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Items: 1 to 50 of 106


Patient-derived lung cancer organoids as in vitro cancer models for therapeutic screening.

Kim M, Mun H, Sung CO, Cho EJ, Jeon HJ, Chun SM, Jung DJ, Shin TH, Jeong GS, Kim DK, Choi EK, Jeong SY, Taylor AM, Jain S, Meyerson M, Jang SJ.

Nat Commun. 2019 Sep 5;10(1):3991. doi: 10.1038/s41467-019-11867-6.


A one-stop microfluidic-based lung cancer organoid culture platform for testing drug sensitivity.

Jung DJ, Shin TH, Kim M, Sung CO, Jang SJ, Jeong GS.

Lab Chip. 2019 Sep 7;19(17):2854-2865. doi: 10.1039/c9lc00496c. Epub 2019 Aug 1.


Mesenchymal stem cells prevent the progression of diabetic nephropathy by improving mitochondrial function in tubular epithelial cells.

Lee SE, Jang JE, Kim HS, Jung MK, Ko MS, Kim MO, Park HS, Oh W, Choi SJ, Jin HJ, Kim SY, Kim YJ, Kim SW, Kim MK, Sung CO, Pack CG, Lee KU, Koh EH.

Exp Mol Med. 2019 Jul 9;51(7):77. doi: 10.1038/s12276-019-0268-5.


BioTarget: A Computational Framework Identifying Cancer Type Specific Transcriptional Targets of Immune Response Pathways.

Hoang TH, Zhao Y, Lam Y, Piekos S, Han YC, Reilly C, Joshi P, Hong SH, Sung CO, Giardina C, Shin DG.

Sci Rep. 2019 Jun 21;9(1):9029. doi: 10.1038/s41598-019-45304-x.


Immunogenomic landscape of hepatocellular carcinoma with immune cell stroma and EBV-positive tumor-infiltrating lymphocytes.

Kang HJ, Oh JH, Chun SM, Kim D, Ryu YM, Hwang HS, Kim SY, An J, Cho EJ, Lee H, Shim JH, Sung CO, Yu E.

J Hepatol. 2019 Jul;71(1):91-103. doi: 10.1016/j.jhep.2019.03.018. Epub 2019 Mar 29.


Detection of chromosome structural variation by targeted next-generation sequencing and a deep learning application.

Park H, Chun SM, Shim J, Oh JH, Cho EJ, Hwang HS, Lee JY, Kim D, Jang SJ, Nam SJ, Hwang C, Sohn I, Sung CO.

Sci Rep. 2019 Mar 6;9(1):3644. doi: 10.1038/s41598-019-40364-5.


Characterization of Hepatocellular Carcinoma Patients with FGF19 Amplification Assessed by Fluorescence in situ Hybridization: A Large Cohort Study.

Kang HJ, Haq F, Sung CO, Choi J, Hong SM, Eo SH, Jeong HJ, Shin J, Shim JH, Lee HC, An J, Kim MJ, Kim KP, Ahn SM, Yu E.

Liver Cancer. 2019 Feb;8(1):12-23. doi: 10.1159/000488541. Epub 2018 May 22.


Unstable Genome and Transcriptome Dynamics during Tumor Metastasis Contribute to Therapeutic Heterogeneity in Colorectal Cancers.

Cho SY, Chae J, Na D, Kang W, Lee A, Min S, Kang J, Choi B, Lee J, Sung CO, Chuang JH, Lee C, Lee WS, Park H, Kim JI.

Clin Cancer Res. 2019 May 1;25(9):2821-2834. doi: 10.1158/1078-0432.CCR-18-3460. Epub 2019 Jan 22.


Functional loss of ARID1A is tightly associated with high PD-L1 expression in gastric cancer.

Kim YB, Ahn JM, Bae WJ, Sung CO, Lee D.

Int J Cancer. 2019 Aug 15;145(4):916-926. doi: 10.1002/ijc.32140. Epub 2019 Feb 8.


Tumor-infiltrating immune cell subpopulations and programmed death ligand 1 (PD-L1) expression associated with clinicopathological and prognostic parameters in ependymoma.

Nam SJ, Kim YH, Park JE, Ra YS, Khang SK, Cho YH, Kim JH, Sung CO.

Cancer Immunol Immunother. 2019 Feb;68(2):305-318. doi: 10.1007/s00262-018-2278-x. Epub 2018 Nov 27.


Mutation Burden and I Index for Detection of Microsatellite Instability in Colorectal Cancer by Targeted Next-Generation Sequencing.

Kim JE, Chun SM, Hong YS, Kim KP, Kim SY, Kim J, Sung CO, Cho EJ, Kim TW, Jang SJ.

J Mol Diagn. 2019 Mar;21(2):241-250. doi: 10.1016/j.jmoldx.2018.09.005. Epub 2018 Oct 31.


Expression and prognostic significance of epithelial-mesenchymal transition-related markers and phenotype in serous ovarian cancer.

Song IH, Kim KR, Lim S, Kim SH, Sung CO.

Pathol Res Pract. 2018 Oct;214(10):1564-1571. doi: 10.1016/j.prp.2018.07.016. Epub 2018 Jul 25.


Next-Generation Sequencing Using S1 Nuclease for Poor-Quality Formalin-Fixed, Paraffin-Embedded Tumor Specimens.

Chun SM, Sung CO, Jeon H, Kim TI, Lee JY, Park H, Kim Y, Kim D, Jang SJ.

J Mol Diagn. 2018 Nov;20(6):802-811. doi: 10.1016/j.jmoldx.2018.06.002. Epub 2018 Jul 25.


Alterations in the Rho pathway contribute to Epstein-Barr virus-induced lymphomagenesis in immunosuppressed environments.

Cho SY, Sung CO, Chae J, Lee J, Na D, Kang W, Kang J, Min S, Lee A, Kwak E, Kim J, Choi B, Kim H, Chuang JH, Pak HK, Park CS, Park S, Ko YH, Lee D, Roh J, Cho MS, Park S, Ju YS, Suh YS, Kong SH, Lee HJ, Keck J, Banchereau J, Liu ET, Kim WH, Park H, Yang HK, Kim JI, Lee C.

Blood. 2018 Apr 26;131(17):1931-1941. doi: 10.1182/blood-2017-07-797209. Epub 2018 Feb 23.


The immune checkpoint molecule V-set Ig domain-containing 4 is an independent prognostic factor for multiple myeloma.

Roh J, Jeon Y, Lee AN, Lee SM, Kim Y, Sung CO, Park CJ, Hong JY, Yoon DH, Suh C, Huh J, Choi I, Park CS.

Oncotarget. 2017 Jul 22;8(35):58122-58132. doi: 10.18632/oncotarget.19468. eCollection 2017 Aug 29.


The Value of Preoperative Positron Emission Tomography/Computed Tomography in Node-Negative Endometrial Cancer on Magnetic Resonance Imaging.

Park JY, Lee JJ, Choi HJ, Song IH, Sung CO, Kim HO, Chae SY, Kim YT, Nam JH.

Ann Surg Oncol. 2017 Aug;24(8):2303-2310. doi: 10.1245/s10434-017-5901-8. Epub 2017 May 26.


Good Laboratory Standards for Clinical Next-Generation Sequencing Cancer Panel Tests.

Kim J, Park WY, Kim NKD, Jang SJ, Chun SM, Sung CO, Choi J, Ko YH, Choi YL, Shim HS, Won JK; Molecular Pathology Study Group of Korean Society of Pathologists.

J Pathol Transl Med. 2017 May;51(3):191-204. doi: 10.4132/jptm.2017.03.14. Epub 2017 May 10. Review.


SHP2 is induced by the HBx-NF-κB pathway and contributes to fibrosis during human early hepatocellular carcinoma development.

Kang HJ, Chung DH, Sung CO, Yoo SH, Yu E, Kim N, Lee SH, Song JY, Kim CJ, Choi J.

Oncotarget. 2017 Apr 18;8(16):27263-27276. doi: 10.18632/oncotarget.15930.


High prevalence of TP53 mutations is associated with poor survival and an EMT signature in gliosarcoma patients.

Cho SY, Park C, Na D, Han JY, Lee J, Park OK, Zhang C, Sung CO, Moon HE, Kim Y, Kim JH, Kim JJ, Khang SK, Nam DH, Choi JW, Suh YL, Kim DG, Park SH, Youn H, Yun K, Kim JI, Lee C, Paek SH, Park H.

Exp Mol Med. 2017 Apr 14;49(4):e317. doi: 10.1038/emm.2017.9.


Protective role of endogenous plasmalogens against hepatic steatosis and steatohepatitis in mice.

Jang JE, Park HS, Yoo HJ, Baek IJ, Yoon JE, Ko MS, Kim AR, Kim HS, Park HS, Lee SE, Kim SW, Kim SJ, Leem J, Kang YM, Jung MK, Pack CG, Kim CJ, Sung CO, Lee IK, Park JY, Fernández-Checa JC, Koh EH, Lee KU.

Hepatology. 2017 Aug;66(2):416-431. doi: 10.1002/hep.29039. Epub 2017 Jun 29. Erratum in: Hepatology. 2019 Jul;70(1):453.


Immunoprofile-based subgrouping of urothelial bladder carcinomas for survival prediction.

Kim K, Sung CO, Park BH, Ku JY, Go H, Ro JY, Kim J, Cho YM.

Hum Pathol. 2015 Oct;46(10):1464-70. doi: 10.1016/j.humpath.2015.06.003. Epub 2015 Jun 16.


Accuracy of Core Needle Biopsy Versus Fine Needle Aspiration Cytology for Diagnosing Salivary Gland Tumors.

Song IH, Song JS, Sung CO, Roh JL, Choi SH, Nam SY, Kim SY, Lee JH, Baek JH, Cho KJ.

J Pathol Transl Med. 2015 Mar;49(2):136-43. doi: 10.4132/jptm.2015.01.03. Epub 2015 Mar 12.


Clinicopathological Significance of Minimal Extrathyroid Extension in Solitary Papillary Thyroid Carcinomas.

Woo CG, Sung CO, Choi YM, Kim WG, Kim TY, Shong YK, Kim WB, Hong SJ, Song DE.

Ann Surg Oncol. 2015 Dec;22 Suppl 3:S728-33. doi: 10.1245/s10434-015-4659-0. Epub 2015 Jun 16.


Defective pericyte recruitment of villous stromal vessels as the possible etiologic cause of hydropic change in complete hydatidiform mole.

Kim KR, Sung CO, Kwon TJ, Lee J, Robboy SJ.

PLoS One. 2015 Apr 7;10(4):e0122266. doi: 10.1371/journal.pone.0122266. eCollection 2015.


Overexpression of C-reactive Protein as a Poor Prognostic Marker of Resectable Hepatocellular Carcinomas.

Shin JH, Kim CJ, Jeon EJ, Sung CO, Shin HJ, Choi J, Yu E.

J Pathol Transl Med. 2015 Mar;49(2):105-11. doi: 10.4132/jptm.2015.01.19. Epub 2015 Mar 12.


Mixed carcinoid-mucinous adenocarcinoma arising in mature teratoma of mesentery.

Shin SJ, Son EM, Sung CO, Kim KR.

J Pathol Transl Med. 2015 Jan;49(1):61-5. doi: 10.4132/jptm.2014.09.17. Epub 2015 Jan 15. No abstract available.


HIPK2 expression in progression of cutaneous epithelial neoplasm.

Kwon MJ, Min SK, Seo J, Kim DH, Sung CO, Lim MS, Cho J, Park HR.

Int J Dermatol. 2015 Mar;54(3):347-54. doi: 10.1111/ijd.12664.


Peritoneal Carcinosarcoma and Ovarian Papillary Serous Carcinoma Are the Same Origin: Analysis of TP53 Mutation and Microsatellite Suggests a Monoclonal Origin.

Woo CG, Suh DS, Kim JY, Sung CO, Choi J, Kim KR.

Korean J Pathol. 2014 Dec;48(6):449-53. doi: 10.4132/KoreanJPathol.2014.48.6.449. Epub 2014 Dec 31. No abstract available.


Expression of carbonic anhydrase 9 is a novel prognostic marker in resectable hepatocellular carcinoma.

Kang HJ, Kim IH, Sung CO, Shim JH, Yu E.

Virchows Arch. 2015 Apr;466(4):403-13. doi: 10.1007/s00428-014-1709-0. Epub 2015 Jan 11.


Twist1 is a key regulator of cancer-associated fibroblasts.

Lee KW, Yeo SY, Sung CO, Kim SH.

Cancer Res. 2015 Jan 1;75(1):73-85. doi: 10.1158/0008-5472.CAN-14-0350. Epub 2014 Nov 3.


BRAF V600E mutations are frequent in dysembryoplastic neuroepithelial tumors and subependymal giant cell astrocytomas.

Lee D, Cho YH, Kang SY, Yoon N, Sung CO, Suh YL.

J Surg Oncol. 2015 Mar;111(3):359-64. doi: 10.1002/jso.23822. Epub 2014 Oct 24.


Genomic Alterations in the RB Pathway Indicate Prognostic Outcomes of Early-Stage Lung Adenocarcinoma.

Choi S, Kim HR, Sung CO, Kim J, Kim S, Ahn SM, Choi CM, Chun SM, Choi EK, Kim SW, Kim YH, Lee JY, Song JS, Kim D, Haq F, Lee SY, Lee JE, Jung WR, Jang HY, Yang E, Lee C, Yu E, Kong G, Baek D, Jang SJ.

Clin Cancer Res. 2015 Jun 1;21(11):2613-23. doi: 10.1158/1078-0432.CCR-14-0519. Epub 2014 Oct 7.


CD10 expression is enhanced by Twist1 and associated with poor prognosis in esophageal squamous cell carcinoma with facilitating tumorigenicity in vitro and in vivo.

Lee KW, Sung CO, Kim JH, Kang M, Yoo HY, Kim HH, Um SH, Kim SH.

Int J Cancer. 2015 Jan 15;136(2):310-21. doi: 10.1002/ijc.29006. Epub 2014 Jun 26.


The expression pattern of 19 genes predicts the histology of endometrial carcinoma.

Sung CO, Sohn I.

Sci Rep. 2014 Jun 4;4:5174. doi: 10.1038/srep05174.


Genomic portrait of resectable hepatocellular carcinomas: implications of RB1 and FGF19 aberrations for patient stratification.

Ahn SM, Jang SJ, Shim JH, Kim D, Hong SM, Sung CO, Baek D, Haq F, Ansari AA, Lee SY, Chun SM, Choi S, Choi HJ, Kim J, Kim S, Hwang S, Lee YJ, Lee JE, Jung WR, Jang HY, Yang E, Sung WK, Lee NP, Mao M, Lee C, Zucman-Rossi J, Yu E, Lee HC, Kong G.

Hepatology. 2014 Dec;60(6):1972-82. doi: 10.1002/hep.27198. Epub 2014 Sep 22.


AZGP-1 immunohistochemical marker in prostate cancer: potential predictive marker of biochemical recurrence in post radical prostatectomy specimens.

Jung WY, Sung CO, Han SH, Kim K, Kim M, Ro JY, Kang MJ, Ahn H, Cho YM.

Appl Immunohistochem Mol Morphol. 2014 Oct;22(9):652-7. doi: 10.1097/PAI.0000000000000015.


A distinctive ovarian cancer molecular subgroup characterized by poor prognosis and somatic focal copy number amplifications at chromosome 19.

Sung CO, Song IH, Sohn I.

Gynecol Oncol. 2014 Feb;132(2):343-50. doi: 10.1016/j.ygyno.2013.11.036. Epub 2013 Dec 8.


Endocervical-like versus intestinal-type mucinous borderline ovarian tumors: a large retrospective series focusing on the clinicopathologic characteristics.

Song T, Choi CH, Lee YY, Kim TJ, Lee JW, Sung CO, Song SY, Bae DS, Kim BG.

Gynecol Obstet Invest. 2013;76(4):241-7. doi: 10.1159/000356072. Epub 2013 Nov 1.


High throughput molecular profiling reveals differential mutation patterns in intrahepatic cholangiocarcinomas arising in chronic advanced liver diseases.

Jang S, Chun SM, Hong SM, Sung CO, Park H, Kang HJ, Kim KP, Lee YJ, Yu E.

Mod Pathol. 2014 May;27(5):731-9. doi: 10.1038/modpathol.2013.194. Epub 2013 Nov 1.


Pulmonary metastatic nodules of uterine low-grade endometrial stromal sarcoma: histopathological and immunohistochemical analysis of 10 cases.

Park JY, Sung CO, Jang SJ, Song SY, Han JH, Kim KR.

Histopathology. 2013 Dec;63(6):833-40. doi: 10.1111/his.12232. Epub 2013 Sep 11.


Clinical relevance of gain-of-function mutations of p53 in high-grade serous ovarian carcinoma.

Kang HJ, Chun SM, Kim KR, Sohn I, Sung CO.

PLoS One. 2013 Aug 13;8(8):e72609. doi: 10.1371/journal.pone.0072609. eCollection 2013.


Integrative analysis of copy number alteration and gene expression profiling in ovarian clear cell adenocarcinoma.

Sung CO, Choi CH, Ko YH, Ju H, Choi YL, Kim N, Kang SY, Ha SY, Choi K, Bae DS, Lee JW, Kim TJ, Song SY, Kim BG.

Cancer Genet. 2013 May;206(5):145-53. doi: 10.1016/j.cancergen.2013.04.002. Epub 2013 May 29.


TWIST1 promoter methylation is associated with prognosis in tonsillar squamous cell carcinoma.

Kwon MJ, Kwon JH, Nam ES, Shin HS, Lee DJ, Kim JH, Rho YS, Sung CO, Lee WJ, Cho SJ.

Hum Pathol. 2013 Sep;44(9):1722-9. doi: 10.1016/j.humpath.2013.03.004. Epub 2013 May 10.


Clinical significance of galectin-7 in epithelial ovarian cancer.

Kim HJ, Jeon HK, Lee JK, Sung CO, Do IG, Choi CH, Kim TJ, Kim BG, Bae DS, Lee JW.

Anticancer Res. 2013 Apr;33(4):1555-61.


Sarcomatoid carcinoma represents a complete phenotype with various pathways of epithelial mesenchymal transition.

Sung CO, Choi H, Lee KW, Kim SH.

J Clin Pathol. 2013 Jul;66(7):601-6. doi: 10.1136/jclinpath-2012-201271. Epub 2013 Mar 26.


Significance of HPV-58 infection in women who are HPV-positive, cytology-negative and living in a country with a high prevalence of HPV-58 infection.

Song JS, Kim EJ, Choi J, Gong G, Sung CO.

PLoS One. 2013;8(3):e58678. doi: 10.1371/journal.pone.0058678. Epub 2013 Mar 7.


Poor prognosis of uterine serous carcinoma compared with grade 3 endometrioid carcinoma in early stage patients.

Park JY, Nam JH, Kim YT, Kim YM, Kim JH, Kim DY, Sohn I, Lee SW, Sung CO, Kim KR.

Virchows Arch. 2013 Mar;462(3):289-96. doi: 10.1007/s00428-013-1382-8. Epub 2013 Feb 17.


Primary clear cell adenocarcinoma arising from rectal endometriosis.

Min KW, Koh YW, Ryu YJ, Hong SM, Kim KR, Sung CO.

Dig Endosc. 2013 Mar;25(2):209-10. doi: 10.1111/den.12008. Epub 2012 Dec 17. No abstract available.


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