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Items: 1 to 50 of 67

1.

Identification of peracetylated quercetin as a selective 12-lipoxygenase pathway inhibitor in human platelets.

Doucet MS, Jougleux JL, Poirier SJ, Cormier M, Leger JL, Surette ME, Pichaud N, Touaibia M, Boudreau LH.

Mol Pharmacol. 2018 Nov 7. pii: mol.118.113480. doi: 10.1124/mol.118.113480. [Epub ahead of print]

2.

5-lipoxygenase-dependent biosynthesis of novel 20:4 n-3 metabolites with anti-inflammatory activity.

Gagnon KJ, Lefort N, Poirier SJ, Barnett DA, Surette ME.

Prostaglandins Leukot Essent Fatty Acids. 2018 Nov;138:38-44. doi: 10.1016/j.plefa.2018.10.005. Epub 2018 Oct 16.

PMID:
30392579
3.

Polyunsaturated fatty acid elongation and desaturation in activated human T cells: ELOVL5 is the key elongase.

Robichaud PP, Munganyiki JE, Boilard E, Surette ME.

J Lipid Res. 2018 Oct 6. pii: jlr.M090050. doi: 10.1194/jlr.M090050. [Epub ahead of print]

4.

Ground flaxseed reverses protection of a reduced fat diet against Citrobacter rodentium-induced colitis.

Määttänen P, Lurz E, Botts SR, Wu RY, Yeung CW, Li B, Abiff S, Johnson-Henry KC, Lepp D, Power KA, Pierro A, Surette ME, Sherman PM.

Am J Physiol Gastrointest Liver Physiol. 2018 Aug 10. doi: 10.1152/ajpgi.00101.2018. [Epub ahead of print]

PMID:
30095298
5.

Sinapic acid phenethyl ester as a potent selective 5-lipoxygenase inhibitor: Synthesis and structure-activity relationship.

Touaibia M, Hébert MJG, Levesque NA, Doiron JA, Doucet MS, Jean-François J, Cormier M, Boudreau LH, Surette ME.

Chem Biol Drug Des. 2018 Nov;92(5):1876-1887. doi: 10.1111/cbdd.13360. Epub 2018 Jul 18.

PMID:
29953727
6.

Impact of maternal iron deficiency on the auditory functions in the young and adult guinea pig.

Shero N, Fiset S, Blakley B, Jougleux JL, Surette ME, Thabet M, Rioux FM.

Nutr Neurosci. 2017 Dec 3:1-9. doi: 10.1080/1028415X.2017.1408946. [Epub ahead of print]

PMID:
29198184
7.

Substituted Caffeic and Ferulic Acid Phenethyl Esters: Synthesis, Leukotrienes Biosynthesis Inhibition, and Cytotoxic Activity.

Morin P, St-Coeur PD, Doiron JA, Cormier M, Poitras JJ, Surette ME, Touaibia M.

Molecules. 2017 Jul 6;22(7). pii: E1124. doi: 10.3390/molecules22071124.

8.

New Hydroxycinnamic Acid Esters as Novel 5-Lipoxygenase Inhibitors That Affect Leukotriene Biosynthesis.

Boudreau LH, Lassalle-Claux G, Cormier M, Blanchard S, Doucet MS, Surette ME, Touaibia M.

Mediators Inflamm. 2017;2017:6904634. doi: 10.1155/2017/6904634. Epub 2017 Jun 7.

9.

17β-estradiol-induced ACSL4 protein expression promotes an invasive phenotype in estrogen receptor positive mammary carcinoma cells.

Belkaid A, Ouellette RJ, Surette ME.

Carcinogenesis. 2017 Apr 1;38(4):402-410. doi: 10.1093/carcin/bgx020.

PMID:
28334272
11.

Structure-activity relationship of caffeic acid phenethyl ester analogs as new 5-lipoxygenase inhibitors.

Doiron JA, Leblanc LM, Hébert MJ, Levesque NA, Paré AF, Jean-François J, Cormier M, Surette ME, Touaibia M.

Chem Biol Drug Des. 2017 Apr;89(4):514-528. doi: 10.1111/cbdd.12874. Epub 2016 Nov 15.

PMID:
27717142
12.

On the cellular metabolism of the click chemistry probe 19-alkyne arachidonic acid.

Robichaud PP, Poirier SJ, Boudreau LH, Doiron JA, Barnett DA, Boilard E, Surette ME.

J Lipid Res. 2016 Oct;57(10):1821-1830. Epub 2016 Aug 18.

13.

Metabolic Effect of Estrogen Receptor Agonists on Breast Cancer Cells in the Presence or Absence of Carbonic Anhydrase Inhibitors.

Belkaid A, Čuperlović-Culf M, Touaibia M, Ouellette RJ, Surette ME.

Metabolites. 2016 May 26;6(2). pii: E16. doi: 10.3390/metabo6020016.

14.
15.

Prenatal Iron Deficiency in Guinea Pigs Increases Locomotor Activity but Does Not Influence Learning and Memory.

Fiset C, Rioux FM, Surette ME, Fiset S.

PLoS One. 2015 Jul 17;10(7):e0133168. doi: 10.1371/journal.pone.0133168. eCollection 2015.

16.

The Intracellular Localisation and Phosphorylation Profile of the Human 5-Lipoxygenase Δ13 Isoform Differs from That of Its Full Length Counterpart.

Allain EP, Boudreau LH, Flamand N, Surette ME.

PLoS One. 2015 Jul 14;10(7):e0132607. doi: 10.1371/journal.pone.0132607. eCollection 2015.

17.

17β-estradiol induces stearoyl-CoA desaturase-1 expression in estrogen receptor-positive breast cancer cells.

Belkaid A, Duguay SR, Ouellette RJ, Surette ME.

BMC Cancer. 2015 May 29;15:440. doi: 10.1186/s12885-015-1452-1.

18.

Synthesis and biological activity of arylspiroborate salts derived from caffeic Acid phenethyl ester.

Hébert MJ, Flewelling AJ, Clark TN, Levesque NA, Jean-François J, Surette ME, Gray CA, Vogels CM, Touaibia M, Westcott SA.

Int J Med Chem. 2015;2015:418362. doi: 10.1155/2015/418362. Epub 2015 Mar 5.

19.

Polyunsaturated fatty acid-phospholipid remodeling and inflammation.

Robichaud PP, Surette ME.

Curr Opin Endocrinol Diabetes Obes. 2015 Apr;22(2):112-8. doi: 10.1097/MED.0000000000000138. Review.

PMID:
25692925
20.

Clicked cinnamic/caffeic esters and amides as radical scavengers and 5-lipoxygenase inhibitors.

Doiron JA, Métayer B, Richard RR, Desjardins D, Boudreau LH, Levesque NA, Jean-François J, Poirier SJ, Surette ME, Touaibia M.

Int J Med Chem. 2014;2014:931756. doi: 10.1155/2014/931756. Epub 2014 Feb 18.

21.

Dietary LC-PUFA in iron-deficient anaemic pregnant and lactating guinea pigs induce minor defects in the offsprings' auditory brainstem responses.

Jougleux JL, Rioux FM, Church MW, Fiset S, Jacques H, Surette ME.

Nutr Neurosci. 2016 Dec;19(10):447-460. Epub 2016 Mar 10.

PMID:
25138699
22.

Antiproliferative, antiandrogenic and cytotoxic effects of novel caffeic acid derivatives in LNCaP human androgen-dependent prostate cancer cells.

Sanderson JT, Clabault H, Patton C, Lassalle-Claux G, Jean-François J, Paré AF, Hébert MJ, Surette ME, Touaibia M.

Bioorg Med Chem. 2013 Nov 15;21(22):7182-93. doi: 10.1016/j.bmc.2013.08.057. Epub 2013 Sep 6.

PMID:
24080105
23.

Fatty acid remodeling in cellular glycerophospholipids following the activation of human T cells.

Robichaud PP, Boulay K, Munganyiki JÉ, Surette ME.

J Lipid Res. 2013 Oct;54(10):2665-77. doi: 10.1194/jlr.M037044. Epub 2013 Jul 26.

24.

Mild iron deficiency anaemia during pregnancy and lactation in guinea pigs alters amplitudes and auditory nerve velocity, but not brainstem transmission times in the offspring's auditory brainstem response.

Jougleux JL, Rioux FM, Church MW, Fiset S, Surette ME.

Nutr Neurosci. 2014 Jan;17(1):37-47. doi: 10.1179/1476830513Y.0000000067. Epub 2013 Nov 26.

PMID:
23602121
25.

NMR metabolomics analysis of the effects of 5-lipoxygenase inhibitors on metabolism in glioblastomas.

Morin P Jr, Ferguson D, LeBlanc LM, Hébert MJ, Paré AF, Jean-François J, Surette ME, Touaibia M, Cuperlovic-Culf M.

J Proteome Res. 2013 May 3;12(5):2165-76. doi: 10.1021/pr400026q. Epub 2013 Apr 22.

PMID:
23557402
26.

Dietary omega-3 PUFA and health: stearidonic acid-containing seed oils as effective and sustainable alternatives to traditional marine oils.

Surette ME.

Mol Nutr Food Res. 2013 May;57(5):748-59. doi: 10.1002/mnfr.201200706. Epub 2013 Feb 18. Review.

PMID:
23417895
27.

Synthesis and antiradical/antioxidant activities of caffeic acid phenethyl ester and its related propionic, acetic, and benzoic acid analogues.

LeBlanc LM, Paré AF, Jean-François J, Hébert MJ, Surette ME, Touaibia M.

Molecules. 2012 Dec 10;17(12):14637-50. doi: 10.3390/molecules171214637.

28.

Caffeic acid phenethyl ester and its amide analogue are potent inhibitors of leukotriene biosynthesis in human polymorphonuclear leukocytes.

Boudreau LH, Maillet J, LeBlanc LM, Jean-François J, Touaibia M, Flamand N, Surette ME.

PLoS One. 2012;7(2):e31833. doi: 10.1371/journal.pone.0031833. Epub 2012 Feb 9.

29.

Mild maternal iron deficiency anemia during pregnancy and lactation in guinea pigs causes abnormal auditory function in the offspring.

Jougleux JL, Rioux FM, Church MW, Fiset S, Surette ME.

J Nutr. 2011 Jul;141(7):1390-5. doi: 10.3945/jn.110.135715. Epub 2011 May 25. Erratum in: J Nutr. 2012 Aug;142(8):1613.

PMID:
21613451
30.

Novel 5-lipoxygenase isoforms affect the biosynthesis of 5-lipoxygenase products.

Boudreau LH, Bertin J, Robichaud PP, Laflamme M, Ouellette RJ, Flamand N, Surette ME.

FASEB J. 2011 Mar;25(3):1097-105. doi: 10.1096/fj.10-173856. Epub 2010 Nov 23.

PMID:
21098726
31.

Maternal iron deficiency alters essential fatty acid and eicosanoid metabolism and increases locomotion in adult guinea pig offspring.

LeBlanc CP, Fiset S, Surette ME, Turgeon O'Brien H, Rioux FM.

J Nutr. 2009 Sep;139(9):1653-9. doi: 10.3945/jn.109.106013. Epub 2009 Jul 29.

PMID:
19640965
32.

Maternal iron deficiency and its effect on essential fatty acid and eicosanoid metabolism and spatial memory in the guinea pig offspring.

Leblanc CP, Surette ME, Fiset S, Turgeon O'Brien H, Rioux FM.

Prostaglandins Leukot Essent Fatty Acids. 2009 Jul;81(1):1-8. doi: 10.1016/j.plefa.2009.05.023. Epub 2009 Jun 12.

PMID:
19524424
33.

Synthesis and 5-lipoxygenase inhibitory activity of new cinnamoyl and caffeoyl clusters.

Doiron J, Boudreau LH, Picot N, Villebonet B, Surette ME, Touaibia M.

Bioorg Med Chem Lett. 2009 Feb 15;19(4):1118-21. doi: 10.1016/j.bmcl.2008.12.108. Epub 2009 Jan 3.

PMID:
19152786
34.

The science behind dietary omega-3 fatty acids.

Surette ME.

CMAJ. 2008 Jan 15;178(2):177-80. doi: 10.1503/cmaj.071356. No abstract available.

35.

The impact of a medical food containing gammalinolenic and eicosapentaenoic acids on asthma management and the quality of life of adult asthma patients.

Surette ME, Stull D, Lindemann J.

Curr Med Res Opin. 2008 Feb;24(2):559-67. doi: 10.1185/030079908X273011 .

PMID:
18194593
36.

Arachidonic acid regulates the translocation of 5-lipoxygenase to the nuclear membranes in human neutrophils.

Flamand N, Lefebvre J, Surette ME, Picard S, Borgeat P.

J Biol Chem. 2006 Jan 6;281(1):129-36. Epub 2005 Nov 7.

37.
38.
39.

Inhibition of leukotriene synthesis, pharmacokinetics, and tolerability of a novel dietary fatty acid formulation in healthy adult subjects.

Surette ME, Koumenis IL, Edens MB, Tramposch KM, Chilton FH.

Clin Ther. 2003 Mar;25(3):948-71.

PMID:
12852710
40.
41.

Interaction of low molecular weight group IIA phospholipase A2 with apoptotic human T cells: role of heparan sulfate proteoglycans.

Boilard E, Bourgoin SG, Bernatchez C, Poubelle PE, Surette ME.

FASEB J. 2003 Jun;17(9):1068-80.

PMID:
12773489
42.

Diet and asthma: has the role of dietary lipids been overlooked in the management of asthma?

Spector SL, Surette ME.

Ann Allergy Asthma Immunol. 2003 Apr;90(4):371-7; quiz 377-8, 421. Review.

PMID:
12722956
43.

Cyclic AMP-mediated inhibition of 5-lipoxygenase translocation and leukotriene biosynthesis in human neutrophils.

Flamand N, Surette ME, Picard S, Bourgoin S, Borgeat P.

Mol Pharmacol. 2002 Aug;62(2):250-6.

45.

Adenosine, a potent natural suppressor of arachidonic acid release and leukotriene biosynthesis in human neutrophils.

Flamand N, Boudreault S, Picard S, Austin M, Surette ME, Plante H, Krump E, Vallée MJ, Gilbert C, Naccache P, Laviolette M, Borgeat P.

Am J Respir Crit Care Med. 2000 Feb;161(2 Pt 2):S88-94. Review. No abstract available.

PMID:
10673234
47.

Perturbations in the control of cellular arachidonic acid levels block cell growth and induce apoptosis in HL-60 cells.

Surette ME, Fonteh AN, Bernatchez C, Chilton FH.

Carcinogenesis. 1999 May;20(5):757-63.

PMID:
10334191
48.
49.
50.

Dietary supplementation with gamma-linolenic acid alters fatty acid content and eicosanoid production in healthy humans.

Johnson MM, Swan DD, Surette ME, Stegner J, Chilton T, Fonteh AN, Chilton FH.

J Nutr. 1997 Aug;127(8):1435-44.

PMID:
9237935

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