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Items: 14


LSD1 activation promotes inducible EMT programs and modulates the tumour microenvironment in breast cancer.

Boulding T, McCuaig RD, Tan A, Hardy K, Wu F, Dunn J, Kalimutho M, Sutton CR, Forwood JK, Bert AG, Goodall GJ, Malik L, Yip D, Dahlstrom JE, Zafar A, Khanna KK, Rao S.

Sci Rep. 2018 Jan 8;8(1):73. doi: 10.1038/s41598-017-17913-x.


Priming of transcriptional memory responses via the chromatin accessibility landscape in T cells.

Tu WJ, Hardy K, Sutton CR, McCuaig R, Li J, Dunn J, Tan A, Brezar V, Morris M, Denyer G, Lee SK, Turner SJ, Seddiki N, Smith C, Khanna R, Rao S.

Sci Rep. 2017 Mar 20;7:44825. doi: 10.1038/srep44825.


Nuclear PKC-θ facilitates rapid transcriptional responses in human memory CD4+ T cells through p65 and H2B phosphorylation.

Li J, Hardy K, Phetsouphanh C, Tu WJ, Sutcliffe EL, McCuaig R, Sutton CR, Zafar A, Munier CM, Zaunders JJ, Xu Y, Theodoratos A, Tan A, Lim PS, Knaute T, Masch A, Zerweck J, Brezar V, Milburn PJ, Dunn J, Casarotto MG, Turner SJ, Seddiki N, Kelleher AD, Rao S.

J Cell Sci. 2016 Jun 15;129(12):2448-61. doi: 10.1242/jcs.181248. Epub 2016 May 5.


Identification of chromatin accessibility domains in human breast cancer stem cells.

Hardy K, Wu F, Tu W, Zafar A, Boulding T, McCuaig R, Sutton CR, Theodoratos A, Rao S.

Nucleus. 2016;7(1):50-67. doi: 10.1080/19491034.2016.1150392. Epub 2016 Mar 10.


Differential Roles for DUSP Family Members in Epithelial-to-Mesenchymal Transition and Cancer Stem Cell Regulation in Breast Cancer.

Boulding T, Wu F, McCuaig R, Dunn J, Sutton CR, Hardy K, Tu W, Bullman A, Yip D, Dahlstrom JE, Rao S.

PLoS One. 2016 Feb 9;11(2):e0148065. doi: 10.1371/journal.pone.0148065. eCollection 2016.


Three-dimensional hip and knee kinematics during walking, running, and single-limb drop landing in females with and without genu valgum.

Barrios JA, Heitkamp CA, Smith BP, Sturgeon MM, Suckow DW, Sutton CR.

Clin Biomech (Bristol, Avon). 2016 Jan;31:7-11. doi: 10.1016/j.clinbiomech.2015.10.008. Epub 2015 Oct 17.


Protein kinase C in the immune system: from signalling to chromatin regulation.

Lim PS, Sutton CR, Rao S.

Immunology. 2015 Dec;146(4):508-22. doi: 10.1111/imm.12510. Epub 2015 Oct 6. Review.


Mutant PIK3CA accelerates HER2-driven transgenic mammary tumors and induces resistance to combinations of anti-HER2 therapies.

Hanker AB, Pfefferle AD, Balko JM, Kuba MG, Young CD, Sánchez V, Sutton CR, Cheng H, Perou CM, Zhao JJ, Cook RS, Arteaga CL.

Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):14372-7. doi: 10.1073/pnas.1303204110. Epub 2013 Aug 12.


An antibody that locks HER3 in the inactive conformation inhibits tumor growth driven by HER2 or neuregulin.

Garner AP, Bialucha CU, Sprague ER, Garrett JT, Sheng Q, Li S, Sineshchekova O, Saxena P, Sutton CR, Chen D, Chen Y, Wang H, Liang J, Das R, Mosher R, Gu J, Huang A, Haubst N, Zehetmeier C, Haberl M, Elis W, Kunz C, Heidt AB, Herlihy K, Murtie J, Schuller A, Arteaga CL, Sellers WR, Ettenberg SA.

Cancer Res. 2013 Oct 1;73(19):6024-35. doi: 10.1158/0008-5472.CAN-13-1198. Epub 2013 Aug 8.


Combination of antibody that inhibits ligand-independent HER3 dimerization and a p110α inhibitor potently blocks PI3K signaling and growth of HER2+ breast cancers.

Garrett JT, Sutton CR, Kurupi R, Bialucha CU, Ettenberg SA, Collins SD, Sheng Q, Wallweber J, Defazio-Eli L, Arteaga CL.

Cancer Res. 2013 Oct 1;73(19):6013-23. doi: 10.1158/0008-5472.CAN-13-1191. Epub 2013 Aug 5.


Dual blockade of HER2 in HER2-overexpressing tumor cells does not completely eliminate HER3 function.

Garrett JT, Sutton CR, Kuba MG, Cook RS, Arteaga CL.

Clin Cancer Res. 2013 Feb 1;19(3):610-9. doi: 10.1158/1078-0432.CCR-12-2024. Epub 2012 Dec 5.


Inhibition of leucine decarboxylase by thiol-binding reagents.


Arch Biochem Biophys. 1962 Feb;96:360-70. No abstract available.


Decarboxylation of neutral amino acids in Proteus vulgaris.


J Gen Microbiol. 1957 Dec;17(3):602-19. No abstract available.

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