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Items: 1 to 50 of 127

1.

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.

Tin A, Marten J, Halperin Kuhns VL, Li Y, Wuttke M, Kirsten H, Sieber KB, Qiu C, Gorski M, Yu Z, Giri A, Sveinbjornsson G, Li M, Chu AY, Hoppmann A, O'Connor LJ, Prins B, Nutile T, Noce D, Akiyama M, Cocca M, Ghasemi S, van der Most PJ, Horn K, Xu Y, Fuchsberger C, Sedaghat S, Afaq S, Amin N, Ärnlöv J, Bakker SJL, Bansal N, Baptista D, Bergmann S, Biggs ML, Biino G, Boerwinkle E, Bottinger EP, Boutin TS, Brumat M, Burkhardt R, Campana E, Campbell A, Campbell H, Carroll RJ, Catamo E, Chambers JC, Ciullo M, Concas MP, Coresh J, Corre T, Cusi D, Felicita SC, de Borst MH, De Grandi A, de Mutsert R, de Vries APJ, Delgado G, Demirkan A, Devuyst O, Dittrich K, Eckardt KU, Ehret G, Endlich K, Evans MK, Gansevoort RT, Gasparini P, Giedraitis V, Gieger C, Girotto G, Gögele M, Gordon SD, Gudbjartsson DF, Gudnason V; German Chronic Kidney Disease Study, Haller T, Hamet P, Harris TB, Hayward C, Hicks AA, Hofer E, Holm H, Huang W, Hutri-Kähönen N, Hwang SJ, Ikram MA, Lewis RM, Ingelsson E, Jakobsdottir J, Jonsdottir I, Jonsson H, Joshi PK, Josyula NS, Jung B, Kähönen M, Kamatani Y, Kanai M, Kerr SM, Kiess W, Kleber ME, Koenig W, Kooner JS, Körner A, Kovacs P, Krämer BK, Kronenberg F, Kubo M, Kühnel B, La Bianca M, Lange LA, Lehne B, Lehtimäki T; Lifelines Cohort Study, Liu J, Loeffler M, Loos RJF, Lyytikäinen LP, Magi R, Mahajan A, Martin NG, März W, Mascalzoni D, Matsuda K, Meisinger C, Meitinger T, Metspalu A, Milaneschi Y; V. A. Million Veteran Program, O'Donnell CJ, Wilson OD, Gaziano JM, Mishra PP, Mohlke KL, Mononen N, Montgomery GW, Mook-Kanamori DO, Müller-Nurasyid M, Nadkarni GN, Nalls MA, Nauck M, Nikus K, Ning B, Nolte IM, Noordam R, O'Connell JR, Olafsson I, Padmanabhan S, Penninx BWJH, Perls T, Peters A, Pirastu M, Pirastu N, Pistis G, Polasek O, Ponte B, Porteous DJ, Poulain T, Preuss MH, Rabelink TJ, Raffield LM, Raitakari OT, Rettig R, Rheinberger M, Rice KM, Rizzi F, Robino A, Rudan I, Krajcoviechova A, Cifkova R, Rueedi R, Ruggiero D, Ryan KA, Saba Y, Salvi E, Schmidt H, Schmidt R, Shaffer CM, Smith AV, Smith BH, Spracklen CN, Strauch K, Stumvoll M, Sulem P, Tajuddin SM, Teren A, Thiery J, Thio CHL, Thorsteinsdottir U, Toniolo D, Tönjes A, Tremblay J, Uitterlinden AG, Vaccargiu S, van der Harst P, van Duijn CM, Verweij N, Völker U, Vollenweider P, Waeber G, Waldenberger M, Whitfield JB, Wild SH, Wilson JF, Yang Q, Zhang W, Zonderman AB, Bochud M, Wilson JG, Pendergrass SA, Ho K, Parsa A, Pramstaller PP, Psaty BM, Böger CA, Snieder H, Butterworth AS, Okada Y, Edwards TL, Stefansson K, Susztak K, Scholz M, Heid IM, Hung AM, Teumer A, Pattaro C, Woodward OM, Vitart V, Köttgen A.

Nat Genet. 2019 Oct 2. doi: 10.1038/s41588-019-0504-x. [Epub ahead of print]

PMID:
31578528
2.

Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen.

Salem RM, Todd JN, Sandholm N, Cole JB, Chen WM, Andrews D, Pezzolesi MG, McKeigue PM, Hiraki LT, Qiu C, Nair V, Di Liao C, Cao JJ, Valo E, Onengut-Gumuscu S, Smiles AM, McGurnaghan SJ, Haukka JK, Harjutsalo V, Brennan EP, van Zuydam N, Ahlqvist E, Doyle R, Ahluwalia TS, Lajer M, Hughes MF, Park J, Skupien J, Spiliopoulou A, Liu A, Menon R, Boustany-Kari CM, Kang HM, Nelson RG, Klein R, Klein BE, Lee KE, Gao X, Mauer M, Maestroni S, Caramori ML, de Boer IH, Miller RG, Guo J, Boright AP, Tregouet D, Gyorgy B, Snell-Bergeon JK, Maahs DM, Bull SB, Canty AJ, Palmer CNA, Stechemesser L, Paulweber B, Weitgasser R, Sokolovska J, Rovīte V, Pīrāgs V, Prakapiene E, Radzeviciene L, Verkauskiene R, Panduru NM, Groop LC, McCarthy MI, Gu HF, Möllsten A, Falhammar H, Brismar K, Martin F, Rossing P, Costacou T, Zerbini G, Marre M, Hadjadj S, McKnight AJ, Forsblom C, McKay G, Godson C, Maxwell AP, Kretzler M, Susztak K, Colhoun HM, Krolewski A, Paterson AD, Groop PH, Rich SS, Hirschhorn JN, Florez JC; SUMMIT Consortium, DCCT/EDIC Research Group, GENIE Consortium.

J Am Soc Nephrol. 2019 Oct;30(10):2000-2016. doi: 10.1681/ASN.2019030218. Epub 2019 Sep 19.

PMID:
31537649
3.

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.

Teumer A, Li Y, Ghasemi S, Prins BP, Wuttke M, Hermle T, Giri A, Sieber KB, Qiu C, Kirsten H, Tin A, Chu AY, Bansal N, Feitosa MF, Wang L, Chai JF, Cocca M, Fuchsberger C, Gorski M, Hoppmann A, Horn K, Li M, Marten J, Noce D, Nutile T, Sedaghat S, Sveinbjornsson G, Tayo BO, van der Most PJ, Xu Y, Yu Z, Gerstner L, Ärnlöv J, Bakker SJL, Baptista D, Biggs ML, Boerwinkle E, Brenner H, Burkhardt R, Carroll RJ, Chee ML, Chee ML, Chen M, Cheng CY, Cook JP, Coresh J, Corre T, Danesh J, de Borst MH, De Grandi A, de Mutsert R, de Vries APJ, Degenhardt F, Dittrich K, Divers J, Eckardt KU, Ehret G, Endlich K, Felix JF, Franco OH, Franke A, Freedman BI, Freitag-Wolf S, Gansevoort RT, Giedraitis V, Gögele M, Grundner-Culemann F, Gudbjartsson DF, Gudnason V, Hamet P, Harris TB, Hicks AA, Holm H, Foo VHX, Hwang SJ, Ikram MA, Ingelsson E, Jaddoe VWV, Jakobsdottir J, Josyula NS, Jung B, Kähönen M, Khor CC, Kiess W, Koenig W, Körner A, Kovacs P, Kramer H, Krämer BK, Kronenberg F, Lange LA, Langefeld CD, Lee JJ, Lehtimäki T, Lieb W, Lim SC, Lind L, Lindgren CM, Liu J, Loeffler M, Lyytikäinen LP, Mahajan A, Maranville JC, Mascalzoni D, McMullen B, Meisinger C, Meitinger T, Miliku K, Mook-Kanamori DO, Müller-Nurasyid M, Mychaleckyj JC, Nauck M, Nikus K, Ning B, Noordam R, Connell JO, Olafsson I, Palmer ND, Peters A, Podgornaia AI, Ponte B, Poulain T, Pramstaller PP, Rabelink TJ, Raffield LM, Reilly DF, Rettig R, Rheinberger M, Rice KM, Rivadeneira F, Runz H, Ryan KA, Sabanayagam C, Saum KU, Schöttker B, Shaffer CM, Shi Y, Smith AV, Strauch K, Stumvoll M, Sun BB, Szymczak S, Tai ES, Tan NYQ, Taylor KD, Teren A, Tham YC, Thiery J, Thio CHL, Thomsen H, Thorsteinsdottir U, Tönjes A, Tremblay J, Uitterlinden AG, van der Harst P, Verweij N, Vogelezang S, Völker U, Waldenberger M, Wang C, Wilson OD, Wong C, Wong TY, Yang Q, Yasuda M, Akilesh S, Bochud M, Böger CA, Devuyst O, Edwards TL, Ho K, Morris AP, Parsa A, Pendergrass SA, Psaty BM, Rotter JI, Stefansson K, Wilson JG, Susztak K, Snieder H, Heid IM, Scholz M, Butterworth AS, Hung AM, Pattaro C, Köttgen A.

Nat Commun. 2019 Sep 11;10(1):4130. doi: 10.1038/s41467-019-11576-0.

4.

Understanding the kidney one cell at a time.

Park J, Liu CL, Kim J, Susztak K.

Kidney Int. 2019 Oct;96(4):862-870. doi: 10.1016/j.kint.2019.03.035. Epub 2019 Jul 26. Review.

PMID:
31492507
5.

Mitochondrial Damage and Activation of the STING Pathway Lead to Renal Inflammation and Fibrosis.

Chung KW, Dhillon P, Huang S, Sheng X, Shrestha R, Qiu C, Kaufman BA, Park J, Pei L, Baur J, Palmer M, Susztak K.

Cell Metab. 2019 Oct 1;30(4):784-799.e5. doi: 10.1016/j.cmet.2019.08.003. Epub 2019 Aug 29.

PMID:
31474566
6.

Cytosine Methylation Studies in Patients with Diabetic Kidney Disease.

Aranyi T, Susztak K.

Curr Diab Rep. 2019 Aug 30;19(10):91. doi: 10.1007/s11892-019-1214-6. Review.

PMID:
31471761
7.

Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program.

Hellwege JN, Velez Edwards DR, Giri A, Qiu C, Park J, Torstenson ES, Keaton JM, Wilson OD, Robinson-Cohen C, Chung CP, Roumie CL, Klarin D, Damrauer SM, DuVall SL, Siew E, Akwo EA, Wuttke M, Gorski M, Li M, Li Y, Gaziano JM, Wilson PWF, Tsao PS, O'Donnell CJ, Kovesdy CP, Pattaro C, Köttgen A, Susztak K, Edwards TL, Hung AM.

Nat Commun. 2019 Aug 26;10(1):3842. doi: 10.1038/s41467-019-11704-w.

8.

Functional methylome analysis of human diabetic kidney disease.

Park J, Guan Y, Sheng X, Gluck C, Seasock MJ, Hakimi AA, Qiu C, Pullman J, Verma A, Li H, Palmer M, Susztak K.

JCI Insight. 2019 Jun 6;4(11). pii: 128886. doi: 10.1172/jci.insight.128886. eCollection 2019 Jun 6.

9.

Kidney cytosine methylation changes improve renal function decline estimation in patients with diabetic kidney disease.

Gluck C, Qiu C, Han SY, Palmer M, Park J, Ko YA, Guan Y, Sheng X, Hanson RL, Huang J, Chen Y, Park ASD, Izquierdo MC, Mantzaris I, Verma A, Pullman J, Li H, Susztak K.

Nat Commun. 2019 Jun 5;10(1):2461. doi: 10.1038/s41467-019-10378-8.

10.

Genomic Mismatch at LIMS1 Locus and Kidney Allograft Rejection.

Steers NJ, Li Y, Drace Z, D'Addario JA, Fischman C, Liu L, Xu K, Na YJ, Neugut YD, Zhang JY, Sterken R, Balderes O, Bradbury D, Ozturk N, Ozay F, Goswami S, Mehl K, Wold J, Jelloul FZ, Rohanizadegan M, Gillies CE, Vasilescu EM, Vlad G, Ko YA, Mohan S, Radhakrishnan J, Cohen DJ, Ratner LE, Scolari F, Susztak K, Sampson MG, Deaglio S, Caliskan Y, Barasch J, Courtney AE, Maxwell AP, McKnight AJ, Ionita-Laza I, Bakker SJL, Snieder H, de Borst MH, D'Agati V, Amoroso A, Gharavi AG, Kiryluk K.

N Engl J Med. 2019 May 16;380(20):1918-1928. doi: 10.1056/NEJMoa1803731.

PMID:
31091373
11.

Going from acute to chronic kidney injury with FoxO3.

Gu X, Raman A, Susztak K.

J Clin Invest. 2019 May 6;129(6):2192-2194. doi: 10.1172/JCI128985. eCollection 2019 May 6.

12.

FHL2 mediates podocyte Rac1 activation and foot process effacement in hypertensive nephropathy.

Li SY, Chu PH, Huang PH, Hsieh TH, Susztak K, Tarng DC.

Sci Rep. 2019 Apr 30;9(1):6693. doi: 10.1038/s41598-019-42328-1.

13.

A signature of circulating inflammatory proteins and development of end-stage renal disease in diabetes.

Niewczas MA, Pavkov ME, Skupien J, Smiles A, Md Dom ZI, Wilson JM, Park J, Nair V, Schlafly A, Saulnier PJ, Satake E, Simeone CA, Shah H, Qiu C, Looker HC, Fiorina P, Ware CF, Sun JK, Doria A, Kretzler M, Susztak K, Duffin KL, Nelson RG, Krolewski AS.

Nat Med. 2019 May;25(5):805-813. doi: 10.1038/s41591-019-0415-5. Epub 2019 Apr 22.

PMID:
31011203
14.

DNMT1 in Six2 Progenitor Cells Is Essential for Transposable Element Silencing and Kidney Development.

Li SY, Park J, Guan Y, Chung K, Shrestha R, Palmer MB, Susztak K.

J Am Soc Nephrol. 2019 Apr;30(4):594-609. doi: 10.1681/ASN.2018070687. Epub 2019 Mar 8.

PMID:
30850438
15.

The kidney transcriptome, from single cells to whole organs and back.

Huang S, Sheng X, Susztak K.

Curr Opin Nephrol Hypertens. 2019 May;28(3):219-226. doi: 10.1097/MNH.0000000000000495.

PMID:
30844884
16.

Long-Range Chromatin Interactions in the Kidney.

Guan Y, Liu H, Susztak K.

J Am Soc Nephrol. 2019 Feb 13. pii: ASN.2019010044. doi: 10.1681/ASN.2019010044. [Epub ahead of print] No abstract available.

PMID:
30760498
17.

Ascorbic acid-induced TET activation mitigates adverse hydroxymethylcytosine loss in renal cell carcinoma.

Shenoy N, Bhagat TD, Cheville J, Lohse C, Bhattacharyya S, Tischer A, Machha V, Gordon-Mitchell S, Choudhary G, Wong LF, Gross L, Ressigue E, Leibovich B, Boorjian SA, Steidl U, Wu X, Pradhan K, Gartrell B, Agarwal B, Pagliaro L, Suzuki M, Greally JM, Rakheja D, Thompson RH, Susztak K, Witzig T, Zou Y, Verma A.

J Clin Invest. 2019 Mar 4;130:1612-1625. doi: 10.1172/JCI98747. eCollection 2019 Mar 4.

18.

Bulk tissue cell type deconvolution with multi-subject single-cell expression reference.

Wang X, Park J, Susztak K, Zhang NR, Li M.

Nat Commun. 2019 Jan 22;10(1):380. doi: 10.1038/s41467-018-08023-x.

19.

Allele-specific RNA imaging shows that allelic imbalances can arise in tissues through transcriptional bursting.

Symmons O, Chang M, Mellis IA, Kalish JM, Park J, Suszták K, Bartolomei MS, Raj A.

PLoS Genet. 2019 Jan 9;15(1):e1007874. doi: 10.1371/journal.pgen.1007874. eCollection 2019 Jan.

20.

Associations of Fenofibrate Therapy With Incidence and Progression of CKD in Patients With Type 2 Diabetes.

Frazier R, Mehta R, Cai X, Lee J, Napoli S, Craven T, Tuazon J, Safdi A, Scialla J, Susztak K, Isakova T.

Kidney Int Rep. 2018 Sep 18;4(1):94-102. doi: 10.1016/j.ekir.2018.09.006. eCollection 2019 Jan.

21.

Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.

Giri A, Hellwege JN, Keaton JM, Park J, Qiu C, Warren HR, Torstenson ES, Kovesdy CP, Sun YV, Wilson OD, Robinson-Cohen C, Roumie CL, Chung CP, Birdwell KA, Damrauer SM, DuVall SL, Klarin D, Cho K, Wang Y, Evangelou E, Cabrera CP, Wain LV, Shrestha R, Mautz BS, Akwo EA, Sargurupremraj M, Debette S, Boehnke M, Scott LJ, Luan J, Zhao JH, Willems SM, Thériault S, Shah N, Oldmeadow C, Almgren P, Li-Gao R, Verweij N, Boutin TS, Mangino M, Ntalla I, Feofanova E, Surendran P, Cook JP, Karthikeyan S, Lahrouchi N, Liu C, Sepúlveda N, Richardson TG, Kraja A, Amouyel P, Farrall M, Poulter NR; Understanding Society Scientific Group; International Consortium for Blood Pressure; Blood Pressure-International Consortium of Exome Chip Studies, Laakso M, Zeggini E, Sever P, Scott RA, Langenberg C, Wareham NJ, Conen D, Palmer CNA, Attia J, Chasman DI, Ridker PM, Melander O, Mook-Kanamori DO, Harst PV, Cucca F, Schlessinger D, Hayward C, Spector TD, Jarvelin MR, Hennig BJ, Timpson NJ, Wei WQ, Smith JC, Xu Y, Matheny ME, Siew EE, Lindgren C, Herzig KH, Dedoussis G, Denny JC, Psaty BM, Howson JMM, Munroe PB, Newton-Cheh C, Caulfield MJ, Elliott P, Gaziano JM, Concato J, Wilson PWF, Tsao PS, Velez Edwards DR, Susztak K; Million Veteran Program, O'Donnell CJ, Hung AM, Edwards TL.

Nat Genet. 2019 Jan;51(1):51-62. doi: 10.1038/s41588-018-0303-9. Epub 2018 Dec 21.

22.

Renal compartment-specific genetic variation analyses identify new pathways in chronic kidney disease.

Qiu C, Huang S, Park J, Park Y, Ko YA, Seasock MJ, Bryer JS, Xu XX, Song WC, Palmer M, Hill J, Guarnieri P, Hawkins J, Boustany-Kari CM, Pullen SS, Brown CD, Susztak K.

Nat Med. 2018 Nov;24(11):1721-1731. doi: 10.1038/s41591-018-0194-4. Epub 2018 Oct 1.

23.

Epigenetics and Epigenomics: Implications for Diabetes and Obesity.

Rosen ED, Kaestner KH, Natarajan R, Patti ME, Sallari R, Sander M, Susztak K.

Diabetes. 2018 Oct;67(10):1923-1931. doi: 10.2337/db18-0537.

24.

Jagged1/Notch2 controls kidney fibrosis via Tfam-mediated metabolic reprogramming.

Huang S, Park J, Qiu C, Chung KW, Li SY, Sirin Y, Han SH, Taylor V, Zimber-Strobl U, Susztak K.

PLoS Biol. 2018 Sep 18;16(9):e2005233. doi: 10.1371/journal.pbio.2005233. eCollection 2018 Sep.

25.

APOL1: The Balance Imposed by Infection, Selection, and Kidney Disease.

Beckerman P, Susztak K.

Trends Mol Med. 2018 Aug;24(8):682-695. doi: 10.1016/j.molmed.2018.05.008. Epub 2018 Jun 7. Review.

26.

Genomic integration of ERRγ-HNF1β regulates renal bioenergetics and prevents chronic kidney disease.

Zhao J, Lupino K, Wilkins BJ, Qiu C, Liu J, Omura Y, Allred AL, McDonald C, Susztak K, Barish GD, Pei L.

Proc Natl Acad Sci U S A. 2018 May 22;115(21):E4910-E4919. doi: 10.1073/pnas.1804965115. Epub 2018 May 7.

27.

Cytosine methylation predicts renal function decline in American Indians.

Qiu C, Hanson RL, Fufaa G, Kobes S, Gluck C, Huang J, Chen Y, Raj D, Nelson RG, Knowler WC, Susztak K.

Kidney Int. 2018 Jun;93(6):1417-1431. doi: 10.1016/j.kint.2018.01.036. Epub 2018 Apr 27.

28.

Single-cell transcriptomics of the mouse kidney reveals potential cellular targets of kidney disease.

Park J, Shrestha R, Qiu C, Kondo A, Huang S, Werth M, Li M, Barasch J, Suszták K.

Science. 2018 May 18;360(6390):758-763. doi: 10.1126/science.aar2131. Epub 2018 Apr 5.

29.

Introduction: Systems Biology of Kidney Disease.

Sharma K, Susztak K, Pennathur S.

Semin Nephrol. 2018 Mar;38(2):99-100. doi: 10.1016/j.semnephrol.2018.02.001. No abstract available.

30.

The Role of Peroxisome Proliferator-Activated Receptor γ Coactivator 1α (PGC-1α) in Kidney Disease.

Li SY, Susztak K.

Semin Nephrol. 2018 Mar;38(2):121-126. doi: 10.1016/j.semnephrol.2018.01.003. Review.

31.

Screening Drugs for Kidney Disease: Targeting the Podocyte.

Bryer JS, Susztak K.

Cell Chem Biol. 2018 Feb 15;25(2):126-127. doi: 10.1016/j.chembiol.2018.01.018.

32.

Epigenome-wide association studies identify DNA methylation associated with kidney function.

Chu AY, Tin A, Schlosser P, Ko YA, Qiu C, Yao C, Joehanes R, Grams ME, Liang L, Gluck CA, Liu C, Coresh J, Hwang SJ, Levy D, Boerwinkle E, Pankow JS, Yang Q, Fornage M, Fox CS, Susztak K, Köttgen A.

Nat Commun. 2017 Nov 3;8(1):1286. doi: 10.1038/s41467-017-01297-7.

33.

Human Kidney Tubule-Specific Gene Expression Based Dissection of Chronic Kidney Disease Traits.

Beckerman P, Qiu C, Park J, Ledo N, Ko YA, Park AD, Han SY, Choi P, Palmer M, Susztak K.

EBioMedicine. 2017 Oct;24:267-276. doi: 10.1016/j.ebiom.2017.09.014. Epub 2017 Sep 18.

34.

In Utero Exposure to a High-Fat Diet Programs Hepatic Hypermethylation and Gene Dysregulation and Development of Metabolic Syndrome in Male Mice.

Seki Y, Suzuki M, Guo X, Glenn AS, Vuguin PM, Fiallo A, Du Q, Ko YA, Yu Y, Susztak K, Zheng D, Greally JM, Katz EB, Charron MJ.

Endocrinology. 2017 Sep 1;158(9):2860-2872. doi: 10.1210/en.2017-00334.

35.

APOL1 and Cardiovascular Disease: A Story in Evolution.

Bajaj A, Susztak K, Damrauer SM.

Arterioscler Thromb Vasc Biol. 2017 Sep;37(9):1587-1589. doi: 10.1161/ATVBAHA.117.309756. No abstract available.

36.

PGC-1α Protects from Notch-Induced Kidney Fibrosis Development.

Han SH, Wu MY, Nam BY, Park JT, Yoo TH, Kang SW, Park J, Chinga F, Li SY, Susztak K.

J Am Soc Nephrol. 2017 Nov;28(11):3312-3322. doi: 10.1681/ASN.2017020130. Epub 2017 Jul 27.

37.

A High Fat Diet During Pregnancy and Lactation Induces Cardiac and Renal Abnormalities in GLUT4 +/- Male Mice.

Kruse M, Fiallo A, Tao J, Susztak K, Amann K, Katz EB, Charron MJ.

Kidney Blood Press Res. 2017;42(3):468-482. doi: 10.1159/000479383. Epub 2017 Jul 27.

38.

Benign and tumor parenchyma metabolomic profiles affect compensatory renal growth in renal cell carcinoma surgical patients.

Rosenzweig B, Rubinstein ND, Reznik E, Shingarev R, Juluru K, Akin O, Hsieh JJ, Jaimes EA, Russo P, Susztak K, Coleman JA, Hakimi AA.

PLoS One. 2017 Jul 20;12(7):e0180350. doi: 10.1371/journal.pone.0180350. eCollection 2017.

39.

Increasing the level of peroxisome proliferator-activated receptor γ coactivator-1α in podocytes results in collapsing glomerulopathy.

Li SY, Park J, Qiu C, Han SH, Palmer MB, Arany Z, Susztak K.

JCI Insight. 2017 Jul 20;2(14). pii: 92930. doi: 10.1172/jci.insight.92930. eCollection 2017 Jul 20.

40.

Genetic-Variation-Driven Gene-Expression Changes Highlight Genes with Important Functions for Kidney Disease.

Ko YA, Yi H, Qiu C, Huang S, Park J, Ledo N, Köttgen A, Li H, Rader DJ, Pack MA, Brown CD, Susztak K.

Am J Hum Genet. 2017 Jun 1;100(6):940-953. doi: 10.1016/j.ajhg.2017.05.004.

41.

Kidney triglyceride accumulation in the fasted mouse is dependent upon serum free fatty acids.

Scerbo D, Son NH, Sirwi A, Zeng L, Sas KM, Cifarelli V, Schoiswohl G, Huggins LA, Gumaste N, Hu Y, Pennathur S, Abumrad NA, Kershaw EE, Hussain MM, Susztak K, Goldberg IJ.

J Lipid Res. 2017 Jun;58(6):1132-1142. doi: 10.1194/jlr.M074427. Epub 2017 Apr 12. Erratum in: J Lipid Res. 2017 Sep;58(9):1933.

42.

Therapeutics for APOL1 nephropathies: putting out the fire in the podocyte.

Heymann J, Winkler CA, Hoek M, Susztak K, Kopp JB.

Nephrol Dial Transplant. 2017 Jan 1;32(suppl_1):i65-i70. doi: 10.1093/ndt/gfw402. Review.

43.

Precision Medicine Approaches to Diabetic Kidney Disease: Tissue as an Issue.

Gluck C, Ko YA, Susztak K.

Curr Diab Rep. 2017 May;17(5):30. doi: 10.1007/s11892-017-0854-7. Review.

44.

Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice.

Beckerman P, Bi-Karchin J, Park AS, Qiu C, Dummer PD, Soomro I, Boustany-Kari CM, Pullen SS, Miner JH, Hu CA, Rohacs T, Inoue K, Ishibe S, Saleem MA, Palmer MB, Cuervo AM, Kopp JB, Susztak K.

Nat Med. 2017 Apr;23(4):429-438. doi: 10.1038/nm.4287. Epub 2017 Feb 20.

45.

Genome-Wide Association of Copy Number Polymorphisms and Kidney Function.

Li M, Carey J, Cristiano S, Susztak K, Coresh J, Boerwinkle E, Kao WH, Beaty TH, Köttgen A, Scharpf RB.

PLoS One. 2017 Jan 30;12(1):e0170815. doi: 10.1371/journal.pone.0170815. eCollection 2017.

46.

Developing Treatments for Chronic Kidney Disease in the 21st Century.

Breyer MD, Susztak K.

Semin Nephrol. 2016 Nov;36(6):436-447. doi: 10.1016/j.semnephrol.2016.08.001. Review.

47.

Absence of miR-146a in Podocytes Increases Risk of Diabetic Glomerulopathy via Up-regulation of ErbB4 and Notch-1.

Lee HW, Khan SQ, Khaliqdina S, Altintas MM, Grahammer F, Zhao JL, Koh KH, Tardi NJ, Faridi MH, Geraghty T, Cimbaluk DJ, Susztak K, Moita LF, Baltimore D, Tharaux PL, Huber TB, Kretzler M, Bitzer M, Reiser J, Gupta V.

J Biol Chem. 2017 Jan 13;292(2):732-747. doi: 10.1074/jbc.M116.753822. Epub 2016 Dec 2.

48.

Notch Pathway Is Activated via Genetic and Epigenetic Alterations and Is a Therapeutic Target in Clear Cell Renal Cancer.

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