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Items: 9

1.

Discovery of a Novel Oral Glucocorticoid Receptor Modulator (AZD9567) with Improved Side Effect Profile.

Ripa L, Edman K, Dearman M, Edenro G, Hendrickx R, Ullah V, Chang HF, Lepistö M, Chapman D, Geschwindner S, Wissler L, Svanberg P, Lawitz K, Malmberg J, Nikitidis A, Olsson RI, Bird J, Llinas A, Hegelund-Myrbäck T, Berger M, Thorne P, Harrison R, Köhler C, Drmota T.

J Med Chem. 2018 Mar 8;61(5):1785-1799. doi: 10.1021/acs.jmedchem.7b01690. Epub 2018 Feb 16.

PMID:
29424542
2.

An S-warfarin and AZD1981 interaction: in vitro and clinical pilot data suggest the N-deacetylated amino acid metabolite as the primary perpetrator.

Grime K, Pehrson R, Nordell P, Gillen M, Kühn W, Mant T, Brännström M, Svanberg P, Jones B, Brealey C.

Br J Clin Pharmacol. 2017 Feb;83(2):381-392. doi: 10.1111/bcp.13102. Epub 2016 Oct 13.

3.

Determination of Human Hepatocyte Intrinsic Clearance for Slowly Metabolized Compounds: Comparison of a Primary Hepatocyte/Stromal Cell Co-culture with Plated Primary Hepatocytes and HepaRG.

Bonn B, Svanberg P, Janefeldt A, Hultman Ia, Grime K.

Drug Metab Dispos. 2016 Apr;44(4):527-33. doi: 10.1124/dmd.115.067769. Epub 2016 Feb 5.

4.

Development of a Novel Lung Slice Methodology for Profiling of Inhaled Compounds.

Bäckström E, Lundqvist A, Boger E, Svanberg P, Ewing P, Hammarlund-Udenaes M, Fridén M.

J Pharm Sci. 2016 Feb;105(2):838-845. doi: 10.1002/jps.24575. Epub 2016 Jan 11.

PMID:
26178700
5.

Predicting metabolic clearance for drugs that are actively transported into hepatocytes: incubational binding as a consequence of in vitro hepatocyte concentration is a key factor.

Nordell P, Svanberg P, Bird J, Grime K.

Drug Metab Dispos. 2013 Apr;41(4):836-43. doi: 10.1124/dmd.112.050377. Epub 2013 Jan 30.

6.

Optimized experimental design for the estimation of enzyme kinetic parameters: an experimental evaluation.

Sjögren E, Svanberg P, Kanebratt KP.

Drug Metab Dispos. 2012 Dec;40(12):2273-9. doi: 10.1124/dmd.112.047373. Epub 2012 Aug 31.

7.

Promoting a secure attachment: A primary prevention practice model.

Svanberg PO, Mennet L, Spieker S.

Clin Child Psychol Psychiatry. 2010 Jul;15(3):363-78. doi: 10.1177/1359104510367584.

PMID:
20603424
8.

Estimation of trends in urban traffic NOx emissions by an empirical model

Persson K, Omstedt G, Lenner M, Sjodin A, Svanberg PA.

Sci Total Environ. 1999 Sep 1;235(1-3):367-9.

PMID:
10535131
9.

Verification of expected trends in urban traffic NOx emissions from long-term measurements of ambient NO2 concentrations in urban air.

Sjödin A, Sjöberg K, Svanberg PA, Backström H.

Sci Total Environ. 1996 Oct 28;189-190:213-20.

PMID:
8865678

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