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Items: 1 to 50 of 55

1.

Bacterial Peptide Display for the Selection of Novel Biotinylating Enzymes.

Granhøj J, Dimke H, Svenningsen P.

J Vis Exp. 2019 Oct 3;(152). doi: 10.3791/60266.

PMID:
31633696
2.

Nephrotic syndrome is associated with increased plasma K+ concentration, intestinal K+ losses and attenuated urinary K+ excretion - studies in rats and humans.

Ydegaard R, Svenningsen P, Bistrup C, Andersen RF, Stubbe J, Buhl KB, Marcussen N, Hinrichs GR, Iraqi H, Zamani R, Dimke H, Jensen BL.

Am J Physiol Renal Physiol. 2019 Sep 30. doi: 10.1152/ajprenal.00179.2019. [Epub ahead of print]

PMID:
31566427
3.

Dietary Na+ intake in healthy humans changes the urine extracellular vesicle prostasin abundance while vesicle excretion rate, NCC and ENaC are not altered.

Zachar R, Jensen BL, Svenningsen P.

Am J Physiol Renal Physiol. 2019 Sep 30. doi: 10.1152/ajprenal.00258.2019. [Epub ahead of print]

PMID:
31566425
4.

Urokinase-type plasminogen activator contributes to amiloride-sensitive sodium retention in nephrotic range glomerular proteinuria in mice.

Hinrichs GR, Weyer K, Friis UG, Svenningsen P, Lund IK, Nielsen R, Mollet G, Antignac C, Bistrup C, Jensen BL, Birn H.

Acta Physiol (Oxf). 2019 Aug 19:e13362. doi: 10.1111/apha.13362. [Epub ahead of print]

PMID:
31423748
5.

Urinary extracellular vesicles: Origin, role as intercellular messengers and biomarkers; efficient sorting and potential treatment options.

Svenningsen P, Sabaratnam R, Jensen BL.

Acta Physiol (Oxf). 2019 Jul 23:e13346. doi: 10.1111/apha.13346. [Epub ahead of print] Review.

PMID:
31334916
6.

In human nephrectomy specimens, the kidney level of tubular transport proteins does not correlate with their abundance in urinary extracellular vesicles.

Sabaratnam R, Geertsen L, Skjødt K, Højlund K, Dimke H, Lund L, Svenningsen P.

Am J Physiol Renal Physiol. 2019 Sep 1;317(3):F560-F571. doi: 10.1152/ajprenal.00242.2019. Epub 2019 Jun 26.

PMID:
31241991
7.

A bacterial display system for effective selection of protein-biotin ligase BirA variants with novel peptide specificity.

Granhøj J, Dimke H, Svenningsen P.

Sci Rep. 2019 Mar 11;9(1):4118. doi: 10.1038/s41598-019-40984-x.

8.

Effect of hospital-admission volume on outcomes following acute non-variceal upper gastrointestinal bleeding.

Schmidt MS, Preisler L, Fabricius R, Svenningsen P, Hillingsø J, Svendsen LB, Sillesen M.

Dan Med J. 2019 Feb;66(2). pii: A5531.

PMID:
30722826
9.

Aberrant neuronal differentiation is common in glioma but is associated neither with epileptic seizures nor with better survival.

Beier CP, Rasmussen T, Dahlrot RH, Tenstad HB, Aarø JS, Sørensen MF, Heimisdóttir SB, Sørensen MD, Svenningsen P, Riemenschneider MJ, Beier D, Kristensen BW.

Sci Rep. 2018 Oct 8;8(1):14965. doi: 10.1038/s41598-018-33282-5.

10.

The acute blood pressure-lowering effect of amiloride is independent of endothelial ENaC and eNOS in humans and mice.

Ydegaard R, Andersen H, Oxlund CS, Jacobsen IA, Hansen PBL, Jürgensen JF, Peluso AA, Vanhoutte PM, Staehr M, Svenningsen P, Jensen BL.

Acta Physiol (Oxf). 2019 Jan;225(1):e13189. doi: 10.1111/apha.13189. Epub 2018 Oct 11.

PMID:
30240139
11.

The effect of fluid resuscitation strategy on monocyte and T-cell surface markers.

Bonde A, Kirial R, Svenningsen P, Sillesen M.

J Surg Res. 2018 Oct;230:20-27. doi: 10.1016/j.jss.2018.04.029. Epub 2018 May 12.

PMID:
30100035
12.

H+-ATPase B1 subunit localizes to thick ascending limb and distal convoluted tubule of rodent and human kidney.

Frische S, Chambrey R, Trepiccione F, Zamani R, Marcussen N, Alexander RT, Skjødt K, Svenningsen P, Dimke H.

Am J Physiol Renal Physiol. 2018 Sep 1;315(3):F429-F444. doi: 10.1152/ajprenal.00539.2017. Epub 2018 Jul 11.

13.

Hydronephrosis is associated with elevated plasmin in urine in pediatric patients and rats and changes in NCC and γ-ENaC abundance in rat kidney.

Zachar R, Al-Mashhadi A, Dimke H, Svenningsen P, Jensen BL, Carlström M.

Am J Physiol Renal Physiol. 2018 Sep 1;315(3):F547-F557. doi: 10.1152/ajprenal.00635.2017. Epub 2018 May 16.

14.

Albuminuria in kidney transplant recipients is associated with increased urinary serine proteases and activation of the epithelial sodium channel.

Hinrichs GR, Michelsen JS, Zachar R, Friis UG, Svenningsen P, Birn H, Bistrup C, Jensen BL.

Am J Physiol Renal Physiol. 2018 Jul 1;315(1):F151-F160. doi: 10.1152/ajprenal.00545.2017. Epub 2018 Jan 24.

15.

Self-evaluated competence in trauma reception.

Steinthorsdottir KJ, Svenningsen P, Fabricius R, Svendsen LB, Hillingsø J, Sillesen M.

Dan Med J. 2017 Nov;64(11). pii: A5420.

PMID:
29115207
16.

Enhanced Recovery After Surgery (ERAS) - The Evidence in Geriatric Emergency Surgery: A Systematic Review.

Paduraru M, Ponchietti L, Casas IM, Svenningsen P, Pereira J, Landaluce-Olavarria A, Font RF, Miguel IP, Ugarte-Sierra B.

Chirurgia (Bucur). 2017 Sept-Oct;112(5):546-557. doi: 10.21614/chirurgia.112.5.546. Review.

17.

The effect of resuscitation strategy on the longitudinal immuno-inflammatory response to blunt trauma.

Bonde A, Nordestgaard AT, Kirial R, Svenningsen P, Sillesen M.

Injury. 2017 Dec;48(12):2670-2674. doi: 10.1016/j.injury.2017.09.026. Epub 2017 Sep 28.

PMID:
28988067
18.

Physiology and pathophysiology of the plasminogen system in the kidney.

Svenningsen P, Hinrichs GR, Zachar R, Ydegaard R, Jensen BL.

Pflugers Arch. 2017 Nov;469(11):1415-1423. doi: 10.1007/s00424-017-2014-y. Epub 2017 Jun 27. Review.

PMID:
28656379
19.

Expression of transcellular and paracellular calcium and magnesium transport proteins in renal and intestinal epithelia during lactation.

Beggs MR, Appel I, Svenningsen P, Skjødt K, Alexander RT, Dimke H.

Am J Physiol Renal Physiol. 2017 Sep 1;313(3):F629-F640. doi: 10.1152/ajprenal.00680.2016. Epub 2017 May 24.

20.

Enhanced Recovery after Emergency Surgery: A Systematic Review.

Paduraru M, Ponchietti L, Casas IM, Svenningsen P, Zago M.

Bull Emerg Trauma. 2017 Apr;5(2):70-78. Review.

21.

Urine exosomes from healthy and hypertensive pregnancies display elevated level of α-subunit and cleaved α- and γ-subunits of the epithelial sodium channel-ENaC.

Nielsen MR, Frederiksen-Møller B, Zachar R, Jørgensen JS, Hansen MR, Ydegaard R, Svenningsen P, Buhl K, Jensen BL.

Pflugers Arch. 2017 Sep;469(9):1107-1119. doi: 10.1007/s00424-017-1977-z. Epub 2017 Apr 12.

PMID:
28405801
22.

Albuminuria is associated with an increased prostasin in urine while aldosterone has no direct effect on urine and kidney tissue abundance of prostasin.

Oxlund C, Kurt B, Schwarzensteiner I, Hansen MR, Stæhr M, Svenningsen P, Jacobsen IA, Hansen PB, Thuesen AD, Toft A, Hinrichs GR, Bistrup C, Jensen BL.

Pflugers Arch. 2017 Jun;469(5-6):655-667. doi: 10.1007/s00424-017-1938-6. Epub 2017 Feb 24.

PMID:
28233126
23.

National variation in transfusion strategies in patients with upper gastrointestinal bleeding.

Steinthorsdottir KJ, Svenningsen P, Fabricius R, Hillingsøe J, Svendsen LB, Sillesen M.

Dan Med J. 2016 Nov;63(11). pii: A5296.

PMID:
27808036
24.

Biosensor cell assay for measuring real-time aldosterone-induced release of histamine from mesenteric arteries.

Dalgaard EG, Andersen K, Svenningsen P, Hansen PB.

Acta Physiol (Oxf). 2017 Jan;219(1):219-226. doi: 10.1111/apha.12680. Epub 2016 Apr 5.

PMID:
26990768
25.

The genetic background affects the vascular response in T-type calcium channels 3.2 deficient mice.

Svenningsen P, Hansen PB.

Acta Physiol (Oxf). 2016 Jun;217(2):101-2. doi: 10.1111/apha.12655. Epub 2016 Feb 5. No abstract available.

PMID:
26800239
26.

Effect of Transfusion Strategy in Acute Non-variceal Upper Gastrointestinal Bleeding: A Nationwide Study of 5861 Hospital Admissions in Denmark.

Fabricius R, Svenningsen P, Hillingsø J, Svendsen LB, Sillesen M.

World J Surg. 2016 May;40(5):1129-36. doi: 10.1007/s00268-015-3370-4.

PMID:
26675926
27.

Histone deactylase gene expression profiles are associated with outcomes in blunt trauma patients.

Sillesen M, Bambakidis T, Dekker SE, Fabricius R, Svenningsen P, Bruhn PJ, Svendsen LB, Hillingsø J, Alam HB.

J Trauma Acute Care Surg. 2016 Jan;80(1):26-32; discussion 32-3. doi: 10.1097/TA.0000000000000896.

PMID:
26517778
28.

Stressed podocytes - Bestrophin-3 is not just Bestrophin-3.

Svenningsen P.

Acta Physiol (Oxf). 2015 Aug;214(4):430-1. doi: 10.1111/apha.12539. Epub 2015 Jun 16. No abstract available.

PMID:
26052975
29.

Aberrant glomerular filtration of urokinase-type plasminogen activator in nephrotic syndrome leads to amiloride-sensitive plasminogen activation in urine.

Stæhr M, Buhl KB, Andersen RF, Svenningsen P, Nielsen F, Hinrichs GR, Bistrup C, Jensen BL.

Am J Physiol Renal Physiol. 2015 Aug 1;309(3):F235-41. doi: 10.1152/ajprenal.00138.2015. Epub 2015 May 13.

30.

Percutaneous yttrium aluminum garnet-laser lithotripsy of intrahepatic stones and casts after liver transplantation.

Schlesinger NH, Svenningsen P, Frevert S, Wettergren A, Hillingsø J.

Liver Transpl. 2015 Jun;21(6):831-7. doi: 10.1002/lt.24120. Epub 2015 May 6.

31.

Diabetic nephropathy is associated with increased urine excretion of proteases plasmin, prostasin and urokinase and activation of amiloride-sensitive current in collecting duct cells.

Andersen H, Friis UG, Hansen PB, Svenningsen P, Henriksen JE, Jensen BL.

Nephrol Dial Transplant. 2015 May;30(5):781-9. doi: 10.1093/ndt/gfu402. Epub 2015 Jan 20.

PMID:
25609736
32.

Urinary serine proteases and activation of ENaC in kidney--implications for physiological renal salt handling and hypertensive disorders with albuminuria.

Svenningsen P, Andersen H, Nielsen LH, Jensen BL.

Pflugers Arch. 2015 Mar;467(3):531-42. doi: 10.1007/s00424-014-1661-5. Epub 2014 Dec 9. Review.

PMID:
25482671
33.

Increased mortality in the elderly after emergency abdominal surgery.

Svenningsen P, Manoharan T, Foss NB, Lauritsen ML, Bay-Nielsen M.

Dan Med J. 2014 Jul;61(7):A4876.

PMID:
25123123
34.

The epithelial sodium channel γ-subunit is processed proteolytically in human kidney.

Zachar RM, Skjødt K, Marcussen N, Walter S, Toft A, Nielsen MR, Jensen BL, Svenningsen P.

J Am Soc Nephrol. 2015 Jan;26(1):95-106. doi: 10.1681/ASN.2013111173. Epub 2014 Jul 24.

35.

TMEM16A is a Ca(2+) -activated Cl(-) channel expressed in the renal collecting duct.

Svenningsen P, Nielsen MR, Marcussen N, Walter S, Jensen BL.

Acta Physiol (Oxf). 2014 Oct;212(2):166-74. doi: 10.1111/apha.12323. Epub 2014 Jun 26.

PMID:
24913262
36.

Plasmin in urine from patients with type 2 diabetes and treatment-resistant hypertension activates ENaC in vitro.

Buhl KB, Oxlund CS, Friis UG, Svenningsen P, Bistrup C, Jacobsen IA, Jensen BL.

J Hypertens. 2014 Aug;32(8):1672-7; discussion 1677. doi: 10.1097/HJH.0000000000000216.

PMID:
24805959
37.

T-type Ca(2+) channels facilitate NO-formation, vasodilatation and NO-mediated modulation of blood pressure.

Svenningsen P, Andersen K, Thuesen AD, Shin HS, Vanhoutte PM, Skøtt O, Jensen BL, Hill C, Hansen PB.

Pflugers Arch. 2014 Dec;466(12):2205-14. doi: 10.1007/s00424-014-1492-4. Epub 2014 Mar 14.

PMID:
24627154
38.

ATP releasing connexin 30 hemichannels mediate flow-induced calcium signaling in the collecting duct.

Svenningsen P, Burford JL, Peti-Peterdi J.

Front Physiol. 2013 Oct 16;4:292. doi: 10.3389/fphys.2013.00292. eCollection 2013.

39.

Remission of nephrotic syndrome diminishes urinary plasmin content and abolishes activation of ENaC.

Andersen RF, Buhl KB, Jensen BL, Svenningsen P, Friis UG, Jespersen B, Rittig S.

Pediatr Nephrol. 2013 Aug;28(8):1227-34. doi: 10.1007/s00467-013-2439-2. Epub 2013 Mar 16.

PMID:
23503750
40.

Histamine-dependent prolongation by aldosterone of vasoconstriction in isolated small mesenteric arteries of the mouse.

Schjerning J, Uhrenholt TR, Svenningsen P, Vanhoutte PM, Skøtt O, Jensen BL, Hansen PB.

Am J Physiol Heart Circ Physiol. 2013 Apr 15;304(8):H1094-102. doi: 10.1152/ajpheart.00524.2012. Epub 2013 Feb 8.

41.

Mechanisms of renal NaCl retention in proteinuric disease.

Svenningsen P, Friis UG, Versland JB, Buhl KB, Møller Frederiksen B, Andersen H, Zachar RM, Bistrup C, Skøtt O, Jørgensen JS, Andersen RF, Jensen BL.

Acta Physiol (Oxf). 2013 Mar;207(3):536-45. doi: 10.1111/apha.12047. Epub 2013 Jan 7. Review.

PMID:
23216619
42.

Urinary plasmin activates collecting duct ENaC current in preeclampsia.

Buhl KB, Friis UG, Svenningsen P, Gulaveerasingam A, Ovesen P, Frederiksen-Møller B, Jespersen B, Bistrup C, Jensen BL.

Hypertension. 2012 Nov;60(5):1346-51. doi: 10.1161/HYPERTENSIONAHA.112.198879. Epub 2012 Sep 17.

PMID:
22987920
43.

Regulation of renin secretion by renal juxtaglomerular cells.

Friis UG, Madsen K, Stubbe J, Hansen PB, Svenningsen P, Bie P, Skøtt O, Jensen BL.

Pflugers Arch. 2013 Jan;465(1):25-37. doi: 10.1007/s00424-012-1126-7. Epub 2012 Jun 26. Review.

PMID:
22733355
44.

Physiological regulation of epithelial sodium channel by proteolysis.

Svenningsen P, Friis UG, Bistrup C, Buhl KB, Jensen BL, Skøtt O.

Curr Opin Nephrol Hypertens. 2011 Sep;20(5):529-33. doi: 10.1097/MNH.0b013e328348bcc7. Review.

PMID:
21670672
45.

Proteinuric diseases with sodium retention: Is plasmin the link?

Svenningsen P, Skøtt O, Jensen BL.

Clin Exp Pharmacol Physiol. 2012 Jan;39(1):117-24. doi: 10.1111/j.1440-1681.2011.05524.x. Review.

PMID:
21466573
46.

Chronic treatment with vitamin D lowers arterial blood pressure and reduces endothelium-dependent contractions in the aorta of the spontaneously hypertensive rat.

Wong MS, Delansorne R, Man RY, Svenningsen P, Vanhoutte PM.

Am J Physiol Heart Circ Physiol. 2010 Oct;299(4):H1226-34. doi: 10.1152/ajpheart.00288.2010. Epub 2010 Aug 6.

47.

Apical serine protease activity is necessary for assembly of a high-resistance renal collecting duct epithelium.

Steensgaard M, Svenningsen P, Tinning AR, Nielsen TD, Jørgensen F, Kjaersgaard G, Madsen K, Jensen BL.

Acta Physiol (Oxf). 2010 Dec;200(4):347-59. doi: 10.1111/j.1748-1716.2010.02170.x.

PMID:
20645929
48.

Laparoscopic reversal of Hartmann's procedure.

Svenningsen PO, Bulut O, Jess P.

Dan Med Bull. 2010 Jun;57(6):A4149.

PMID:
20515601
49.

Prostasin-dependent activation of epithelial Na+ channels by low plasmin concentrations.

Svenningsen P, Uhrenholt TR, Palarasah Y, Skjødt K, Jensen BL, Skøtt O.

Am J Physiol Regul Integr Comp Physiol. 2009 Dec;297(6):R1733-41. doi: 10.1152/ajpregu.00321.2009. Epub 2009 Sep 30.

50.

Hypotonicity-induced Renin exocytosis from juxtaglomerular cells requires aquaporin-1 and cyclooxygenase-2.

Friis UG, Madsen K, Svenningsen P, Hansen PB, Gulaveerasingam A, Jørgensen F, Aalkjaer C, Skøtt O, Jensen BL.

J Am Soc Nephrol. 2009 Oct;20(10):2154-61. doi: 10.1681/ASN.2008090944. Epub 2009 Jul 23.

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