pain.2010.07.030. Epub 2010 Aug 23.

48.

Spinal glial TLR4-mediated nociception and production of prostaglandin E(2) and TNF.

Saito O, Svensson CI, Buczynski MW, Wegner K, Hua XY, Codeluppi S, Schaloske RH, Deems RA, Dennis EA, Yaksh TL.

Br J Pharmacol. 2010 Aug;160(7):1754-64. doi: 10.1111/j.1476-5381.2010.00811.x.

49.

Release of prostaglandin E(2) and nitric oxide from spinal microglia is dependent on activation of p38 mitogen-activated protein kinase.

Matsui T, Svensson CI, Hirata Y, Mizobata K, Hua XY, Yaksh TL.

Anesth Analg. 2010 Aug;111(2):554-60. doi: 10.1213/ANE.0b013e3181e3a2a2. Epub 2010 Jul 7.

PMID:
20610553
50.

Mammalian target of rapamycin in spinal cord neurons mediates hypersensitivity induced by peripheral inflammation.

Norsted Gregory E, Codeluppi S, Gregory JA, Steinauer J, Svensson CI.

Neuroscience. 2010 Sep 1;169(3):1392-402. doi: 10.1016/j.neuroscience.2010.05.067. Epub 2010 Jun 9.

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