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Items: 1 to 50 of 244

1.

Pathogenic Epigenetic Consequences of Genetic Alterations in IDH-Wild-Type Diffuse Astrocytic Gliomas.

Ohka F, Shinjo K, Deguchi S, Matsui Y, Okuno Y, Katsushima K, Suzuki M, Kato A, Ogiso N, Yamamichi A, Aoki K, Suzuki H, Sato S, Arul Rayan N, Prabhakar S, Göke J, Shimamura T, Maruyama R, Takahashi S, Suzumura A, Kimura H, Wakabayashi T, Zong H, Natsume A, Kondo Y.

Cancer Res. 2019 Oct 1;79(19):4814-4827. doi: 10.1158/0008-5472.CAN-19-1272. Epub 2019 Aug 20.

PMID:
31431463
2.

In Vitro Epiretinal Membrane Model and Antibody Permeability: Relationship With Anti-VEGF Resistance in Diabetic Macular Edema.

Namba R, Kaneko H, Suzumura A, Shimizu H, Kataoka K, Takayama K, Yamada K, Funahashi Y, Ito S, Nonobe N, Terasaki H.

Invest Ophthalmol Vis Sci. 2019 Jul 1;60(8):2942-2949. doi: 10.1167/iovs.19-26788.

PMID:
31284311
3.

Development of a High-Throughput Screening Method for Oxide-Ion Conductors and Its Application to Bismuth-Based Oxide Library Thin Films.

Matsubara M, Suzumura A, Tajima S, Asahi R.

ACS Comb Sci. 2019 May 13;21(5):400-407. doi: 10.1021/acscombsci.8b00193. Epub 2019 Mar 18.

PMID:
30844232
4.

Biological Characteristics of Subsilicone Oil Fluid and Differences With Other Ocular Humors.

Shimizu H, Kaneko H, Suzumura A, Takayama K, Namba R, Funahashi Y, Kataoka K, Iwase T, Hwang SJ, Ito S, Yamada K, Ueno S, Ito Y, Terasaki H.

Transl Vis Sci Technol. 2019 Feb 28;8(1):28. doi: 10.1167/tvst.8.1.28. eCollection 2019 Jan.

5.

Silicone oil-associated retinal light exposure under a surgical microscope.

Yamada K, Kaneko H, Tsunekawa T, Shimizu H, Suzumura A, Namba R, Takeuchi J, Kataoka K, Takayama K, Inoue M, Ito Y, Terasaki H.

Acta Ophthalmol. 2019 Aug;97(5):e742-e746. doi: 10.1111/aos.14038. Epub 2019 Jan 30.

PMID:
30698352
6.

Novel Classification of Early-stage Systemic Hypertensive Changes in Human Retina Based on OCTA Measurement of Choriocapillaris.

Takayama K, Kaneko H, Ito Y, Kataoka K, Iwase T, Yasuma T, Matsuura T, Tsunekawa T, Shimizu H, Suzumura A, Ra E, Akahori T, Terasaki H.

Sci Rep. 2018 Oct 11;8(1):15163. doi: 10.1038/s41598-018-33580-y.

7.

Cathepsin C modulates myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis.

Durose WW, Shimizu T, Li J, Abe M, Sakimura K, Chetsawang B, Tanaka KF, Suzumura A, Tohyama K, Ikenaka K.

J Neurochem. 2019 Feb;148(3):413-425. doi: 10.1111/jnc.14581. Epub 2018 Dec 3.

PMID:
30152001
8.

Maternal separation as a risk factor for aggravation of neuropathic pain in later life in mice.

Mizoguchi H, Fukumoto K, Sakamoto G, Jin S, Toyama A, Wang T, Suzumura A, Sato J.

Behav Brain Res. 2019 Feb 1;359:942-949. doi: 10.1016/j.bbr.2018.06.015. Epub 2018 Jun 20.

PMID:
29935275
9.

Administration of molecular hydrogen during pregnancy improves behavioral abnormalities of offspring in a maternal immune activation model.

Imai K, Kotani T, Tsuda H, Nakano T, Ushida T, Iwase A, Nagai T, Toyokuni S, Suzumura A, Kikkawa F.

Sci Rep. 2018 Jun 15;8(1):9221. doi: 10.1038/s41598-018-27626-4.

10.

Treatment for paraneoplastic neuromyelitis optica spectrum disorder (NMOsd): Probable effects of tocilizumab for both cancer and NMOsd.

Tanaka M, Yanagida H, Suzumura A.

Mult Scler Relat Disord. 2018 Feb;20:82-83. doi: 10.1016/j.msard.2017.12.002. Epub 2017 Dec 20. No abstract available.

PMID:
29353735
11.

OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY OF THE FOVEAL AVASCULAR ZONE IN CHILDREN WITH A HISTORY OF TREATMENT-REQUIRING RETINOPATHY OF PREMATURITY.

Nonobe N, Kaneko H, Ito Y, Takayama K, Kataoka K, Tsunekawa T, Matsuura T, Suzumura A, Shimizu H, Terasaki H.

Retina. 2019 Jan;39(1):111-117. doi: 10.1097/IAE.0000000000001937.

PMID:
29190231
12.

[The Role of Microglia in Neuroinflammation].

Suzumura A.

Brain Nerve. 2017 Sep;69(9):975-984. doi: 10.11477/mf.1416200857. Japanese.

PMID:
28900060
13.

Cytokine profiling in the sub-silicone oil fluid after vitrectomy surgeries for refractory retinal diseases.

Kaneko H, Takayama K, Asami T, Ito Y, Tsunekawa T, Iwase T, Funahashi Y, Ueno S, Nonobe N, Yasuda S, Suzumura A, Shimizu H, Kimoto R, Hwang SJ, Terasaki H.

Sci Rep. 2017 May 25;7(1):2640. doi: 10.1038/s41598-017-03124-x.

14.

Correlation between miR-148 Expression in Vitreous and Severity of Rhegmatogenous Retinal Detachment.

Tsunekawa T, Kaneko H, Takayama K, Hwang SJ, Oishi A, Nagasaka Y, Ye F, Iwase T, Nonobe N, Ueno S, Ito Y, Yasuda S, Matsuura T, Shimizu H, Suzumura A, Kataoka K, Terasaki H.

Biomed Res Int. 2017;2017:3427319. doi: 10.1155/2017/3427319. Epub 2017 Feb 5.

15.

Better Visual Outcome by Intraocular Lens Ejection in Geriatric Patients with Ruptured Ocular Injuries.

Kaneko H, Asami T, Sugita T, Tsunekawa T, Matsuura T, Takayama K, Yamamoto K, Kachi S, Ito Y, Ueno S, Nonobe N, Kataoka K, Suzumura A, Iwase T, Terasaki H.

PLoS One. 2017 Jan 20;12(1):e0170094. doi: 10.1371/journal.pone.0170094. eCollection 2017.

16.

Th1 cells downregulate connexin 43 gap junctions in astrocytes via microglial activation.

Watanabe M, Masaki K, Yamasaki R, Kawanokuchi J, Takeuchi H, Matsushita T, Suzumura A, Kira JI.

Sci Rep. 2016 Dec 8;6:38387. doi: 10.1038/srep38387.

17.

Fractalkine attenuates excito-neurotoxicity via microglial clearance of damaged neurons and antioxidant enzyme heme oxygenase-1 expression.

Noda M, Doi Y, Liang J, Kawanokuchi J, Sonobe Y, Takeuchi H, Mizuno T, Suzumura A.

J Biol Chem. 2016 Jul 1;291(27):14388. doi: 10.1074/jbc.A110.169839. No abstract available.

18.

Interleukin-25 expressed by brain capillary endothelial cells maintains blood-brain barrier function in a protein kinase Cϵ-dependent manner.

Sonobe Y, Takeuchi H, Kataoka K, Li H, Jin S, Mimuro M, Hashizume Y, Sano Y, Kanda T, Mizuno T, Suzumura A.

J Biol Chem. 2016 Jun 10;291(24):12573. doi: 10.1074/jbc.A109.025940. No abstract available.

19.

Corrigendum to "Glutamate induces neurotrophic factor production from microglia via protein kinase C pathway" [Brain Research 1322 (2010) 8-23].

Liang J, Takeuchi H, Jin S, Noda M, Li H, Doi Y, Kawanokuchi J, Sonobe Y, Mizuno T, Suzumura A.

Brain Res. 2016 Aug 1;1644:306-307. doi: 10.1016/j.brainres.2016.04.001. Epub 2016 Apr 5. No abstract available.

PMID:
27079835
20.

Conditioned Medium from the Stem Cells of Human Exfoliated Deciduous Teeth Ameliorates Experimental Autoimmune Encephalomyelitis.

Shimojima C, Takeuchi H, Jin S, Parajuli B, Hattori H, Suzumura A, Hibi H, Ueda M, Yamamoto A.

J Immunol. 2016 May 15;196(10):4164-71. doi: 10.4049/jimmunol.1501457. Epub 2016 Apr 6.

21.

Neuroprotective potential of molecular hydrogen against perinatal brain injury via suppression of activated microglia.

Imai K, Kotani T, Tsuda H, Mano Y, Nakano T, Ushida T, Li H, Miki R, Sumigama S, Iwase A, Hirakawa A, Ohno K, Toyokuni S, Takeuchi H, Mizuno T, Suzumura A, Kikkawa F.

Free Radic Biol Med. 2016 Feb;91:154-63. doi: 10.1016/j.freeradbiomed.2015.12.015. Epub 2015 Dec 22.

PMID:
26709014
22.

[Microglia in neuroimmunological disorders].

Suzumura A.

Nihon Rinsho. 2015 Sep;73 Suppl 7:66-72. Japanese. No abstract available.

PMID:
26480682
23.

CCL11 enhances excitotoxic neuronal death by producing reactive oxygen species in microglia.

Parajuli B, Horiuchi H, Mizuno T, Takeuchi H, Suzumura A.

Glia. 2015 Dec;63(12):2274-84. doi: 10.1002/glia.22892. Epub 2015 Jul 17.

PMID:
26184677
24.

Ganglioside GD3 Enhances Invasiveness of Gliomas by Forming a Complex with Platelet-derived Growth Factor Receptor α and Yes Kinase.

Ohkawa Y, Momota H, Kato A, Hashimoto N, Tsuda Y, Kotani N, Honke K, Suzumura A, Furukawa K, Ohmi Y, Natsume A, Wakabayashi T, Furukawa K.

J Biol Chem. 2015 Jun 26;290(26):16043-58. doi: 10.1074/jbc.M114.635755. Epub 2015 May 4.

25.

Interleukin-19 acts as a negative autocrine regulator of activated microglia.

Horiuchi H, Parajuli B, Wang Y, Azuma YT, Mizuno T, Takeuchi H, Suzumura A.

PLoS One. 2015 Mar 20;10(3):e0118640. doi: 10.1371/journal.pone.0118640. eCollection 2015.

26.

Secreted ectodomain of sialic acid-binding Ig-like lectin-9 and monocyte chemoattractant protein-1 promote recovery after rat spinal cord injury by altering macrophage polarity.

Matsubara K, Matsushita Y, Sakai K, Kano F, Kondo M, Noda M, Hashimoto N, Imagama S, Ishiguro N, Suzumura A, Ueda M, Furukawa K, Yamamoto A.

J Neurosci. 2015 Feb 11;35(6):2452-64. doi: 10.1523/JNEUROSCI.4088-14.2015.

27.

[Microglia in neurodegenerative disorders and neuroinflammation].

Suzumura A.

Rinsho Shinkeigaku. 2014;54(12):1119-21. doi: 10.5692/clinicalneurol.54.1119. Review. Japanese.

PMID:
25672725
28.

Interleukin-34 restores blood-brain barrier integrity by upregulating tight junction proteins in endothelial cells.

Jin S, Sonobe Y, Kawanokuchi J, Horiuchi H, Cheng Y, Wang Y, Mizuno T, Takeuchi H, Suzumura A.

PLoS One. 2014 Dec 23;9(12):e115981. doi: 10.1371/journal.pone.0115981. eCollection 2014.

29.

Interleukin-1β induces blood-brain barrier disruption by downregulating Sonic hedgehog in astrocytes.

Wang Y, Jin S, Sonobe Y, Cheng Y, Horiuchi H, Parajuli B, Kawanokuchi J, Mizuno T, Takeuchi H, Suzumura A.

PLoS One. 2014 Oct 14;9(10):e110024. doi: 10.1371/journal.pone.0110024. eCollection 2014.

30.

Gap junctions and hemichannels composed of connexins: potential therapeutic targets for neurodegenerative diseases.

Takeuchi H, Suzumura A.

Front Cell Neurosci. 2014 Sep 2;8:189. doi: 10.3389/fncel.2014.00189. eCollection 2014. Review.

31.

Granulocyte-colony stimulating factor attenuates oligomeric amyloid β neurotoxicity by activation of neprilysin.

Doi Y, Takeuchi H, Mizoguchi H, Fukumoto K, Horiuchi H, Jin S, Kawanokuchi J, Parajuli B, Sonobe Y, Mizuno T, Suzumura A.

PLoS One. 2014 Jul 25;9(7):e103458. doi: 10.1371/journal.pone.0103458. eCollection 2014.

32.

Evidence for aberrant astrocyte hemichannel activity in Juvenile Neuronal Ceroid Lipofuscinosis (JNCL).

Burkovetskaya M, Karpuk N, Xiong J, Bosch M, Boska MD, Takeuchi H, Suzumura A, Kielian T.

PLoS One. 2014 Apr 15;9(4):e95023. doi: 10.1371/journal.pone.0095023. eCollection 2014.

33.

FGF-2 released from degenerating neurons exerts microglial-induced neuroprotection via FGFR3-ERK signaling pathway.

Noda M, Takii K, Parajuli B, Kawanokuchi J, Sonobe Y, Takeuchi H, Mizuno T, Suzumura A.

J Neuroinflammation. 2014 Apr 16;11:76. doi: 10.1186/1742-2094-11-76.

34.

Fingolimod increases brain-derived neurotrophic factor levels and ameliorates amyloid β-induced memory impairment.

Fukumoto K, Mizoguchi H, Takeuchi H, Horiuchi H, Kawanokuchi J, Jin S, Mizuno T, Suzumura A.

Behav Brain Res. 2014 Jul 15;268:88-93. doi: 10.1016/j.bbr.2014.03.046. Epub 2014 Apr 5.

PMID:
24713151
35.

Sirtuin 1 attenuates oxidative stress via upregulation of superoxide dismutase 2 and catalase in astrocytes.

Cheng Y, Takeuchi H, Sonobe Y, Jin S, Wang Y, Horiuchi H, Parajuli B, Kawanokuchi J, Mizuno T, Suzumura A.

J Neuroimmunol. 2014 Apr 15;269(1-2):38-43. doi: 10.1016/j.jneuroim.2014.02.001. Epub 2014 Feb 12.

PMID:
24565075
36.

Oligomeric amyloid β induces IL-1β processing via production of ROS: implication in Alzheimer's disease.

Parajuli B, Sonobe Y, Horiuchi H, Takeuchi H, Mizuno T, Suzumura A.

Cell Death Dis. 2013 Dec 19;4:e975. doi: 10.1038/cddis.2013.503.

37.

Ablation of keratan sulfate accelerates early phase pathogenesis of ALS.

Hirano K, Ohgomori T, Kobayashi K, Tanaka F, Matsumoto T, Natori T, Matsuyama Y, Uchimura K, Sakamoto K, Takeuchi H, Hirakawa A, Suzumura A, Sobue G, Ishiguro N, Imagama S, Kadomatsu K.

PLoS One. 2013 Jun 25;8(6):e66969. doi: 10.1371/journal.pone.0066969. Print 2013.

38.

[Microglia in pathophysiology of neuroimmunological disorders].

Suzumura A.

Nihon Rinsho. 2013 May;71(5):801-6. Review. Japanese.

PMID:
23777085
39.

Fingolimod phosphate attenuates oligomeric amyloid β-induced neurotoxicity via increased brain-derived neurotrophic factor expression in neurons.

Doi Y, Takeuchi H, Horiuchi H, Hanyu T, Kawanokuchi J, Jin S, Parajuli B, Sonobe Y, Mizuno T, Suzumura A.

PLoS One. 2013 Apr 12;8(4):e61988. doi: 10.1371/journal.pone.0061988. Print 2013.

40.

Neuron-microglia interaction in neuroinflammation.

Suzumura A.

Curr Protein Pept Sci. 2013 Feb;14(1):16-20. Review.

PMID:
23544747
41.

Minocycline selectively inhibits M1 polarization of microglia.

Kobayashi K, Imagama S, Ohgomori T, Hirano K, Uchimura K, Sakamoto K, Hirakawa A, Takeuchi H, Suzumura A, Ishiguro N, Kadomatsu K.

Cell Death Dis. 2013 Mar 7;4:e525. doi: 10.1038/cddis.2013.54.

42.

Fingolimod phosphate promotes the neuroprotective effects of microglia.

Noda H, Takeuchi H, Mizuno T, Suzumura A.

J Neuroimmunol. 2013 Mar 15;256(1-2):13-8. doi: 10.1016/j.jneuroim.2012.12.005. Epub 2013 Jan 3.

PMID:
23290828
43.

GM-CSF increases LPS-induced production of proinflammatory mediators via upregulation of TLR4 and CD14 in murine microglia.

Parajuli B, Sonobe Y, Kawanokuchi J, Doi Y, Noda M, Takeuchi H, Mizuno T, Suzumura A.

J Neuroinflammation. 2012 Dec 13;9:268. doi: 10.1186/1742-2094-9-268.

44.

The neurotoxic effect of astrocytes activated with toll-like receptor ligands.

Ma D, Jin S, Li E, Doi Y, Parajuli B, Noda M, Sonobe Y, Mizuno T, Suzumura A.

J Neuroimmunol. 2013 Jan 15;254(1-2):10-8. doi: 10.1016/j.jneuroim.2012.08.010. Epub 2012 Sep 19.

PMID:
22999806
45.

TGF-β induced by interleukin-34-stimulated microglia regulates microglial proliferation and attenuates oligomeric amyloid β neurotoxicity.

Ma D, Doi Y, Jin S, Li E, Sonobe Y, Takeuchi H, Mizuno T, Suzumura A.

Neurosci Lett. 2012 Oct 31;529(1):86-91. doi: 10.1016/j.neulet.2012.08.071. Epub 2012 Sep 7.

PMID:
22985514
46.

Exposure to 1-bromopropane induces microglial changes and oxidative stress in the rat cerebellum.

Subramanian K, Mohideen SS, Suzumura A, Asai N, Murakumo Y, Takahashi M, Jin S, Zhang L, Huang Z, Ichihara S, Kitoh J, Ichihara G.

Toxicology. 2012 Dec 8;302(1):18-24. doi: 10.1016/j.tox.2012.07.006. Epub 2012 Jul 21.

PMID:
22824114
47.

The neuroprotective effects of milk fat globule-EGF factor 8 against oligomeric amyloid β toxicity.

Li E, Noda M, Doi Y, Parajuli B, Kawanokuchi J, Sonobe Y, Takeuchi H, Mizuno T, Suzumura A.

J Neuroinflammation. 2012 Jun 28;9:148. doi: 10.1186/1742-2094-9-148.

48.

Sweepers in the CNS: Microglial Migration and Phagocytosis in the Alzheimer Disease Pathogenesis.

Noda M, Suzumura A.

Int J Alzheimers Dis. 2012;2012:891087. doi: 10.1155/2012/891087. Epub 2012 May 14.

49.

Midkine inhibits inducible regulatory T cell differentiation by suppressing the development of tolerogenic dendritic cells.

Sonobe Y, Li H, Jin S, Kishida S, Kadomatsu K, Takeuchi H, Mizuno T, Suzumura A.

J Immunol. 2012 Mar 15;188(6):2602-11. doi: 10.4049/jimmunol.1102346. Epub 2012 Feb 8.

50.

Immunoglobulin G(1) immune complex upregulates interferon-γ-induced nitric oxide production via ERK1/2 activation in murine microglia.

Parajuli B, Sonobe Y, Kawanokuchi J, Doi Y, Noda M, Takeuchi H, Mizuno T, Suzumura A.

J Neuroimmunol. 2012 Mar;244(1-2):57-62. doi: 10.1016/j.jneuroim.2012.01.004. Epub 2012 Feb 4.

PMID:
22306300

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