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Items: 22

1.

New evaluation of trunk movement and balance during walking in COPD patients by a triaxial accelerometer.

Terui Y, Iwakura M, Suto E, Kawagoshi A, Sugawara K, Takahashi H, Hasegawa K, Uemura S, Satake M, Shioya T.

Int J Chron Obstruct Pulmon Dis. 2018 Dec 7;13:3957-3962. doi: 10.2147/COPD.S184212. eCollection 2018.

2.

Lung-restricted inhibition of Janus kinase 1 is effective in rodent models of asthma.

Dengler HS, Wu X, Peng I, Rinderknecht CH, Kwon Y, Suto E, Kohli PB, Liimatta M, Barrett K, Lloyd J, Cain G, Briggs M, Addo S, Salmon G, Ubhayakar S, Deshmukh G, Shahidi-Latham SK, Quiason-Huynh CM, Jackman J, Liu J, Ray NC, Goodacre SC, Johnson A, McKenzie BS, Lee WP, Zak M, Kenny JR, Ghilardi N.

Sci Transl Med. 2018 Nov 21;10(468). pii: eaao2151. doi: 10.1126/scitranslmed.aao2151.

PMID:
30463918
3.

Anterior cruciate ligament-derived mesenchymal stromal cells have a propensity to differentiate into the ligament lineage.

Ogata Y, Mabuchi Y, Shinoda K, Horiike Y, Mizuno M, Otabe K, Suto EG, Suzuki N, Sekiya I, Akazawa C.

Regen Ther. 2018 Jan 23;8:20-28. doi: 10.1016/j.reth.2017.12.001. eCollection 2018 Jun.

4.

Scaffold-Hopping Approach To Discover Potent, Selective, and Efficacious Inhibitors of NF-κB Inducing Kinase.

Blaquiere N, Castanedo GM, Burch JD, Berezhkovskiy LM, Brightbill H, Brown S, Chan C, Chiang PC, Crawford JJ, Dong T, Fan P, Feng J, Ghilardi N, Godemann R, Gogol E, Grabbe A, Hole AJ, Hu B, Hymowitz SG, Alaoui Ismaili MH, Le H, Lee P, Lee W, Lin X, Liu N, McEwan PA, McKenzie B, Silvestre HL, Suto E, Sujatha-Bhaskar S, Wu G, Wu LC, Zhang Y, Zhong Z, Staben ST.

J Med Chem. 2018 Aug 9;61(15):6801-6813. doi: 10.1021/acs.jmedchem.8b00678. Epub 2018 Jul 24.

PMID:
29940120
5.

Evaluation of gait symmetry using a tri-axial accelerometer in stroke patients.

Terui Y, Suto E, Konno Y, Kubota K, Iwakura M, Satou M, Nitta S, Hasegawa K, Satake M, Shioya T.

NeuroRehabilitation. 2018;42(2):173-180. doi: 10.3233/NRE-172235.

PMID:
29562555
6.

NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus.

Brightbill HD, Suto E, Blaquiere N, Ramamoorthi N, Sujatha-Bhaskar S, Gogol EB, Castanedo GM, Jackson BT, Kwon YC, Haller S, Lesch J, Bents K, Everett C, Kohli PB, Linge S, Christian L, Barrett K, Jaochico A, Berezhkovskiy LM, Fan PW, Modrusan Z, Veliz K, Townsend MJ, DeVoss J, Johnson AR, Godemann R, Lee WP, Austin CD, McKenzie BS, Hackney JA, Crawford JJ, Staben ST, Alaoui Ismaili MH, Wu LC, Ghilardi N.

Nat Commun. 2018 Jan 12;9(1):179. doi: 10.1038/s41467-017-02672-0.

7.

Progranulin deficiency causes impairment of autophagy and TDP-43 accumulation.

Chang MC, Srinivasan K, Friedman BA, Suto E, Modrusan Z, Lee WP, Kaminker JS, Hansen DV, Sheng M.

J Exp Med. 2017 Sep 4;214(9):2611-2628. doi: 10.1084/jem.20160999. Epub 2017 Aug 4.

8.

The Ox40/Ox40 Ligand Pathway Promotes Pathogenic Th Cell Responses, Plasmablast Accumulation, and Lupus Nephritis in NZB/W F1 Mice.

Sitrin J, Suto E, Wuster A, Eastham-Anderson J, Kim JM, Austin CD, Lee WP, Behrens TW.

J Immunol. 2017 Aug 15;199(4):1238-1249. doi: 10.4049/jimmunol.1700608. Epub 2017 Jul 10.

9.

Prospectively isolated mesenchymal stem/stromal cells are enriched in the CD73+ population and exhibit efficacy after transplantation.

Suto EG, Mabuchi Y, Suzuki N, Suzuki K, Ogata Y, Taguchi M, Muneta T, Sekiya I, Akazawa C.

Sci Rep. 2017 Jul 6;7(1):4838. doi: 10.1038/s41598-017-05099-1.

10.

Btk-specific inhibition blocks pathogenic plasma cell signatures and myeloid cell-associated damage in IFNα-driven lupus nephritis.

Katewa A, Wang Y, Hackney JA, Huang T, Suto E, Ramamoorthi N, Austin CD, Bremer M, Chen JZ, Crawford JJ, Currie KS, Blomgren P, DeVoss J, DiPaolo JA, Hau J, Johnson A, Lesch J, DeForge LE, Lin Z, Liimatta M, Lubach JW, McVay S, Modrusan Z, Nguyen A, Poon C, Wang J, Liu L, Lee WP, Wong H, Young WB, Townsend MJ, Reif K.

JCI Insight. 2017 Apr 6;2(7):e90111. doi: 10.1172/jci.insight.90111.

11.

Combined blockade of the IL-13 and IL-33 pathways leads to a greater inhibition of type 2 inflammation over inhibition of either pathway alone.

Ramirez-Carrozzi V, Sambandam A, Zhou M, Yan D, Kang J, Wu X, Suto E, Baca M, Austin C, Xu M, Lee W, Pappu R.

J Allergy Clin Immunol. 2017 Feb;139(2):705-708.e6. doi: 10.1016/j.jaci.2016.08.026. Epub 2016 Sep 30. No abstract available.

PMID:
27697499
12.

Inhibition of the kinase ITK in a mouse model of asthma reduces cell death and fails to inhibit the inflammatory response.

Sun Y, Peng I, Webster JD, Suto E, Lesch J, Wu X, Senger K, Francis G, Barrett K, Collier JL, Burch JD, Zhou M, Chen Y, Chan C, Eastham-Anderson J, Ngu H, Li O, Staton T, Havnar C, Jaochico A, Jackman J, Jeet S, Riol-Blanco L, Wu LC, Choy DF, Arron JR, McKenzie BS, Ghilardi N, Ismaili MH, Pei Z, DeVoss J, Austin CD, Lee WP, Zarrin AA.

Sci Signal. 2015 Dec 1;8(405):ra122. doi: 10.1126/scisignal.aab0949.

PMID:
26628680
13.

Conditional Deletion of NF-κB-Inducing Kinase (NIK) in Adult Mice Disrupts Mature B Cell Survival and Activation.

Brightbill HD, Jackman JK, Suto E, Kennedy H, Jones C 3rd, Chalasani S, Lin Z, Tam L, Roose-Girma M, Balazs M, Austin CD, Lee WP, Wu LC.

J Immunol. 2015 Aug 1;195(3):953-64. doi: 10.4049/jimmunol.1401514. Epub 2015 Jun 26.

14.

Autoimmunity-associated protein tyrosine phosphatase PEP negatively regulates IFN-α receptor signaling.

Holmes DA, Suto E, Lee WP, Ou Q, Gong Q, Smith HR, Caplazi P, Chan AC.

J Exp Med. 2015 Jun 29;212(7):1081-93. doi: 10.1084/jem.20142130. Epub 2015 Jun 15.

15.

Purified Human Synovium Mesenchymal Stem Cells as a Good Resource for Cartilage Regeneration.

Ogata Y, Mabuchi Y, Yoshida M, Suto EG, Suzuki N, Muneta T, Sekiya I, Akazawa C.

PLoS One. 2015 Jun 8;10(6):e0129096. doi: 10.1371/journal.pone.0129096. eCollection 2015.

16.

Dual B cell immunotherapy is superior to individual anti-CD20 depletion or BAFF blockade in murine models of spontaneous or accelerated lupus.

Lin W, Seshasayee D, Lee WP, Caplazi P, McVay S, Suto E, Nguyen A, Lin Z, Sun Y, DeForge L, Balazs M, Martin F, Zarrin AA.

Arthritis Rheumatol. 2015 Jan;67(1):215-24. doi: 10.1002/art.38907.

17.

Development and preclinical characterization of a humanized antibody targeting CXCL12.

Zhong C, Wang J, Li B, Xiang H, Ultsch M, Coons M, Wong T, Chiang NY, Clark S, Clark R, Quintana L, Gribling P, Suto E, Barck K, Corpuz R, Yao J, Takkar R, Lee WP, Damico-Beyer LA, Carano RD, Adams C, Kelley RF, Wang W, Ferrara N.

Clin Cancer Res. 2013 Aug 15;19(16):4433-45. doi: 10.1158/1078-0432.CCR-13-0943. Epub 2013 Jun 28.

18.

CRIg mediates early Kupffer cell responses to adenovirus.

He JQ, Katschke KJ Jr, Gribling P, Suto E, Lee WP, Diehl L, Eastham-Anderson J, Ponakala A, Komuves L, Egen JG, van Lookeren Campagne M.

J Leukoc Biol. 2013 Feb;93(2):301-6. doi: 10.1189/jlb.0612311. Epub 2012 Dec 5.

PMID:
23225913
19.

Equilibrative nucleoside transporter 3 deficiency perturbs lysosome function and macrophage homeostasis.

Hsu CL, Lin W, Seshasayee D, Chen YH, Ding X, Lin Z, Suto E, Huang Z, Lee WP, Park H, Xu M, Sun M, Rangell L, Lutman JL, Ulufatu S, Stefanich E, Chalouni C, Sagolla M, Diehl L, Fielder P, Dean B, Balazs M, Martin F.

Science. 2012 Jan 6;335(6064):89-92. doi: 10.1126/science.1213682. Epub 2011 Dec 15.

20.

In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation.

Seshasayee D, Lee WP, Zhou M, Shu J, Suto E, Zhang J, Diehl L, Austin CD, Meng YG, Tan M, Bullens SL, Seeber S, Fuentes ME, Labrijn AF, Graus YM, Miller LA, Schelegle ES, Hyde DM, Wu LC, Hymowitz SG, Martin F.

J Clin Invest. 2007 Dec;117(12):3868-78.

21.

Anti-BR3 antibodies: a new class of B-cell immunotherapy combining cellular depletion and survival blockade.

Lin WY, Gong Q, Seshasayee D, Lin Z, Ou Q, Ye S, Suto E, Shu J, Lee WP, Lee CW, Fuh G, Leabman M, Iyer S, Howell K, Gelzleichter T, Beyer J, Danilenko D, Yeh S, DeForge LE, Ebens A, Thompson JS, Ambrose C, Balazs M, Starovasnik MA, Martin F.

Blood. 2007 Dec 1;110(12):3959-67. Epub 2007 Aug 8.

22.

Prevention of aerobic spoilage of maize silage by a genetically modified killer yeast, Kluyveromyces lactis, defective in the ability to grow on lactic acid.

Kitamoto HK, Hasebe A, Ohmomo S, Suto EG, Muraki M, Iimura Y.

Appl Environ Microbiol. 1999 Oct;65(10):4697-700.

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