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Items: 20

1.

Characterization of FcγRIIIA effector cells used in in vitro ADCC bioassay: Comparison of primary NK cells with engineered NK-92 and Jurkat T cells.

Hsieh YT, Aggarwal P, Cirelli D, Gu L, Surowy T, Mozier NM.

J Immunol Methods. 2017 Feb;441:56-66. doi: 10.1016/j.jim.2016.12.002. Epub 2016 Dec 8.

PMID:
27939300
2.

Development of a robust reporter-based ADCC assay with frozen, thaw-and-use cells to measure Fc effector function of therapeutic antibodies.

Cheng ZJ, Garvin D, Paguio A, Moravec R, Engel L, Fan F, Surowy T.

J Immunol Methods. 2014 Dec 1;414:69-81. doi: 10.1016/j.jim.2014.07.010. Epub 2014 Jul 31.

PMID:
25086226
3.

Serum amyloid P inhibits fibrosis through Fc gamma R-dependent monocyte-macrophage regulation in vivo.

Castaño AP, Lin SL, Surowy T, Nowlin BT, Turlapati SA, Patel T, Singh A, Li S, Lupher ML Jr, Duffield JS.

Sci Transl Med. 2009 Nov 4;1(5):5ra13. doi: 10.1126/scitranslmed.3000111. Erratum in: Sci Transl Med. 2009 Nov 4;1(5):5ra13.

4.

Discovery of piperidine-aryl urea-based stearoyl-CoA desaturase 1 inhibitors.

Xin Z, Zhao H, Serby MD, Liu B, Liu M, Szczepankiewicz BG, Nelson LT, Smith HT, Suhar TS, Janis RS, Cao N, Camp HS, Collins CA, Sham HL, Surowy TK, Liu G.

Bioorg Med Chem Lett. 2008 Aug 1;18(15):4298-302. doi: 10.1016/j.bmcl.2008.06.088. Epub 2008 Jun 28.

PMID:
18632269
5.

Liver-specific knockdown of JNK1 up-regulates proliferator-activated receptor gamma coactivator 1 beta and increases plasma triglyceride despite reduced glucose and insulin levels in diet-induced obese mice.

Yang R, Wilcox DM, Haasch DL, Jung PM, Nguyen PT, Voorbach MJ, Doktor S, Brodjian S, Bush EN, Lin E, Jacobson PB, Collins CA, Landschulz KT, Trevillyan JM, Rondinone CM, Surowy TK.

J Biol Chem. 2007 Aug 3;282(31):22765-74. Epub 2007 Jun 5.

6.

Discovery of potent, selective, orally bioavailable stearoyl-CoA desaturase 1 inhibitors.

Liu G, Lynch JK, Freeman J, Liu B, Xin Z, Zhao H, Serby MD, Kym PR, Suhar TS, Smith HT, Cao N, Yang R, Janis RS, Krauser JA, Cepa SP, Beno DW, Sham HL, Collins CA, Surowy TK, Camp HS.

J Med Chem. 2007 Jun 28;50(13):3086-100. Epub 2007 May 27.

PMID:
17530838
7.

Hepatic knockdown of stearoyl-CoA desaturase 1 via RNA interference in obese mice decreases lipid content and changes fatty acid composition.

Xu H, Wilcox D, Nguyen P, Voorbach M, Smith H, Brodjian S, Suhar T, Reilly RM, Jacobson PB, Collins CA, Landschulz K, Surowy TK.

Front Biosci. 2007 May 1;12:3781-94.

PMID:
17485339
8.

Discovery of 1-(4-phenoxypiperidin-1-yl)-2-arylaminoethanone stearoyl-CoA desaturase 1 inhibitors.

Zhao H, Serby MD, Smith HT, Cao N, Suhar TS, Surowy TK, Camp HS, Collins CA, Sham HL, Liu G.

Bioorg Med Chem Lett. 2007 Jun 15;17(12):3388-91. Epub 2007 Apr 5.

PMID:
17434733
9.

Hepatic knockdown of mitochondrial GPAT1 in ob/ob mice improves metabolic profile.

Xu H, Wilcox D, Nguyen P, Voorbach M, Suhar T, Morgan SJ, An WF, Ge L, Green J, Wu Z, Gimeno RE, Reilly R, Jacobson PB, Collins CA, Landschulz K, Surowy T.

Biochem Biophys Res Commun. 2006 Oct 13;349(1):439-48. Epub 2006 Aug 22.

PMID:
16935266
10.

Delivery of RNAi reagents in murine models of obesity and diabetes.

Wilcox DM, Yang R, Morgan SJ, Nguyen PT, Voorbach MJ, Jung PM, Haasch DL, Lin E, Bush EN, Opgenorth TJ, Jacobson PB, Collins CA, Rondinone CM, Surowy T, Landschulz KT.

J RNAi Gene Silencing. 2006 Nov 29;3(1):225-36.

11.

Seroprevalence of GB virus C and persistence of RNA and antibody.

Gutierrez RA, Dawson GJ, Knigge MF, Melvin SL, Heynen CA, Kyrk CR, Young CE, Carrick RJ, Schlauder GG, Surowy TK, Dille BJ, Coleman PF, Thiele DL, Lentino JR, Pachucki C, Mushahwar IK.

J Med Virol. 1997 Oct;53(2):167-73.

PMID:
9334929
12.

GB virus C E2 glycoprotein: expression in CHO cells, purification and characterization.

Surowy TK, Leary TP, Carrick RJ, Knigge MF, Pilot-Matias TJ, Heynen C, Gutierrez RA, Desai SM, Dawson GJ, Mushahwar IK.

J Gen Virol. 1997 Aug;78 ( Pt 8):1851-9.

PMID:
9266979
13.

An ELISA for detection of antibodies to the E2 protein of GB virus C.

Dille BJ, Surowy TK, Gutierrez RA, Coleman PF, Knigge MF, Carrick RJ, Aach RD, Hollinger FB, Stevens CE, Barbosa LH, Nemo GJ, Mosley JW, Dawson GJ, Mushahwar IK.

J Infect Dis. 1997 Feb;175(2):458-61.

PMID:
9203673
14.

Expression of the GB virus C E2 glycoprotein using the Semliki Forest virus vector system and its utility as a serologic marker.

Pilot-Matias TJ, Carrick RJ, Coleman PF, Leary TP, Surowy TK, Simons JN, Muerhoff AS, Buijk SL, Chalmers ML, Dawson GJ, Desai SM, Mushahwar IK.

Virology. 1996 Nov 15;225(2):282-92.

15.

Modulation of enzyme activity by antibody binding to an alkaline phosphatase-epitope hybrid protein.

Brennan C, Christianson K, Surowy T, Mandecki W.

Protein Eng. 1994 Apr;7(4):509-14.

PMID:
7518083
17.
18.

Antigenic sites of human growth hormone and related molecules detected by monoclonal antibodies to human growth hormone.

Surowy TK, Bartholomew RM, VanderLaan WP.

Mol Immunol. 1984 May;21(5):345-52.

PMID:
6204193
19.

Size heterogeneity of prolactin secreted from and stored in the rat anterior pituitary gland in vitro.

Bentley AM, Surowy TK, Wallis M.

Biosci Rep. 1984 Feb;4(2):129-37.

PMID:
6713084
20.

Binding specificity of monoclonal antibodies towards the size variants of human growth hormone.

Wallis M, Ivanyi J, Surowy TK.

Mol Cell Endocrinol. 1982 Nov-Dec;28(3):363-72.

PMID:
6185372

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