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Supratherapeutic Psychotropic Drug Levels in the Emergency Department and Their Association with Delirium Duration: A Preliminary Study.

Han JH, Chen A, Vasilevskis EE, Schnelle JF, Ely EW, Chandrasekhar R, Morrison RD, Ryan TP, Daniels JS, Sutherland JJ, Simmons SF.

J Am Geriatr Soc. 2019 Sep 10. doi: 10.1111/jgs.16156. [Epub ahead of print]


Sexual abuse disclosure among incarcerated female adolescents and young adults.

Malloy LC, Sutherland JE, Cauffman E.

Child Abuse Negl. 2019 Sep 5:104147. doi: 10.1016/j.chiabu.2019.104147. [Epub ahead of print]


Role of Postoperative Patient-Reported Outcomes to Predict Ankle Arthroplasty and Arthrodesis Revision.

Desai S, Sutherland JM, Younger A, Penner M, Veljkovic A, Yusuf F, Wing K.

Foot Ankle Int. 2019 Aug 28:1071100719869204. doi: 10.1177/1071100719869204. [Epub ahead of print]


Analysis of cellular and soluble profiles in QuantiFERON nonconverters, converters, and reverters in the Gambia.

Medawar L, Tukiman HM, Mbayo G, Donkor S, Owolabi O, Sutherland JS.

Immun Inflamm Dis. 2019 Aug 20. doi: 10.1002/iid3.269. [Epub ahead of print]


Changes in transcript, metabolite and antibody reactivity during the early protective immune response in humans to Mycobacterium tuberculosis infection.

Weiner J, Domaszewska T, Donkor S, Kaufmann SHE, Hill PC, Sutherland JS.

Clin Infect Dis. 2019 Aug 15. pii: ciz785. doi: 10.1093/cid/ciz785. [Epub ahead of print]


Effects of nano-hydroxyapatite on the formation of biofilms by Streptococcus mutans in two different media.

Park M, Sutherland JB, Rafii F.

Arch Oral Biol. 2019 Jul 21;107:104484. doi: 10.1016/j.archoralbio.2019.104484. [Epub ahead of print]


Advances in human primordial follicle activation and premature ovarian insufficiency.

Ford E, Beckett EL, Roman S, McLaughlin EA, Sutherland J.

Reproduction. 2019 Aug 1. pii: REP-19-0201.R2. doi: 10.1530/REP-19-0201. [Epub ahead of print] Review.


Correction: Discovery and validation of a prognostic proteomic signature for tuberculosis progression: A prospective cohort study.

Penn-Nicholson A, Hraha T, Thompson EG, Sterling D, Mbandi SK, Wall KM, Fisher M, Suliman S, Shankar S, Hanekom WA, Janjic N, Hatherill M, Kaufmann SHE, Sutherland J, Walzl G, De Groote MA, Ochsner U, Zak DE, Scriba TJ; ACS and GC6–74 cohort study groups.

PLoS Med. 2019 Jul 18;16(7):e1002880. doi: 10.1371/journal.pmed.1002880. eCollection 2019 Jul.


Sequence analysis of capnography waveform abnormalities during nurse-administered procedural sedation and analgesia in the cardiac catheterization laboratory.

Conway A, Collins P, Chang K, Mafeld S, Sutherland J, Fingleton J.

Sci Rep. 2019 Jul 15;9(1):10214. doi: 10.1038/s41598-019-46751-2.


Health and Quality of Life Outcomes Among Patients Undergoing Surgery for End-Stage Ankle Arthritis.

Rajapakshe S, Sutherland JM, Wing K, Crump T, Liu G, Penner M, Younger A, Veljkovic A, Redfern K.

Foot Ankle Int. 2019 Jun 19:1071100719856888. doi: 10.1177/1071100719856888. [Epub ahead of print]


Evaluation of the monocyte activation test for the safety testing of meningococcal B vaccine Bexsero: A collaborative study.

Studholme L, Sutherland J, Desai T, Hockley J, Care R, Nordgren IK, Vipond C; Collaborative Study Group.

Vaccine. 2019 Jun 27;37(29):3761-3769. doi: 10.1016/j.vaccine.2018.05.073. Epub 2018 Dec 10.


Development and validation of a monocyte activation test for the control/safety testing of an OMV-based meningococcal B vaccine.

Vipond C, Sutherland J, Nordgren K, Kemp G, Heath A, Care R, Studholme L.

Vaccine. 2019 Jun 27;37(29):3747-3753. doi: 10.1016/j.vaccine.2018.06.038. Epub 2018 Dec 10.


A Cost-Utility Study of Laparoscopic Cholecystectomy for the Treatment of Symptomatic Gallstones.

Sutherland JM, Mok J, Liu G, Karimuddin A, Crump T.

J Gastrointest Surg. 2019 May 29. doi: 10.1007/s11605-019-04268-z. [Epub ahead of print]


The small non-coding RNA profile of mouse oocytes is modified during aging.

Mihalas BP, Camlin NJ, Xavier MJ, Peters AE, Holt JE, Sutherland JM, McLaughlin EA, Eamens AL, Nixon B.

Aging (Albany NY). 2019 May 24;11(10):2968-2997. doi: 10.18632/aging.101947.


Proteostasis: the network behind the networks.

Barrio R, Sutherland JD.

Semin Cell Dev Biol. 2019 May 9. pii: S1084-9521(19)30091-6. doi: 10.1016/j.semcdb.2019.05.005. [Epub ahead of print] No abstract available.


The impact of comorbid depression in chronic rhinosinusitis on post-operative sino-nasal quality of life and pain following endoscopic sinus surgery.

Ospina J, Liu G, Crump T, Sutherland JM, Janjua A.

J Otolaryngol Head Neck Surg. 2019 Apr 30;48(1):18. doi: 10.1186/s40463-019-0340-0.


A Novel Open Access Web Portal for Integrating Mechanistic and Toxicogenomic Study Results.

Sutherland JJ, Stevens JL, Johnson K, Elango N, Webster YW, Mills BJ, Robertson DH.

Toxicol Sci. 2019 Aug 1;170(2):296-309. doi: 10.1093/toxsci/kfz101.


Characterization of a potent dominant negative mutant variant of Rad51 in Ustilago maydis.

Sutherland JH, Holloman WK.

DNA Repair (Amst). 2019 Jun;78:91-101. doi: 10.1016/j.dnarep.2019.04.003. Epub 2019 Apr 11.


Proteostasis: The network behind the networks.

Barrio R, Sutherland JD.

Semin Cell Dev Biol. 2019 Sep;93:97-99. doi: 10.1016/j.semcdb.2019.04.011. Epub 2019 Apr 21. No abstract available.


A prospective evaluation of the 'C.O.A.C.H.E.D.' cognitive aid for emergency defibrillation.

Coggins A, Nottingham C, Chin M, Warburton S, Han M, Murphy M, Sutherland J, Moore N.

Australas Emerg Care. 2018 Aug;21(3):81-86. doi: 10.1016/j.auec.2018.08.002. Epub 2018 Sep 10.


Discovery and validation of a prognostic proteomic signature for tuberculosis progression: A prospective cohort study.

Penn-Nicholson A, Hraha T, Thompson EG, Sterling D, Mbandi SK, Wall KM, Fisher M, Suliman S, Shankar S, Hanekom WA, Janjic N, Hatherill M, Kaufmann SHE, Sutherland J, Walzl G, De Groote MA, Ochsner U, Zak DE, Scriba TJ; ACS and GC6–74 cohort study groups.

PLoS Med. 2019 Apr 16;16(4):e1002781. doi: 10.1371/journal.pmed.1002781. eCollection 2019 Apr. Erratum in: PLoS Med. 2019 Jul 18;16(7):e1002880.


Immunometabolic Signatures Predict Risk of Progression to Active Tuberculosis and Disease Outcome.

Duffy FJ, Weiner J 3rd, Hansen S, Tabb DL, Suliman S, Thompson E, Maertzdorf J, Shankar S, Tromp G, Parida S, Dover D, Axthelm MK, Sutherland JS, Dockrell HM, Ottenhoff THM, Scriba TJ, Picker LJ, Walzl G, Kaufmann SHE, Zak DE; GC6-74 Consortium.

Front Immunol. 2019 Mar 22;10:527. doi: 10.3389/fimmu.2019.00527. eCollection 2019.


Discharge destination following hip fracture in Canada among previously community-dwelling older adults, 2004-2012: database study.

Beaupre L, Sobolev B, Guy P, Kim JD, Kuramoto L, Sheehan KJ, Sutherland JM, Harvey E, Morin SN; Canadian Collaborative Study of Hip Fractures.

Osteoporos Int. 2019 Jul;30(7):1383-1394. doi: 10.1007/s00198-019-04943-6. Epub 2019 Apr 1.


Prebiotic phosphorylation of 2-thiouridine provides either nucleotides or DNA building blocks via photoreduction.

Xu J, Green NJ, Gibard C, Krishnamurthy R, Sutherland JD.

Nat Chem. 2019 May;11(5):457-462. doi: 10.1038/s41557-019-0225-x. Epub 2019 Apr 1.


Predicting VMAT patient-specific QA results using a support vector classifier trained on treatment plan characteristics and linac QC metrics.

Granville DA, Sutherland JG, Belec JG, La Russa DJ.

Phys Med Biol. 2019 Apr 29;64(9):095017. doi: 10.1088/1361-6560/ab142e.


Charting a course for chemistry.

Aspuru-Guzik A, Baik MH, Balasubramanian S, Banerjee R, Bart S, Borduas-Dedekind N, Chang S, Chen P, Corminboeuf C, Coudert FX, Cronin L, Crudden C, Cuk T, Doyle AG, Fan C, Feng X, Freedman D, Furukawa S, Ghosh S, Glorius F, Jeffries-El M, Katsonis N, Li A, Linse SS, Marchesan S, Maulide N, Milo A, Narayan ARH, Naumov P, Nevado C, Nyokong T, Palacin R, Reid M, Robinson C, Robinson G, Sarpong R, Schindler C, Schlau-Cohen GS, Schmidt TW, Sessoli R, Shao-Horn Y, Sleiman H, Sutherland J, Taylor A, Tezcan A, Tortosa M, Walsh A, Watson AJB, Weckhuysen BM, Weiss E, Wilson D, Yam VW, Yang X, Ying JY, Yoon T, You SL, Zarbin AJG, Zhang H.

Nat Chem. 2019 Apr;11(4):286-294. doi: 10.1038/s41557-019-0236-7. No abstract available.


Nursing Home Length of Stay in 3 Canadian Health Regions: Temporal Trends, Jurisdictional Differences, and Associated Factors.

Hoben M, Chamberlain SA, Gruneir A, Knopp-Sihota JA, Sutherland JM, Poss JW, Doupe MB, Bergstrom V, Norton PG, Schalm C, McCarthy K, Kashuba K, Ackah F, Estabrooks CA.

J Am Med Dir Assoc. 2019 Sep;20(9):1121-1128. doi: 10.1016/j.jamda.2019.01.144. Epub 2019 Mar 14.


Minimally Important Difference in the Foot and Ankle Outcome Score Among Patients Undergoing Hallux Valgus Surgery.

Desai S, Peterson AC, Wing K, Younger A, Crump T, Liu G, Veljkovic A, Penner M, Sutherland JM.

Foot Ankle Int. 2019 Jun;40(6):694-701. doi: 10.1177/1071100719831392. Epub 2019 Mar 15.


Wait lists and adult general surgery: is there a socioeconomic dimension in Canada?

Sutherland JM, Kurzawa Z, Karimuddin A, Duncan K, Liu G, Crump T.

BMC Health Serv Res. 2019 Mar 13;19(1):161. doi: 10.1186/s12913-019-3981-9.


Safety evaluation of 2'-deoxy-2'-fluoro nucleotides in GalNAc-siRNA conjugates.

Janas MM, Zlatev I, Liu J, Jiang Y, Barros SA, Sutherland JE, Davis WP, Liu J, Brown CR, Liu X, Schlegel MK, Blair L, Zhang X, Das B, Tran C, Aluri K, Li J, Agarwal S, Indrakanti R, Charisse K, Nair J, Matsuda S, Rajeev KG, Zimmermann T, Sepp-Lorenzino L, Xu Y, Akinc A, Fitzgerald K, Vaishnaw AK, Smith PF, Manoharan M, Jadhav V, Wu JT, Maier MA.

Nucleic Acids Res. 2019 Apr 23;47(7):3306-3320. doi: 10.1093/nar/gkz140.


Using Ubiquitin Binders to Decipher the Ubiquitin Code.

Mattern M, Sutherland J, Kadimisetty K, Barrio R, Rodriguez MS.

Trends Biochem Sci. 2019 Jul;44(7):599-615. doi: 10.1016/j.tibs.2019.01.011. Epub 2019 Feb 25. Review.


Do preoperative patient-reported outcomes predict hospital length of stay for surgically-treated end-stage ankle osteoarthritis patients?

Sutherland JM, Rajapakshe S, Younger A, Crump T, Wing K, Liu G, Veljkovic A.

Foot Ankle Surg. 2019 Feb 2. pii: S1268-7731(18)30468-5. doi: 10.1016/j.fas.2019.01.008. [Epub ahead of print]


Length-Selective Synthesis of Acylglycerol-Phosphates through Energy-Dissipative Cycling.

Bonfio C, Caumes C, Duffy CD, Patel BH, Percivalle C, Tsanakopoulou M, Sutherland JD.

J Am Chem Soc. 2019 Mar 6;141(9):3934-3939. doi: 10.1021/jacs.8b12331. Epub 2019 Feb 22.


Investigation into the presence and functional significance of proinsulin C-peptide in the female germline†.

Martin JH, Aitken RJ, Bromfield EG, Cafe SL, Sutherland JM, Frost ER, Nixon B, Lord T.

Biol Reprod. 2019 May 1;100(5):1275-1289. doi: 10.1093/biolre/ioz008.


Do sulfate radicals really enable a non-enzymatic Krebs cycle precursor?

Sutherland J, Ritson D.

Nat Ecol Evol. 2019 Feb;3(2):138. doi: 10.1038/s41559-018-0791-0. No abstract available.


Changes in Mycobacterium tuberculosis-Specific Immunity With Influenza co-infection at Time of TB Diagnosis.

Mendy J, Jarju S, Heslop R, Bojang AL, Kampmann B, Sutherland JS.

Front Immunol. 2019 Jan 4;9:3093. doi: 10.3389/fimmu.2018.03093. eCollection 2018.


Assessment of Patient Medication Adherence, Medical Record Accuracy, and Medication Blood Concentrations for Prescription and Over-the-Counter Medications.

Sutherland JJ, Morrison RD, McNaughton CD, Daly TM, Milne SB, Daniels JS, Ryan TP.

JAMA Netw Open. 2018 Nov 2;1(7):e184196. doi: 10.1001/jamanetworkopen.2018.4196.


Development and characteristics of the Provincial Overdose Cohort in British Columbia, Canada.

MacDougall L, Smolina K, Otterstatter M, Zhao B, Chong M, Godfrey D, Mussavi-Rizi A, Sutherland J, Kuo M, Kendall P.

PLoS One. 2019 Jan 10;14(1):e0210129. doi: 10.1371/journal.pone.0210129. eCollection 2019.


Validation of the Ankle Osteoarthritis Scale Instrument for Preoperative Evaluation of End-Stage Ankle Arthritis Patients Using Item Response Theory.

Liu G, Peterson AC, Wing K, Crump T, Younger A, Penner M, Veljkovic A, Foggin H, Sutherland JM.

Foot Ankle Int. 2019 Apr;40(4):422-429. doi: 10.1177/1071100718818573. Epub 2019 Jan 10.


TB sequel: incidence, pathogenesis and risk factors of long-term medical and social sequelae of pulmonary TB - a study protocol.

Rachow A, Ivanova O, Wallis R, Charalambous S, Jani I, Bhatt N, Kampmann B, Sutherland J, Ntinginya NE, Evans D, Lönnroth K, Niemann S, Schaible UE, Geldmacher C, Sanne I, Hoelscher M, Churchyard G.

BMC Pulm Med. 2019 Jan 7;19(1):4. doi: 10.1186/s12890-018-0777-3.


U.S. Nurse Practitioner Beliefs About Routine HIV Screening: Predicting Behaviors.

Sutherland JL, Spencer GA.

J Assoc Nurses AIDS Care. 2019 May-Jun;30(3):270-278. doi: 10.1097/JNC.0000000000000014.


Assessing the learning needs of the multidisciplinary team on geriatric oncology and frailty.

Rittberg R, Sutherland J, Huynh E, Green S, Wiens A, Stirling M, Dawe DE.

J Geriatr Oncol. 2019 Sep;10(5):829-831. doi: 10.1016/j.jgo.2018.12.002. Epub 2018 Dec 26. No abstract available.


Impact of blending for direct potable reuse on premise plumbing microbial ecology and regrowth of opportunistic pathogens and antibiotic resistant bacteria.

Garner E, Inyang M, Garvey E, Parks J, Glover C, Grimaldi A, Dickenson E, Sutherland J, Salveson A, Edwards MA, Pruden A.

Water Res. 2019 Mar 15;151:75-86. doi: 10.1016/j.watres.2018.12.003. Epub 2018 Dec 11.


Cost-Utility Study of the Economics of Bunion Correction Surgery.

Sutherland JM, Mok J, Liu G, Crump T, Wing K, Younger A, Penner M, Veljkovic A.

Foot Ankle Int. 2019 Mar;40(3):336-342. doi: 10.1177/1071100718815663. Epub 2018 Dec 17.


Metabolite changes in blood predict the onset of tuberculosis.

Weiner J 3rd, Maertzdorf J, Sutherland JS, Duffy FJ, Thompson E, Suliman S, McEwen G, Thiel B, Parida SK, Zyla J, Hanekom WA, Mohney RP, Boom WH, Mayanja-Kizza H, Howe R, Dockrell HM, Ottenhoff THM, Scriba TJ, Zak DE, Walzl G, Kaufmann SHE; GC6-74 consortium.

Nat Commun. 2018 Dec 6;9(1):5208. doi: 10.1038/s41467-018-07635-7.


Operationalising a conceptual framework for a contiguous hospitalisation episode to study associations between surgical timing and death after first hip fracture: a Canadian observational study.

Sheehan KJ, Levy AR, Sobolev B, Guy P, Tang M, Kuramoto L, Sutherland JM, Beaupre L, Morin SN, Harvey E, Bradley N; Canadian Collaborative Study of Hip Fractures.

BMJ Open. 2018 Dec 6;8(12):e020372. doi: 10.1136/bmjopen-2017-020372.


Use of the Dental Electronic Health Record for Research: Assessing Demographic and Oral Health Characteristics Data for Clinic Patients.

Gordon SM, Camargo GA, Mejia GC, Sutherland JN.

J Dent Educ. 2018 Dec;82(12):1249-1257. doi: 10.21815/JDE.018.130.


International experiments with different models of allocating funds to facilitate integrated care: a scoping review protocol.

Khayatzadeh-Mahani A, Nolte E, Sutherland J, Forest PG.

BMJ Open. 2018 Nov 15;8(11):e021374. doi: 10.1136/bmjopen-2017-021374.


Characterisation of the NRF2 transcriptional network and its response to chemical insult in primary human hepatocytes: implications for prediction of drug-induced liver injury.

Copple IM, den Hollander W, Callegaro G, Mutter FE, Maggs JL, Schofield AL, Rainbow L, Fang Y, Sutherland JJ, Ellis EC, Ingelman-Sundberg M, Fenwick SW, Goldring CE, van de Water B, Stevens JL, Park BK.

Arch Toxicol. 2019 Feb;93(2):385-399. doi: 10.1007/s00204-018-2354-1. Epub 2018 Nov 13.


Complement Component C1q as Serum Biomarker to Detect Active Tuberculosis.

Lubbers R, Sutherland JS, Goletti D, de Paus RA, van Moorsel CHM, Veltkamp M, Vestjens SMT, Bos WJW, Petrone L, Del Nonno F, Bajema IM, Dijkman K, Verreck FAW, Walzl G, Gelderman KA, Groeneveld GH, Geluk A, Ottenhoff THM, Joosten SA, Trouw LA.

Front Immunol. 2018 Oct 23;9:2427. doi: 10.3389/fimmu.2018.02427. eCollection 2018.

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