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Items: 27

1.

Novel role of erythropoietin in proliferative diabetic retinopathy.

Takagi H, Watanabe D, Suzuma K, Kurimoto M, Suzuma I, Ohashi H, Ojima T, Murakami T.

Diabetes Res Clin Pract. 2007 Sep;77 Suppl 1:S62-4. Epub 2007 May 3.

PMID:
17481772
2.

Cyclic stretch-induced reactive oxygen species generation enhances apoptosis in retinal pericytes through c-jun NH2-terminal kinase activation.

Suzuma I, Murakami T, Suzuma K, Kaneto H, Watanabe D, Ojima T, Honda Y, Takagi H, Yoshimura N.

Hypertension. 2007 Feb;49(2):347-54. Epub 2006 Dec 11.

PMID:
17159082
3.

EphrinA1 inhibits vascular endothelial growth factor-induced intracellular signaling and suppresses retinal neovascularization and blood-retinal barrier breakdown.

Ojima T, Takagi H, Suzuma K, Oh H, Suzuma I, Ohashi H, Watanabe D, Suganami E, Murakami T, Kurimoto M, Honda Y, Yoshimura N.

Am J Pathol. 2006 Jan;168(1):331-9.

4.

Erythropoietin as a retinal angiogenic factor in proliferative diabetic retinopathy.

Watanabe D, Suzuma K, Matsui S, Kurimoto M, Kiryu J, Kita M, Suzuma I, Ohashi H, Ojima T, Murakami T, Kobayashi T, Masuda S, Nagao M, Yoshimura N, Takagi H.

N Engl J Med. 2005 Aug 25;353(8):782-92.

5.

Angiopoietin-1 attenuates H2O2-induced SEK1/JNK phosphorylation through the phosphatidylinositol 3-kinase/Akt pathway in vascular endothelial cells.

Murakami T, Takagi H, Suzuma K, Suzuma I, Ohashi H, Watanabe D, Ojima T, Suganami E, Kurimoto M, Kaneto H, Honda Y, Yoshimura N.

J Biol Chem. 2005 Sep 9;280(36):31841-9. Epub 2005 Jul 6.

6.

Vitreous levels of angiopoietin 2 and vascular endothelial growth factor in patients with proliferative diabetic retinopathy.

Watanabe D, Suzuma K, Suzuma I, Ohashi H, Ojima T, Kurimoto M, Murakami T, Kimura T, Takagi H.

Am J Ophthalmol. 2005 Mar;139(3):476-81.

PMID:
15767056
7.

Insulin receptor substrate 2 is essential for maturation and survival of photoreceptor cells.

Yi X, Schubert M, Peachey NS, Suzuma K, Burks DJ, Kushner JA, Suzuma I, Cahill C, Flint CL, Dow MA, Leshan RL, King GL, White MF.

J Neurosci. 2005 Feb 2;25(5):1240-8.

8.

Leptin stimulates ischemia-induced retinal neovascularization: possible role of vascular endothelial growth factor expressed in retinal endothelial cells.

Suganami E, Takagi H, Ohashi H, Suzuma K, Suzuma I, Oh H, Watanabe D, Ojima T, Suganami T, Fujio Y, Nakao K, Ogawa Y, Yoshimura N.

Diabetes. 2004 Sep;53(9):2443-8.

9.

Transcription factor Ets-1 mediates ischemia- and vascular endothelial growth factor-dependent retinal neovascularization.

Watanabe D, Takagi H, Suzuma K, Suzuma I, Oh H, Ohashi H, Kemmochi S, Uemura A, Ojima T, Suganami E, Miyamoto N, Sato Y, Honda Y.

Am J Pathol. 2004 May;164(5):1827-35.

10.

Phosphatidylinositol 3-kinase/Akt regulates angiotensin II-induced inhibition of apoptosis in microvascular endothelial cells by governing survivin expression and suppression of caspase-3 activity.

Ohashi H, Takagi H, Oh H, Suzuma K, Suzuma I, Miyamoto N, Uemura A, Watanabe D, Murakami T, Sugaya T, Fukamizu A, Honda Y.

Circ Res. 2004 Apr 2;94(6):785-93. Epub 2004 Feb 12.

PMID:
14963002
11.

Characterization of multiple signaling pathways of insulin in the regulation of vascular endothelial growth factor expression in vascular cells and angiogenesis.

Jiang ZY, He Z, King BL, Kuroki T, Opland DM, Suzuma K, Suzuma I, Ueki K, Kulkarni RN, Kahn CR, King GL.

J Biol Chem. 2003 Aug 22;278(34):31964-71. Epub 2003 May 29.

12.

Suppression of Fas-FasL-induced endothelial cell apoptosis prevents diabetic blood-retinal barrier breakdown in a model of streptozotocin-induced diabetes.

Joussen AM, Poulaki V, Mitsiades N, Cai WY, Suzuma I, Pak J, Ju ST, Rook SL, Esser P, Mitsiades CS, Kirchhof B, Adamis AP, Aiello LP.

FASEB J. 2003 Jan;17(1):76-8. Epub 2002 Nov 15.

PMID:
12475915
13.

Expression of estrogen receptor in the choroidal neovascular membranes in highly myopic eyes.

Kobayashi K, Mandai M, Suzuma I, Kobayashi H, Okinami S.

Retina. 2002 Aug;22(4):418-22.

PMID:
12172107
14.

Contrasting effect of estrogen on VEGF induction under different oxygen status and its role in murine ROP.

Miyamoto N, Mandai M, Takagi H, Suzuma I, Suzuma K, Koyama S, Otani A, Oh H, Honda Y.

Invest Ophthalmol Vis Sci. 2002 Jun;43(6):2007-14.

PMID:
12037012
15.

Pigment epithelium-derived factor suppresses ischemia-induced retinal neovascularization and VEGF-induced migration and growth.

Duh EJ, Yang HS, Suzuma I, Miyagi M, Youngman E, Mori K, Katai M, Yan L, Suzuma K, West K, Davarya S, Tong P, Gehlbach P, Pearlman J, Crabb JW, Aiello LP, Campochiaro PA, Zack DJ.

Invest Ophthalmol Vis Sci. 2002 Mar;43(3):821-9.

PMID:
11867604
16.
17.

Decreased cardiac expression of vascular endothelial growth factor and its receptors in insulin-resistant and diabetic States: a possible explanation for impaired collateral formation in cardiac tissue.

Chou E, Suzuma I, Way KJ, Opland D, Clermont AC, Naruse K, Suzuma K, Bowling NL, Vlahos CJ, Aiello LP, King GL.

Circulation. 2002 Jan 22;105(3):373-9.

PMID:
11804995
20.
21.

Retinal expression, regulation, and functional bioactivity of prostacyclin-stimulating factor.

Hata Y, Clermont A, Yamauchi T, Pierce EA, Suzuma I, Kagokawa H, Yoshikawa H, Robinson GS, Ishibashi T, Hashimoto T, Umeda F, Bursell SE, Aiello LP.

J Clin Invest. 2000 Aug;106(4):541-50.

22.

17 Beta-estradiol increases VEGF receptor-2 and promotes DNA synthesis in retinal microvascular endothelial cells.

Suzuma I, Mandai M, Takagi H, Suzuma K, Otani A, Oh H, Kobayashi K, Honda Y.

Invest Ophthalmol Vis Sci. 1999 Aug;40(9):2122-9.

PMID:
10440269
23.

Estrogen protects against cellular infiltration by reducing the expressions of E-selectin and IL-6 in endotoxin-induced uveitis.

Miyamoto N, Mandai M, Suzuma I, Suzuma K, Kobayashi K, Honda Y.

J Immunol. 1999 Jul 1;163(1):374-9.

24.

Quantitative analysis of diabetic macular edema after scatter laser photocoagulation with the scanning retinal thickness analyzer.

Tsujikawa A, Kiryu J, Dong J, Yasukawa T, Suzuma I, Takagi H, Ogura Y.

Retina. 1999;19(1):59-64.

PMID:
10048375
25.

Increased expression of KDR/Flk-1 (VEGFR-2) in murine model of ischemia-induced retinal neovascularization.

Suzuma K, Takagi H, Otani A, Suzuma I, Honda Y.

Microvasc Res. 1998 Nov;56(3):183-91.

PMID:
9828156
26.

Contribution of E-selectin to cellular infiltration during endotoxin-induced uveitis.

Suzuma I, Mandai M, Suzuma K, Ishida K, Tojo SJ, Honda Y.

Invest Ophthalmol Vis Sci. 1998 Aug;39(9):1620-30.

PMID:
9699551
27.

Quantitative analysis of foveal retinal thickness in diabetic retinopathy with the scanning retinal thickness analyzer.

Yasukawa T, Kiryu J, Tsujikawa A, Dong J, Suzuma I, Takagi H, Ogura Y.

Retina. 1998;18(2):150-5.

PMID:
9564696

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