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Items: 19


Defective exocytosis and processing of insulin in a cystic fibrosis mouse model.

Edlund A, Barghouth M, Huhn M, Abels M, Esguerra J, Mollet I, Svedin E, Wendt A, Renstrom E, Zhang E, Wierup N, Scholte BJ, Flodström-Tullberg M, Eliasson L.

J Endocrinol. 2019 Feb 1. pii: JOE-18-0570.R1. doi: 10.1530/JOE-18-0570. [Epub ahead of print]


New Coxsackievirus 2Apro and 3Cpro protease antibodies for virus detection and discovery of pathogenic mechanisms.

Laitinen OH, Svedin E, Kapell S, Hankaniemi MM, Larsson PG, Domsgen E, Stone VM, Määttä JAE, Hyöty H, Hytönen VP, Flodström-Tullberg M.

J Virol Methods. 2018 May;255:29-37. doi: 10.1016/j.jviromet.2018.02.001. Epub 2018 Feb 6.


A Coxsackievirus B vaccine protects against virus-induced diabetes in an experimental mouse model of type 1 diabetes.

Stone VM, Hankaniemi MM, Svedin E, Sioofy-Khojine A, Oikarinen S, Hyöty H, Laitinen OH, Hytönen VP, Flodström-Tullberg M.

Diabetologia. 2018 Feb;61(2):476-481. doi: 10.1007/s00125-017-4492-z. Epub 2017 Nov 18.


A Link Between a Common Mutation in CFTR and Impaired Innate and Adaptive Viral Defense.

Svedin E, Utorova R, Hühn MH, Larsson PG, Stone VM, Garimella M, Lind K, Hägglöf T, Pincikova T, Laitinen OH, McInerney GM, Scholte B, Hjelte L, Karlsson MCI, Flodström-Tullberg M.

J Infect Dis. 2017 Dec 5;216(10):1308-1317. doi: 10.1093/infdis/jix474.


Composition and functionality of the intrahepatic innate lymphoid cell-compartment in human nonfibrotic and fibrotic livers.

Forkel M, Berglin L, Kekäläinen E, Carlsson A, Svedin E, Michaëlsson J, Nagasawa M, Erjefält JS, Mori M, Flodström-Tullberg M, Bergquist A, Ljunggren HG, Westgren M, Lindforss U, Friberg D, Jorns C, Ellis E, Björkström NK, Mjösberg J.

Eur J Immunol. 2017 Aug;47(8):1280-1294. doi: 10.1002/eji.201646890. Epub 2017 Jul 11.


Enteroviral proteases: structure, host interactions and pathogenicity.

Laitinen OH, Svedin E, Kapell S, Nurminen A, Hytönen VP, Flodström-Tullberg M.

Rev Med Virol. 2016 Jul;26(4):251-67. doi: 10.1002/rmv.1883. Epub 2016 May 4. Review.


Cross-Talk Between Sporophyte and Gametophyte Generations Is Promoted by CHD3 Chromatin Remodelers in Arabidopsis thaliana.

Carter B, Henderson JT, Svedin E, Fiers M, McCarthy K, Smith A, Guo C, Bishop B, Zhang H, Riksen T, Shockley A, Dilkes BP, Boutilier K, Ogas J.

Genetics. 2016 Jun;203(2):817-29. doi: 10.1534/genetics.115.180141. Epub 2016 Apr 13.


Coxsackievirus counters the host innate immune response by blocking type III interferon expression.

Lind K, Svedin E, Domsgen E, Kapell S, Laitinen OH, Moll M, Flodström-Tullberg M.

J Gen Virol. 2016 Jun;97(6):1368-1380. doi: 10.1099/jgv.0.000443. Epub 2016 Mar 2.


Cystic fibrosis bronchial epithelial cells have impaired ability to activate vitamin D.

Pincikova T, Svedin E, Domsgen E, Flodström-Tullberg M, Hjelte L.

Acta Paediatr. 2016 Jul;105(7):851-3. doi: 10.1111/apa.13361. Epub 2016 Mar 28. No abstract available.


Discovery of a novel amino acid racemase through exploration of natural variation in Arabidopsis thaliana.

Strauch RC, Svedin E, Dilkes B, Chapple C, Li X.

Proc Natl Acad Sci U S A. 2015 Sep 15;112(37):11726-31. doi: 10.1073/pnas.1503272112. Epub 2015 Aug 31.


Exploiting natural variation of secondary metabolism identifies a gene controlling the glycosylation diversity of dihydroxybenzoic acids in Arabidopsis thaliana.

Li X, Svedin E, Mo H, Atwell S, Dilkes BP, Chapple C.

Genetics. 2014 Nov;198(3):1267-76. doi: 10.1534/genetics.114.168690. Epub 2014 Aug 29.


Calcium current inactivation rather than pool depletion explains reduced exocytotic rate with prolonged stimulation in insulin-secreting INS-1 832/13 cells.

Pedersen MG, Salunkhe VA, Svedin E, Edlund A, Eliasson L.

PLoS One. 2014 Aug 8;9(8):e103874. doi: 10.1371/journal.pone.0103874. eCollection 2014.


Type III interferons are expressed by Coxsackievirus-infected human primary hepatocytes and regulate hepatocyte permissiveness to infection.

Lind K, Svedin E, Utorova R, Stone VM, Flodström-Tullberg M.

Clin Exp Immunol. 2014 Sep;177(3):687-95. doi: 10.1111/cei.12368.


Detection of enterovirus in the islet cells of patients with type 1 diabetes: what do we learn from immunohistochemistry? Reply to Hansson SF, Korsgren S, Pontén F et al [letter].

Richardson SJ, Leete P, Dhayal S, Russell MA, Oikarinen M, Laiho JE, Svedin E, Lind K, Rosenling T, Chapman N, Bone AJ, Foulis AK, Frisk G, Flodström-Tullberg M, Hober D, Hyoty H, Pugliese A, Morgan NG.

Diabetologia. 2014 Mar;57(3):647-9. doi: 10.1007/s00125-014-3167-2. Epub 2014 Jan 16. No abstract available.


Evaluation of the fidelity of immunolabelling obtained with clone 5D8/1, a monoclonal antibody directed against the enteroviral capsid protein, VP1, in human pancreas.

Richardson SJ, Leete P, Dhayal S, Russell MA, Oikarinen M, Laiho JE, Svedin E, Lind K, Rosenling T, Chapman N, Bone AJ; nPOD-V Consortium, Foulis AK, Frisk G, Flodstrom-Tullberg M, Hober D, Hyoty H, Morgan NG.

Diabetologia. 2014 Feb;57(2):392-401. doi: 10.1007/s00125-013-3094-7. Epub 2013 Nov 5.


Previous maternal infection protects offspring from enterovirus infection and prevents experimental diabetes development in mice.

Larsson PG, Lakshmikanth T, Svedin E, King C, Flodström-Tullberg M.

Diabetologia. 2013 Apr;56(4):867-74. doi: 10.1007/s00125-013-2834-z. Epub 2013 Jan 24.


Genetic adaptation associated with genome-doubling in autotetraploid Arabidopsis arenosa.

Hollister JD, Arnold BJ, Svedin E, Xue KS, Dilkes BP, Bomblies K.

PLoS Genet. 2012;8(12):e1003093. doi: 10.1371/journal.pgen.1003093. Epub 2012 Dec 20.


New Diversity Arrays Technology (DArT) markers for tetraploid oat (Avena magna Murphy et Terrell) provide the first complete oat linkage map and markers linked to domestication genes from hexaploid A. sativa L.

Oliver RE, Jellen EN, Ladizinsky G, Korol AB, Kilian A, Beard JL, Dumlupinar Z, Wisniewski-Morehead NH, Svedin E, Coon M, Redman RR, Maughan PJ, Obert DE, Jackson EW.

Theor Appl Genet. 2011 Nov;123(7):1159-71. doi: 10.1007/s00122-011-1656-y. Epub 2011 Jul 31.


Melanoma differentiation-associated protein-5 (MDA-5) limits early viral replication but is not essential for the induction of type 1 interferons after Coxsackievirus infection.

Hühn MH, McCartney SA, Lind K, Svedin E, Colonna M, Flodström-Tullberg M.

Virology. 2010 May 25;401(1):42-8. doi: 10.1016/j.virol.2010.02.010. Epub 2010 Mar 5.

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