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Items: 1 to 50 of 193

1.

Huntington's Disease Patient-Derived Astrocytes Display Electrophysiological Impairments and Reduced Neuronal Support.

Garcia VJ, Rushton DJ, Tom CM, Allen ND, Kemp PJ, Svendsen CN, Mattis VB.

Front Neurosci. 2019 Jun 28;13:669. doi: 10.3389/fnins.2019.00669. eCollection 2019.

2.

Human iPSC-Derived Blood-Brain Barrier Chips Enable Disease Modeling and Personalized Medicine Applications.

Vatine GD, Barrile R, Workman MJ, Sances S, Barriga BK, Rahnama M, Barthakur S, Kasendra M, Lucchesi C, Kerns J, Wen N, Spivia WR, Chen Z, Van Eyk J, Svendsen CN.

Cell Stem Cell. 2019 Jun 6;24(6):995-1005.e6. doi: 10.1016/j.stem.2019.05.011.

PMID:
31173718
3.

Young bone marrow transplantation preserves learning and memory in old mice.

Das MM, Godoy M, Chen S, Moser VA, Avalos P, Roxas KM, Dang I, Yáñez A, Zhang W, Bresee C, Arditi M, Liu GY, Svendsen CN, Goodridge HS.

Commun Biol. 2019 Feb 20;2:73. doi: 10.1038/s42003-019-0298-5. eCollection 2019.

4.

In Vitro and In Vivo Proteomic Comparison of Human Neural Progenitor Cell-Induced Photoreceptor Survival.

Jones MK, Lu B, Chen DZ, Spivia WR, Mercado AT, Ljubimov AV, Svendsen CN, Van Eyk JE, Wang S.

Proteomics. 2019 Feb;19(3):e1800213. doi: 10.1002/pmic.201800213. Epub 2019 Jan 2.

PMID:
30515959
5.

Report of the international conference on manufacturing and testing of pluripotent stem cells.

Abbot S, Agbanyo F, Ahlfors JE, Baghbaderani BA, Bartido S, Bharti K, Burke C, Carlsson B, Cavagnaro J, Creasey A, DiGiusto D, Francissen K, Gaffney A, Goldring C, Gorba T, Griffiths E, Hanatani T, Hayakawa T, Heki T, Hoogendoorn K, Kawamata S, Kimura H, Kirkeby A, Knezevic I, Lebkowski J, Lin S, Lin-Gibson S, Lubiniecki A, O'Shea O, Pera M, Petricciani J, Pigeau G, Ratcliffe A, Sato Y, Schumann GG, Shingleton W, Stacey Chair G, Sullivan S, Svendsen CN, Trouvin JH, Vandeputte J, Yuan BZ, Zoon K.

Biologicals. 2018 Nov;56:67-83. doi: 10.1016/j.biologicals.2018.08.004. Epub 2018 Aug 24.

PMID:
30150108
6.

Stem cell transplantation for amyotrophic lateral sclerosis.

Baloh RH, Glass JD, Svendsen CN.

Curr Opin Neurol. 2018 Oct;31(5):655-661. doi: 10.1097/WCO.0000000000000598. Review.

PMID:
30080719
7.

Enhanced Utilization of Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids Using Microengineered Chips.

Workman MJ, Gleeson JP, Troisi EJ, Estrada HQ, Kerns SJ, Hinojosa CD, Hamilton GA, Targan SR, Svendsen CN, Barrett RJ.

Cell Mol Gastroenterol Hepatol. 2017 Dec 29;5(4):669-677.e2. doi: 10.1016/j.jcmgh.2017.12.008. eCollection 2018.

8.

Inducible Expression of GDNF in Transplanted iPSC-Derived Neural Progenitor Cells.

Akhtar AA, Gowing G, Kobritz N, Savinoff SE, Garcia L, Saxon D, Cho N, Kim G, Tom CM, Park H, Lawless G, Shelley BC, Mattis VB, Breunig JJ, Svendsen CN.

Stem Cell Reports. 2018 Jun 5;10(6):1696-1704. doi: 10.1016/j.stemcr.2018.03.024. Epub 2018 Apr 26.

9.

Transplantation of Neural Progenitor Cells Expressing Glial Cell Line-Derived Neurotrophic Factor into the Motor Cortex as a Strategy to Treat Amyotrophic Lateral Sclerosis.

Thomsen GM, Avalos P, Ma AA, Alkaslasi M, Cho N, Wyss L, Vit JP, Godoy M, Suezaki P, Shelest O, Bankiewicz KS, Svendsen CN.

Stem Cells. 2018 Jul;36(7):1122-1131. doi: 10.1002/stem.2825. Epub 2018 Apr 15.

10.

Human iPSC-Derived Endothelial Cells and Microengineered Organ-Chip Enhance Neuronal Development.

Sances S, Ho R, Vatine G, West D, Laperle A, Meyer A, Godoy M, Kay PS, Mandefro B, Hatata S, Hinojosa C, Wen N, Sareen D, Hamilton GA, Svendsen CN.

Stem Cell Reports. 2018 Apr 10;10(4):1222-1236. doi: 10.1016/j.stemcr.2018.02.012. Epub 2018 Mar 22.

11.

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

Nicolas A, Kenna KP, Renton AE, Ticozzi N, Faghri F, Chia R, Dominov JA, Kenna BJ, Nalls MA, Keagle P, Rivera AM, van Rheenen W, Murphy NA, van Vugt JJFA, Geiger JT, Van der Spek RA, Pliner HA, Shankaracharya, Smith BN, Marangi G, Topp SD, Abramzon Y, Gkazi AS, Eicher JD, Kenna A; ITALSGEN Consortium, Mora G, Calvo A, Mazzini L, Riva N, Mandrioli J, Caponnetto C, Battistini S, Volanti P, La Bella V, Conforti FL, Borghero G, Messina S, Simone IL, Trojsi F, Salvi F, Logullo FO, D'Alfonso S, Corrado L, Capasso M, Ferrucci L; Genomic Translation for ALS Care (GTAC) Consortium, Moreno CAM, Kamalakaran S, Goldstein DB; ALS Sequencing Consortium, Gitler AD, Harris T, Myers RM; NYGC ALS Consortium, Phatnani H, Musunuri RL, Evani US, Abhyankar A, Zody MC; Answer ALS Foundation, Kaye J, Finkbeiner S, Wyman SK, LeNail A, Lima L, Fraenkel E, Svendsen CN, Thompson LM, Van Eyk JE, Berry JD, Miller TM, Kolb SJ, Cudkowicz M, Baxi E; Clinical Research in ALS and Related Disorders for Therapeutic Development (CReATe) Consortium, Benatar M, Taylor JP, Rampersaud E, Wu G, Wuu J; SLAGEN Consortium, Lauria G, Verde F, Fogh I, Tiloca C, Comi GP, Sorarù G, Cereda C; French ALS Consortium, Corcia P, Laaksovirta H, Myllykangas L, Jansson L, Valori M, Ealing J, Hamdalla H, Rollinson S, Pickering-Brown S, Orrell RW, Sidle KC, Malaspina A, Hardy J, Singleton AB, Johnson JO, Arepalli S, Sapp PC, McKenna-Yasek D, Polak M, Asress S, Al-Sarraj S, King A, Troakes C, Vance C, de Belleroche J, Baas F, Ten Asbroek ALMA, Muñoz-Blanco JL, Hernandez DG, Ding J, Gibbs JR, Scholz SW, Floeter MK, Campbell RH, Landi F, Bowser R, Pulst SM, Ravits JM, MacGowan DJL, Kirby J, Pioro EP, Pamphlett R, Broach J, Gerhard G, Dunckley TL, Brady CB, Kowall NW, Troncoso JC, Le Ber I, Mouzat K, Lumbroso S, Heiman-Patterson TD, Kamel F, Van Den Bosch L, Baloh RH, Strom TM, Meitinger T, Shatunov A, Van Eijk KR, de Carvalho M, Kooyman M, Middelkoop B, Moisse M, McLaughlin RL, Van Es MA, Weber M, Boylan KB, Van Blitterswijk M, Rademakers R, Morrison KE, Basak AN, Mora JS, Drory VE, Shaw PJ, Turner MR, Talbot K, Hardiman O, Williams KL, Fifita JA, Nicholson GA, Blair IP, Rouleau GA, Esteban-Pérez J, García-Redondo A, Al-Chalabi A; Project MinE ALS Sequencing Consortium, Rogaeva E, Zinman L, Ostrow LW, Maragakis NJ, Rothstein JD, Simmons Z, Cooper-Knock J, Brice A, Goutman SA, Feldman EL, Gibson SB, Taroni F, Ratti A, Gellera C, Van Damme P, Robberecht W, Fratta P, Sabatelli M, Lunetta C, Ludolph AC, Andersen PM, Weishaupt JH, Camu W, Trojanowski JQ, Van Deerlin VM, Brown RH Jr, van den Berg LH, Veldink JH, Harms MB, Glass JD, Stone DJ, Tienari P, Silani V, Chiò A, Shaw CE, Traynor BJ, Landers JE.

Neuron. 2018 Mar 21;97(6):1268-1283.e6. doi: 10.1016/j.neuron.2018.02.027.

12.

Huntington modeling improves with age.

Mattis VB, Svendsen CN.

Nat Neurosci. 2018 Mar;21(3):301-303. doi: 10.1038/s41593-018-0086-4. No abstract available.

PMID:
29476127
13.

Faulty neuronal determination and cell polarization are reverted by modulating HD early phenotypes.

Conforti P, Besusso D, Bocchi VD, Faedo A, Cesana E, Rossetti G, Ranzani V, Svendsen CN, Thompson LM, Toselli M, Biella G, Pagani M, Cattaneo E.

Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):E762-E771. doi: 10.1073/pnas.1715865115. Epub 2018 Jan 8. Erratum in: Proc Natl Acad Sci U S A. 2018 Feb 20;:.

14.

The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations.

Keenan AB, Jenkins SL, Jagodnik KM, Koplev S, He E, Torre D, Wang Z, Dohlman AB, Silverstein MC, Lachmann A, Kuleshov MV, Ma'ayan A, Stathias V, Terryn R, Cooper D, Forlin M, Koleti A, Vidovic D, Chung C, Schürer SC, Vasiliauskas J, Pilarczyk M, Shamsaei B, Fazel M, Ren Y, Niu W, Clark NA, White S, Mahi N, Zhang L, Kouril M, Reichard JF, Sivaganesan S, Medvedovic M, Meller J, Koch RJ, Birtwistle MR, Iyengar R, Sobie EA, Azeloglu EU, Kaye J, Osterloh J, Haston K, Kalra J, Finkbiener S, Li J, Milani P, Adam M, Escalante-Chong R, Sachs K, Lenail A, Ramamoorthy D, Fraenkel E, Daigle G, Hussain U, Coye A, Rothstein J, Sareen D, Ornelas L, Banuelos M, Mandefro B, Ho R, Svendsen CN, Lim RG, Stocksdale J, Casale MS, Thompson TG, Wu J, Thompson LM, Dardov V, Venkatraman V, Matlock A, Van Eyk JE, Jaffe JD, Papanastasiou M, Subramanian A, Golub TR, Erickson SD, Fallahi-Sichani M, Hafner M, Gray NS, Lin JR, Mills CE, Muhlich JL, Niepel M, Shamu CE, Williams EH, Wrobel D, Sorger PK, Heiser LM, Gray JW, Korkola JE, Mills GB, LaBarge M, Feiler HS, Dane MA, Bucher E, Nederlof M, Sudar D, Gross S, Kilburn DF, Smith R, Devlin K, Margolis R, Derr L, Lee A, Pillai A.

Cell Syst. 2018 Jan 24;6(1):13-24. doi: 10.1016/j.cels.2017.11.001. Epub 2017 Nov 29. Review.

15.

Directed Differentiation of Human Induced Pluripotent Stem Cells into Fallopian Tube Epithelium.

Yucer N, Holzapfel M, Jenkins Vogel T, Lenaeus L, Ornelas L, Laury A, Sareen D, Barrett R, Karlan BY, Svendsen CN.

Sci Rep. 2017 Sep 6;7(1):10741. doi: 10.1038/s41598-017-05519-2.

16.

Concise Review: Stem Cells for Corneal Wound Healing.

Saghizadeh M, Kramerov AA, Svendsen CN, Ljubimov AV.

Stem Cells. 2017 Oct;35(10):2105-2114. doi: 10.1002/stem.2667. Epub 2017 Jul 26. Review.

17.

Patients with ALS show highly correlated progression rates in left and right limb muscles.

Rushton DJ, Andres PL, Allred P, Baloh RH, Svendsen CN.

Neurology. 2017 Jul 11;89(2):196-206. doi: 10.1212/WNL.0000000000004105. Epub 2017 Jun 9.

18.

Ex vivo gene therapy for the treatment of neurological disorders.

Gowing G, Svendsen S, Svendsen CN.

Prog Brain Res. 2017;230:99-132. doi: 10.1016/bs.pbr.2016.11.003. Epub 2017 Jan 17. Review.

PMID:
28552237
19.

Modeling Psychomotor Retardation using iPSCs from MCT8-Deficient Patients Indicates a Prominent Role for the Blood-Brain Barrier.

Vatine GD, Al-Ahmad A, Barriga BK, Svendsen S, Salim A, Garcia L, Garcia VJ, Ho R, Yucer N, Qian T, Lim RG, Wu J, Thompson LM, Spivia WR, Chen Z, Van Eyk J, Palecek SP, Refetoff S, Shusta EV, Svendsen CN.

Cell Stem Cell. 2017 Jun 1;20(6):831-843.e5. doi: 10.1016/j.stem.2017.04.002. Epub 2017 May 16.

20.

Huntington's Disease iPSC-Derived Brain Microvascular Endothelial Cells Reveal WNT-Mediated Angiogenic and Blood-Brain Barrier Deficits.

Lim RG, Quan C, Reyes-Ortiz AM, Lutz SE, Kedaigle AJ, Gipson TA, Wu J, Vatine GD, Stocksdale J, Casale MS, Svendsen CN, Fraenkel E, Housman DE, Agalliu D, Thompson LM.

Cell Rep. 2017 May 16;19(7):1365-1377. doi: 10.1016/j.celrep.2017.04.021.

21.

Systemic injection of AAV9-GDNF provides modest functional improvements in the SOD1G93A ALS rat but has adverse side effects.

Thomsen GM, Alkaslasi M, Vit JP, Lawless G, Godoy M, Gowing G, Shelest O, Svendsen CN.

Gene Ther. 2017 Apr;24(4):245-252. doi: 10.1038/gt.2017.9. Epub 2017 Mar 9.

22.

Human Neural Progenitor Transplantation Rescues Behavior and Reduces α-Synuclein in a Transgenic Model of Dementia with Lewy Bodies.

Goldberg NRS, Marsh SE, Ochaba J, Shelley BC, Davtyan H, Thompson LM, Steffan JS, Svendsen CN, Blurton-Jones M.

Stem Cells Transl Med. 2017 Jun;6(6):1477-1490. doi: 10.1002/sctm.16-0362. Epub 2017 Feb 22.

23.

Ferumoxytol Labeling of Human Neural Progenitor Cells for Diagnostic Cellular Tracking in the Porcine Spinal Cord with Magnetic Resonance Imaging.

Lamanna JJ, Gutierrez J, Urquia LN, Hurtig CV, Amador E, Grin N, Svendsen CN, Federici T, Oshinski JN, Boulis NM.

Stem Cells Transl Med. 2017 Jan;6(1):139-150. doi: 10.5966/sctm.2015-0422. Epub 2016 Aug 29.

24.

An isogenic blood-brain barrier model comprising brain endothelial cells, astrocytes, and neurons derived from human induced pluripotent stem cells.

Canfield SG, Stebbins MJ, Morales BS, Asai SW, Vatine GD, Svendsen CN, Palecek SP, Shusta EV.

J Neurochem. 2017 Mar;140(6):874-888. doi: 10.1111/jnc.13923. Epub 2017 Feb 14.

25.

A model of recurrent concussion that leads to long-term motor deficits, CTE-like tauopathy and exacerbation of an ALS phenotype.

Thomsen GM, Ma AM, Ko A, Harada MY, Wyss L, Haro PS, Vit JP, Shelest O, Rhee P, Svendsen CN, Ley EJ.

J Trauma Acute Care Surg. 2016 Dec;81(6):1070-1079.

PMID:
27602892
26.

Transcriptome and proteome characterization of surface ectoderm cells differentiated from human iPSCs.

Qu Y, Zhou B, Yang W, Han B, Yu-Rice Y, Gao B, Johnson J, Svendsen CN, Freeman MR, Giuliano AE, Sareen D, Cui X.

Sci Rep. 2016 Aug 23;6:32007. doi: 10.1038/srep32007.

27.

ALS disrupts spinal motor neuron maturation and aging pathways within gene co-expression networks.

Ho R, Sances S, Gowing G, Amoroso MW, O'Rourke JG, Sahabian A, Wichterle H, Baloh RH, Sareen D, Svendsen CN.

Nat Neurosci. 2016 Sep;19(9):1256-67. doi: 10.1038/nn.4345. Epub 2016 Jul 18.

28.

Cell freezing protocol suitable for ATAC-Seq on motor neurons derived from human induced pluripotent stem cells.

Milani P, Escalante-Chong R, Shelley BC, Patel-Murray NL, Xin X, Adam M, Mandefro B, Sareen D, Svendsen CN, Fraenkel E.

Sci Rep. 2016 May 5;6:25474. doi: 10.1038/srep25474.

29.

Human neural progenitors differentiate into astrocytes and protect motor neurons in aging rats.

Das MM, Avalos P, Suezaki P, Godoy M, Garcia L, Chang CD, Vit JP, Shelley B, Gowing G, Svendsen CN.

Exp Neurol. 2016 Jun;280:41-9. doi: 10.1016/j.expneurol.2016.03.023. Epub 2016 Mar 29.

PMID:
27032721
30.

Modeling ALS with motor neurons derived from human induced pluripotent stem cells.

Sances S, Bruijn LI, Chandran S, Eggan K, Ho R, Klim JR, Livesey MR, Lowry E, Macklis JD, Rushton D, Sadegh C, Sareen D, Wichterle H, Zhang SC, Svendsen CN.

Nat Neurosci. 2016 Apr;19(4):542-53. doi: 10.1038/nn.4273. Review.

31.

Mifepristone-inducible transgene expression in neural progenitor cells in vitro and in vivo.

Hjelm BE, Grunseich C, Gowing G, Avalos P, Tian J, Shelley BC, Mooney M, Narwani K, Shi Y, Svendsen CN, Wolfe JH, Fischbeck KH, Pierson TM.

Gene Ther. 2016 May;23(5):424-37. doi: 10.1038/gt.2016.13. Epub 2016 Feb 10.

32.

In Vivo CRISPR/Cas9 Gene Editing Corrects Retinal Dystrophy in the S334ter-3 Rat Model of Autosomal Dominant Retinitis Pigmentosa.

Bakondi B, Lv W, Lu B, Jones MK, Tsai Y, Kim KJ, Levy R, Akhtar AA, Breunig JJ, Svendsen CN, Wang S.

Mol Ther. 2016 Mar;24(3):556-63. doi: 10.1038/mt.2015.220. Epub 2015 Dec 15.

33.

Ex Vivo Gene Therapy Using Human Mesenchymal Stem Cells to Deliver Growth Factors in the Skeletal Muscle of a Familial ALS Rat Model.

Suzuki M, Svendsen CN.

Methods Mol Biol. 2016;1382:325-36. doi: 10.1007/978-1-4939-3271-9_24.

PMID:
26611598
34.

Acute Traumatic Brain Injury Does Not Exacerbate Amyotrophic Lateral Sclerosis in the SOD1 (G93A) Rat Model

Thomsen GM, Vit JP, Lamb A, Gowing G, Shelest O, Alkaslasi M, Ley EJ, Svendsen CN.

eNeuro. 2015 Jul 3;2(3). pii: ENEURO.0059-14.2015. doi: 10.1523/ENEURO.0059-14.2015. eCollection 2015 May-Jun.

35.

Modeling Huntington׳s disease with patient-derived neurons.

Mattis VB, Svendsen CN.

Brain Res. 2017 Feb 1;1656:76-87. doi: 10.1016/j.brainres.2015.10.001. Epub 2015 Oct 13. Review.

PMID:
26459990
36.

Quantitative high-throughput gene expression profiling of human striatal development to screen stem cell-derived medium spiny neurons.

Straccia M, Garcia-Diaz Barriga G, Sanders P, Bombau G, Carrere J, Mairal PB, Vinh NN, Yung S, Kelly CM, Svendsen CN, Kemp PJ, Arjomand J, Schoenfeld RC, Alberch J, Allen ND, Rosser AE, Canals JM.

Mol Ther Methods Clin Dev. 2015 Sep 16;2:15030. doi: 10.1038/mtm.2015.30. eCollection 2015.

37.

Regenerative cellular therapies for neurologic diseases.

Levy M, Boulis N, Rao M, Svendsen CN.

Brain Res. 2016 May 1;1638(Pt A):88-96. doi: 10.1016/j.brainres.2015.06.053. Epub 2015 Jul 31. Review.

38.

Low-Dose Irradiation Enhances Gene Targeting in Human Pluripotent Stem Cells.

Hatada S, Subramanian A, Mandefro B, Ren S, Kim HW, Tang J, Funari V, Baloh RH, Sareen D, Arumugaswami V, Svendsen CN.

Stem Cells Transl Med. 2015 Sep;4(9):998-1010. doi: 10.5966/sctm.2015-0050. Epub 2015 Jul 16.

39.

In Vivo Tracking of Human Neural Progenitor Cells in the Rat Brain Using Magnetic Resonance Imaging Is Not Enhanced by Ferritin Expression.

Bernau K, Lewis CM, Petelinsek AM, Reagan MS, Niles DJ, Mattis VB, Meyerand ME, Suzuki M, Svendsen CN.

Cell Transplant. 2016;25(3):575-92. doi: 10.3727/096368915X688614. Epub 2015 Jul 8.

40.

Preclinical Validation of Multilevel Intraparenchymal Stem Cell Therapy in the Porcine Spinal Cord.

Gutierrez J, Lamanna JJ, Grin N, Hurtig CV, Miller JH, Riley J, Urquia L, Avalos P, Svendsen CN, Federici T, Boulis NM.

Neurosurgery. 2015 Oct;77(4):604-12; discussion 612. doi: 10.1227/NEU.0000000000000882.

PMID:
26134596
41.

Human iPSC-Derived Neural Progenitors Preserve Vision in an AMD-Like Model.

Tsai Y, Lu B, Bakondi B, Girman S, Sahabian A, Sareen D, Svendsen CN, Wang S.

Stem Cells. 2015 Aug;33(8):2537-49. doi: 10.1002/stem.2032. Epub 2015 Jun 2.

42.

HD iPSC-derived neural progenitors accumulate in culture and are susceptible to BDNF withdrawal due to glutamate toxicity.

Mattis VB, Tom C, Akimov S, Saeedian J, Østergaard ME, Southwell AL, Doty CN, Ornelas L, Sahabian A, Lenaeus L, Mandefro B, Sareen D, Arjomand J, Hayden MR, Ross CA, Svendsen CN.

Hum Mol Genet. 2015 Jun 1;24(11):3257-71. doi: 10.1093/hmg/ddv080. Epub 2015 Mar 3.

43.

Kuwanon V inhibits proliferation, promotes cell survival and increases neurogenesis of neural stem cells.

Kong SY, Park MH, Lee M, Kim JO, Lee HR, Han BW, Svendsen CN, Sung SH, Kim HJ.

PLoS One. 2015 Feb 23;10(2):e0118188. doi: 10.1371/journal.pone.0118188. eCollection 2015.

44.

A Subsequent Human Neural Progenitor Transplant into the Degenerate Retina Does Not Compromise Initial Graft Survival or Therapeutic Efficacy.

Lu B, Lin Y, Tsai Y, Girman S, Adamus G, Jones MK, Shelley B, Svendsen CN, Wang S.

Transl Vis Sci Technol. 2015 Feb 10;4(1):7. eCollection 2015 Feb.

45.

Targeting ATM ameliorates mutant Huntingtin toxicity in cell and animal models of Huntington's disease.

Lu XH, Mattis VB, Wang N, Al-Ramahi I, van den Berg N, Fratantoni SA, Waldvogel H, Greiner E, Osmand A, Elzein K, Xiao J, Dijkstra S, de Pril R, Vinters HV, Faull R, Signer E, Kwak S, Marugan JJ, Botas J, Fischer DF, Svendsen CN, Munoz-Sanjuan I, Yang XW.

Sci Transl Med. 2014 Dec 24;6(268):268ra178. doi: 10.1126/scitranslmed.3010523.

PMID:
25540325
46.

Astrocytes show reduced support of motor neurons with aging that is accelerated in a rodent model of ALS.

Das MM, Svendsen CN.

Neurobiol Aging. 2015 Feb;36(2):1130-9. doi: 10.1016/j.neurobiolaging.2014.09.020. Epub 2014 Sep 28.

PMID:
25443290
47.

Delayed disease onset and extended survival in the SOD1G93A rat model of amyotrophic lateral sclerosis after suppression of mutant SOD1 in the motor cortex.

Thomsen GM, Gowing G, Latter J, Chen M, Vit JP, Staggenborg K, Avalos P, Alkaslasi M, Ferraiuolo L, Likhite S, Kaspar BK, Svendsen CN.

J Neurosci. 2014 Nov 19;34(47):15587-600. doi: 10.1523/JNEUROSCI.2037-14.2014.

48.

Reliable generation of induced pluripotent stem cells from human lymphoblastoid cell lines.

Barrett R, Ornelas L, Yeager N, Mandefro B, Sahabian A, Lenaeus L, Targan SR, Svendsen CN, Sareen D.

Stem Cells Transl Med. 2014 Dec;3(12):1429-34. doi: 10.5966/sctm.2014-0121. Epub 2014 Oct 8.

49.

Stem cells for cell replacement therapy: a therapeutic strategy for HD?

Rosser A, Svendsen CN.

Mov Disord. 2014 Sep 15;29(11):1446-54. doi: 10.1002/mds.26026. Review.

PMID:
25216372
50.

Differentiation of human limbal-derived induced pluripotent stem cells into limbal-like epithelium.

Sareen D, Saghizadeh M, Ornelas L, Winkler MA, Narwani K, Sahabian A, Funari VA, Tang J, Spurka L, Punj V, Maguen E, Rabinowitz YS, Svendsen CN, Ljubimov AV.

Stem Cells Transl Med. 2014 Sep;3(9):1002-12. doi: 10.5966/sctm.2014-0076. Epub 2014 Jul 28.

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