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Items: 1 to 50 of 358

1.

Role of antigen specific T and B cells in systemic and mucosal immune responses in ETEC and Shigella infections, and their potential to serve as correlates of protection in vaccine development.

Mani S, Toapanta FR, McArthur MA, Qadri F, Svennerholm AM, Devriendt B, Phalipon A, Cohen D, Sztein MB.

Vaccine. 2019 Aug 7;37(34):4787-4793. doi: 10.1016/j.vaccine.2019.03.040. Epub 2019 Jun 20.

PMID:
31230883
2.

Colonization factors among enterotoxigenic Escherichia coli isolates from children with moderate-to-severe diarrhea and from matched controls in the Global Enteric Multicenter Study (GEMS).

Vidal RM, Muhsen K, Tennant SM, Svennerholm AM, Sow SO, Sur D, Zaidi AKM, Faruque ASG, Saha D, Adegbola R, Hossain MJ, Alonso PL, Breiman RF, Bassat Q, Tamboura B, Sanogo D, Onwuchekwa U, Manna B, Ramamurthy T, Kanungo S, Ahmed S, Qureshi S, Quadri F, Hossain A, Das SK, Antonio M, Mandomando I, Nhampossa T, Acácio S, Omore R, Ochieng JB, Oundo JO, Mintz ED, O'Reilly CE, Berkeley LY, Livio S, Panchalingam S, Nasrin D, Farag TH, Wu Y, Sommerfelt H, Robins-Browne RM, Del Canto F, Hazen TH, Rasko DA, Kotloff KL, Nataro JP, Levine MM.

PLoS Negl Trop Dis. 2019 Jan 4;13(1):e0007037. doi: 10.1371/journal.pntd.0007037. eCollection 2019 Jan.

3.

Evaluation of the safety and immunogenicity of the oral inactivated multivalent enterotoxigenic Escherichia coli vaccine ETVAX in Bangladeshi adults in a double-blind, randomized, placebo-controlled Phase I trial using electrochemiluminescence and ELISA assays for immunogenicity analyses.

Akhtar M, Chowdhury MI, Bhuiyan TR, Kaim J, Ahmed T, Rafique TA, Khan A, Rahman SIA, Khanam F, Begum YA, Sharif MZ, Islam LN, Carlin N, Maier N, Fix A, Wierzba TF, Walker RI, Bourgeois AL, Svennerholm AM, Qadri F, Lundgren A.

Vaccine. 2019 Sep 3;37(37):5645-5656. doi: 10.1016/j.vaccine.2018.11.040. Epub 2018 Nov 22.

4.

Glyco-engineered cell line and computational docking studies reveals enterotoxigenic Escherichia coli CFA/I fimbriae bind to Lewis a glycans.

Mottram L, Liu J, Chavan S, Tobias J, Svennerholm AM, Holgersson J.

Sci Rep. 2018 Jul 26;8(1):11250. doi: 10.1038/s41598-018-29258-0.

5.

Publisher Correction: Identification and characterization of the novel colonization factor CS30 based on whole genome sequencing in enterotoxigenic Escherichia coli (ETEC).

von Mentzer A, Tobias J, Wiklund G, Nordqvist S, Aslett M, Dougan G, Sjöling Å, Svennerholm AM.

Sci Rep. 2018 Apr 12;8(1):6004. doi: 10.1038/s41598-018-23723-6.

6.

Author Correction: FUT2 non-secretor status is associated with altered susceptibility to symptomatic enterotoxigenic Escherichia coli infection in Bangladeshis.

Mottram L, Wiklund G, Larson G, Qadri F, Svennerholm AM.

Sci Rep. 2018 Apr 11;8(1):6058. doi: 10.1038/s41598-018-22786-9.

7.

Assessing antigen specific HLA-DR+ antibody secreting cell (DR+ASC) responses in whole blood in enteric infections using an ELISPOT technique.

Bhuiyan TR, Hoq MR, Nishat NS, Al Mahbuba D, Rashu R, Islam K, Hossain L, Harris JB, Ryan ET, Calderwood SB, Svennerholm AM, Qadri F.

Microbes Infect. 2018 Feb;20(2):122-129. doi: 10.1016/j.micinf.2017.10.005. Epub 2017 Nov 8.

8.

Identification and characterization of the novel colonization factor CS30 based on whole genome sequencing in enterotoxigenic Escherichia coli (ETEC).

von Mentzer A, Tobias J, Wiklund G, Nordqvist S, Aslett M, Dougan G, Sjöling Å, Svennerholm AM.

Sci Rep. 2017 Oct 2;7(1):12514. doi: 10.1038/s41598-017-12743-3. Erratum in: Sci Rep. 2018 Apr 12;8(1):6004.

9.

FUT2 non-secretor status is associated with altered susceptibility to symptomatic enterotoxigenic Escherichia coli infection in Bangladeshis.

Mottram L, Wiklund G, Larson G, Qadri F, Svennerholm AM.

Sci Rep. 2017 Sep 6;7(1):10649. doi: 10.1038/s41598-017-10854-5. Erratum in: Sci Rep. 2018 Apr 11;8(1):6058.

10.

Gastric expression of IL-17A and IFNγ in Helicobacter pylori infected individuals is related to symptoms.

Adamsson J, Ottsjö LS, Lundin SB, Svennerholm AM, Raghavan S.

Cytokine. 2017 Nov;99:30-34. doi: 10.1016/j.cyto.2017.06.013. Epub 2017 Jul 3.

PMID:
28683359
11.

Cross-reactivity and avidity of antibody responses induced in humans by the oral inactivated multivalent enterotoxigenicEscherichia coli (ETEC) vaccine ETVAX.

Leach S, Lundgren A, Carlin N, Löfstrand M, Svennerholm AM.

Vaccine. 2017 Jul 13;35(32):3966-3973. doi: 10.1016/j.vaccine.2017.06.006. Epub 2017 Jun 16.

PMID:
28625524
12.

Surface expression of Helicobacter pylori HpaA adhesion antigen on Vibrio cholerae, enhanced by co-expressed enterotoxigenic Escherichia coli fimbrial antigens.

Tobias J, Lebens M, Wai SN, Holmgren J, Svennerholm AM.

Microb Pathog. 2017 Apr;105:177-184. doi: 10.1016/j.micpath.2017.02.021. Epub 2017 Feb 17.

PMID:
28215587
13.

Kinetics of antibody-secreting cell and fecal IgA responses after oral cholera vaccination in different age groups in a cholera endemic country.

Akhtar M, Qadri F, Bhuiyan TR, Akter S, Rafique TA, Khan A, Islam LN, Saha A, Svennerholm AM, Lundgren A.

Vaccine. 2017 Jan 5;35(2):321-328. doi: 10.1016/j.vaccine.2016.11.055.

PMID:
27916412
14.

Identification of new heat-stable (STa) enterotoxin allele variants produced by human enterotoxigenic Escherichia coli (ETEC).

Joffré E, von Mentzer A, Svennerholm AM, Sjöling Å.

Int J Med Microbiol. 2016 Nov;306(7):586-594. doi: 10.1016/j.ijmm.2016.05.016. Epub 2016 Jun 15.

15.

Resistance Pattern and Molecular Characterization of Enterotoxigenic Escherichia coli (ETEC) Strains Isolated in Bangladesh.

Begum YA, Talukder KA, Azmi IJ, Shahnaij M, Sheikh A, Sharmin S, Svennerholm AM, Qadri F.

PLoS One. 2016 Jul 18;11(7):e0157415. doi: 10.1371/journal.pone.0157415. eCollection 2016.

16.

[The role of antibacterial substances in the development of resistance. A broad approach is required to limit antibiotic resistance].

Larsson J, Svennerholm AM.

Lakartidningen. 2016 Jul 11;113. pii: D44E. Swedish. No abstract available.

17.

Induction of long term mucosal immunological memory in humans by an oral inactivated multivalent enterotoxigenic Escherichia coli vaccine.

Lundgren A, Jertborn M, Svennerholm AM.

Vaccine. 2016 Jun 8;34(27):3132-3140. doi: 10.1016/j.vaccine.2016.04.055. Epub 2016 Apr 28.

18.

Stability of the Encoding Plasmids and Surface Expression of CS6 Differs in Enterotoxigenic Escherichia coli (ETEC) Encoding Different Heat-Stable (ST) Enterotoxins (STh and STp).

Tobias J, Von Mentzer A, Loayza Frykberg P, Aslett M, Page AJ, Sjöling Å, Svennerholm AM.

PLoS One. 2016 Apr 7;11(4):e0152899. doi: 10.1371/journal.pone.0152899. eCollection 2016.

19.

Enumeration of Gut-Homing β7-Positive, Pathogen-Specific Antibody-Secreting Cells in Whole Blood from Enterotoxigenic Escherichia coli- and Vibrio cholerae-Infected Patients, Determined Using an Enzyme-Linked Immunosorbent Spot Assay Technique.

Bhuiyan TR, Hoq MR, Nishat NS, Al Mahbuba D, Rashu R, Islam K, Hossain L, Dey A, Harris JB, Ryan ET, Calderwood SB, Svennerholm AM, Qadri F.

Clin Vaccine Immunol. 2015 Oct 28;23(1):27-36. doi: 10.1128/CVI.00526-15. Print 2016 Jan.

20.

Implications of enterotoxigenic Escherichia coli genomics for vaccine development.

Sjöling Å, von Mentzer A, Svennerholm AM.

Expert Rev Vaccines. 2015 Apr;14(4):551-60. doi: 10.1586/14760584.2015.996553. Epub 2014 Dec 26. Review.

PMID:
25540974
21.

Safety and immunogenicity of an improved oral inactivated multivalent enterotoxigenic Escherichia coli (ETEC) vaccine administered alone and together with dmLT adjuvant in a double-blind, randomized, placebo-controlled Phase I study.

Lundgren A, Bourgeois L, Carlin N, Clements J, Gustafsson B, Hartford M, Holmgren J, Petzold M, Walker R, Svennerholm AM.

Vaccine. 2014 Dec 12;32(52):7077-84. doi: 10.1016/j.vaccine.2014.10.069. Epub 2014 Nov 5.

22.

Allele variants of enterotoxigenic Escherichia coli heat-labile toxin are globally transmitted and associated with colonization factors.

Joffré E, von Mentzer A, Abd El Ghany M, Oezguen N, Savidge T, Dougan G, Svennerholm AM, Sjöling Å.

J Bacteriol. 2015 Jan;197(2):392-403. doi: 10.1128/JB.02050-14. Epub 2014 Nov 17.

23.

Identification of enterotoxigenic Escherichia coli (ETEC) clades with long-term global distribution.

von Mentzer A, Connor TR, Wieler LH, Semmler T, Iguchi A, Thomson NR, Rasko DA, Joffre E, Corander J, Pickard D, Wiklund G, Svennerholm AM, Sjöling Å, Dougan G.

Nat Genet. 2014 Dec;46(12):1321-6. doi: 10.1038/ng.3145. Epub 2014 Nov 10.

PMID:
25383970
24.

A comparison of seasonal variations in rotavirus antibodies in the breast milk of Swedish and Bangladeshi mothers.

Novak D, Svennerholm AM.

Acta Paediatr. 2015 Mar;104(3):247-51. doi: 10.1111/apa.12841. Epub 2014 Nov 17.

PMID:
25355609
25.

Toxins and virulence factors of enterotoxigenic Escherichia coli associated with strains isolated from indigenous children and international visitors to a rural community in Guatemala.

Torres OR, González W, Lemus O, Pratdesaba RA, Matute JA, Wiklund G, Sack DA, Bourgeois AL, Svennerholm AM.

Epidemiol Infect. 2015 Jun;143(8):1662-71. doi: 10.1017/S0950268814002295. Epub 2014 Sep 19.

26.

Shift in phenotypic characteristics of enterotoxigenic Escherichia coli (ETEC) isolated from diarrheal patients in Bangladesh.

Begum YA, Baby NI, Faruque AS, Jahan N, Cravioto A, Svennerholm AM, Qadri F.

PLoS Negl Trop Dis. 2014 Jul 17;8(7):e3031. doi: 10.1371/journal.pntd.0003031. eCollection 2014 Jul.

27.

Response on letter by Arya et al.: "evaluation of immune responses to an oral typhoid vaccine, Ty21a, in children from 2 to 5 years of age in Bangladesh.".

Bhuiyan TR, Choudhury FK, Khanam F, Saha A, Sayeed MA, Salma U, Qadri F, Lundgren A, Svennerholm AM, Sack DA.

Vaccine. 2014 Jul 7;32(32):4014. doi: 10.1016/j.vaccine.2014.03.099. Epub 2014 May 14. No abstract available.

PMID:
24837778
28.

Diarrhea burden due to natural infection with enterotoxigenic Escherichia coli in a birth cohort in a rural Egyptian community.

Mansour A, Shaheen HI, Amine M, Hassan K, Sanders JW, Riddle MS, Armstrong AW, Svennerholm AM, Sebeny PJ, Klena JD, Young SY, Frenck RW.

J Clin Microbiol. 2014 Jul;52(7):2595-603. doi: 10.1128/JCM.00215-14. Epub 2014 May 14.

29.

Antigen-specific memory B-cell responses to enterotoxigenic Escherichia coli infection in Bangladeshi adults.

Alam MM, Aktar A, Afrin S, Rahman MA, Aktar S, Uddin T, Rahman MA, Al Mahbuba D, Chowdhury F, Khan AI, Bhuiyan TR, Begum YA, Ryan ET, Calderwood SB, Svennerholm AM, Qadri F.

PLoS Negl Trop Dis. 2014 Apr 24;8(4):e2822. doi: 10.1371/journal.pntd.0002822. eCollection 2014 Apr.

30.

Pathogenicity and phenotypic characterization of enterotoxigenic Escherichia coli isolates from a birth cohort of children in rural Egypt.

Mansour A, Shaheen HI, Amine M, Hassan K, Sanders JW, Riddle MS, Armstrong AW, Svennerholm AM, Sebeny PJ, Klena JD, Young SY, Frenck RW Jr.

J Clin Microbiol. 2014 Feb;52(2):587-91. doi: 10.1128/JCM.01639-13. Epub 2013 Dec 11.

31.

Evaluation of immune responses to an oral typhoid vaccine, Ty21a, in children from 2 to 5 years of age in Bangladesh.

Bhuiyan TR, Choudhury FK, Khanam F, Saha A, Sayeed MA, Salma U, Lundgren A, Sack DA, Svennerholm AM, Qadri F.

Vaccine. 2014 Feb 19;32(9):1055-60. doi: 10.1016/j.vaccine.2014.01.001. Epub 2014 Jan 15.

PMID:
24440210
32.

Prevalence, seasonality and severity of disease caused by pathogenic Escherichia coli in children with diarrhoea in Bolivia.

Gonzales L, Joffre E, Rivera R, Sjöling Å, Svennerholm AM, Iñiguez V.

J Med Microbiol. 2013 Nov;62(Pt 11):1697-706. doi: 10.1099/jmm.0.060798-0. Epub 2013 Jul 12.

PMID:
23851188
33.

Different kinetics of circulating antibody-secreting cell responses after primary and booster oral immunizations: a tool for assessing immunological memory.

Leach S, Lundgren A, Svennerholm AM.

Vaccine. 2013 Jun 26;31(30):3035-8. doi: 10.1016/j.vaccine.2013.04.066. Epub 2013 May 10.

PMID:
23664997
34.

Development and preclinical evaluation of safety and immunogenicity of an oral ETEC vaccine containing inactivated E. coli bacteria overexpressing colonization factors CFA/I, CS3, CS5 and CS6 combined with a hybrid LT/CT B subunit antigen, administered alone and together with dmLT adjuvant.

Holmgren J, Bourgeois L, Carlin N, Clements J, Gustafsson B, Lundgren A, Nygren E, Tobias J, Walker R, Svennerholm AM.

Vaccine. 2013 May 7;31(20):2457-64. doi: 10.1016/j.vaccine.2013.03.027. Epub 2013 Mar 27.

35.

Molecular characterization of enterotoxigenic Escherichia coli isolates recovered from children with diarrhea during a 4-year period (2007 to 2010) in Bolivia.

Gonzales L, Sanchez S, Zambrana S, Iñiguez V, Wiklund G, Svennerholm AM, Sjöling A.

J Clin Microbiol. 2013 Apr;51(4):1219-25. doi: 10.1128/JCM.02971-12. Epub 2013 Feb 6.

36.

Clinical trial to evaluate safety and immunogenicity of an oral inactivated enterotoxigenic Escherichia coli prototype vaccine containing CFA/I overexpressing bacteria and recombinantly produced LTB/CTB hybrid protein.

Lundgren A, Leach S, Tobias J, Carlin N, Gustafsson B, Jertborn M, Bourgeois L, Walker R, Holmgren J, Svennerholm AM.

Vaccine. 2013 Feb 6;31(8):1163-70. doi: 10.1016/j.vaccine.2012.12.063. Epub 2013 Jan 7.

PMID:
23306362
37.

Vaccine specific immune response to an inactivated oral cholera vaccine and EPI vaccines in a high and low arsenic area in Bangladeshi children.

Saha A, Chowdhury MI, Nazim M, Alam MM, Ahmed T, Hossain MB, Hore SK, Sultana GN, Svennerholm AM, Qadri F.

Vaccine. 2013 Jan 11;31(4):647-52. doi: 10.1016/j.vaccine.2012.11.049. Epub 2012 Nov 28.

PMID:
23200936
38.

Diagnostic microbiologic methods in the GEMS-1 case/control study.

Panchalingam S, Antonio M, Hossain A, Mandomando I, Ochieng B, Oundo J, Ramamurthy T, Tamboura B, Zaidi AK, Petri W, Houpt E, Murray P, Prado V, Vidal R, Steele D, Strockbine N, Sansonetti P, Glass RI, Robins-Browne RM, Tauschek M, Svennerholm AM, Berkeley LY, Kotloff K, Levine MM, Nataro JP.

Clin Infect Dis. 2012 Dec;55 Suppl 4:S294-302. doi: 10.1093/cid/cis754. Erratum in: Clin Infect Dis. 2013 Jun;56(12):1851. Berkeley, Lynette Y [added].

39.

Immune responses and protection in children in developing countries induced by oral vaccines.

Qadri F, Bhuiyan TR, Sack DA, Svennerholm AM.

Vaccine. 2013 Jan 7;31(3):452-60. doi: 10.1016/j.vaccine.2012.11.012. Epub 2012 Nov 12. Review.

PMID:
23153448
40.

Immune responses against Helicobacter pylori in gastric cancer patients and in risk groups for gastric cancer.

Adamsson J, Lundin SB, Hansson LE, Sjövall H, Svennerholm AM.

Helicobacter. 2013 Feb;18(1):73-82. doi: 10.1111/j.1523-5378.2012.00991.x. Epub 2012 Sep 21.

PMID:
23067268
41.

Vaccines against mucosal infections.

Holmgren J, Svennerholm AM.

Curr Opin Immunol. 2012 Jun;24(3):343-53. doi: 10.1016/j.coi.2012.03.014. Epub 2012 May 12. Review.

42.

Expression of colonization factor CS5 of enterotoxigenic Escherichia coli (ETEC) is enhanced in vivo and by the bile component Na glycocholate hydrate.

Nicklasson M, Sjöling Å, von Mentzer A, Qadri F, Svennerholm AM.

PLoS One. 2012;7(4):e35827. doi: 10.1371/journal.pone.0035827. Epub 2012 Apr 30.

43.

Recent progress toward an enterotoxigenic Escherichia coli vaccine.

Svennerholm AM, Lundgren A.

Expert Rev Vaccines. 2012 Apr;11(4):495-507. doi: 10.1586/erv.12.12.

PMID:
22551034
44.

Strategies to overexpress enterotoxigenic Escherichia coli (ETEC) colonization factors for the construction of oral whole-cell inactivated ETEC vaccine candidates.

Tobias J, Svennerholm AM.

Appl Microbiol Biotechnol. 2012 Mar;93(6):2291-300. doi: 10.1007/s00253-012-3930-6. Epub 2012 Feb 16. Review.

PMID:
22350259
45.

Construction of a non-toxigenic Escherichia coli oral vaccine strain expressing large amounts of CS6 and inducing strong intestinal and serum anti-CS6 antibody responses in mice.

Tobias J, Svennerholm AM, Carlin NI, Lebens M, Holmgren J.

Vaccine. 2011 Nov 8;29(48):8863-9. doi: 10.1016/j.vaccine.2011.09.096. Epub 2011 Oct 6.

PMID:
21983363
46.

Refinement of a human challenge model for evaluation of enterotoxigenic Escherichia coli vaccines.

Harro C, Chakraborty S, Feller A, DeNearing B, Cage A, Ram M, Lundgren A, Svennerholm AM, Bourgeois AL, Walker RI, Sack DA.

Clin Vaccine Immunol. 2011 Oct;18(10):1719-27. doi: 10.1128/CVI.05194-11. Epub 2011 Aug 18.

47.

Enterotoxins, colonization factors, serotypes and antimicrobial resistance of enterotoxigenic Escherichia coli (ETEC) strains isolated from hospitalized children with diarrhea in Bolivia.

Rodas C, Mamani R, Blanco J, Blanco JE, Wiklund G, Svennerholm AM, Sjöling A, Iniguez V.

Braz J Infect Dis. 2011 Mar-Apr;15(2):132-7.

48.

Impact of rapid urbanization on the rates of infection by Vibrio cholerae O1 and enterotoxigenic Escherichia coli in Dhaka, Bangladesh.

Chowdhury F, Rahman MA, Begum YA, Khan AI, Faruque AS, Saha NC, Baby NI, Malek MA, Kumar AR, Svennerholm AM, Pietroni M, Cravioto A, Qadri F.

PLoS Negl Trop Dis. 2011 Apr 5;5(4):e999. doi: 10.1371/journal.pntd.0000999.

49.

From cholera to enterotoxigenic Escherichia coli (ETEC) vaccine development.

Svennerholm AM.

Indian J Med Res. 2011 Feb;133:188-96. Review.

50.

Impaired IFN-γ production after stimulation with bacterial components by natural killer cells from gastric cancer patients.

Lindgren Å, Yun CH, Sjöling Å, Berggren C, Sun JB, Jonsson E, Holmgren J, Svennerholm AM, Lundin SB.

Exp Cell Res. 2011 Apr 1;317(6):849-58. doi: 10.1016/j.yexcr.2011.01.006. Epub 2011 Jan 19.

PMID:
21255568

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