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Items: 22


NRF2 regulates core and stabilizing circadian clock loops, coupling redox and timekeeping in Mus musculus.

Wible RS, Ramanathan C, Sutter CH, Olesen KM, Kensler TW, Liu AC, Sutter TR.

Elife. 2018 Feb 26;7. pii: e31656. doi: 10.7554/eLife.31656.


Pharmacogenomics of Chemically Distinct Classes of Keap1-Nrf2 Activators Identify Common and Unique Gene, Protein, and Pathway Responses In Vivo.

Wible RS, Tran QT, Fathima S, Sutter CH, Kensler TW, Sutter TR.

Mol Pharmacol. 2018 Apr;93(4):297-308. doi: 10.1124/mol.117.110262. Epub 2018 Jan 24.


Role of EGF receptor ligands in TCDD-induced EGFR down-regulation and cellular proliferation.

Campion CM, Leon Carrion S, Mamidanna G, Sutter CH, Sutter TR, Cole JA.

Chem Biol Interact. 2016 Jun 25;253:38-47. doi: 10.1016/j.cbi.2016.04.031. Epub 2016 Apr 23.


Effects of in utero exposure of C57BL/6J mice to 2,3,7,8-tetrachlorodibenzo-p-dioxin on epidermal permeability barrier development and function.

Muenyi CS, Carrion SL, Jones LA, Kennedy LH, Slominski AT, Sutter CH, Sutter TR.

Environ Health Perspect. 2014 Oct;122(10):1052-8. doi: 10.1289/ehp.1308045. Epub 2014 Jun 6.


Combined treatment with sodium butyrate and PD153035 enhances keratinocyte differentiation.

Leon Carrion S, Sutter CH, Sutter TR.

Exp Dermatol. 2014 Mar;23(3):211-4. doi: 10.1111/exd.12333.


2,3,7,8-Tetrachlorodibenzo-p-dioxin-mediated production of reactive oxygen species is an essential step in the mechanism of action to accelerate human keratinocyte differentiation.

Kennedy LH, Sutter CH, Leon Carrion S, Tran QT, Bodreddigari S, Kensicki E, Mohney RP, Sutter TR.

Toxicol Sci. 2013 Mar;132(1):235-49. doi: 10.1093/toxsci/kfs325. Epub 2012 Nov 14.


EGFR regulation of epidermal barrier function.

Tran QT, Kennedy LH, Leon Carrion S, Bodreddigari S, Goodwin SB, Sutter CH, Sutter TR.

Physiol Genomics. 2012 Apr 15;44(8):455-69. doi: 10.1152/physiolgenomics.00176.2011. Epub 2012 Mar 6.


2,3,7,8-Tetrachlorodibenzo-p-dioxin increases the expression of genes in the human epidermal differentiation complex and accelerates epidermal barrier formation.

Sutter CH, Bodreddigari S, Campion C, Wible RS, Sutter TR.

Toxicol Sci. 2011 Nov;124(1):128-37. doi: 10.1093/toxsci/kfr205. Epub 2011 Aug 11.


Yap1 activation by H2O2 or thiol-reactive chemicals elicits distinct adaptive gene responses.

Ouyang X, Tran QT, Goodwin S, Wible RS, Sutter CH, Sutter TR.

Free Radic Biol Med. 2011 Jan 1;50(1):1-13. doi: 10.1016/j.freeradbiomed.2010.10.697. Epub 2010 Nov 6.


Analysis of the CYP1A1 mRNA dose-response in human keratinocytes indicates that relative potencies of dioxins, furans, and PCBs are species and congener specific.

Sutter CH, Bodreddigari S, Sutter TR, Carlson EA, Silkworth JB.

Toxicol Sci. 2010 Dec;118(2):704-15. doi: 10.1093/toxsci/kfq262. Epub 2010 Sep 6.


Stability of RNA structural motifs and its influence on editing efficiency by adenosine deaminases.

Phan V, Thomas A, Malasri K, Sutter CH.

Int J Bioinform Res Appl. 2010;6(1):21-36.


EGF receptor signaling blocks aryl hydrocarbon receptor-mediated transcription and cell differentiation in human epidermal keratinocytes.

Sutter CH, Yin H, Li Y, Mammen JS, Bodreddigari S, Stevens G, Cole JA, Sutter TR.

Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4266-71. doi: 10.1073/pnas.0900874106. Epub 2009 Mar 2. Erratum in: Proc Natl Acad Sci U S A. 2009 Jun 2;106(22):9121.


Transgenic expression of aflatoxin aldehyde reductase (AKR7A1) modulates aflatoxin B1 metabolism but not hepatic carcinogenesis in the rat.

Roebuck BD, Johnson DN, Sutter CH, Egner PA, Scholl PF, Friesen MD, Baumgartner KJ, Ware NM, Bodreddigari S, Groopman JD, Kensler TW, Sutter TR.

Toxicol Sci. 2009 May;109(1):41-9. doi: 10.1093/toxsci/kfp003. Epub 2009 Jan 23.


Chemical genomics of cancer chemopreventive dithiolethiones.

Tran QT, Xu L, Phan V, Goodwin SB, Rahman M, Jin VX, Sutter CH, Roebuck BD, Kensler TW, George EO, Sutter TR.

Carcinogenesis. 2009 Mar;30(3):480-6. doi: 10.1093/carcin/bgn292. Epub 2009 Jan 6.


Protection against aflatoxin B1-induced cytotoxicity by expression of the cloned aflatoxin B1-aldehyde reductases rat AKR7A1 and human AKR7A3.

Bodreddigari S, Jones LK, Egner PA, Groopman JD, Sutter CH, Roebuck BD, Guengerich FP, Kensler TW, Sutter TR.

Chem Res Toxicol. 2008 May;21(5):1134-42. doi: 10.1021/tx7004458. Epub 2008 Apr 15.


CYP1B1 is not a major determinant of the disposition of aromatase inhibitors in epithelial cells of invasive ductal carcinoma.

Rahman M, Lax SF, Sutter CH, Tran QT, Stevens GL, Emmert GL, Russo J, Santen RJ, Sutter TR.

Drug Metab Dispos. 2008 May;36(5):963-70. doi: 10.1124/dmd.107.018960. Epub 2008 Feb 6.


Uncertainties related to the assignment of a toxic equivalency factor for 1,2,3,4,6,7,8,9-octachlorodibenzo-p-dioxin.

Sutter CH, Rahman M, Sutter TR.

Regul Toxicol Pharmacol. 2006 Apr;44(3):219-25. Epub 2006 Feb 3. Review.


3H-1,2-dithiole-3-thione targets nuclear factor kappaB to block expression of inducible nitric-oxide synthase, prevents hypotension, and improves survival in endotoxemic rats.

Karuri AR, Huang Y, Bodreddigari S, Sutter CH, Roebuck BD, Kensler TW, Sutter TR.

J Pharmacol Exp Ther. 2006 Apr;317(1):61-7. Epub 2005 Dec 21.


Multiple comparisons model-based clustering and ternary pattern tree numerical display of gene response to treatment: procedure and application to the preclinical evaluation of chemopreventive agents.

Sutter TR, He XR, Dimitrov P, Xu L, Narasimhan G, George EO, Sutter CH, Grubbs C, Savory R, Stephan-Gueldner M, Kreder D, Taylor MJ, Lubet R, Patterson TA, Kensler TW.

Mol Cancer Ther. 2002 Dec;1(14):1283-92.


Genotyping human cytochrome: P450 1B1 variants.

Sutter CH, Qian Z, Hong YP, Mammen JS, Strickland PT, Sutter TR.

Methods Enzymol. 2002;357:53-8. No abstract available.


Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha.

Ravi R, Mookerjee B, Bhujwalla ZM, Sutter CH, Artemov D, Zeng Q, Dillehay LE, Madan A, Semenza GL, Bedi A.

Genes Dev. 2000 Jan 1;14(1):34-44.

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