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Items: 1 to 50 of 68


Development of the triazole-fused pyrimidine derivatives as highly potent and reversible inhibitors of histone lysine specific demethylase 1 (LSD1/KDM1A).

Li Z, Ding L, Li Z, Wang Z, Suo F, Shen D, Zhao T, Sun X, Wang J, Liu Y, Ma L, Zhao B, Geng P, Yu B, Zheng Y, Liu H.

Acta Pharm Sin B. 2019 Jul;9(4):794-808. doi: 10.1016/j.apsb.2019.01.001. Epub 2019 Jan 5.


Intraspecific diversity of fission yeast mitochondrial genomes.

Tao YT, Suo F, Tusso S, Wang YK, Huang S, Wolf JBW, Du LL.

Genome Biol Evol. 2019 Jul 31. pii: evz165. doi: 10.1093/gbe/evz165. [Epub ahead of print]


Rapid removal of triazine pesticides by P doped biochar and the adsorption mechanism.

Suo F, You X, Ma Y, Li Y.

Chemosphere. 2019 Jun 21;235:918-925. doi: 10.1016/j.chemosphere.2019.06.158. [Epub ahead of print]


Correction to: Time to positivity of blood culture is a risk factor for clinical outcomes in Staphylococcus aureus bacteremia children: a retrospective study.

Li Y, Li Q, Zhang G, Ma H, Wu Y, Yi Q, Jiang L, Wan J, Suo F, Luo Z.

BMC Infect Dis. 2019 Jul 11;19(1):608. doi: 10.1186/s12879-019-4194-x.


High developmental pluripotency‑associated 4 expression promotes cell proliferation and glycolysis, and predicts poor prognosis in non‑small‑cell lung cancer.

Li L, Wang Y, Wang Q, Qu J, Wei X, Xu J, Wang Y, Suo F, Zhang Y.

Mol Med Rep. 2019 Jul;20(1):445-454. doi: 10.3892/mmr.2019.10272. Epub 2019 May 22.


Development of a novel strategy for robust synthetic bacterial promoters based on a stepwise evolution targeting the spacer region of the core promoter in Bacillus subtilis.

Han L, Cui W, Suo F, Miao S, Hao W, Chen Q, Guo J, Liu Z, Zhou L, Zhou Z.

Microb Cell Fact. 2019 May 29;18(1):96. doi: 10.1186/s12934-019-1148-3.


Time to positivity of blood culture is a risk factor for clinical outcomes in Staphylococcus aureus bacteremia children: a retrospective study.

Li Y, Li Q, Zhang G, Ma H, Wu Y, Yi Q, Jiang L, Wan J, Suo F, Luo Z.

BMC Infect Dis. 2019 May 17;19(1):437. doi: 10.1186/s12879-019-3993-4. Erratum in: BMC Infect Dis. 2019 Jul 11;19(1):608.


Discovery and synthesis of novel indole derivatives-containing 3-methylenedihydrofuran-2(3H)-one as irreversible LSD1 inhibitors.

Liu HM, Suo FZ, Li XB, You YH, Lv CT, Zheng CX, Zhang GC, Liu YJ, Kang WT, Zheng YC, Xu HW.

Eur J Med Chem. 2019 Aug 1;175:357-372. doi: 10.1016/j.ejmech.2019.04.065. Epub 2019 Apr 29.


[Study of mycelial polysaccharide from Paraisaria dubia of Ophiocordyceps gracilis asexual].

Wang Y, Li ZL, Suo FY, Sun DP.

Zhongguo Zhong Yao Za Zhi. 2019 Apr;44(8):1704-1709. doi: 10.19540/j.cnki.cjcmm.20190318.201. Chinese.


Synthesis and biological evaluation of vanadium complexes as novel anti-tumor agents.

Lu LP, Suo FZ, Feng YL, Song LL, Li Y, Li YJ, Wang KT.

Eur J Med Chem. 2019 Aug 15;176:1-10. doi: 10.1016/j.ejmech.2019.04.073. Epub 2019 May 7.


Sanggenon O induced apoptosis of A549 cells is counterbalanced by protective autophagy.

Li ZR, Ma T, Guo YJ, Hu B, Niu SH, Suo FZ, Du LN, You YH, Kang WT, Liu S, Mamun M, Song QM, Pang JR, Zheng YC, Liu HM.

Bioorg Chem. 2019 Jun;87:688-698. doi: 10.1016/j.bioorg.2019.03.072. Epub 2019 Apr 4.


Systematic analysis reveals the prevalence and principles of bypassable gene essentiality.

Li J, Wang HT, Wang WT, Zhang XR, Suo F, Ren JY, Bi Y, Xue YX, Hu W, Dong MQ, Du LL.

Nat Commun. 2019 Mar 1;10(1):1002. doi: 10.1038/s41467-019-08928-1.


Synthesis, structure-activity relationship studies and biological characterization of new [1,2,4]triazolo[1,5-a]pyrimidine-based LSD1/KDM1A inhibitors.

Wang S, Li ZR, Suo FZ, Yuan XH, Yu B, Liu HM.

Eur J Med Chem. 2019 Apr 1;167:388-401. doi: 10.1016/j.ejmech.2019.02.039. Epub 2019 Feb 13.


Experience-based discovery (EBD) of aryl hydrazines as new scaffolds for the development of LSD1/KDM1A inhibitors.

Li ZR, Wang S, Yang L, Yuan XH, Suo FZ, Yu B, Liu HM.

Eur J Med Chem. 2019 Mar 15;166:432-444. doi: 10.1016/j.ejmech.2019.01.075. Epub 2019 Feb 2.


Prognostic roles of time to positivity of blood culture in children with Streptococcus pneumoniae bacteremia.

Li Q, Li Y, Yi Q, Suo F, Tang Y, Luo S, Tian X, Zhang G, Chen D, Luo Z.

Eur J Clin Microbiol Infect Dis. 2019 Mar;38(3):457-465. doi: 10.1007/s10096-018-03443-5. Epub 2019 Jan 24.


Contrast of diagnostic value between IL-17 combined with IL-18 and CT angiography in carotid atherosclerosis.

Suo F, Jiang F, Fang X, Ma A, Ma L.

Exp Ther Med. 2019 Feb;17(2):1400-1404. doi: 10.3892/etm.2018.7088. Epub 2018 Dec 12.


Identification of osimertinib (AZD9291) as a lysine specific demethylase 1 inhibitor.

Li ZR, Suo FZ, Hu B, Guo YJ, Fu DJ, Yu B, Zheng YC, Liu HM.

Bioorg Chem. 2019 Mar;84:164-169. doi: 10.1016/j.bioorg.2018.11.018. Epub 2018 Nov 16.


USP28 contributes to the proliferation and metastasis of gastric cancer.

Zhao LJ, Zhang T, Feng XJ, Chang J, Suo FZ, Ma JL, Liu YJ, Liu Y, Zheng YC, Liu HM.

J Cell Biochem. 2018 Nov 28. doi: 10.1002/jcb.28040. [Epub ahead of print]


Design, synthesis and in vitro evaluation of stilbene derivatives as novel LSD1 inhibitors for AML therapy.

Duan Y, Qin W, Suo F, Zhai X, Guan Y, Wang X, Zheng Y, Liu H.

Bioorg Med Chem. 2018 Dec 15;26(23-24):6000-6014. doi: 10.1016/j.bmc.2018.10.037. Epub 2018 Oct 29.


Mesoporous activated carbon from starch for superior rapid pesticides removal.

Suo F, Liu X, Li C, Yuan M, Zhang B, Wang J, Ma Y, Lai Z, Ji M.

Int J Biol Macromol. 2019 Jan;121:806-813. doi: 10.1016/j.ijbiomac.2018.10.132. Epub 2018 Oct 17.


Development of formaldehyde dehydrogenase-coupled assay and antibody-based assays for ALKBH5 activity evaluation.

Shen DD, Suo FZ, Song QM, Chang J, Zhang T, Hong JJ, Zheng YC, Liu HM.

J Pharm Biomed Anal. 2019 Jan 5;162:9-15. doi: 10.1016/j.jpba.2018.09.018. Epub 2018 Sep 7.


Application of karyotype analysis combined with BACs-on-Beads for prenatal diagnosis.

Fang Y, Wang G, Gu L, Wang J, Suo F, Gu M, Gou L.

Exp Ther Med. 2018 Oct;16(4):2895-2900. doi: 10.3892/etm.2018.6574. Epub 2018 Aug 6.


Exploitation of Bacillus subtilis as a robust workhorse for production of heterologous proteins and beyond.

Cui W, Han L, Suo F, Liu Z, Zhou L, Zhou Z.

World J Microbiol Biotechnol. 2018 Sep 10;34(10):145. doi: 10.1007/s11274-018-2531-7. Review.


Tdp1 processes chromate-induced single-strand DNA breaks that collapse replication forks.

Ganguly A, Guo L, Sun L, Suo F, Du LL, Russell P.

PLoS Genet. 2018 Aug 27;14(8):e1007595. doi: 10.1371/journal.pgen.1007595. eCollection 2018 Aug.


Stepwise modifications of genetic parts reinforce the secretory production of nattokinase in Bacillus subtilis.

Cui W, Suo F, Cheng J, Han L, Hao W, Guo J, Zhou Z.

Microb Biotechnol. 2018 Sep;11(5):930-942. doi: 10.1111/1751-7915.13298. Epub 2018 Jul 8.


Non-invasive prenatal testing in detecting sex chromosome aneuploidy: A large-scale study in Xuzhou area of China.

Suo F, Wang C, Liu T, Fang Y, Wu Q, Gu M, Gou L.

Clin Chim Acta. 2018 Jun;481:139-141. doi: 10.1016/j.cca.2018.03.007. Epub 2018 Mar 12.


Impact of childhood wheezing on lung function in adulthood: A meta-analysis.

Ma H, Li Y, Tang L, Peng X, Jiang L, Wan J, Suo F, Zhang G, Luo Z.

PLoS One. 2018 Feb 2;13(2):e0192390. doi: 10.1371/journal.pone.0192390. eCollection 2018.


Lysine-specific demethylase 1 activation by vitamin B2 attenuates efficacy of apatinib for proliferation and migration of gastric cancer cell MGC-803.

Ma JL, Zhang T, Suo FZ, Chang J, Wan XB, Feng XJ, Zheng YC, Liu HM.

J Cell Biochem. 2018 Jun;119(6):4957-4966. doi: 10.1002/jcb.26741. Epub 2018 Mar 9.


Discovery of tranylcypromine analogs with an acylhydrazone substituent as LSD1 inactivators: Design, synthesis and their biological evaluation.

Sun K, Peng JD, Suo FZ, Zhang T, Fu YD, Zheng YC, Liu HM.

Bioorg Med Chem Lett. 2017 Nov 15;27(22):5036-5039. doi: 10.1016/j.bmcl.2017.10.003. Epub 2017 Oct 3.


A large gene family in fission yeast encodes spore killers that subvert Mendel's law.

Hu W, Jiang ZD, Suo F, Zheng JX, He WZ, Du LL.

Elife. 2017 Jun 20;6. pii: e26057. doi: 10.7554/eLife.26057.


SUMO-Targeted DNA Translocase Rrp2 Protects the Genome from Top2-Induced DNA Damage.

Wei Y, Diao LX, Lu S, Wang HT, Suo F, Dong MQ, Du LL.

Mol Cell. 2017 Jun 1;66(5):581-596.e6. doi: 10.1016/j.molcel.2017.04.017. Epub 2017 May 25.


An Overview on Screening Methods for Lysine Specific Demethylase 1 (LSD1) Inhibitors.

Zheng YC, Chang J, Zhang T, Suo FZ, Chen XB, Liu Y, Zhao B, Yu B, Liu HM.

Curr Med Chem. 2017;24(23):2496-2504. doi: 10.2174/0929867324666170509114321. Review.


Discovery of [1,2,3]Triazolo[4,5-d]pyrimidine Derivatives as Novel LSD1 Inhibitors.

Li ZH, Liu XQ, Geng PF, Suo FZ, Ma JL, Yu B, Zhao TQ, Zhou ZQ, Huang CX, Zheng YC, Liu HM.

ACS Med Chem Lett. 2017 Mar 6;8(4):384-389. doi: 10.1021/acsmedchemlett.6b00423. eCollection 2017 Apr 13.


Application of gene detection technique in the antenatal diagnosis of hereditary hearing loss.

Fang Y, Gu MS, Suo F, Wang CX, Liu XH, Liu FM.

Eur Rev Med Pharmacol Sci. 2017 Apr;21(7):1452-1455.


The effect of miR-146a on STAT1 expression and apoptosis in acute lymphoblastic leukemia Jurkat cells.

Yan W, Guo H, Suo F, Han C, Zheng H, Chen T.

Oncol Lett. 2017 Jan;13(1):151-154. doi: 10.3892/ol.2016.5395. Epub 2016 Nov 18.


Global Fitness Profiling Identifies Arsenic and Cadmium Tolerance Mechanisms in Fission Yeast.

Guo L, Ganguly A, Sun L, Suo F, Du LL, Russell P.

G3 (Bethesda). 2016 Oct 13;6(10):3317-3333. doi: 10.1534/g3.116.033829.


[Regional characteristic analysis of alkaloids and chlorogenic acid in wild Phellodendri Amurensis Cortex].

Zhang Y, Zhang ZP, Zhang Z, Bi CJ, Liu HT, Zhang Q, Huang SX, Zhang BG, Chen Y, Suo FM.

Zhongguo Zhong Yao Za Zhi. 2016 May;41(10):1797-1802. doi: 10.4268/cjcmm20161006. Chinese.


[Evaluation for heavy metal pollution of soil and herb from main producing area of Phellodendron amurense in China].

Qi YD, Zhang ZP, Zhang Z, Zhang Y, Huang SX, Zhao YJ, Suo FM, Zhang BG, Gao WR.

Zhongguo Zhong Yao Za Zhi. 2016 Feb;41(3):383-389. doi: 10.4268/cjcmm20160304. Chinese.


Bulk Segregant Analysis Reveals the Genetic Basis of a Natural Trait Variation in Fission Yeast.

Hu W, Suo F, Du LL.

Genome Biol Evol. 2015 Nov 27;7(12):3496-510. doi: 10.1093/gbe/evv238.


The Diagnosis Pattern of Mid-Trimester Fetal Chromosomal Aneuploidy in Xuzhou and the Clinical Applications.

Fang Y, Wang G, Wang C, Suo F, Gu M, Xia Y.

Cell Biochem Biophys. 2015 Nov;73(2):267-270. doi: 10.1007/s12013-015-0594-8.


GJB2 as Well as SLC26A4 Gene Mutations are Prominent Causes for Congenital Deafness.

Fang Y, Gu M, Wang C, Suo F, Wang G, Xia Y.

Cell Biochem Biophys. 2015 Sep;73(1):41-4. doi: 10.1007/s12013-015-0562-3.


Parallel profiling of fission yeast deletion mutants for proliferation and for lifespan during long-term quiescence.

Sideri T, Rallis C, Bitton DA, Lages BM, Suo F, Rodríguez-López M, Du LL, Bähler J.

G3 (Bethesda). 2014 Dec 1;5(1):145-55. doi: 10.1534/g3.114.014415.


Comprehensive analysis of alternative splicing in Digitalis purpurea by strand-specific RNA-Seq.

Wu B, Suo F, Lei W, Gu L.

PLoS One. 2014 Aug 28;9(8):e106001. doi: 10.1371/journal.pone.0106001. eCollection 2014.


Natural Resource Monitoring of Rheum tanguticum by Multilevel Remote Sensing.

Xie C, Song J, Suo F, Li X, Li Y, Yu H, Xu X, Luo K, Li Q, Xin T, Guan M, Xu X, Miki E, Takeda O, Chen S.

Evid Based Complement Alternat Med. 2014;2014:618902. doi: 10.1155/2014/618902. Epub 2014 Jul 2.


Genome-wide screens for sensitivity to ionizing radiation identify the fission yeast nonhomologous end joining factor Xrc4.

Li J, Yu Y, Suo F, Sun LL, Zhao D, Du LL.

G3 (Bethesda). 2014 May 21;4(7):1297-306. doi: 10.1534/g3.114.011841.


Targeted NGF siRNA delivery attenuates sympathetic nerve sprouting and deteriorates cardiac dysfunction in rats with myocardial infarction.

Hu H, Xuan Y, Wang Y, Xue M, Suo F, Li X, Cheng W, Li X, Yin J, Liu J, Yan S.

PLoS One. 2014 Apr 22;9(4):e95106. doi: 10.1371/journal.pone.0095106. eCollection 2014.


Fine-tuning of NADH oxidase decreases byproduct accumulation in respiration deficient xylose metabolic Saccharomyces cerevisiae.

Hou J, Suo F, Wang C, Li X, Shen Y, Bao X.

BMC Biotechnol. 2014 Feb 14;14:13. doi: 10.1186/1472-6750-14-13.


Exogenous nerve growth factor promotes the repair of cardiac sympathetic heterogeneity and electrophysiological instability in diabetic rats.

Xue M, Xuan YL, Wang Y, Hu HS, Li XL, Suo F, Li XR, Cheng WJ, Yan SH.

Cardiology. 2014;127(3):155-63. doi: 10.1159/000355535. Epub 2013 Dec 12.


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