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Items: 1 to 50 of 171

1.

Peripheral reduction of β-amyloid is sufficient to reduce brain β-amyloid: implications for Alzheimer's disease.

Sutcliffe JG, Hedlund PB, Thomas EA, Bloom FE, Hilbush BS.

J Neurosci Res. 2011 Jun;89(6):808-14. doi: 10.1002/jnr.22603. Epub 2011 Mar 3.

PMID:
21374699
2.

Differential gene expression in LPS/IFNgamma activated microglia and macrophages: in vitro versus in vivo.

Schmid CD, Melchior B, Masek K, Puntambekar SS, Danielson PE, Lo DD, Sutcliffe JG, Carson MJ.

J Neurochem. 2009 May;109 Suppl 1:117-25. doi: 10.1111/j.1471-4159.2009.05984.x. Erratum in: J Neurochem. 2009 Jun;109(6):1812.

3.

Normal human aging and early-stage schizophrenia share common molecular profiles.

Tang B, Chang WL, Lanigan CM, Dean B, Sutcliffe JG, Thomas EA.

Aging Cell. 2009 Jun;8(3):339-42. doi: 10.1111/j.1474-9726.2009.00468.x. Epub 2009 Feb 26.

4.

Molecular profiles of schizophrenia in the CNS at different stages of illness.

Narayan S, Tang B, Head SR, Gilmartin TJ, Sutcliffe JG, Dean B, Thomas EA.

Brain Res. 2008 Nov 6;1239:235-48. doi: 10.1016/j.brainres.2008.08.023. Epub 2008 Aug 16.

5.

Induction of Golli-MBP expression in CNS macrophages during acute LPS-induced CNS inflammation and experimental autoimmune encephalomyelitis (EAE).

Papenfuss TL, Thrash JC, Danielson PE, Foye PE, Hllbrush BS, Sutcliffe JG, Whitacre CC, Carson MJ.

ScientificWorldJournal. 2007 Nov 2;7:112-20.

6.

Glycolipid and ganglioside metabolism imbalances in Huntington's disease.

Desplats PA, Denny CA, Kass KE, Gilmartin T, Head SR, Sutcliffe JG, Seyfried TN, Thomas EA.

Neurobiol Dis. 2007 Sep;27(3):265-77. Epub 2007 May 22.

7.

Inactivation of the 5-HT(7) receptor partially blocks phencyclidine-induced disruption of prepulse inhibition.

Semenova S, Geyer MA, Sutcliffe JG, Markou A, Hedlund PB.

Biol Psychiatry. 2008 Jan 1;63(1):98-105. Epub 2007 May 24.

8.

The 5-HT7 receptor influences stereotypic behavior in a model of obsessive-compulsive disorder.

Hedlund PB, Sutcliffe JG.

Neurosci Lett. 2007 Mar 13;414(3):247-51. Epub 2007 Jan 11.

9.

New prospects and strategies for drug target discovery in neurodegenerative disorders.

Hilbush BS, Morrison JH, Young WG, Sutcliffe JG, Bloom FE.

NeuroRx. 2005 Oct;2(4):627-37. Review.

10.

Selective deficits in the expression of striatal-enriched mRNAs in Huntington's disease.

Desplats PA, Kass KE, Gilmartin T, Stanwood GD, Woodward EL, Head SR, Sutcliffe JG, Thomas EA.

J Neurochem. 2006 Feb;96(3):743-57. Epub 2006 Jan 9.

11.

The hypocretins and sleep.

de Lecea L, Sutcliffe JG.

FEBS J. 2005 Nov;272(22):5675-88. Review.

12.

5-HT7 receptor inhibition and inactivation induce antidepressantlike behavior and sleep pattern.

Hedlund PB, Huitron-Resendiz S, Henriksen SJ, Sutcliffe JG.

Biol Psychiatry. 2005 Nov 15;58(10):831-7. Epub 2005 Jul 14.

PMID:
16018977
13.

Regulation of alpha-synuclein expression in limbic and motor brain regions of morphine-treated mice.

Ziolkowska B, Gieryk A, Bilecki W, Wawrzczak-Bargiela A, Wedzony K, Chocyk A, Danielson PE, Thomas EA, Hilbush BS, Sutcliffe JG, Przewlocki R.

J Neurosci. 2005 May 18;25(20):4996-5003.

14.

Functional, molecular and pharmacological advances in 5-HT7 receptor research.

Hedlund PB, Sutcliffe JG.

Trends Pharmacol Sci. 2004 Sep;25(9):481-6. Review.

PMID:
15559250
15.

Not asleep, not quite awake.

Sutcliffe JG, de Lecea L.

Nat Med. 2004 Jul;10(7):673-4. No abstract available.

PMID:
15229508
16.

Mice lacking 5-HT receptors show specific impairments in contextual learning.

Roberts AJ, Krucker T, Levy CL, Slanina KA, Sutcliffe JG, Hedlund PB.

Eur J Neurosci. 2004 Apr;19(7):1913-22.

PMID:
15078565
17.

8-OH-DPAT acts on both 5-HT1A and 5-HT7 receptors to induce hypothermia in rodents.

Hedlund PB, Kelly L, Mazur C, Lovenberg T, Sutcliffe JG, Bonaventure P.

Eur J Pharmacol. 2004 Mar 8;487(1-3):125-32.

PMID:
15033384
18.
19.
20.

Antipsychotic drug treatment alters expression of mRNAs encoding lipid metabolism-related proteins.

Thomas EA, George RC, Danielson PE, Nelson PA, Warren AJ, Lo D, Sutcliffe JG.

Mol Psychiatry. 2003 Nov;8(12):983-93, 950.

PMID:
14647396
21.

Apolipoprotein D modulates arachidonic acid signaling in cultured cells: implications for psychiatric disorders.

Thomas EA, George RC, Sutcliffe JG.

Prostaglandins Leukot Essent Fatty Acids. 2003 Dec;69(6):421-7.

PMID:
14623496
22.

From pharmacotherapy to pathophysiology: emerging mechanisms of apolipoprotein D in psychiatric disorders.

Thomas EA, Copolov DL, Sutcliffe JG.

Curr Mol Med. 2003 Aug;3(5):408-18. Review.

PMID:
12942994
23.

Open system gene expression profiling and identification of novel genes for targeted vaccine delivery.

Lo D, Hilbush B, O'Mahony D, Sutcliffe JG.

Expert Rev Vaccines. 2002 Jun;1(1):95-100. Review.

PMID:
12908516
24.

Apolipoprotein D levels are elevated in prefrontal cortex of subjects with Alzheimer's disease: no relation to apolipoprotein E expression or genotype.

Thomas EA, Laws SM, Sutcliffe JG, Harper C, Dean B, McClean C, Masters C, Lautenschlager N, Gandy SE, Martins RN.

Biol Psychiatry. 2003 Jul 15;54(2):136-41.

PMID:
12873803
25.

Differences in neuroanatomical sites of apoD elevation discriminate between schizophrenia and bipolar disorder.

Thomas EA, Dean B, Scarr E, Copolov D, Sutcliffe JG.

Mol Psychiatry. 2003 Feb;8(2):167-75.

PMID:
12610649
26.

No hypothermic response to serotonin in 5-HT7 receptor knockout mice.

Hedlund PB, Danielson PE, Thomas EA, Slanina K, Carson MJ, Sutcliffe JG.

Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1375-80. Epub 2003 Jan 15.

27.

Searching for interferon-induced genes that inhibit hepatitis B virus replication in transgenic mouse hepatocytes.

Wieland SF, Vega RG, Müller R, Evans CF, Hilbush B, Guidotti LG, Sutcliffe JG, Schultz PG, Chisari FV.

J Virol. 2003 Jan;77(2):1227-36.

28.

Heterogeneous expression of the triggering receptor expressed on myeloid cells-2 on adult murine microglia.

Schmid CD, Sautkulis LN, Danielson PE, Cooper J, Hasel KW, Hilbush BS, Sutcliffe JG, Carson MJ.

J Neurochem. 2002 Dec;83(6):1309-20.

29.

The neurobiology of apolipoproteins in psychiatric disorders.

Sutcliffe JG, Thomas EA.

Mol Neurobiol. 2002 Oct-Dec;26(2-3):369-88. Review.

PMID:
12428765
30.

Hypocretins/orexins as integrators of physiological information: lessons from mutant animals.

de Lecea L, Sutcliffe JG, Fabre V.

Neuropeptides. 2002 Apr-Jun;36(2-3):85-95. Review.

PMID:
12359500
31.

Targeted disruption of RC3 reveals a calmodulin-based mechanism for regulating metaplasticity in the hippocampus.

Krucker T, Siggins GR, McNamara RK, Lindsley KA, Dao A, Allison DW, De Lecea L, Lovenberg TW, Sutcliffe JG, Gerendasy DD.

J Neurosci. 2002 Jul 1;22(13):5525-35.

32.

Hypocretin is an early member of the incretin gene family.

Alvarez CE, Sutcliffe JG.

Neurosci Lett. 2002 May 24;324(3):169-72.

PMID:
12009515
33.

Novel isoform of insulin receptor substrate p53/p58 is generated by alternative splicing in the CRIB/SH3-binding region.

Alvarez CE, Sutcliffe JG, Thomas EA.

J Biol Chem. 2002 Jul 5;277(27):24728-34. Epub 2002 May 2.

34.

The hypocretins: setting the arousal threshold.

Sutcliffe JG, de Lecea L.

Nat Rev Neurosci. 2002 May;3(5):339-49. Review.

PMID:
11988773
35.

Apolipoprotein D mRNA expression is elevated in PDAPP transgenic mice.

Thomas EA, Sautkulis LN, Criado JR, Games D, Sutcliffe JG.

J Neurochem. 2001 Dec;79(5):1059-64.

36.

Open-system approaches to gene expression in the CNS.

Sutcliffe JG.

J Neurosci. 2001 Nov 1;21(21):8306-9. Review. No abstract available.

37.

TOGA analysis of gene expression to accelerate target development.

Lo D, Hilbush B, Sutcliffe JG.

Eur J Pharm Sci. 2001 Oct;14(3):191-6.

PMID:
11576822
38.

Hypocretin (orexin) in the rat pineal gland: a central transmitter with effects on noradrenaline-induced release of melatonin.

Mikkelsen JD, Hauser F, deLecea L, Sutcliffe JG, Kilduff TS, Calgari C, Pévet P, Simonneaux V.

Eur J Neurosci. 2001 Aug;14(3):419-25.

PMID:
11553292
39.

Insulin receptor substrate protein p53 localization in rats suggests mechanism for specific polyglutamine neurodegeneration.

Thomas EA, Foye PE, Alvarez CE, Usui H, Sutcliffe JG.

Neurosci Lett. 2001 Aug 31;309(3):145-8.

PMID:
11514062
40.
41.

The hypocretins/orexins: novel hypothalamic neuropeptides involved in different physiological systems.

de Lecea L, Sutcliffe JG.

Cell Mol Life Sci. 1999 Oct 30;56(5-6):473-80. Review.

PMID:
11212299
42.

Clozapine increases apolipoprotein D expression in rodent brain: towards a mechanism for neuroleptic pharmacotherapy.

Thomas EA, Danielson PE, Nelson PA, Pribyl TM, Hilbush BS, Hasel KW, Sutcliffe JG.

J Neurochem. 2001 Feb;76(3):789-96.

43.

Immunohistochemical localization and biochemical characterization of hypocretin/orexin-related peptides in the central nervous system of the frog Rana ridibunda.

Galas L, Vaudry H, Braun B, Van Den Pol AN, De Lecea L, Sutcliffe JG, Chartrel N.

J Comp Neurol. 2001 Jan 8;429(2):242-52.

PMID:
11116217
44.

Hypocretin-1 modulates rapid eye movement sleep through activation of locus coeruleus neurons.

Bourgin P, Huitrón-Résendiz S, Spier AD, Fabre V, Morte B, Criado JR, Sutcliffe JG, Henriksen SJ, de Lecea L.

J Neurosci. 2000 Oct 15;20(20):7760-5.

45.

The hypocretins: excitatory neuromodulatory peptides for multiple homeostatic systems, including sleep and feeding.

Sutcliffe JG, de Lecea L.

J Neurosci Res. 2000 Oct 15;62(2):161-8. Review.

PMID:
11020209
46.

Pertussis toxin treatment prevents 5-HT(5a) receptor-mediated inhibition of cyclic AMP accumulation in rat C6 glioma cells.

Thomas EA, Matli JR, Hu JL, Carson MJ, Sutcliffe JG.

J Neurosci Res. 2000 Jul 1;61(1):75-81.

PMID:
10861802
47.
48.

Localization of olfactomedin-related glycoprotein isoform (BMZ) in the golgi apparatus of glomerular podocytes in rat kidneys.

Kondo D, Yamamoto T, Yaoita E, Danielson PE, Kobayashi H, Ohshiro K, Funaki H, Koyama Y, Fujinaka H, Kawasaki K, Sutcliffe JG, Arakawa M, Kihara I.

J Am Soc Nephrol. 2000 May;11(5):803-13.

49.

TOGA: an automated parsing technology for analyzing expression of nearly all genes.

Sutcliffe JG, Foye PE, Erlander MG, Hilbush BS, Bodzin LJ, Durham JT, Hasel KW.

Proc Natl Acad Sci U S A. 2000 Feb 29;97(5):1976-81.

50.

Allosteric regulation by oleamide of the binding properties of 5-hydroxytryptamine7 receptors.

Hedlund PB, Carson MJ, Sutcliffe JG, Thomas EA.

Biochem Pharmacol. 1999 Dec 1;58(11):1807-13.

PMID:
10571256

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